TAK1 activates NFkB by phosphorylation and activation of IKKs complex
gene
reagent
sample publication
sample review
IkappaBalpha
NFKB inhibitor alpha
total:117
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
Santa Cruz anti-I-kappa B alpha antibody was used to perform western blot in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
IKK alpha
component of inhibitor of nuclear factor kappa B kinase complex
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-IKKalpha monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
IKKbeta
inhibitor of nuclear factor kappa B kinase subunit beta
total:36
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Millipore anti-IKK2 antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
IKKgamma
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
total:21
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Santa Cruz Biotechnology anti-NEMO antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
IRAK
interleukin 1 receptor associated kinase 1
total:10
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 to the paper
Santa Cruz mouse anti-IRAK-1 was used to perform western blot in order to show that IRAK-1 blockade is important for tolerance of human DCs induced by TLR2 and TLR4 stimulation. more
NFKB2
nuclear factor kappa B subunit 2
total:11
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
New England Biolabs anti-p52/p100 (18D10) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
NFKBIB
NFKB inhibitor beta
total:7
A critical role for CHIP in the aggresome pathway. 2009 to the paper
Santa Cruz NFKBIB antibody was used for Western blotting in order to study the critical role for CHIP in the aggresome pathway. more
NOD1
nucleotide binding oligomerization domain containing 1
NOD2
nucleotide binding oligomerization domain containing 2
total:2
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. 2006 to the paper
Cayman Chemical NOD2-specific rabbit antiserum was used in immunoprecipitation and western blot to measure its expression in primary keratinocytes and transfected HEK293 cells. more
p50
nuclear factor kappa B subunit 1
total:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-p50 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
p65
RELA proto-oncogene, NF-kB subunit
total:146
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Santa Cruz anti-p65 antibody was used to perform immunofluorescence in order to study the role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1
total:5
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 to the paper
Santa Cruz goat anti-Tab1 antibody was used to perform western blotting in order to determine the role of NRAGE in regulating NF-kappaB activity. more
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2
total:2
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TAB2 monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3
Tak1
mitogen-activated protein kinase kinase kinase 7
total:10
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 to the paper
Santa Cruz mouse anti-Tak1 antibody was used to perform western blotting in order to determine the role of NRAGE in regulating NF-kappaB activity. more
TRAF6
TNF receptor associated factor 6
total:17
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TRAF6 (H-274) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more