Signaling by Robo receptor
gene
reagent
sample publication
sample review
abl
ABL proto-oncogene 1, non-receptor tyrosine kinase
total:35
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Calbiochem c-Abl antibody (1:1,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
ABL2
ABL proto-oncogene 2, non-receptor tyrosine kinase
CAP1
cyclase associated actin cytoskeleton regulatory protein 1
total:1
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Abnova mouse anti-CAP1 antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking.
CAP2
cyclase associated actin cytoskeleton regulatory protein 2
cdc42
cell division cycle 42
total:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-Cdc42 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation. more
cdc42
cell division cycle 42
total:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-Cdc42 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation. more
CLASP1
cytoplasmic linker associated protein 1
total:1
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GFP monoclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease.
CLASP1
cytoplasmic linker associated protein 1
total:1
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GFP monoclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease.
PAK1
p21 (RAC1) activated kinase 1
total:29
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Epitomics rabbit monoclonal anti-Pak1 antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
Pak2
p21 (RAC1) activated kinase 2
total:6
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 to the paper
Santa Cruz Biotechnology anti-PAK-2 antibody was used for western blot in order to investigate the role of PAK-2 in the regulation of anticancer drug-induced cell apoptosis. more
PAK3
p21 (RAC1) activated kinase 3
total:1
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 to the paper
Santa Cruz Biotechnology anti-PAK-3 antibody was used for western blot in order to investigate the role of PAK-2 in the regulation of anticancer drug-induced cell apoptosis.
PAK4
p21 (RAC1) activated kinase 4
total:3
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
BD Biosciences monoclonal anti-Pak4 antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
PAK5
p21 (RAC1) activated kinase 5
total:1
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties. 2006 to the paper
EMD Biosciences polyclonal anti-Pak5 antibody was used in human IMR32 cells and in immunocytochemistry to study the role for nucleocytoplasmic shuttling of Pak5 in regulating its antiapoptotic properties.
PFN1
profilin 1
total:4
Self-assembly of filopodia-like structures on supported lipid bilayers. 2010 to the paper
Axxora anti-profilin antibody was used to carry out immunofluorescence assays in order to investigate the mechanism for how filopodia-like structures is self-assembled. more
PFN2
profilin 2
total:1
Absence of gemin5 from SMN complexes in nuclear Cajal bodies. 2007 to the paper
Dr. Glenn E Morris (RJAH Orthopaedic Hospital) monoclonal profilin II antibody (PF2A3) was used in western blot and immunocytochemistry to study the absence of gemin5 from SMN complexes in nuclear Cajal bodies
Rac1
Rac family small GTPase 1
total:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Millipore anti-Rac1 monoclonal antibody (1:1,000) was used to perform immunoblot in order to study the metastasis suppressed by Rho GDP dissociation inhibitor 2 (RhoGDI2) through Rho GTPases. more
Sos
SOS Ras/Rac guanine nucleotide exchange factor 1
total:11
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 to the paper
Santa Cruz rabbit Sos-1 antibody was used in western blot to study the role of Abi-1 in morphogenesis and synapse formation. more
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2
total:1
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis. 2005 to the paper
BD Biosciences anti-SOS-2 antibody was used in western blot to study the role of AIF in nuclear phenotype and DNA degradation during apoptosis
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
total:1
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-srGAP1 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation.
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
total:1
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-srGAP1 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation.
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
VASP
vasodilator stimulated phosphoprotein
total:10
Modulation of Rac1 activity by ADMA/DDAH regulates pulmonary endothelial barrier function. 2009 to the paper
Chemicon International rabbit polyclonal anti-VASP antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the roles of ADMA and DDAH in the regulation of pulmonary endothelial barrier function. more