Signaling by FGFR1 mutants
gene
reagent
sample publication
sample review
total:7
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 to the paper
Cell Signaling Technology anti-pY-BCR-ABL antibody was used to carry out western blot analysis in order to investigate the mechanism for Lyn kinase regulating imatinib sensitivity in chronic myelogenous leukemia cells. more
total:3
Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse. 2009 to the paper
Santa Cruz Biotechnology Cux-1 antibody was used in immunohistochemistry in order to demonstrate that the brain tuberous sclerosis complex (TSC) can be caused by the loss of function of Tsc2 in radial glia. more
total:20
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. 2009 to the paper
Chemicon rabbit polyclonal anti-FGF2 antibody was used in western blot to study the role for endothelial-derived FGF2 in the progression of pulmonary hypertension in humans and rodents. more
total:2
HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. 2006 to the paper
R&D Systems goat polyclonal anti-human FGF-1 antibody was used in ELISA to study the HSulf-2 which selectively mobilizes heparin-bound growth factors and chemokines. more
total:2
Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. 2008 to the paper
R&D Systems FGF9 antibody was used in immunohistochemistry at 5 ug/ml in order to study the role of androgen receptor null cells in prostate cancer bone metastases treatment more
total:17
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Biosource International anti-FGFR-1 (pYpY653/654) antibodies were used to perform western blot and ELISA analyses in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
total:1
Daughter centriole elongation is controlled by proteolysis. 2010 to the paper
Proteintech Group rabbit anti-human FGFR1OP antibody was used to perform immunocytochemistry in order to study the role of proteolysis in daughter centriole elongation.
total:6
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Upstate anti-Gab2 polyclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
total:36
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal against Ron antibody was used in western blot in order to demostrate the expression of PAX 5 and the regulation for c-Met transcription in small cell lung cancer. more
total:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-p110alpha was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:43
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Upstate anti-p85 pAb was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:32
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-PLCG1 antibody was used to carry out western blot analysis and immunoprecipitation assays in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:84
T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response. 2010 to the paper
Santa Cruz Biotechnology anti-STAT1 polyclonal antibody was used to perform immunohistochemistry in order to study the transcriptional features of T-cell/histiocyte-rich large B-cell lymphoma. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:51
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Santa Cruz Biotechnology anti-STAT5 antibody was used to perform immunoprecipitation in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers. more
total:23
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 2009 to the paper
Upstate Biotech-Millipore anti-P-STAT5B (Y699) antibody was used in western blot in order to characterize the role of ERBB4 mutations in melanoma. more
total:1
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. 2009 to the paper
Abcam anti-TRIM24 antibody was used to perform western blot in order to study the novel BRAF fusion gene in 7q34 duplication of pediatric low-grade astrocytomas detected by high density SNP-based genotype array analysis.