Signaling by BMP
gene
reagent
sample publication
sample review
ACVR2B
activin A receptor type 2B
total:2
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1. 2005 to the paper
R & D Systems anti-Act-RIIb was used to perform western blot in order to show that in mature human B cells BMP-6 could regulate Smad phosphorylation, Id1 expression, and cell growth. more
BMP2
bone morphogenetic protein 2
total:8
A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. 2008 to the paper
Santa Cruz Biotechnology anti-BMP2 antibody was used in immunohistochemistry to identify these TGFbeta family members in human endometrium, and to determine whether they are involved in human decidualization. more
BMPR1A
bone morphogenetic protein receptor type 1A
total:5
Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin. 2006 to the paper
Santa Cruz Biotechnology anti-BMPR1a antibody was used to perform immunocytochemistry in order to study the regulatory effects of highly expressed bone morphogenetic protein 4(BMP4) and Gremlin toward myogenic progenitor proliferation in human fetal skeletal muscle. more
BMPR1B
bone morphogenetic protein receptor type 1B
total:3
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1. 2005 to the paper
R & D Systems anti-BMP-RIB was used to perform western blot in order to show that in mature human B cells BMP-6 could regulate Smad phosphorylation, Id1 expression, and cell growth. more
BMPR2
bone morphogenetic protein receptor type 2
total:7
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
R&D systems anti-BMPRII antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
NOG
noggin
total:3
Bone morphogenetic protein 9 induces the transcriptome of basal forebrain cholinergic neurons. 2005 to the paper
Regeneron Pharmaceuticals noggin antibody was used in western blot (50 ng/ml) to study gene expression patterns in septal cultures of embryonic day 14 mice and rats grown in the presence or absence of BMP9. more
Smad1
SMAD family member 1
total:28
Transforming growth factor beta promotes neuronal cell fate of mouse cortical and hippocampal progenitors in vitro and in vivo: identification of Nedd9 as an essential signaling component. 2010 to the paper
Santa Cruz Biotechnology mouse anti-Smad1 antibody was used to carry out immunofluorescence assays in order to investigate the role for transforming growth factor beta in regulating neuronal cell development. more
Smad4
SMAD family member 4
total:21
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. 2008 to the paper
Santa Cruz rabbit anti-Smad4(H-552; 1:1,000) antibody was used to perform western blot in order to study the dynamical regulation of TGF-beta signaling during late lung development in the human and mouse. more
SMAD5
SMAD family member 5
total:11
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-Smad5 antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
SMAD6
SMAD family member 6
total:2
Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells. 2008 to the paper
Cell Signaling Technology anti-Smad6 antibody was used in western blot to elucidate the anti-mitogenic effect of a proteasome inhibitor in relation to BMP signalling in colon cancer. more
Smad7
SMAD family member 7
total:12
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. 2010 to the paper
Invitrogen anti-Smad7 was used to perform western blot in order to study the roles of RBBP9 as a tumor-associated serine hydrolase to pancreatic neoplasia more
SMAD9
SMAD family member 9
total:5
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-Smad8 antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
total:3
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-Smurf1 antibody was used to carry out western blot analysis and immunohistochemistry assays in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
total:3
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-Smurf2 antibody was used to carry out western blot analysis and immunohistochemistry assays in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
UBE2D1
ubiquitin conjugating enzyme E2 D1
total:1
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes. 2007 to the paper
Boston Biochem anti-UbcH5 antibody was used to perform immunoprecipitation in order to study the roles of the DET1 during the regulation of the Cul4A activity.
UBE2D3
ubiquitin conjugating enzyme E2 D3
total:1
Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. 2010 to the paper
Abcam anti-UbcH5c antibody was used to perform western blot in order to study the mechanism of A20 action in the inhibition of NF-kappaB signaling.