Signaling by Hippo
gene
reagent
sample publication
sample review
14 3 3 protein beta alpha
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
total:9
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3beta antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
14 3 3 protein epsilon
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
total:5
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Santa Cruz Biotechnology anti-14-3-3epsilon antibody (1:2000) was used in western blot to study the effects of curcumin on the expression of peroxisome proliferator-activated receptor delta (PPARdelta) and related genes in HT-29 cells. more
caspase-3
caspase 3
total:212
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 to the paper
Abcam Caspase-3 antibody was used to perform immunohistochemistry in order to study theeffect of thiabendazole on proliferation and apoptosis of human cells. more
DVL2
dishevelled segment polarity protein 2
total:4
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. 2007 to the paper
Santa Cruz Biotechnology Dvl2 antibody was used in western blot to identify CK1 as additional components of the Wnt-5a-Dvl pathway in dopaminergic cells. more
LATS1
large tumor suppressor kinase 1
total:2
Hippo pathway effector Yap is an ovarian cancer oncogene. 2010 to the paper
Bethyl Laboratories anti-Lats-1 antibody was used in western blot to study the effect of the hippo pathway effector Yap on the progression of ovarian cancer. more
LATS2
large tumor suppressor kinase 2
total:2
A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization. 2006 to the paper
Santa Cruz Biotechnology anti-KPM/Lats2 antibody was used in immunocytochemistry to study the effect of Lats2 on p53 ubiquitination and activation in human U2OS cells. more
MOB1B
MOB kinase activator 1B
total:1
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Abgent anti-Mob1A antibody was used in western blot in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis.
SAV1
salvador family WW domain containing protein 1
total:1
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. 2010 to the paper
Cell Signaling Sav1 antibody was used in western blot to investigate the role of hippo signaling in the regulation of mammalian organ size.
STK3
serine/threonine kinase 3
total:1
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. 2010 to the paper
Cell Signaling Mst2 antibody was used in western blot to investigate the role of hippo signaling in the regulation of mammalian organ size.
STK4
serine/threonine kinase 4
total:1
Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis. 2006 to the paper
Cell Signaling Technology rabbit polyclonal antibodies to Mst1 were used in western blot to detect Mst1 in human 293T and U2OS cell lines.
TJP2
tight junction protein 2
total:3
EspF Interacts with nucleation-promoting factors to recruit junctional proteins into pedestals for pedestal maturation and disruption of paracellular permeability. 2008 to the paper
Zymed Laboratories rabbit polyclonal anti-ZO-2 antibody was used in western blot and immunocytochemistry to study the role for EspF in pedestal maturation and the disruption of paracellular permeability. more
WWTR1
WW domain containing transcription regulator 1
YAP1
Yes1 associated transcriptional regulator
total:3
Hippo pathway effector Yap is an ovarian cancer oncogene. 2010 to the paper
Santa Cruz Biotechnology anti-Yap antibody was used in western blot and immunohistochemistry to study the effect of the hippo pathway effector Yap on the progression of ovarian cancer. more
ZO 1
tight junction protein 1
total:55
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Zymed mouse anti-ZO-1 (1:1,000) antibody was used to perform immunofluorescence in order to study the role for TRAF4, a novel phosphoinositide-binding protein, in modulating tight junctions and promoting cell migration. more