Signal Transduction
gene
reagent
sample publication
sample review
total:5
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 to the paper
Abgent anti-CKI epsilon was used to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction more
total:9
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3beta antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
total:5
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Santa Cruz Biotechnology anti-14-3-3epsilon antibody (1:2000) was used in western blot to study the effects of curcumin on the expression of peroxisome proliferator-activated receptor delta (PPARdelta) and related genes in HT-29 cells. more
total:6
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3zeta antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
total:38
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. 2011 to the paper
Cell Signaling Technology anti-4E-BP1 and phospho-T37/T46 4E-BP1, phospho-S65 4E-BP1 were used to perform western blot in order to show that how growth factor signaling is inhibited by mTOR through mTOR-regulated phosphoproteome. more
total:8
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Abcam ACTH antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
total:2
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1. 2005 to the paper
R & D Systems anti-Act-RIIb was used to perform western blot in order to show that in mature human B cells BMP-6 could regulate Smad phosphorylation, Id1 expression, and cell growth. more
total:10
S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10. 2009 to the paper
Chemicon ADAM-10 antibody was used for western blot in order to indentify new biomarker of Alzheimer's disease. more
total:4
The disintegrin and metalloproteinase ADAM12 contributes to TGF-beta signaling through interaction with the type II receptor. 2007 to the paper
Nathalie Th ret (Institut National de la Sant et de la Recherche Medicale) anti-ADAM12 Rb 122 was used in western blot and immunoprecipitation to study the role of disintegrin and metalloproteinase ADAM12 in TGF-beta signaling through interaction with the type II receptor more
total:13
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. 2008 to the paper
Santa Cruz Biotechnology anti-TACE antibody was used to perform Western Blot in order to show that TACE has a inhibitory role in EGFR axis in colorectal cancer. more
total:2
Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase. 2005 to the paper
FabGennix isoform-specific anti-adenylate cyclase antibody was used in western blot to study the effedt of interferon-gamma on adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia. more
total:2
Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. 2007 to the paper
Santa Cruz Biotechnology AC2 antibody was used in western blot to demonstrate stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. more
total:3
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Santa Cruz anti-adenylyl cyclase III antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
total:3
Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. 2007 to the paper
Santa Cruz Biotechnology anti-adenylate cyclase antibody was used in western blot to study the role of PDE3B and its interaction with PKB for regulation of specific cAMP pools and signalling pathways by insulin. more
total:4
Accelerated variant of idiopathic pulmonary fibrosis: clinical behavior and gene expression pattern. 2007 to the paper
Chemicon Int rabbit anti-human adenosine 2B receptor (A2BAR) polyclonal antibody was used to perform immunohistochemistry(5 ug/ml) and western blot(2 ug/ml) in order to study the clinical and molecular features of accelerated IPF. more
total:1
Circadian-related heteromerization of adrenergic and dopamine D? receptors modulates melatonin synthesis and release in the pineal gland. 2012 to the paper
Abcam rabbit anti-alpha1 receptor antibody was used to perform immunoprecipitation and immunostaining to study the modulation of the synthesis and release of the melatonin in the pineal gland by the heteromerization of adrenergic and dopamine D₄ receptors.
total:3
Circadian-related heteromerization of adrenergic and dopamine D? receptors modulates melatonin synthesis and release in the pineal gland. 2012 to the paper
Santa Cruz Biotechnology rabbit anti-alpha1 receptor antibody was used to perform immunoprecipitation and immunostaining to study the modulation of the synthesis and release of the melatonin in the pineal gland by the heteromerization of adrenergic and dopamine D₄ receptors. more
total:7
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
Santa Cruz Biotechnology anti-ADRB2 C-tail antibody was used to carry out western blot analysis in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
total:5
Mechanisms responsible for vascular hyporesponsiveness to adrenomedullin after hemorrhage: the central role of adrenomedullin binding protein-1. 2005 to the paper
Accurate Chemical AMBP-1 antibody was used in western blot to study the role of adrenomedullin binding protein-1 in vascular hyporesponsiveness to adrenomedullin after hemorrhage. more
total:4
Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA. 2010 to the paper
Millipore anti-Ago2 antibody was used to carry out immunoprecipitation assays in order to investigate the role for Herpesvirus saimiri Noncoding RNA HSURs in the regulation of host cell microRNAs. more
total:6
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 to the paper
IgG corporation rabbit polyclonal anti-ang II serum was used in immunohistochemistry in order to study the glomerular AGT's expression and its correlation with expression of other RAS components more
total:9
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 to the paper
Santa Cruz rabbit anti-AT1 was used to perform immunohistochemistry in order to show that the expression of ETB and AT1 receptor is upregulated in ischemic heart disease patients. more
total:6
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 to the paper
Santa Cruz rabbit anti-AT2 was used in 1:50 dilution to perform immunohistochemistry in order to show that the expression of ETB and AT1 receptor is upregulated in ischemic heart disease patients. more
total:1
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. 2007 to the paper
Abgent Monoclonal anti-His antibody was used to perform immunoprecipitation in order to investigate the role of human Tim-Tipin complex during the UV-induced intra-S checkpoint.
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:4
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. 2011 to the paper
Cell Signaling Technology anti-phospho-PRAS40 was used to perform western blot in order to show that how growth factor signaling is inhibited by mTOR through mTOR-regulated phosphoproteome. more
total:4
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. 2008 to the paper
Millipore anti-Akt3 was used to perform western blot in order to show that PTEN-null tumors is promoted to autophagy and more sensitive to lysosomotropic agents after Akt inhibition. more
total:1
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Invitrogen rabbit IgG was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models.
total:17
FCHo proteins are nucleators of clathrin-mediated endocytosis. 2010 to the paper
Transduction Laboratories mouse monoclonal anti-AP2A1 antibody was used to carry out western blot analysis in order to investigate the roles for FCHo1 and FCHo2 proteins in clathrin-mediated endocytosis in cell plasma membrane. more
total:14
The ancient drug salicylate directly activates AMP-activated protein kinase. 2012 to the paper
Cell Signalling anti-pAMPK was used to perform western blot in order to show that AMPK could be activated by salicylate directly. more
total:7
Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. 2010 to the paper
Invitrogen anti-ANXA1 andibody was used to perform immnunohistochemistry, western blot and ELISA in order to study the functions of Annexin A1 in the anti-inflammatory and neuroprotective role of microglia. more
total:5
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
Sigma anti-alpha-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. more
total:5
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1/2b antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
total:2
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. 2006 to the paper
BD Biosciences monoclonal anti-AP50 antibody was used in human HeLa cells or HUVECs and in western blot to study the role for clathrin adaptor AP2 in regulating thrombin receptor constitutive internalization and endothelial cell resensitization. more
total:11
A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis. 2009 to the paper
Calbiochem anti-APC was used to perform immunocytochemistry in order to show that MRP protein plays an important role in adherens junction formation and tumorigenesis more
total:1
Apelin mediates the induction of profibrogenic genes in human hepatic stellate cells. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-AP antibody was used to perform immunofluorescence in order to study the involvement of apelin in fibrogenesis during human liver disease.
total:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 to the paper
Abcam polyclonal rabbit anti-apoA-I antibody (1:10,000) was used for western blot in order to investigate the distinct roles of apolipoprotein components in a transgenic mouse model. more
total:1
The expression of intact and mutant human apoAI/CIII/AIV/AV gene cluster in transgenic mice. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal human apoAIV antibody was used in western blot to study the expression of human apoAI/CIII/AIV/AV in transgenic mice
total:2
Serum amyloid P colocalizes with apolipoproteins in human atheroma: functional implications. 2007 to the paper
Calbiochem rabbit polyclonal apoC-II antibody was used in immunohistochemistry to study the colocalization of serum amyloid P with apolipoproteins in human atheroma more
total:19
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Calbiochem anti-ApoE antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:14
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Abcam anti-ApoB100 antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:81
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Chemicon anti-APP was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:1
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 to the paper
ABGENT anti-GRAF was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis.
total:3
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 to the paper
BD Biosciences anti-p190RhoGAP was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis. more
total:3
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Transduction Laboratories p115 antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
total:3
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Spring Bioscience anti-D4-GDI polyclonal antibody (1:1,000) was used to perform immunoblot in order to study the Rho GDP dissociation inhibitor 2 (RhoGDI2) suppressed metastasis through Rho GTPases. more
total:1
Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT. 2005 to the paper
Proteintech Group rabbit anti-GEFT antibody was used to carry out immunohistochemistry assay and western blot analysis in order to characterize the roles for Rho-GEFs in modulating skeletal muscle regeneration, myogenesis, and adipogenesis.
total:1
GM130-dependent control of Cdc42 activity at the Golgi regulates centrosome organization. 2009 to the paper
Santa Cruz Biotechnology anti-beta-PIX antibody was used in western blot to study the role for GM130-dependent control of Cdc42 activity at the golgi in regulating centrosome organization
total:7
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 to the paper
Santa Cruz Biotechnology beta-arrestin1/2 rabbit polyclonal antibody (21-B1) was used to perform western blot in order to clarify that the arrestin-2/STAM-1 complex modulates CXCR4 lysosomal sorting by ubiquitination of HRS. more
total:3
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. 2006 to the paper
Affinity BioReagents polyclonal anti-beta arrestin 2 antibody was used in human embryonic kidney (HEK) 293 cells and in western blot to study the role of G protein-coupled receptor kinase site serine cluster in beta-arrestin-dependent beta2AR internalization and desensitization. more
total:2
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 to the paper
Bethyl Laboratories anti-Ash2L antibody was used for coimmunoprecipitation in order to illustrate the role of c-Myb in MLL-associated leukemogenesis. more
total:6
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology murine monoclonal anti-ATF-1 antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:1
Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization. 2010 to the paper
BioVision rabbit anti-A1 polyclonal antibody (1/400) was used to perform western blot and immunoprecipitation in order to study the function of cancer cell lines mitochondria in exploring the mechanisms of BH3 peptides and ABT-737 induced mitochondrial membrane permeabilization.
total:1
Regulation of Spo12 phosphorylation and its essential role in the FEAR network. 2009 to the paper
Molecular Probes mouse anti-Vph1 antibody (1:2000 dilution) was used to perform western blot in order to investigate the regulation of S118 phosphorylation of Spo12 and its essential role for FEAR network function.
total:1
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
Abcam anti-ATP6V0D1 was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation.
total:1
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
GeneTex anti-ATP6V1A was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation.
total:1
Topology of the yeast fatty acid transport protein Fat1p: mechanistic implications for functional domains on the cytosolic surface of the plasma membrane. 2007 to the paper
Molecular Probes mouse anti-Vma2p antibody was used in western blot to define the role of Fat1p in the transport of exogenous fatty acids.
total:1
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
Santa Cruz anti-ATP6V1D was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation.
total:1
Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney. 2007 to the paper
Santa Cruz Biotechnology anti-human vacuolar type H+-ATPase B1/2 (V-ATPase) antibody was used in immunohistochemistry to localize broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney
total:1
Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration. 2007 to the paper
Santa Cruz Biotechnology type I ADH antibody was used in western blot to study the role of alcohol and aldehyde dehydrogenase activities in rat liver regeneration.
total:1
Prolactin activates mitogen-activated protein kinase signaling and corticotropin releasing hormone transcription in rat hypothalamic neurons. 2009 to the paper
Aachen VP (vasopressin) monoclonal antibody was used in immunohistochemistry in order to investigate the mechanism for the prolactin-mediated hypothalamic pituitary adrenal axis inhibition during lactation in hypothalamic neurons.
total:1
Inherent sexually dimorphic expression of hepatic CYP2C12 correlated with repressed activation of growth hormone-regulated signal transduction in male rats. 2008 to the paper
Cell Signaling Technology phospho-Erk1 and Erk2 (phospho-p42/p44 MAPK) antibody was used in western blot in order to demonstrate that continuous GH induces CYP2C12 expression by activating Erk1 and Erk2 via the GHR
total:2
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 to the paper
Zymed anti-axin antibody was used in western blot in order to show that Wnt/catenin signaling, osteoblast function, and bone formation can be negatively regulated by the N-cadherin-axin-LRP5 interaction. more
total:2
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 to the paper
Cell Signaling anti-Axin2 antibody was used to perform western blot in order to study the roles of the fragile X mental retardation protein during the regulations of the proliferation and differentiation of adult neural stem/progenitor cells. more
total:8
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-Braf antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Cell Signaling Technology, anti-BAD monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:7
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 to the paper
Cell Signaling Technology anti-pY-BCR-ABL antibody was used to carry out western blot analysis in order to investigate the mechanism for Lyn kinase regulating imatinib sensitivity in chronic myelogenous leukemia cells. more
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
total:2
ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx. 2005 to the paper
R&D Systems goat anti-human BTC ectodomain (Asp32 Tyr111) antibody was used in immunoprecipitation, biotinylated goat anti-human BTC ectodomain in western blot and mouse anti-human BTC ectodomain antibody in ELISA to study the role for ADAM10 to mediate ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate (APMA) and extracellular calcium influx. more
total:31
Control of cellular Bcl-xL levels by deamidation-regulated degradation. 2013 to the paper
Calbiochem anti-Bim antibody was used to perform immunoprecipitation in order to investigate the regulatory effect of deamidation on Bcl-xL degradation. more
total:8
A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. 2008 to the paper
Santa Cruz Biotechnology anti-BMP2 antibody was used in immunohistochemistry to identify these TGFbeta family members in human endometrium, and to determine whether they are involved in human decidualization. more
total:5
Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin. 2006 to the paper
Santa Cruz Biotechnology anti-BMPR1a antibody was used to perform immunocytochemistry in order to study the regulatory effects of highly expressed bone morphogenetic protein 4(BMP4) and Gremlin toward myogenic progenitor proliferation in human fetal skeletal muscle. more
total:3
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1. 2005 to the paper
R & D Systems anti-BMP-RIB was used to perform western blot in order to show that in mature human B cells BMP-6 could regulate Smad phosphorylation, Id1 expression, and cell growth. more
total:7
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
R&D systems anti-BMPRII antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
total:13
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 to the paper
Abcam anti-SMARCB4 antibody was used to perform western blot in order to study the role of SWI/SNF in regulation of the latent HIV LTR before and after transcriptional activation. more
total:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Zymed Laboratories mouse anti-beta TRCP antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
total:42
Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. 2012 to the paper
NeoMarkers mouse anti-human CD117 monoclonal antibody was used to perform immunohistochemistry in order to analyze the cellular origin of adult functional blood vessels. more
total:235
Regulation of early adipose commitment by Zfp521. 2012 to the paper
Santa Cruz Biotechnology anti-MYC antibody was used to carry out western blot and immunoprecipitation assays in order to investigate the regulatory role of Zfp521 in determining the switch between the adipogenic and osteogenic lineages. more
total:12
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. 2011 to the paper
AbD serotec goat-anti-Human-C3 was used to perform ELISA in order to show that HIV glycan coat could be recognized by PGT antibody to neutralize HIV. more
total:1
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. 2005 to the paper
Quidel mouse monoclonal antibody against C5b-9 was used in ELISA to study the association of the extracellular matrix and inflammation
total:1
Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis. 2009 to the paper
Epitomics MO25 rabbit monoclonal antibody was used for Western blotting in order to investigate the effect of LKB1 on nucleocytoplasmic transport.
total:6
Role of FNA cytology and immunochemistry in the diagnosis and management of medullary thyroid carcinoma: report of six cases and review of the literature. 2007 to the paper
Dako calcitonin antibody (1:200) was used in immunohistochemistry to study the role of FNA cytology and immunochemistry in the diagnosis and management of medullary thyroid carcinoma. more
total:6
Role of FNA cytology and immunochemistry in the diagnosis and management of medullary thyroid carcinoma: report of six cases and review of the literature. 2007 to the paper
Dako calcitonin antibody (1:200) was used in immunohistochemistry to study the role of FNA cytology and immunochemistry in the diagnosis and management of medullary thyroid carcinoma. more
total:4
ASB4 is a hydroxylation substrate of FIH and promotes vascular differentiation via an oxygen-dependent mechanism. 2007 to the paper
Novus anti-FIH was used in western blot to investigate the interaction between ASB4 and FIH in human HEK-293T cells. more
total:13
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 to the paper
Affinity Bioreagents anti-phospho-CaMKII antibody was used for western blot in order to investigate the role of CaMKII in the regulation of pressure overload-induced cardiac hypertrophy to heart failure in mice. more
total:3
Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation. 2005 to the paper
Transduction Laboratories monoclonal anti-CaMKIV antibody was used in western blot and immunocytochemistry to study the presence of CaMKIV in mammalian sperm and its role in the regulation of human sperm motility. more
total:9
Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI. 2008 to the paper
Santa Cruz Caspase-2 antibody was used in western blot in order to analyze changes in a subproteome of ~800 proteins in the promyelocytic leukemia cell line HL-60 upon treatment with the proteasome inhibitor PSI more
total:212
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 to the paper
Abcam Caspase-3 antibody was used to perform immunohistochemistry in order to study theeffect of thiabendazole on proliferation and apoptosis of human cells. more
total:75
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-caspase-9 antibody was used to perform immunocytochemistry in order to study the protective autophagy involved in trail resistance of apoptosis-defective tumor cells. more
total:6
Cannabinoid CB? receptor is downregulated in clear cell renal cell carcinoma. 2010 to the paper
Cayman Chemical anti-CB2 polyclonal antibody was used to perform western blot and immunohistochemistry in order to study the downregulation of cannabinoid receptor CB1 in clear cell renal carcinoma. more
total:13
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 to the paper
Cell Signaling Technology anti-pY774-c-Cbl antibody was used to carry out western blot analysis in order to investigate the mechanism for Lyn kinase regulating imatinib sensitivity in chronic myelogenous leukemia cells. more
total:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 to the paper
Santa Cruz Biotechnology anti-CBP antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathway more
total:1
Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates Up-regulation of CCL20 and the migration of regulatory T cells. 2008 to the paper
R&D Systems CCL20 antibdoy (1:100) was used in immunohistochemistry in order to study roles of EBNA1 in the escape of EBV-infected HL cells from the virus-specific CTL response
total:5
Internalizing antibodies to the C-type lectins, L-SIGN and DC-SIGN, inhibit viral glycoprotein binding and deliver antigen to human dendritic cells for the induction of T cell responses. 2006 to the paper
Pierce anti-ECL antibody was used in western blot to study the role of DC delivering antigen to T cell. more
total:1
The role of CCL22/macrophage-derived chemokine in allergic rhinitis. 2007 to the paper
Peprotech anti-human CCL22/MDC rabbit polyclonal antibody was used in immunohistochemistry to study the role of CCL22/macrophage-derived chemokine in allergic rhinitis.
total:5
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes. 2008 to the paper
Santa Cruz anti-cyclin T1 antibody was used to perform western blot in order to study the association between ING4 and the activity of NF-kappa B molecules bound with target gene promoters. more
total:3
A key role for CC chemokine receptor 1 in T-cell-mediated respiratory inflammation. 2008 to the paper
Capralogics rabbit anti-human CCR1 antibody was used in flow cytometry at a dilution of 1:200 to stduy the role for CC chemokine receptor 1 in T-cell-mediated respiratory inflammation. more
total:9
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
R&D systems anti-CCR2 antibody (1:100) was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
total:28
Effects of ferumoxides-protamine sulfate labeling on immunomodulatory characteristics of macrophage-like THP-1 cells. 2008 to the paper
Biolegend FITC conjugated mouse anti-human CD195 IgG2a was used in flow cytometry in order to demonstrate that endocytosed FePro nanoparticles did not significantly affect immunological properties of THP-1 cells more
total:5
CC chemokine receptor 6 expression by B lymphocytes is essential for the development of isolated lymphoid follicles. 2007 to the paper
R&D Systems rat anti-mouse CCR6 antibody was used in flow cytometry to study the role for CCR6 in the development of isolated lymphoid follicles (ILFs). more
total:9
Role of Twist in head and neck carcinoma with lymph node metastasis. 2008 to the paper
R&D Systems anti-CCR7 monoclonal antibody was used to perform immunohistochemistry in order to study the role of twist in metastasis of head and neck carcinoma. more
total:3
Autocrine and paracrine promotion of cell survival and virus replication by human herpesvirus 8 chemokines. 2008 to the paper
Epitomics anti-CCR8 antibody was used in western blot to study the effect of human herpesvirus 8 chemokines on endothelial survival and virus replication. more
total:1
CCL25-CCR9 interaction modulates ovarian cancer cell migration, metalloproteinase expression, and invasion. 2010 to the paper
R&D Systems PE-conjugated mouse anti-human CCR9 (clone 112509) antibody was used to perform flow cytometry in order to study the interactions between CCL25 and CCR9 in ovarian carcinoma cell migration and invasion.
total:62
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Becton Dickinson anti-CD19 PE was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
total:11
TRAF6 is required for generation of the B-1a B cell compartment as well as T cell-dependent and -independent humoral immune responses. 2009 to the paper
BD Pharmingen anti-CD23 antibody was used in flow cytometry in order to study the role for TRAF6 in T cell-dependent and T cell-independent humoral immune responses. more
total:25
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD28 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
total:13
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD41 was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:14
The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor alpha expression in the synovium. 2008 to the paper
Serotec monoclonal anti-CD55 antibody (67) was used in immunohistochemistry to determine whether the heterogeneous clinical response to tumour necrosis factor (TNF) alpha blocking therapy in rheumatoid arthritis (RA) can be predicted by TNFalpha expression in the synovium before initiation of treatment. more
total:24
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Beckman anti-CD80 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Beckman anti-CD86 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:2
Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctions. 2010 to the paper
Imgenex rabbit polyclonal CD97 antibody was used in western blot in order to investigate the function of CD97 in intestinal epithelial cells. more
total:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk1 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:5
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import. 2007 to the paper
Affinity BioReagents anti-Cdc37 antibody was used in western blot in order to investigate the functions of Hsp40-related J-domain proteins DJA1, DJA2, and DJA4 during mitochondrial import. more
total:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-Cdc42 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation. more
total:8
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 to the paper
Santa Cruz Biotechnology anti-Cdk5 (SC-173), Cdk5-pTyr-15 (SC-12918), and Cdk5-pSer-159 (SC-12919) antibodies were used to perform western blot in order to investigate the molecular mechanisms underlying CRMP2 function in CXCL12-induced T lymphocyte migration. more
total:5
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK8 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:11
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK9 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:1
Cyclin K and cyclin D1b are oncogenic in myeloma cells. 2010 to the paper
Santa Cruz anti-p15 was used to perform western blot in order to show the role of cyclin K and cyclin D1b in multiple myeloma.
total:11
In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis. 2009 to the paper
Abcam rabbit anti-CHIP was used to perform western blot in order to show that enhancing CHIP activity is good for therapy for SCA3 or other polyQ diseases more
total:59
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 to the paper
Santa Cruz anti-Chk1 monoclonal antibody was used to perform western blot in order to study the interactions of ATR and ATRIP in gene expression and production of virus during HSV-1 infection. more
total:1
Novel regional and developmental NMDA receptor expression patterns uncovered in NR2C subunit-beta-galactosidase knock-in mice. 2007 to the paper
Chemicon International polyclonal cholecystokinin antibody was used in immunohistochemistry to study novel functions of NR2C-containing NMDA receptors.
total:3
M(1) and M(2) muscarinic acetylcholine receptor subtypes mediate Ca(2+) channel current inhibition in rat sympathetic stellate ganglion neurons. 2006 to the paper
Chemicon International rabbit anti-M1 antibody (1:200) was used in immunocytochemistry to study the role of M (1) and M (2) muscarinic acetylcholine receptor subtypes in mediating Ca (2+) channel current inhibition in rat sympathetic stellate ganglion neurons. more
total:5
M(1) and M(2) muscarinic acetylcholine receptor subtypes mediate Ca(2+) channel current inhibition in rat sympathetic stellate ganglion neurons. 2006 to the paper
Abcam rabbit anti-M2 antibody (1:200) was used in immunocytochemistry to study the role of M (1) and M (2) muscarinic acetylcholine receptor subtypes in mediating Ca (2+) channel current inhibition in rat sympathetic stellate ganglion neurons. more
total:28
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 to the paper
Millipore rabbit anti-Clathrin antibody was used to perform immunoelectron microscopy in order to investigate the mechanism of Golgi-mediated protein traffic. more
total:5
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Sigma-Aldrich monoclonal anti-clathrin light chain antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
total:4
Cannabinoid CB? receptor is downregulated in clear cell renal cell carcinoma. 2010 to the paper
ABR Affinity BioReagents anti-CB1 polyclonal antibody was used to perform western blot and immunohistochemistry in order to study the downregulation of cannabinoid receptor CB1 in clear cell renal carcinoma. more
total:9
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. 2010 to the paper
Abcam anti Col IV antibody was used to perform immunohistochemistry in order to study the function of the astrocytic antigen aquaporin 4 (AQP-4) in inflammatory demyelinating diseases. more
total:5
Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. 2005 to the paper
Santa Cruz Biotechnology goat anti-alpha3 antibody was used in western blot to study the effect of activation of vascular endothelial growth factor receptor 3 on endothelial function and infection. more
total:2
ELR-negative CXC chemokine CXCL11 (IP-9/I-TAC) facilitates dermal and epidermal maturation during wound repair. 2008 to the paper
Abcam rabbit polyclonal collagen IV antibody was used in immunohistochemistry in order to study the role of IP-10 and IP-9 in epidermal maturation during wound repair more
total:2
The extracellular matrix glycoprotein elastin microfibril interface located protein 2: a dual role in the tumor microenvironment. 2010 to the paper
Santa Cruz Biotechnology anti-type I collagen antibody was used in western blot in order to investigate the function of the 90-amino acid residue fragment of elastin microfibril interface located protein 2 (EMILIN2) in the tumor microenvironment. more
total:2
Alteration of medial-edge epithelium cell adhesion in two Tgf-beta3 null mouse strains. 2008 to the paper
Developmental Studies Hybridoma Bank 1:50 monoclonal mouse IgG anti-sheep collagen IX antibody was used in immunohistochemistry in order to study the role of growth factor TGF-b3 in palatal shelf adhesion more
total:58
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB1 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:4
Corticotropin-releasing hormone, its binding protein and receptors in human cervical tissue at preterm and term labor in comparison to non-pregnant state. 2006 to the paper
Santa Cruz Biotechnology rabbit polyclonal antibody against CRH was used in immunohistochemistry to detect the localization of CRH in human cervix. more
total:6
Regulation of corticotropin-releasing hormone receptor-2 expression in human cord blood-derived cultured mast cells. 2005 to the paper
Santa Cruz Biotechnology polyclonal goat anti-human/mouse/rat CRH-R1 antibody (V-14 sc-12381) was used in immunocytochemistry to study the expression of CRH-R1 and CRH-R2 n human cord blood-derived cultured mast cells. more
total:3
Evidence for the presence of the type 2 corticotropin releasing factor receptor in the rodent cerebellum. 2006 to the paper
Santa Cruz Biotechnology CRF-RII antibody was used in western blot and immunohistochemistry to demonstrate that the CRF family of peptides modulates cerebellar output by binding to multiple CRF receptors. more
total:14
Focal adhesion components are essential for mammalian cell cytokinesis. 2008 to the paper
BD Transduction Laboratories CrkI/II antibody was used to perform western blot in order to study the function of focal adhesion components in mammalian cell cytokinesis. more
total:13
Chemical rescue of a mutant enzyme in living cells. 2006 to the paper
Santa Cruz Biotechnology anti-CrkL antibody was used in western blot to study the protein tyrosine kinase Src R388A mutant rescued in live cells with the use of the small molecule imidazole. more
total:1
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. 2009 to the paper
Miltenyi Biotec anti-CRTH2-PE antibody was used to carry out flow cytometry analysis in order to investigate the mechanism for IL-33 in promoting allergic inflammation.
total:7
Leukocyte-associated Ig-like receptor-1 has SH2 domain-containing phosphatase-independent function and recruits C-terminal Src kinase. 2006 to the paper
Santa Cruz anti-Csk antibody was used in immnoprecipitation to study the role of leukocyte-associated Ig-like receptor-1. more
total:5
Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy. 2009 to the paper
Bethyl anti-CSN2 was used in 1:1000 dilution to perform western blot in order to show that CSN plays an important role for cell autophagy in K562 cells. more
total:5
Protein kinase CK1alpha regulates mRNA binding by heterogeneous nuclear ribonucleoprotein C in response to physiologic levels of hydrogen peroxide. 2005 to the paper
Santa Cruz Biotechnology Inc. anti-CK1alpha antibody was used in immunoprecipitation to study the role of protein kinase CK1alpha for the regulation of RNA binding activity of heterogeneous nuclear ribonucleoprotein C (hnRNP-C). more
total:9
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 to the paper
Santa-Cruz Biotechnology anti-CK2 alpha antibody was used to carry out western blot analysis in order to investigate the role for NF-kB transcription factor in the interleukin-1 induced expression of C/EBP delta and APP genes. more
total:4
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 to the paper
Santa-Cruz Biotechnology anti-CK2 alpha' antibody was used to carry out western blot analysis in order to investigate the role for NF-kB transcription factor in the interleukin-1 induced expression of C/EBP delta and APP genes. more
total:2
CK2beta is expressed in endometrial carcinoma and has a role in apoptosis resistance and cell proliferation. 2009 to the paper
Santa Cruz anti-CK2B antibody was used to perform western blot and immunohistochemistry in order to show the role of CK2B in apoptosis resistance and cell proliferation in endometrial carcinoma. more
total:4
Loss of full length CtBP1 expression enhances the invasive potential of human melanoma. 2009 to the paper
Transduction Lab anti-CtBP1 was used as a probe in western blot in order to prove that the loss of full length CtBP1 expression can induce human melanoma more
total:1
Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes. 2005 to the paper
Alpha Diagnostic International rabbit anti-human C-terminal modulator protein (CTMP) antibody was used in western blot to study the effect of the interaction between histone deacetylase inhibitors and protein phosphatase 1 complexes on Akt in human U87MG cells.
total:12
Mediator acts upstream of the transcriptional activator Gal4. 2012 to the paper
Abcam anti-Cul1 mouse monoclonal antibody was used to perform immunoprecipitation in order to study how the Mediator initiated Gal4 transcription. more
total:4
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
Santa Cruz Biotechnology anti-Cul3 antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:3
Selective human endothelial cell activation by chemokines as a guide to cell homing. 2009 to the paper
EBioscience anti-chemokine (C-X3-C motif) receptor 1 rabbit IgG was used for flow cytometry in order to demonstrate that chemokines could activate human endothelial cell selectively as a guide to cell homing. more
total:7
Expression of CD74, the receptor for macrophage migration inhibitory factor, in non-small cell lung cancer. 2009 to the paper
R&D Systems anti-human CXCL1/GRO-alpha antibody was used in ELISA to demonstrate whether the expression of CD74 is associated with the angiogenic activity and level of CXC chemokine expression in human specimens of non-small cell lung cancer. more
total:12
Villitis of unknown etiology is associated with a distinct pattern of chemokine up-regulation in the feto-maternal and placental compartments: implications for conjoint maternal allograft rejection and maternal anti-fetal graft-versus-host disease. 2009 to the paper
R&D Systems anti-CXCL10 antibody was used for immunocytochemistry in order to show the placental transcriptome of VUE and identify VUE combines maternal allograft rejection and maternal antifetal graft-vs-host disease. more
total:8
PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts. 2009 to the paper
Abcam rabbit polyclonal anti-SDF1 alpha (alias CXCL12) antibody was used in western blot in order to demonstrate that PTCH1+/- genotype of healthy NBCCS fibroblasts is associated with basal cell carcinoma (BCC). more
total:2
Villitis of unknown etiology is associated with a distinct pattern of chemokine up-regulation in the feto-maternal and placental compartments: implications for conjoint maternal allograft rejection and maternal anti-fetal graft-versus-host disease. 2009 to the paper
Proteintech Group anti-CXCL13 antibody was used for immunocytochemistry in order to show the placental transcriptome of VUE and identify VUE combines maternal allograft rejection and maternal antifetal graft-vs-host disease. more
total:2
EPHB4 regulates chemokine-evoked trophoblast responses: a mechanism for incorporating the human placenta into the maternal circulation. 2005 to the paper
R&D Systems goat CXCL16 polyclonal antibody was used in immunohistochemistry to study chemokine-evoked trophoblast responses more
total:2
Expression of CD74, the receptor for macrophage migration inhibitory factor, in non-small cell lung cancer. 2009 to the paper
PeproTech Inc. anti-CXCL3/GRO-gamma antibody was used in ELISA to demonstrate whether the expression of CD74 is associated with the angiogenic activity and level of CXC chemokine expression in human specimens of non-small cell lung cancer. more
total:3
Expression of CD74, the receptor for macrophage migration inhibitory factor, in non-small cell lung cancer. 2009 to the paper
R&D Systems anti-human CXCL5/ENA-78 antibody was used in ELISA to demonstrate whether the expression of CD74 is associated with the angiogenic activity and level of CXC chemokine expression in human specimens of non-small cell lung cancer. more
total:1
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer. 2008 to the paper
Biocare Medical anti-Pan-CKa(Lu-5) antibody was used to perform immunohistochemistry in order to study the expression of cytokeratin 7 and 19 are related with genomic stability and favorable prognosis in clear cell renal cell cancer.
total:6
Villitis of unknown etiology is associated with a distinct pattern of chemokine up-regulation in the feto-maternal and placental compartments: implications for conjoint maternal allograft rejection and maternal anti-fetal graft-versus-host disease. 2009 to the paper
R&D Systems anti-CXCL9 antibody was used for immunocytochemistry in order to show the placental transcriptome of VUE and identify VUE combines maternal allograft rejection and maternal antifetal graft-vs-host disease. more
total:7
Short-term heat exposure inhibits inflammation by abrogating recruitment of and nuclear factor-{kappa}B activation in neutrophils exposed to chemotactic cytokines. 2008 to the paper
Santa Cruz IL-8-receptor antibody was used in western blot in order to test the hypothesis that exposure of mice to fever-like temperatures abrogates neutrophil recruitment and NF-kappaB activation in a mouse model of skin inflammation more
total:9
The role of the chemokines MCP-1, GRO-alpha, IL-8 and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques. 2008 to the paper
R&D Systems CXCR2 IgG2a antbody was used to inhibit cell adhesion in order to study the role of the chemokines MCP-1, GRO-alpha, IL-8, and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques more
total:11
A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells. 2008 to the paper
R&D Systems monoclonal anti-CXCR3 was used to perform blocking or activating experiments in order to show that a computational-based peptidomics can be used to identify peptides inhibiting the proliferation and migration of endothelial cells systematically. more
total:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CXCR4 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:4
Striking alteration of some populations of T/B cells in systemic lupus erythematosus: relationship to expression of CD62L or some chemokine receptors. 2008 to the paper
R&D phycoerythrin(PE)-conjugated anti-CXCR5 (51505) antibody was used to perform flow cytometry and immunocytochemistry in order to study the relationship between striking alteration of some populations of T/B cells and expression of CD62L or some chemokine receptors in patients with systemic lupus erythematosus. more
total:2
Role of Twist in head and neck carcinoma with lymph node metastasis. 2008 to the paper
R&D Systems anti-CXCR6 monoclonal antibody was used to perform immunohistochemistry in order to study the role of twist in metastasis of head and neck carcinoma. more
total:123
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-Cyclin D1 antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:1
Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C. 2005 to the paper
BD Biosciences mouse monoclonal antibody to DGK theta theta was used in western blot to provide evidence in vitro and in vivo for a major role for PKCepsilon and/or PKCeta activation in the regulation of DGKdelta translocation to the plasma membrane.
total:5
Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer. 2008 to the paper
Abcam goat anti-human Dkk-1 anti-body was used to perform immunohistochemistry in order to investigate the expression alteration of dickkopfs (Dkks) and kremen2 (Krm2) in gastrointestinal cancer. more
total:2
EWS/ETS regulates the expression of the Dickkopf family in Ewing family tumor cells. 2009 to the paper
Biovision anti-DKK2 antibody was used to detect secreted DKK2 in western blot in order to demonstrate that the expression of the dickkopf family in Ewing family tumor cells were affected by EWS/ETS. more
total:5
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
For exploring the effect of DLC1 on angiogenesis, BD Biosciences anti-DLC1 monoclonal antibody was used for performing immunohistochemistry. more
total:2
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors. 2005 to the paper
Santa Cruz Biotechnology polyclonal anti-Delta1 antibody (sc-8155) was used in immunohistochemistry to study the effect of Delta1 versus Jagged1 on T-cell progenitors at specific developmental stages in sections from human thymic tissue. more
total:1
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. 2007 to the paper
I. B. Lobov (Regeneron Pharmaceuticals) Dll4 antibody was used in immunohistochemistry to study the role of Dll4 during vascular growth and differentiation.
total:6
Mechanisms of Chlamydia trachomatis entry into nonphagocytic cells. 2007 to the paper
BD Biosciences anti-dynamin-2 antibody was used to carry out immunofluorescence assays in order to investigate the mechanism of entry for Chlamydia trachomatis into nonphagocytic cells. more
total:2
Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef. 2007 to the paper
Affinity BioReagents anti-Dyn3 antibody was used in western blot in order to investigate the mechanism of how dynamin 2 (a binding partner of Nef) enhances the infectivity of HIV-1. more
total:3
Chemical rescue of a mutant enzyme in living cells. 2006 to the paper
Santa Cruz Biotechnology anti-Dok-1 antibody was used in western blot to study the protein tyrosine kinase Src R388A mutant rescued in live cells with the use of the small molecule imidazole. more
total:7
D1 and D2 dopamine receptor expression is regulated by direct interaction with the chaperone protein calnexin. 2007 to the paper
Chemicon rabbit polyclonal anti-D2L/S (catalog number AB5084P) antibody was used in western blot to study the regulation of D1 and D2 dopamine receptor expression by direct interaction with the chaperone protein calnexin more
total:2
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 to the paper
Zymed Laboratories monoclonal anti-D3R antibody was used to perform western blot in order to study the important role of GRK4 in D3 receptor's signaling in human proximal tubule cells. more
total:1
Circadian-related heteromerization of adrenergic and dopamine D? receptors modulates melatonin synthesis and release in the pineal gland. 2012 to the paper
Santa Cruz Biotechnology goat anti-D4 receptor antibody was used to perform immunoprecipitation and immunostaining to study the modulation of the synthesis and release of the melatonin in the pineal gland by the heteromerization of adrenergic and dopamine D₄ receptors.
total:3
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. 2009 to the paper
Santa Cruz anti-DUSP4 antibody was used for western blot in order to investigate the role of BRAF in the regulation of RAF-MEK signaling pathway. more
total:6
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-MKP3 antibody was used to perform flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:2
Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. 2009 to the paper
Santa Cruz Biotechnology anti-Dvl antibody was used in immunocytochemistry to study the role for bone morphogenetic protein 2 in inducing pulmonary angiogenesis and its mechanism. more
total:4
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. 2007 to the paper
Santa Cruz Biotechnology Dvl2 antibody was used in western blot to identify CK1 as additional components of the Wnt-5a-Dvl pathway in dopaminergic cells. more
total:3
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. 2007 to the paper
Santa Cruz Biotechnology Dvl3 antibody was used in western blot to identify CK1 as additional components of the Wnt-5a-Dvl pathway in dopaminergic cells. more
total:15
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Santa Cruz Biotechnology monoclonal anti-dynamin 1 antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
total:37
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Santa Cruz E2F1 antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:11
Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor. 2007 to the paper
Santa Cruz anti-E2F4 was used to perform ChIP assays in order to show that the evolutionarily conserved gene targets of E2F4 play important roles for cell cycle. more
total:2
CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase. 2009 to the paper
Santa Cruz Biotechnology anti-Ect2 antibody was used in western blot in order to study the reguation of the expression of Ect2, MgcRacGAP, and MKLP1 during cell cycle progression more
total:6
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 to the paper
Santa Cruz goat anti-ETA was used in 1:50 dilution to perform immunohistochemistry in order to show that the expression of ETB and AT1 receptor is upregulated in ischemic heart disease patients. more
total:10
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 to the paper
IBL rabbit anti-ETB was used in 1:400 dilution to perform immunohistochemistry in order to show that the expression of ETB and AT1 receptor is upregulated in ischemic heart disease patients. more
total:9
Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-EGF antibody was used in immunohistochemistry to study whether the expression of tyrosine kinase growth factor receptors is constant or varies between and within individual colon cancer neoplasms. more
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:4
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. 2010 to the paper
Cell Signaling Technology anti-phospho-eIF4B antibody was used to carry out western blot analysis in order to investigate the precise contribution of 4E-BPs to mTORC1 signaling. more
total:37
Control of translation and miRNA-dependent repression by a novel poly(A) binding protein, hnRNP-Q. 2013 to the paper
BD BioSciences anti-eIF4E antibody was used to perform western blot in order to check the protein levels when hnRNP-Q was knocked down. more
total:5
Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. 2010 to the paper
Santa Cruz Biotechnology anti-EIF4G antibody was used to perform immunocytochemistry in order to study the interaction between TDP-43 and proteins that regulate RNA metabolism. more
total:13
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz monoclonal anti-p-ELK1 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:3
Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity. 2010 to the paper
Santa Cruz Biotechnology anti-F4/80 antibody was used to carry out immunohistochemistry assays in order to investigate the role for Sfrp5 as anti-inflammatory adipokine in the modulation of metabolic dysfunction in obesity. more
total:9
Expression of endothelial nitric oxide synthase and endothelin-1 in skin tissue from amputated limbs of patients with complex regional pain syndrome. 2008 to the paper
R&D systems rat anti-human ET-1 antibody (3G10) was used in immunohistochemistry to examine the distribution of eNOS and ET-1 in relation to vascular density represented by the endothelial marker CD31-immunoreactivity in skin tissue from amputated limbs of patients with CRPS. more
total:4
Elevated serum monocyte chemoattractant protein-4 and chronic inflammation in overweight subjects. 2006 to the paper
R&D Systems anti-eotaxin antibody (which was in ELISA kit) was used in serum from human and in ELISA to study the correlation of elevated serum monocyte chemoattractant protein-4 and chronic inflammation with obesity. more
total:4
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Cayman Chemicals anti-EP1 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:3
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Cayman Chemicals anti-EP3 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:9
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. 2008 to the paper
Abcam murine monoclonal anti-PTGER4 antibody was used to perform flow cytometric analysis in order to study the important role of CD30 signaling in Hodgkin's and anaplastic large cell lymphoma (ALCL) cell lines. more
total:2
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 to the paper
Epitomics anti-Epsin1 antibody was used to perform western blot in order to study the roles of the lipid raft-dependent Fc secre tRI ubiquitination in the regulation of receptor endocytosis. more
total:3
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 to the paper
Santa Cruz anti-Eps15 antibody was used to perform western blot in order to study the roles of the lipid raft-dependent Fc secre tRI ubiquitination in the regulation of receptor endocytosis. more
total:2
A requirement for epsin in mitotic membrane and spindle organization. 2009 to the paper
Epitomics rabbit monoclonal anti-Eps15R antibody was used for western blot in order to show that epsin is essential to regulate mitotic membrane morphology and spindle integrity. more
total:112
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-ERa antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:1
KIS protects against adverse vascular remodeling by opposing stathmin-mediated VSMC migration in mice. 2008 to the paper
BD Biosciences goat anti-LAP2 antibody (1:200) was used to perform western blot in order to study the KIS opposed stathmin-mediating VSMC migration.
total:18
Activation of Stat3 by heregulin/ErbB-2 through the co-option of progesterone receptor signaling drives breast cancer growth. 2009 to the paper
Neomarkers ErbB-3 mouse monoclonal antibody was used to carry out antibody blocking assays in order to investigate the signal cross talk between ErbB2 and PR receptor and the effect on breast cancer growth. more
total:20
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 2009 to the paper
Santa Cruz Biotechnology anti-ERBB4 antibody was used in immunoprecipitation and western blot in order to characterize the role of ERBB4 mutations in melanoma. more
total:1
Human corneal epithelial cell proliferation by epiregulin and its cross-induction by other EGF family members. 2007 to the paper
R & D Systems anti-epiregulin antibody was used in immunohistochemistry to study human corneal epithelial cell proliferation by epiregulin and its cross-induction by other EGF family members
total:252
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Millipore anti-ERK1/2 polyclonal antibody (1:10,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediated anti-apoptotic effects. more
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:2
Transcriptional regulation of tissue-specific genes by the ERK5 mitogen-activated protein kinase. 2005 to the paper
Biosource anti-phosphoERK5 antibody was used in western blot to study tissue-specific transcriptional regulation by ERK5 more
total:2
Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. 2005 to the paper
Upstate Biotechnologies Par-3 antibody was used in western blot and immunocytochemistry to study the role of Par-3 in epithelial cell polarization in mammals. more
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:1
Cell-cell contact globally activates microRNA biogenesis. 2009 to the paper
Upstate anti-Ago antibody was used to perform western blot in order to study the association between the cell-cell contact and microRNA biogenesis.
total:2
A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer. 2006 to the paper
Santa Cruz goat polyclonal antibodies generated against either Fes amino-terminal (Fes N-19) or carboxyl-terminal (Fes C-19) peptides were used in western blot to investigate Fes expression in human 293T cells, as well as HT-29 and HCT 116 cells, and in immunohistochemstry to detect Fes expression in normal adult human colon sections and human colorectal cancer cell line HT-29. more
total:1
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 to the paper
Behring rabbit anti-fibrinogen antibody was used to carry out immunofluorescence assays in order to investigate the association for increased expression of urokinase plasminogen activator and megakaryocyte differentiation in Quebec platelet disorder.
total:20
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. 2009 to the paper
Chemicon rabbit polyclonal anti-FGF2 antibody was used in western blot to study the role for endothelial-derived FGF2 in the progression of pulmonary hypertension in humans and rodents. more
total:2
HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. 2006 to the paper
R&D Systems goat polyclonal anti-human FGF-1 antibody was used in ELISA to study the HSulf-2 which selectively mobilizes heparin-bound growth factors and chemokines. more
total:2
Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. 2008 to the paper
R&D Systems FGF9 antibody was used in immunohistochemistry at 5 ug/ml in order to study the role of androgen receptor null cells in prostate cancer bone metastases treatment more
total:17
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Biosource International anti-FGFR-1 (pYpY653/654) antibodies were used to perform western blot and ELISA analyses in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
total:9
Endothelial function of von Hippel-Lindau tumor suppressor gene: control of fibroblast growth factor receptor signaling. 2008 to the paper
Santa Cruz rabbit polyclonal anti-FGFR2 was used to perform western blot in order to show that VHL tumor supppressor gene has endothelial function through fibroblast growth factor receptor signaling. more
total:7
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Santa Cruz mouse anti-FGFR3 was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:5
Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-FGFR4 antibody was used to carry out western blot analysis in order to investigate whether FGFR4 plays a role in promoting the progression of hepatocellular carcinoma. more
total:4
Biomarkers for ragwort poisoning in horses: identification of protein targets. 2008 to the paper
Affiland rabbit (polyclonal) anti-(equine) fibrinogen antibody was used in western blot in order to investigate whether pyrrole toxins induce specific modifications of equine blood proteins that are detectable by proteomic methods more
total:39
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors. 2010 to the paper
Sigma Aldrich anti-fibronectin antibody was used to perform immunocytochemistry and western blot in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors. more
total:3
Correlation of vascular endothelial growth factor-D expression and VEGFR-3-positive vessel density with lymph node metastasis in gastric carcinoma. 2008 to the paper
R&D Systems goat polyclonal anti-VEGF-D antibody was used in immunohistochemistry to study the clinical value of VEGF-D expression and VEGFR-3 positive vessel density in gastric carcinoma with regard to lymphangiogenesis in paraffin sections from human tumor. more
total:8
Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response. 2011 to the paper
Affinity Bioreagents anti-FKBP12 was used to perform western blot in order to show that unfolded protein response is induced by Ire1-unfolded protein interaction. more
total:20
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 to the paper
Santa Cruz anti-FKHR antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters. more
total:18
CAMKII and calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16.. 2013 to the paper
Cell Signaling rabbit anti-mFOXO3(phospho-S252)/hFOXO3(phospho-S253) antibody was used to perform western blot in order to investigate the regulatory effect of calcineurin and CAMKII on the lifespan of Caenorhabditis elegans. more
total:16
The association of vascular endothelial growth factor receptor-1 with the risk of cancer progression following radical prostatectomy. 2008 to the paper
R&D Systems goat anti-human VEGFR-1 polyclonal antibody (catalog number: AF321) was used to perform immunochemistry assays in order to demonstrate that VEGFR-1 expression is not related to the risk of cancer progression following radical prostatectomy. more
total:2
Follistatin-like protein-1 is a novel proinflammatory molecule. 2006 to the paper
R&D Systems FSTL-1 antibody was used in immunohistochemistry to demonstrate Follistatin-like protein-1 as a novel proinflammatory molecule. more
total:1
Progesterone-dependent deoxyribonucleic acid looping between RUSH/SMARCA3 and Egr-1 mediates repression by c-Rel. 2008 to the paper
Santa Cruz Biotechnology FAST-1/2 antibody was used in ChIP assays in order to demonstrate that self-assembling peptide nanofiber scaffolds accelerate wound healing
total:4
Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits. 2008 to the paper
Chemicon monoclonal mouse anti-O4 antibody (clone:81, Cat:MAB345) was used in immunohistochemistry to study what happens in the cerebellar cortex of peripuberal rabbits by using endogenous and exogenously-administered cell proliferation antigens in association with a cohort of typical markers for neurogenesis. more
total:2
Intravascular danger signals guide neutrophils to sites of sterile inflammation. 2010 to the paper
R&D Systems anti-human-FPR1 antibody was used to carry out flow cytometry analysis in order to investigate the mechanism for how neutrophils are recruited to sites of sterile inflammation from the blood. more
total:1
The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells. 2009 to the paper
LifeSpan Biosciences anti-FPRL1 antibody (1:100) was used in flow cytometry in order to study the role of pro-inflammatory peptide LL-37 in the ovarian tumor progression
total:6
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Santa Cruz rabbit anti-FRS was used at 1:250 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:2
Changes in serum inhibin B during normal male puberty. 2005 to the paper
Autodelfia anti-FSH antibody was used in immunocytochemistry to study the changes in serum inhibin B during normal male puberty. more
total:7
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. 2009 to the paper
Thermo Fisher Scientific anti-furin antibody was used in immunocytochemistry in order to investigate the mechanism of the autonomous cholesterol regulation activated by adenovirus membrane protein RID-alpha. more
total:19
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-FYN antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking. more
total:9
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Upstate Biotechnology polyclonal anti-Gab1 antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
total:6
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Upstate anti-Gab2 polyclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
total:2
Vertebrate-specific sequences in the gephyrin E-domain regulate cytosolic aggregation and postsynaptic clustering. 2007 to the paper
Fritschy and Mohler GABAA receptor 1 antibody was used in immunocytochemistry to study the role of specific E-domain regions distinct from the known dimerization interface for controlling gephyrin aggregation. more
total:3
Altered sensitivities to morphine and cocaine in scaffold protein tamalin knockout mice. 2007 to the paper
Chemicon rabbit anti-GABAB2 (1:300) antibody was used in western blot to study how tamalin serves its physiological function in vivo. more
total:5
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
ProteinTech Group anti-PPP1R15A/GADD34 was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
total:3
Galanin receptor 1 has anti-proliferative effects in oral squamous cell carcinoma. 2005 to the paper
Chemicon International rabbit anti-GAL polyclonal antibody was used in ELISA to study the inhibitory effects of galanin receptor 1 on proliferation in oral squamous cell carcinoma. more
total:7
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Abcam anti-BAFF monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:1
Galanin receptor 1 has anti-proliferative effects in oral squamous cell carcinoma. 2005 to the paper
Alpha Diagnostics rabbit anti-GALR2 polyclonal antibody was used in western blot to study the inhibitory effects of galanin receptor 1 on proliferation in oral squamous cell carcinoma.
total:1
Galanin receptor 1 has anti-proliferative effects in oral squamous cell carcinoma. 2005 to the paper
Alpha Diagnostics rabbit anti-GALR3 polyclonal antibody was used in western blot to study the inhibitory effects of galanin receptor 1 on proliferation in oral squamous cell carcinoma.
total:5
Secretin-receptor and secretin-receptor-variant expression in gastrinomas: correlation with clinical and tumoral features and secretin and calcium provocative test results. 2007 to the paper
Chemicon rabbit anti-gastrin polyclonal antibody (1:1000) was used in immunohistochemistry to study secretin-receptor and secretin-receptor-variant expression in gastrinomas more
total:4
Application of light microscopical and ultrastructural immunohistochemistry in the study of goblet cell carcinoid in the appendix. 2008 to the paper
BioGenex Laboratories rabbit anti-human bombesin antibody was used in immunohistochemistry in order to develop a combined histochemical and immunohistochemical procedure to reveal the dual nature of goblet cell carcinoide more
total:1
Knocking down gene expression for growth hormone-releasing hormone inhibits proliferation of human cancer cell lines. 2008 to the paper
Santa Cruz Biotechnology anti-GHRH antibody was used to perform western blot in order to study inhibition of the GHRH gene expression affects proliferation of human cancer cell lines.
total:1
Synergistic inhibition of growth of lung carcinomas by antagonists of growth hormone-releasing hormone in combination with docetaxel. 2006 to the paper
Dr.Andrew V. Schally (Veterans Affairs Medical Center) pGHRH-R antibody (1:2,000) was used in western blot to study the effect of antagonists of growth hormone-releasing hormone (GHRH) MZ-J-7-138 and JV-1-92 on H460 human non-small cell lung carcinoma (NSCLC) xenografted orthotopically into nude mice.
total:91
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Chemicon anti-GFAP antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:2
Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r). 2007 to the paper
Abcam GLP-1R antibody was used in western blot to study protein expression of GLP-1R to reveal tissue-specific strain differences in pancreas (congenic>B6) and stomach (B6>congenic). more
total:13
Deletion of the mitochondrial flavoprotein apoptosis inducing factor (AIF) induces beta-cell apoptosis and impairs beta-cell mass. 2009 to the paper
Sigma anti-glucagon antibody was used to perform immunohistochemistry in order to study the role of mitochondrial flavoprotein apoptosis inducing factor. more
total:6
G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function. 2005 to the paper
Santa Cruz Biotechnology polyclonal anti-Galpha12 antibody (which recognizes N-terminal peptides of Galpha12 proteins) was used in western blot and immunocytochemistry to study the effects of interaction between G 12 and SNAP on VE-cadherin localization at endothelial junctions and barrier function. more
total:5
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
Abcam rabbit anti-GNAI2 antibody was used to carry out immunoprecipitation assays in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
total:6
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-GNAI3 antibody was used to carry out immunoprecipitation assays in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
total:11
Caveolin-1 alters Ca(2+) signal duration through specific interaction with the G alpha q family of G proteins. 2008 to the paper
Santa Cruz rabbit anti-Galphaq antibody was used in immunocytochemistry to study the effect of the interaction between caveolin-1 and the Galphaq family of G proteins on Ca2+ signal duration. more
total:4
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
United States Biological rabbit anti-GNAS antibody was used to carry out immunoprecipitation assays in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
total:1
Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon. 2006 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-Galphagust antibody (I-20, sc-395) was used in immunohistochemistry to study the association of alpha-subunit of gustducin with PYY and GLP-1 in histological sections of the human colon.
total:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 to the paper
Dr. W. Simonds (NINDK) rabbit anti-VAChT antibody was used in western blot to study the localization and differential interaction of R7 RGS proteins with R7BP and R9AP in neurons of vertebrate retina.
total:5
Presence of immunoreactive gonadotropin releasing hormone (GnRH) and its receptor (GnRHR) in rat ovary during pregnancy. 2008 to the paper
Chemicon International mouse monoclonal anti-GnRH antibody (1:200) was used in immunohistochemistry to study its cellular localization in the rat ovary. more
total:1
Differential expression of syndecans and glypicans in chronically inflamed synovium. 2008 to the paper
Santa Cruz Biotechnologies anti-glypican-3 antibody was used in immunohistochemistry to investigate which HSPGs are expressed in knee joint synovia from patients with different forms of arthritis and normal individuals.
total:4
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. 2009 to the paper
Santa Cruz Biotechnology mouse anti-granzyme B monoclonal antibody was used to carry out immunofluorescence assays in order to investigate the mechanism for IL-33 in promoting allergic inflammation. more
total:3
T cell receptor-induced activation of phospholipase C-gamma1 depends on a sequence-independent function of the P-I region of SLP-76. 2005 to the paper
Upstate Cell Signaling Solutions anti-Gads polyclonal antibody was used in western blot to demonstrate T-cell receptor-induced activation of phospholipase C-gamma1 by a sequence-independent function of the P-I region of SLP-76. more
total:5
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. 2011 to the paper
Cell Signaling Technology anti-Grb10 was used to perform western blot in order to show that how growth factor signaling is inhibited by mTOR through mTOR-regulated phosphoproteome. more
total:36
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal against Ron antibody was used in western blot in order to demostrate the expression of PAX 5 and the regulation for c-Met transcription in small cell lung cancer. more
total:4
The adaptor Grb7 links netrin-1 signaling to regulation of mRNA translation. 2007 to the paper
Santa Cruz Biotechnology anti-Grb7 antibody was used in western blot to identify Grb7 as a new RNA-binding protein that serves as the molecular adaptor for transmitting Netrin-1 signals. more
total:5
Arrestin competition influences the kinetics and variability of the single-photon responses of mammalian rod photoreceptors. 2009 to the paper
Affinity BioReagent monoclonal anti-rhodopsin kinase 1a antibody (1:1,000, MA1-720) was used in western blot to investigate the role of arrestin in mammalian rod's single-photon responses more
total:9
Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2. 2008 to the paper
Santa Cruz Biotechnolog GRK2 polyclonal antibody was used to immunodetect myocardial levels in order to study the uncoupling of myocardial beta-Adrenergic receptor signaling during coronary artery bypass grafting: The Role of GRK2 more
total:3
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-GRK5 antibody was used to perform western blot in order to study the important role of GRK4 in D3 receptor's signaling in human proximal tubule cells. more
total:7
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 to the paper
BD Biosciences mGluR1 antibody was used in western blot to study the role of molecular alterations in the cerebellum of the PMCA2-null in Purkinje neurons. more
total:4
The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival. 2009 to the paper
Upstate anti-mGluR2 was used to perform western blot in order to prove that the mGluR2 activation plays an important role in signal transduction pathways and neuronal cell survival. more
total:3
Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin. 2005 to the paper
Upstate Biotechnology rabbit polyclonal anti-mGluR5 antibody was used in western blot and immunoprecipitation to study metabotropic glutamate receptor signaling more
total:1
Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon. 2005 to the paper
Dr. Robert T. Jensen anti-GRP-R antibody was used in immunohistochemistry to study the role of neuromedin B and its receptor in both normal and malignant epithelial cells lining the colon.
total:23
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Santa Cruz Biotechnology anti-GSK3 alpha antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
total:79
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Santa Cruz Biotechnology anti-GSK3 beta antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
total:1
Prolonged illumination up-regulates arrestin and two guanylate cyclase activating proteins: a novel mechanism for light adaptation. 2009 to the paper
Affinity BioReagents mouse anti-GCAP1 antibody was used in western blot in order to investigate the mechanism for light adaptation-associated changes in gene expression caused by prolonged illumination.
total:3
Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules. 2009 to the paper
Santa Cruz goat anti-GW182 antibody (1:100) was used to perform immunofluorescence in order to prove that the association of AKAP350A and CCAR1 with RNA stress granules is microtubule dependent. more
total:26
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Calbiochem/Merck anti-H-Ras antibody was used to perform western blot in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:1
Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin. 2007 to the paper
Dr. Peter Cheung (Ontario Cancer Institute) rabbit H2A.Z-specific antibodies (the H2A.Z-L1 antibody was raised against the peptide sequence KSSRTTSHGR, and the H2A.Z-C antibody was raised against the peptide sequence IPHIHKSLIGKKGQQKTV) was used in western blot and immunocytochemistry to study H2A.Z monoubiquitylation as the marker for its association with euchromatin or facultative heterochromatin
total:62
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Millipore Gamma-H2AX antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
total:32
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 to the paper
Upstate anti-H3K4 antibody was used to perform RNA immunoprecipitation in order to analyze histone methylation at transcription start sites in human-specific prefrontal neurons of brain. more
total:5
Hsp90alpha recruited by Sp1 is important for transcription of 12(S)-lipoxygenase in A431 cells. 2005 to the paper
Upstate Biotechnology acetyl-H3 antibody was used in ChIP assay to study 12 (S) Lipoxygenase transcription in A431 cells more
total:11
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Active Motif anti-H4K12Ac antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
total:6
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
R&D Systems goat anti-HB-EGF polyclonal antibody was used in immunoprecipitation and immunohistochemistry (1:50) in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:4
Metastatic embryonal carcinoma in the maxillary gingiva. 2008 to the paper
DAKO anti-HCG antibody was used to perform immunohistochemistry in order to study the metastases of embryonal carcinoma in the maxillary gingiva. more
total:4
Repeated amphetamine administration induces Fos in prefrontal cortical neurons that project to the lateral hypothalamus but not the nucleus accumbens or basolateral amygdala. 2008 to the paper
Santa Cruz Biotechnology anti-orexin A antibody (1:1000) was used in immunohistochemistry in order to to identify the mPFC subcortical pathway (s) activated by a sensitizing regimen of AMPH more
total:54
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-HDAC1 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:2
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Abgent anti-HDAC10 antibody was used to perform western blot in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression. more
total:1
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Abgent anti-HDAC10 antibody was used to perform western blot in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression.
total:24
High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo. 2009 to the paper
Abcam anti-HDAC2 antibody was used to perform immunohistochemistry in order to study the association between the high class I HDAC activity and RelA/p65 activation in pancreatic cancer. more
total:21
Histone deacetylase complexes promote trinucleotide repeat expansions. 2012 to the paper
Santa Cruz Biotechnology anti-HDAC3 antibody was used to perform western blot assay in order to identify novel histone deacetylase complexes that promote expansions of trinucleotide repeats. more
total:6
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Active Motif anti-HDAC4 antibody was used to perform ChIP assays in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression. more
total:6
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 to the paper
Assay Biotech anti-phospho-HDAC5 (Ser498) antibody was used for western blot in order to investigate the role of CaMKII in the regulation of pressure overload-induced cardiac hypertrophy to heart failure in mice. more
total:9
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. 2010 to the paper
Santa Cruz rabbit anti-HDAC6 antibody (WB, 1:2000; IF, 1:500) was used to perform western blot and immunofluorescence in order to study knockdown of TDP-43 mediated HDAC6 downregulation. more
total:3
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Novus Biologicals anti-HDAC7 antibody was used to perform ChIP assays in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression. more
total:3
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Santa Cruz Biotechnology anti-HDAC8 antibody was used to perform western blot in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression. more
total:2
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. 2009 to the paper
Santa Cruz Biotechnology anti-HDAC9 antibody was used to perform western blot in order to study the role of histone deacetylase (HDAC) in the regulation of HIV-1 expression. more
total:69
Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. 2008 to the paper
Zymed Laboratories anti-c-erbB-2 antibody was used in immunohistochemistry to investigate the relationship between amphiregulin expression and liver metastases of colorectal cancer. more
total:3
Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer. 2009 to the paper
Chemicon Hes1 antibody was used in western blot in order to generate monoclonal antibodies to evaluate therapeutic potential of targeting EphA2 in pancreatic tumor. more
total:1
Hey1, a mediator of notch signaling, is an androgen receptor corepressor. 2005 to the paper
Chemicon International rabbit anti-human Hey1 affinity-purified polyclonal antibody was used in western blot, immunoprecipitation, and immunohistochemistry to identify Hey1 as an androgen receptor corepressor.
total:63
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
BD Transduction Laboratories anti-HIF-1a antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:1
Testis/sperm-specific histone 2B in the sperm of donors and subfertile patients: variability and relation to chromatin packaging. 2007 to the paper
Chemicon International TSH2B antibody was used in western blot to assesse the association of TSH2B with chromatin compaction status.
total:1
p53 chromatin epigenetic domain organization and p53 transcription. 2009 to the paper
Abcam anti-histone H2Bantibody was used to perform immunoprecipitation in order to demonstrate that physical barrier due to the folding of chromatin in domain II can give rise to the depletion of RNA polymerase II.
total:5
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Abcam anti-Histone 3, anti-H3 K9Me, and anti-H3 S10ph antibodies were used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:6
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Abcam anti-H2A antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
total:10
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-H2B antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:17
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Millipore rabbit anti-pHH3 was used at 1:500 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:1
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes. 2008 to the paper
Upstate anti-Ac-H4 antibody was used to perform immunoprecipitation in order to study the association between ING4 and the activity of NF-kappa B molecules bound with target gene promoters.
total:68
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-HSP90 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:1
Enhanced expressions of microvascular smooth muscle receptors after focal cerebral ischemia occur via the MAPK MEK/ERK pathway. 2008 to the paper
Santa Cruz goat antihuman 5-HT1B antibody was used in immunohistochemistry diluted at 1:100 in order to study the role of the MEK/ERK pathway in receptor expression following ischemic brain injury using the specific MEK1 inhibitor U0126
total:1
Serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients. 2006 to the paper
Santa Cruz Biotechnology goat anti-human serotonin 6 receptor antibody (Santa Cruz sc-26668) was used in tissue sections from human brain and in immunohistochemistry to study the expression of serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients.
total:12
A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta. 2013 to the paper
Millipore anti-active-beta-catenin antibody was used to perform immunohistochemistry to study the role of Gcm1 and Fzd5 in regulating trophoblast differentiation and sites of chorionic branching morphogenesis. more
total:13
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Abcam rabbit anti-IGF-1 antibody was used in western blot to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:40
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Santa Cruz Biotechnology PE-conjugated anti-IGF-1R antibody was used in flow cytometry to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:117
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
Santa Cruz anti-I-kappa B alpha antibody was used to perform western blot in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-IKKalpha monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:36
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Millipore anti-IKK2 antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
total:46
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
R&D systems anti-IL8 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:9
Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis. 2008 to the paper
Serotec anti-human INHBA was used to perform immunohistochemistry in dilution 1:300 in order to show that differentially overexpressed genes in gastric cancer are revealed by combining large-scale gene expression profiling and network analysis. more
total:3
A crucial role of MafA as a novel therapeutic target for diabetes. 2005 to the paper
Dako guinea pig polyclonal anti-insulin antibody was used in immunohistochemistry to study the role of MafA for therapy of diabetes. more
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
total:22
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti subunit of insulin receptors (IR) antibody was used in western blot and immunocytochemistry to test the hypothesis that insulin signaling provides a physiological defense mechanism against the synaptotoxicity of Abeta-derived diffusible ligands. more
total:28
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal integrin beta3 antibody (1:1000) was used in western blot in order to study the role of activated state of p42/44 and p38 in MMP-13 expression. more
total:10
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 to the paper
Santa Cruz mouse anti-IRAK-1 was used to perform western blot in order to show that IRAK-1 blockade is important for tolerance of human DCs induced by TLR2 and TLR4 stimulation. more
total:37
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. 2011 to the paper
Invitrogen anti-phospho-IRS (Y612) was used to perform western blot in order to show that Grb10 was indentified as a negative regulator of insulin signaling by phosphoproteomic analysis. more
total:13
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Upstate Irs2 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models more
total:3
Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation. 2009 to the paper
BD Biosciences Itch monoclonal antibody was used to perform western blot and immunoprecipitation in order to demonstrate the key mechanisms that regulate p63 protein stability in vivo. more
total:5
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 to the paper
Calbiochem IP3R1 antibody was used in western blot and immunohistochemistry to study the role of molecular alterations in the cerebellum of the PMCA2-null in Purkinje neurons. more
total:2
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. 2005 to the paper
Santa Cruz Biotechnology goat anti-IP3R2 antibody was used in western blot to study the binding of phospholipid scramblase 1 to the promoter region of the inositol 1, 4, 5-triphosphate receptor type 1 more
total:2
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
Santa Cruz Biotechnologies Biosystems anti-JAGGED2 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:12
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
R&D Systems anti-Jagged1 antibody was used to perform flow cytometry in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
total:34
Covering a broad dynamic range: information processing at the erythropoietin receptor. 2010 to the paper
Upstate anti-JAK2 antibody was used to carry out immunoprecipitation assay and western blot analysis in order to determine the receptor property of erythropoietin receptor during receptor signaling activation. more
total:193
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-JNK1 monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:9
MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA. 2010 to the paper
Santa Cruz Biotechnology anti-JunB antibody was used for western blot in order to investigate the roles of MDA5 and PTPN2 in the regulation of pancreatic cell responses to the viral by-product double-stranded RNA. more
total:2
A phosphorylation-acetylation switch regulates STAT1 signaling. 2009 to the paper
Santa Cruz Biotechnology GCN5 antibody was used for western blot in order to investigate the role of phosphorylation-acetylation switch in the regulation of STAT1 signaling. more
total:3
Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer. 2008 to the paper
Abcam anti-KiSS1 antibody was used in western blot to study the effect of the large isoform of MRJ (DNAJB6) on malignant activity of breast cancer. more
total:5
Vascular precursors in developing human retina. 2008 to the paper
Assay Designs anti-SCF antibody was used to perform immunohistochemistry in order to study vascular precursors of human retina. more
total:1
Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated. 2010 to the paper
DAKO anii-CKH antibody was used to carry out immunohistochemistry assays in order to investigate the regulation of Estrogen receptor beta activated apoptosis and the role of its agonist in cancer treatment.
total:1
Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer. 2008 to the paper
ABGENT rabbit anti-human Dkk-4 antibody was used to perform immunohistochemistry in order to investigate the expression alteration of dickkopfs (Dkks) and kremen2 (Krm2) in gastrointestinal cancer.
total:2
Hippo pathway effector Yap is an ovarian cancer oncogene. 2010 to the paper
Bethyl Laboratories anti-Lats-1 antibody was used in western blot to study the effect of the hippo pathway effector Yap on the progression of ovarian cancer. more
total:2
A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization. 2006 to the paper
Santa Cruz Biotechnology anti-KPM/Lats2 antibody was used in immunocytochemistry to study the effect of Lats2 on p53 ubiquitination and activation in human U2OS cells. more
total:18
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Upstate Biotechnology Lck antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts. more
total:10
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 to the paper
Santa Cruz anti-LDLr antibody was used in western blot in order to show that Wnt/catenin signaling, osteoblast function, and bone formation can be negatively regulated by the N-cadherin-axin-LRP5 interaction. more
total:5
Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression. 2009 to the paper
Cell Signaling Technology rabbit polyclonal anti-LEF1 antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the role for AEG1 in regulating Hepatocellular carcinoma pathogenesis. more
total:6
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-Ob antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:1
Cytochrome b5 expression in gonadectomy-induced adrenocortical neoplasms of the domestic ferret (Mustela putorius furo). 2008 to the paper
ATCC mouse anti-human LHR antibody was used in immunohistochemistry at 1:100 dilution in order to demonstrate that that cyt b5 is upregulated during gonadectomy-induced adrenocortical neoplasia and is a marker of androgen synthetic potential in these tumors
total:7
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. 2008 to the paper
Santa Cruz Biotechnology anti-Lkb1 antibody was used to perform western blot and immunohistochemistry in order to study the acinar polarity defects and cystic neoplasms induced by Lkb1-deficient in pancreas. more
total:1
The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases. 2006 to the paper
Abgent anti-LPA1 antibody was used to perform western blot in order to study the role of type 1 lysophosphatidic acid(LPA1) receptor in deal with bone metastases.
total:2
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 to the paper
Cell Signaling anti-LRP5 antibody was used in western blot in order to show that Wnt/catenin signaling, osteoblast function, and bone formation can be negatively regulated by the N-cadherin-axin-LRP5 interaction. more
total:6
Blocking the Wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family. 2010 to the paper
Santa Cruz anti-LRP6 antibody was used to perform western blot in order to study a mechanism for an angiogenic inhibitor in the serine proteinase family inhibitor by blocking Wnt pathway more
total:2
Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. 2005 to the paper
LifeSpan Biosciences rabbit anti-human BLT1 receptor antibody was used in western blot and immunohistochemistry to study leukotriene B4 signaling in vascular smooth muscle cells in atherosclerosis and intimal hyperplasia more
total:1
Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. 2005 to the paper
LifeSpan Biosciences rabbit anti-human BLT2 receptor antibody was used in immunohistochemistry to study leukotriene B4 signaling in vascular smooth muscle cells in atherosclerosis and intimal hyperplasia
total:20
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 to the paper
Santa Cruz anti-Lyn 44 antibody was used to perform western blot in order to study the roles of the lipid raft-dependent Fc secre tRI ubiquitination in the regulation of receptor endocytosis. more
total:1
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 to the paper
Santa Cruz goat anti-NRAGE antibody was used to perform western blotting in order to determine the role of NRAGE in regulating NF-kappaB activity.
total:10
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
Cell Signaling Technologies phospho-specific and total anti-p38antibody was used to perform western blot in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
total:2
Activation of p38 has opposing effects on the proliferation and migration of endothelial cells. 2005 to the paper
Cell Signaling Technology polyclonal anti-p38 delta antibody was used in human umbilical vein endothelial cells (HUVECs) and in western blot to study the effect of enhanced p38 MAPK activity on endothelial cell function. more
total:1
Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk. 2005 to the paper
Santa Cruz Biotechnology MC1R antibody (N-19) antibody was used in western blot and immunohistochemistry to study its expression in skin cancer abd red hair persons
total:1
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1. 2008 to the paper
Santa Cruz rabbit anti-Dbl antibody was used to perform immunoprecipitation and western blot in order to show that Nm23-H1 negatively regulate cell migration and tumor metastasis by modulating the activity of Dbl1.
total:1
Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 by binding to the proximal segment of the receptor C-terminal tail. 2005 to the paper
Chemikon affinity-purified chicken anti-MCH-1 receptor antibody was used in immunocytochemistry to study the effect of periplakin on G protein activation by the melanin-concentrating hormone receptor-1
total:14
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
Santa Cruz anti-MCP-1 antibody was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
total:38
TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. 2010 to the paper
Calbiochem anti-Hdm2 antibody was used for western blot in order to investigate the role of TGFB1 in the regulation of Mdm2 expression and late-stage breast cancer metastasis. more
total:6
A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation. 2006 to the paper
Santa Cruz monoclonal anti-MEF2 antibody was used in immunoprecipitation to study a mechanism underlying postsynaptic differentiation that may modulate activity-dependent synapse development and plasticity in the brain.. more
total:3
c-MYC independent nuclear reprogramming favors cardiogenic potential of induced pluripotent stem cells. 2010 to the paper
Proteintech rabbit anti-Mef2c antibody (10056-1-AP; dilution 1:50) was used to perform immunocytochemistry in order to determine the relationship between the cardiogenic potential of iPS and the nuclear reprogramming. more
total:57
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Cell Signaling Technology anti-MEK1 antibody was used to perform flow cytometry and immunochemistry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:16
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. 2010 to the paper
Cell Signaling Technologies anti-phospho-MEK1/2 antibody was used to perform western blot in order to study the discrimination between the yeast and hyphal forms of C. albicans in epithelial cells via a biphasic MAPK response. more
total:2
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 to the paper
Bethyl Laboratories anti-menin antibody was used for coimmunoprecipitation in order to illustrate the role of c-Myb in MLL-associated leukemogenesis. more
total:18
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Cell Signaling Technology anti-MAPKAPK 2 (pT334) was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:1
Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells. 2005 to the paper
Cell Signaling anti-phospho-MNK1 (Thr197/202) antibody was used in human NK92 cells and in western blot to study the role for the interleukins 2 and 15 in regulating Ets1 expression in human natural killer cells.
total:8
Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1. 2010 to the paper
Santa Cruze Biotechnology anti-human MMP-3 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes. more
total:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 to the paper
Epitomics anti-MMP-9 antibody was used in immunohistochemistry to study the mechanism of protein kinase D1 for inhibiting breast tumour cell invasion. more
total:1
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Abgent anti-Mob1A antibody was used in western blot in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis.
total:2
Perturbation of the P-body component Mov10 inhibits HIV-1 infectivity. 2010 to the paper
Proteintech Group anti-Mov10 antibody was used to perform western blotting in order to study if overexpression of Mov10 in cells would inhibit HIV-1 infectivity. more
total:1
The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 2009 to the paper
Abgent anti-MTMR4 antibody was used to perform western blot in order to study the role of Nedd4 plays in the biological process of muscle breakdown.
total:2
Modulation by melatonin of glutamatergic synaptic transmission in the carp retina. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal MT1 receptor antibody was used in western blot and immunohistochemistry to study modulation of glutamatergic synaptic transmission in the carp retina by melatonin. more
total:1
Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. 2006 to the paper
Santa Cruz Biotechnology goat affinity-purified polyclonal anti-MT2 antibody (sc-28453) were used in human placental tissue and placental choriocarcinoma cell lines, and which were used in western blot and immunocytochemistry, to study the expression and role of melatonin receptors in human placenta choriocarcinoma cell lines.
total:33
A gene signature-based approach identifies mTOR as a regulator of p73. 2008 to the paper
Santa Cruz polyclonal anti-mTOR (N-19 (alpha-FRAP) was used to perform western blot in order to show that mTOR is identified as a regulator of p73 by a gene signature-based approach. more
total:2
Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G. 2005 to the paper
Incstar rabbit anti-OPRM1 antibody was used in western blot to detect OPRM1 in CHO cells transfected with wild type and variant OPRM1. more
total:3
Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. 2008 to the paper
eBioscience rabbit MyD88 antibody was used to perform western blot in order to study TLR2 and TLR4 expression in monocytes from T1DM patients. more
total:3
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
Chemicon anti-mouse MAG antibody (1:5000) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation. more
total:1
BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity. 2005 to the paper
Genemed anti-myosin IXb antibody made against the C-terminal peptide CSASTESLLEERAVRGAAEE was used in western blot to study the role of BIG1 as a binding partner of myosin IXb to regulate its Rho-GTPase activating protein activity.
total:14
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-p300 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:3
The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 2009 to the paper
Upstate anti-Nedd4 antibody was used to perform western blot in order to study the role of Nedd4 plays in the biological process of muscle breakdown. more
total:7
CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha. 2007 to the paper
Axxora Nedd8 antibody was used in western blot to demonstrate that CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha. more
total:1
The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. 2009 to the paper
Santa Cruz Biotechnology anti-Net1 antibody was used to carry out western blot analysis in order to investigate the regulation of constitutive Vav3 expression along with cell plasticity and migration by dioxin receptor.
total:7
Role of placenta growth factor in malignancy and evidence that an antagonistic PlGF/Flt-1 peptide inhibits the growth and metastasis of human breast cancer xenografts. 2007 to the paper
Santa Cruz Biotechnology NRP-1 antibody was used in western blot and immunohistochemistry to study the role of placenta growth factor in malignancy. more
total:1
The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression. 2009 to the paper
Biomol NTS rabbit antibody was used in immunohistochemistry in order to investigate the role of neurotensin receptor-1 pathway in the regulation of human ductal breast cancer progression.
total:4
Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. 2007 to the paper
BD Biosciences NFATc1 antibody was used in immunohistochemistry to study the role of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. more
total:2
NGF and BDNF signaling control amyloidogenic route and Abeta production in hippocampal neurons. 2008 to the paper
Novus monoclone anti-NGF antibody (30 ug/ml) was used in cell culture in order to study the role of NGF or BDNF signaling in neuronal apoptotic death more
total:10
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 to the paper
Calbiochem rabbit anti-nicastrin antibody was used to perform western blot in order to study the effect of TNF-alpha on gamma-secretase. more
total:1
Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 to the paper
BD Transduction Laboratories anti-NMT1 antibody was used in western blot to detect NMT1 in SK-OV-3 cells treated with NMT1-1 siRNA or NMT2-4 siRNA.
total:1
Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 to the paper
BD Transduction Laboratories anti-NMT2 antibody was used in western blot to detect NMT2 in SK-OV-3 cells treated with NMT1-1 siRNA or NMT2-4 siRNA.
total:3
Bone morphogenetic protein 9 induces the transcriptome of basal forebrain cholinergic neurons. 2005 to the paper
Regeneron Pharmaceuticals noggin antibody was used in western blot (50 ng/ml) to study gene expression patterns in septal cultures of embryonic day 14 mice and rats grown in the presence or absence of BMP9. more
total:17
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. 2010 to the paper
Epitomics anti-Notch1 antibody was used to carry out western blot analysis in order to investigate the regulation of Notch signaling and cell differentiation by mTOR signaling. more
total:1
Neuropeptide Y modulates effects of bradykinin and prostaglandin E2 on trigeminal nociceptors via activation of the Y1 and Y2 receptors. 2007 to the paper
Immunostar Y1 receptor antibody was used in immunohistochemistry to evaluate the effect of Y1 and Y2 receptor activation on nociceptors stimulated by bradykinin (BK) and prostaglandin E2 (PGE2).
total:4
Selectively oncolytic mutant of HSV-1 lyses HeLa cells mediated by Ras/RTN3. 2007 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-Ras antibody was used in western blot to study mechanism mtHSV was targeted for treating tumors but not other organs. more
total:3
Immortalization and characterization of lineage-restricted neuronal progenitor cells derived from the porcine olfactory bulb. 2008 to the paper
Abcam rabbit anti-neuregulin-1 antibody (1:100) was used in immunocytochemistry in order to study the role of CCR5 in the migration of pulmonary fibrocytes and the promotion of metastasis more
total:3
The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression. 2009 to the paper
Santa Cruz NTSR1 goat polyclonal antibody was used for immunohistochemistry in order to investigate the role of neurotensin receptor-1 pathway in the regulation of human ductal breast cancer progression. more
total:10
Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. 2008 to the paper
R&D Systems monoclonal anti-Nur77 was used to perform immunocytochemistry in dilution 1:200 in order to show that acetylshikonin and analogues induce apoptosis through orphan nuclear receptor Nur77-mediated apoptotic pathway in cancer cells. more
total:2
Human cone photoreceptor dependence on RPE65 isomerase. 2007 to the paper
Santa Cruz Biotechnology polyclonal anti-human red/green opsin (sc-22117, 1:100) was used in immunohistochemistry to study human cone photoreceptor dependence on RPE65 isomerase more
total:2
Human cone photoreceptor dependence on RPE65 isomerase. 2007 to the paper
Santa Cruz Biotechnology goat polyclonal anti-human blue opsin (sc-14363, 1:50) was used in immunohistochemistry to study human cone photoreceptor dependence on RPE65 isomerase more
total:1
The adaptor Grb7 links netrin-1 signaling to regulation of mRNA translation. 2007 to the paper
Santa Cruz Biotechnology anti-KOR antibody was used in western blot to identify Grb7 as a new RNA-binding protein that serves as the molecular adaptor for transmitting Netrin-1 signals.
total:1
Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. 2008 to the paper
Neuromics anti-N/OFQ antibody (1:5,000) was used in immunohistochemistry in order to demonstrate that the Hcrt and N/OFQ systems interact to coordinately modulate SIA
total:1
Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells. 2008 to the paper
Millipore anti-2H8 antibody was used to perform immunohistochemistry in order to study the roles of Ras signaling during the direction of endothelial specification of VEGFR2+ vascular progenitor cells.
total:8
Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. 2008 to the paper
Santa Cruz Biotechnology anti-orexin-B antibody (1:5,000) was used in immunohistochemistry in order to demonstrate that the Hcrt and N/OFQ systems interact to coordinately modulate SIA more
total:12
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Calbiochem anti-osteopontin antibody (1:100) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:4
Prolactin activates mitogen-activated protein kinase signaling and corticotropin releasing hormone transcription in rat hypothalamic neurons. 2009 to the paper
Chemicon Temecula OT (oxytocin) monoclonal antibody was used in immunohistochemistry in order to investigate the mechanism for the prolactin-mediated hypothalamic pituitary adrenal axis inhibition during lactation in hypothalamic neurons. more
total:2
Constitutive and ligand-induced nuclear localization of oxytocin receptor. 2007 to the paper
Research Diagnostic polyclonal anti-OTR antibody directed towards the N-terminal was used in western blot to demostrate the constitutive and ligand-induced nuclear expression of oxytocin receptor. more
total:8
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p107 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-p110alpha was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:9
Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling. 2010 to the paper
Santa Cruz Biotechnology Inc anti-p130CAS antibody was used for immunoblotting in order to illustrate the mechanism of silencing SCARA5 in HCC tumorigenesis and metastasis. more
total:178
Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. 2012 to the paper
Abcam mouse anti-p21 antibody was used to perform western blot in order to study the mechanism through which doxorubicin suppressed tumor growth. more
total:118
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. 2012 to the paper
BD Pharmingen anti-p27CDKN1B antibody was used to perform western blot in order to show that p53-dependent cell proliferation and survival could be regulated by atg7. more
total:1
Regulation by P2X7: epithelial migration and stromal organization in the cornea. 2008 to the paper
Chemicon P2Y4 antibody was used in immunohistochemistry in order to study the role of the P2X7 receptor in the repair of in vivo corneal epithelial debridement wounds
total:2
Possible role of extracellular nucleotides in ectopic ossification of human spinal ligaments. 2008 to the paper
Alomone Labs anti-P2Y1 antibody was used in western blot to study the role for extracellular nucleotides in ectopic ossification of human spinal ligaments in human cells. more
total:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
total:189
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 to the paper
Biosource International anti-p38 antibody was used to perform western blot in order to study the effect of NFAT5 on hyperosmolar stressed human limbal epithelial cells. more
total:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-p50 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:250
JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. 2014 to the paper
Abcam anti-p53 antibody was used to perform western blotting in order to study JMJD6 promotes colon carcinogenesis through negative regulation of p53. more
total:146
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Santa Cruz anti-p65 antibody was used to perform immunofluorescence in order to study the role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
total:60
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
Cell Signaling anti-S6K1 and phospho-T389 S6K1 was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation. more
total:17
Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett's epithelial cell line. 2008 to the paper
Novus Biologicals anti-p75NTR antibody was used to perform immunocytochemistry in order to show that cellular phenotype can be changed after exposure to acid and bile salt in Barrett's epithelial cell line. more
total:43
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Upstate anti-p85 pAb was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:20
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Santa Cruz anti-RSK-1 antibody (1:1,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediates anti-apoptotic effects. more
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal regulator PA200 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
total:4
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Santa Cruz Biotechnology anti-CBP antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:16
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. 2010 to the paper
Novus Biologicals goat anti-human plasminogen antibody was used to perform ELISA in order to investigate the interaction between leptospiral endostatin-like protein A and human plasminogen. more
total:7
Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. 2007 to the paper
Santa Cruz Biotechnology PAR1 antibody was used in immunohistochemistry to determine the expression and functions of PARs in the gallbladder epithelium. more
total:6
Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. 2007 to the paper
Santa Cruz Biotechnology PAR2 antibody was used in immunohistochemistry to determine the expression and functions of PARs in the gallbladder epithelium. more
total:175
SIRT6 promotes DNA repair under stress by activating PARP1. 2011 to the paper
Abcam anti-PARP1 was used to perform western blot in order to show that DNA repair could be promoted by SIRT6 through PARP1 activation under oxidative stress. more
total:51
Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma. 2008 to the paper
Upstate mouse monoclonal anti-paxillin was used to perform immunocytochemistry in order to show that Rho/ROCK/MLC pathway could be inhibited by DCL1 in hepatocellular carcinoma. more
total:15
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-PCAF antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:1
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. 2006 to the paper
Abcam PDE10A mouse monoclonal antibody was used in western blot andimmunohistochemistry to study Cellular and subcellular localization of PDE10A.
total:1
Expression of PDE11A in normal and malignant human tissues. 2005 to the paper
FabGennix anti-Cyclic nucleotide phosphodiesterase 11A antibody was used in immunohistochemistry and western blot to study the expression of PDE11A in normal and malignant human tissues.
total:2
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. 2006 to the paper
Chemicon PDE1B1 antibody was used in western blot to study Cellular and subcellular localization of PDE10A. more
total:1
Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells. 2005 to the paper
Santa Cruz Biotech anti-PDE3B antibody was used in western blot to study the suppression of cyclic GMP-specific phosphodiesterase 5 promoting apoptosis and inhibiting growth in HT29 cells.
total:3
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Abcam anti-PDE4 antibody was used in western blot in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
total:1
Short-term or long-term treatments with a phosphodiesterase-4 (PDE4) inhibitor result in opposing agonist-induced Ca(2+) responses in endothelial cells. 2008 to the paper
FabGennix anti-PDE4C antibody was used in western blot to study the effects of longer term pre-treatment with a specific inhibitor of phosphodiesterase-4 (PDE4), on [Ca2+]i, cAMP levels, and PDE activity and expression in HUVEC.
total:1
Expression of the cAMP-phosphodiesterase PDE4D isoforms and age-related changes in follicle-stimulating hormone-stimulated PDE4 activities in immature rat sertoli cells. 2007 to the paper
Santa Cruz Biotechnology anti-PDE4D antibody was used in western blot to evaluate the cAMP response to FSH and the FSH-stimulated PDE activities in proliferating.
total:3
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
Abcam anti-PDE6A antibody(1:200 dilution)was used to perform immunohistochemistry in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
total:2
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
FabGennix anti-PDE6B antibody was used to perform western blot in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
total:2
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
Santa Cruz Biotechnology anti-PDE6G antibody was used to perform western blot in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
total:5
Antiangiogenic characteristics of astrocytes from optic nerve heads with primary open-angle glaucoma. 2008 to the paper
Santa Cruz Biotechnology anti-PDGF-A polyclonal antibody was used to perform western blot in order to study the role of astrocytes on angiogenesis. more
total:5
Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-PDGF-B antibody was used in immunohistochemistry to study whether the expression of tyrosine kinase growth factor receptors is constant or varies between and within individual colon cancer neoplasms. more
total:2
Blocking platelet-derived growth factor-D/platelet-derived growth factor receptor beta signaling inhibits human renal cell carcinoma progression in an orthotopic mouse model. 2005 to the paper
R&D Systems anti-PDGF-D antibody was used in immunocytochemistry to indicate potential therapeutic use of PDGF-D or PDGFR inhibitors to block human renal cell carcinoma tumor progression. more
total:14
PDGFRalpha/beta expression correlates with the metastatic behavior of human colorectal cancer: a possible rationale for a molecular targeting strategy. 2008 to the paper
Santa Cruz Biotechnology anti-PDGFRA antibody was used to perform Western Blot and immunohistochemistry in order to prove that the metastatic behavior of human colorectal cancer correlates with PDGFRalpha/beta expression. more
total:27
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy. 2009 to the paper
Abgent anti-p-PDGFR Tyr579 antibody was used in immunohistochemistry in order to investigate the mechanism of how Akt mediates sterol regulatory element-binding protein 1 (SREBP-1) cleavage induced by EGFR. more
total:1
Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. 2010 to the paper
Millipore mouse anti-Enkephalin antibody was used to carry out immunohistochemistry assays in order to investigate the effect of lossing BDNF receptor in different neurons on control of cocaine reward.
total:1
Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon. 2006 to the paper
Alpco Diagnostics rabbit polyclonal anti-PYY antibody (13-B52-1) was used in immunohistochemistry to study the association of alpha-subunit of gustducin with PYY and GLP-1 in histological sections of the human colon.
total:5
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. 2006 to the paper
Chemicon monoclonal anti-perlecan antibody (MAB 1948) was used in frozen sections from mouse and in immunohistochemistry to study the identification of WARP as a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. more
total:3
Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase. 2009 to the paper
Santa Cruz Biotechnology Mouse anti-platelet factor-4 polyclonal antibody was used to carry out western blot analysis in order to investigate the functionality of platelet TLR2 in the immune and inflammatory response. more
total:4
Self-assembly of filopodia-like structures on supported lipid bilayers. 2010 to the paper
Axxora anti-profilin antibody was used to carry out immunofluorescence assays in order to investigate the mechanism for how filopodia-like structures is self-assembled. more
total:3
A reproducible and quantifiable model of choroidal neovascularization induced by VEGF A165 after subretinal adenoviral gene transfer in the rabbit. 2008 to the paper
Upstate mouse monoclonal anti-FGF/anti-FGF-2 antibody (clone bFM-2) was used in immunohistochemistry to determine the effects of the vascular endothelial growth factor (VEGF) A165 delivered using a high capacity adenoviral vector (HC Ad.VEGF-A) on vascular growth and pathological changes in the rabbit eye. more
total:2
A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients. 2005 to the paper
Dr Stefan Feske anti-PLCgamma antibody was used in western blot to study the defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients. more
total:3
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. 2009 to the paper
Abgent anti-PI3KC3 antibody was used in western blot in order to study the role of Beclin 1 in the regulation of autophagy. more
total:6
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz polyclonal anti-p110beta antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:5
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz anti-p110delta monoclonal antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:11
Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation. 2006 to the paper
Santa Cruz Biotechology anti-p110 gamma antibody was used in western blot in order to investigate the mechanism of the PI3K-IA (phosphatidylinositol 3-kinase Class IA) lipid kinase activity was affected by high NaCl and ionizing radiation. more
total:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Millipore polyclonal anti-human p85 antibody was used to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:1
Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. 2008 to the paper
Abgent rabbit anti-hVps15 antibody was used in western blot to identify the pathway and mechanism by which AAs signal to hVps34 to stimulate mTOR complex1 signaling.
total:1
Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl. 2009 to the paper
Abgent anti-PIP5KI antibody was used to perform western blot in order to study the role of wnt3a and dvl in phosphatidylinositol kinase regulation.
total:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-PKCAalpha antibody was used in western blot in order to study the function of TMX3 in eye development. more
total:27
Protein kinase C in porcine retinal arteries and neuroretina following retinal ischemia-reperfusion. 2009 to the paper
Santa Cruz Biotechnology mouse monoclonal anti-beta-actin antibody (1:5000) was used for western blot in order to investigate the role of PKC in the regulation of porcine retinal ischemia-reperfusion. more
total:35
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. 2009 to the paper
Santa Cruz Biotechnology anti-PKCdelta antibody was used in western blot to study the mechanism underlying PKCalpha suppressing tumor in the intestine. more
total:20
GABAA receptor trafficking is regulated by protein kinase C(epsilon) and the N-ethylmaleimide-sensitive factor. 2010 to the paper
Santa Cruz Biotechnology goat anti-PKC epsilon antibody was used to perform western blot and immunocytochemistry in order to show that NSF and PKC epsilon could regulate GABAA receptor trafficking to affect synaptic inhibition. more
total:25
Alleviating neuropathic pain hypersensitivity by inhibiting PKMzeta in the anterior cingulate cortex. 2010 to the paper
Invitrogen anti-PKC-zeta (1:500) antibody was used in western blot in order to investigate the role of PKM-zeta on neuropathic pain hypersensitivity in cortex. more
total:8
Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport.. 2009 to the paper
Santa Cruz Biotechnology anit-cPLA2a antibody was used to perform western blot and immunocytochemistry to study the role of cPLA2a in the formation of intercisternal tubular continuities and transport through the Golgi complex. more
total:4
Borrelia burgdorferi infection-associated surface proteins ErpP, ErpA, and ErpC bind human plasminogen. 2009 to the paper
Novus Biologicals goat anti-human plasminogen antibody was used to perform ELISA in order to study human plasminogen binding surface proteins ErpP, ErpA, and ErpC in Borrelia burgdorferi infection. more
total:2
Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling. 2008 to the paper
Santa Cruz tPA antibody was used in western blot in order to demonstrate that lithium suppresses Smad3/4-dependent TGF-beta-responsive gene transactivation more
- platelet activating factor receptor antibody
- platelet activating factor receptor gene knockdown
- platelet activating factor receptor cDNA
- platelet activating factor receptor protein
- platelet activating factor receptor inhibitor/activator/substrate/reporter
- platelet activating factor receptor ELISA/assay
- platelet activating factor receptor other
total:1
Relative levels of semen platelet activating factor-receptor (PAFr) and ubiquitin in yearling bulls with high content of semen white blood cells: implications for breeding soundness evaluation. 2007 to the paper
Cayman Chemicals PAF receptor antibody was used in western blot and immunohistochemistry to study the role of PAF receptor in fertility.
total:32
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-PLCG1 antibody was used to carry out western blot analysis and immunoprecipitation assays in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:3
Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. 2005 to the paper
Santa Cruz Biotechnology PLC beta2 antibody was used in western blot to study localization of TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells more
total:19
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. 2008 to the paper
Santa Cruz anti-PP1alpha was used to perform western blot in order to show that SRC-3/AIB1 coactivator function and turnover is regulated by essential phosphatases and a phospho-degron of SRC-3/AIB1 is primary determinants of its turnover. more
total:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate monoclonal anti-PP2Ac antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:2
Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. 2010 to the paper
Santa Cruz goat polyclonal anti-PBP was used to perform western blot in order to show that function of factor H is defective in patients with systemic sclerosis and sclerodermatous GVHD. more
total:2
Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma. 2007 to the paper
Santa Cruz Biotechnology goat polyclonal PP1 gamma C antibody was used in western blot to study the regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma more
total:3
Brain-specific regulator of G-protein signaling 9-2 selectively interacts with alpha-actinin-2 to regulate calcium-dependent inactivation of NMDA receptors. 2006 to the paper
Santa Cruz Biotechnology anti-dopamine- and cAMP-regulated phosphoprotein of 32 kDa (DARPP-32) antibody was used in immunoprecipitation to identify the interaction between RGS9-2 and alpha-actinin-2. more
total:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate polyclonal anti-PP2A-A antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:2
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. 2007 to the paper
Sigma-Aldrich polyclonal antibody to the PP2APR65 subunit was used to perform western blot in order to investigate the functions of salt-inducible kinase-1. more
total:4
Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis. 2009 to the paper
Sigma-Aldrich anti-calcineurin A antibody was used in western blot in order to deduce that calcineurin activity and apoptosis of leukemic lymphocytes can be modulated by GC-mediated upregulation of RCAN1-1. more
total:2
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. 2005 to the paper
Chemicon rabbit anti-calcineurin antibody was used in immunohistochemistry to study the mechanisms that trigger astrocyte activation. more
total:3
Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. 2006 to the paper
Sigma CnB1 antibody was used in western blot to demonstrate direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. more
total:15
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Cell Signaling Technologies anti-PRKAA1 antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:4
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
R&D technologies anti-PRKAA2 antibody was used to carry out western blot analysis and ChIP assays in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 to the paper
Santa Cruz Biotechnology anti-the catalytic D subunit of PKA antibody C-20 was used in human fibrosarcoma HT1080 cells and in western blot to study the role for tyrosine phosphorylation in full-scale activation of the eIF2alpha RNA-dependent protein kinase. more
total:1
The ancient drug salicylate directly activates AMP-activated protein kinase. 2012 to the paper
Abcam anti-AMPK-gamma1 was used to perform western blot in order to show that AMPK could be activated by salicylate directly.
total:9
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIalpha was used in immunohistochemistry to detect the PKA subunit RIalpha in human adrenal samples more
total:9
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Santa Cruz Biotechnology anti-PKA RII antibody was used in immunoprecipitation in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
total:3
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIIbeta was used in immunohistochemistry to detect the PKA subunit RIIbeta in human adrenal samples more
total:12
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. 2007 to the paper
Cell Signaling Technology phospho-Pan-PKC antibody (1:1,000) was used in western blot to study melanoma cell motility by the Wnt5A/protein kinase C pathway through the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition more
total:5
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKC-eta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
total:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKCtheta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
total:7
Hsp90/Hsp70 chaperone machine regulation of the Saccharomyces MAL-activator as determined in vivo using noninducible and constitutive mutant alleles. 2008 to the paper
Molecular Probes anti-PGK antibody was used in western blot in order to study the roles of Hsp90, Hsp70, and Sti1 in the regulation of the Saccharomyces MAL-activator more
total:3
PROPELLER MRI visualizes detailed pathology of hippocampal sclerosis. 2008 to the paper
Serotec polyclonal anti-dynorphin antibody was used in immunohistochemistry to explore PROPELLER image quality of the hippocampus compared to routine sequences in sections from human hippocampal specimen. more
total:38
The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression. 2009 to the paper
Santa Cruz PR monoclonal antibody was used in immunohistochemistry in order to investigate the role of neurotensin receptor-1 pathway in the regulation of human ductal breast cancer progression. more
total:1
The endocrine-gland-derived vascular endothelial growth factor (EG-VEGF)/prokineticin 1 and 2 and receptor expression in human prostate: Up-regulation of EG-VEGF/prokineticin 1 with malignancy. 2006 to the paper
R&D Systems anti-EG-VEGF (prokineticins) antibody (no. MAB1209) was used in protein and paraffin sections from human prostate, and which were used in western blot and immunohistochemistry, to study the expression of EG-VEGF/PK1 and PK2 and their receptors (PK-R1 and PK-R2) in human prostate and their involvement in cancer.
total:1
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway. 2010 to the paper
Lifespan Biosciences anti-PROKR1 polyclonal antibody was used to perform immunohistochemistry in order to study the modulation of IL11 expression by PROK1 via PROKR1 and the calcineurin/NFAT signalling pathway.
total:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 to the paper
Abcam C2 proteasome antibody was used in western blot in order to demonstrate that increased AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathway more
total:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Santa Cruz Biotechnology anti-Psc3 antibody was used to carry out ChIP assays in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International mouse monoclonal anti-human 20S proteasome subunit alpha4 was used for immunohistochemistry to investigate the effect of immunoproteasome on the Multiple Sclerosis pathogenesis. more
total:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Enzo Life Sciences anti-alpha7 antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:2
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta1 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD). more
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta5 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP7 antibody was used for immunohistochemistry to study the effect of immunoproteasome on the Multiple Sclerosis. more
total:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP2 antibody was used to perform immunohistochemistry to study the role of immunoproteasome in the Multiple Sclerosis pathogenesis. more
total:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 to the paper
Cell Signaling Technology anti-phospho-Ser235/236-S6 antibody was used to perform immunocytochemistry in order to study the capacity of rapamycin to provide neuroprotection in Parkinson disease models. more
total:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 to the paper
New England BioLabs antiphospho-p44/42 MAPK antibody and p44/42 MAPK antibody (PhosphoPlus p44/42 MAPK antibody kit) was used in western blot to study the physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing RhoGEFs.
total:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S2 subunit antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication.
total:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S5a antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication. more
total:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p27 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International rabbit polyclonal anti-PA28alpha antibody was used for immunohistochemistry to determine the role of immunoproteasome in the Multiple Sclerosis. more
total:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 to the paper
BIOMOL anti-proteasome activator 28 subunit beta (PA28beta) antibodoy was used to perform western blot in order to confirm the effect on the expression of proteasome-interacting proteins caused by chronic ethanol feeding.
total:3
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
Santa Cruz Biotechnology rabbit anti-Ptch-1 was used to perform immunocytochemistry in order to show that blood-brain barrier integrity and CNS immune quiescence were promoted by sonic hedgehog pathway. more
total:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Neomarkers PTEN antibody was used to perform immunohistochemistry in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:4
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Cayman Chemicals anti-EP2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:1
Uteroglobin inhibits prostaglandin F2alpha receptor-mediated expression of genes critical for the production of pro-inflammatory lipid mediators. 2005 to the paper
Cayman chemical rabbit polyclonal FP receptor antibody was used in western blot to determine FP protein expression in hUSM cells
total:3
Effect of parathyroid-hormone-related protein on human platelet activation. 2007 to the paper
Santa Cruz Biotechnology affinity-purified mouse monoclonal anti-PTH1R antibody was used in western blot to determine the content of PTH1R in platelets from patients during AMI and patients in the absence of AMI, and Santa Cruz Biotechnology FITC conjugated anti-PTH1R antibody was used in flow cytometry to detect PTH1R expression on the platelet surface obtained from patients during AMI and patients with similar cardiovascular risk factors without AMI. more
total:1
Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function. 2005 to the paper
Exalpha Biologicals anti-RPTP- antibody was used in western blot to study the effect of receptor-type protein-tyrosine phosphatase-kappa on epidermal growth factor receptor function.
total:1
R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6. 2007 to the paper
Covance RSpo1-specific polyclonal antibody was used in western blot to study the regulation of Wnt signaling through inhibiting internalization of LRP6 by R-Spondin1
total:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Millipore anti-Rac1 monoclonal antibody (1:1,000) was used to perform immunoblot in order to study the metastasis suppressed by Rho GDP dissociation inhibitor 2 (RhoGDI2) through Rho GTPases. more
total:3
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. 2009 to the paper
Proteintech Rac2 antibody was used to perform western blot in order to investigate the role of Rac2 in lymphoma progression more
total:3
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Abcam anti-RacGAP antibody was used in immunocytochemistry in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis. more
total:46
MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. 2010 to the paper
Santa Cruz Biotechnology anti-RAF1 antibody was used to perform western blot in order to study the role of microRNA-7 in tongue squamous cell carcinoma cells. more
total:6
Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for proliferation and transformation. 2006 to the paper
Santa Cruz Laboratories anti-Ral A antibody was used in western blot in order to investigate whether the signals generated by Ras proteins were affected by microlocalization and its important biological outcomes. more
total:4
Phosphorylation of RalB is important for bladder cancer cell growth and metastasis. 2010 to the paper
Millipore anti-RalB antibody was used in western blot and immunoprecipitation to investigate the role of phosphorylation of RalB in bladder cancer cell growth and metastasis. more
total:14
Ex vivo expansion of hematopoietic progenitor cells is associated with downregulation of alpha4 integrin- and CXCR4-mediated engraftment in NOD/SCID beta2-microglobulin-null mice. 2009 to the paper
Chemicon anti-alpha5 antibody was used to incubate the human CD34+ cells for 30 minutes at 4- in order to investigate the role of beta4 integrin, alpha5 integrin, and CXCR4 in cytokine-treated human cord blood CD34+ cells. more
total:3
Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels. 2007 to the paper
Santa Cruz Biotechnology anti-EPAC antibody was used in western blot to determine whether the PDE4 sequestered by DISC1 is released after cAMP elevation. more
total:4
An autism-associated variant of Epac2 reveals a role for Ras/Epac2 signaling in controlling basal dendrite maintenance in mice. 2012 to the paper
Santa Cruz anti-Epac2 monoclonal antibody was used to perform coimmunoprecipitations in order to study the role of Epac2 coupleing with Ras signaling in controlling basal dendrite maintenance. more
total:8
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
Cell Signaling anti-raptor was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation. more
total:20
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Oncogene Ras antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:7
p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities. 2009 to the paper
Pierce anti-Ras antibody was used to detect Ras in western blot in order to show the regulation of p120Ras-GAP during its association to the RhoGAP catalytic domain more
total:4
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination. 2010 to the paper
Bethyl anti-RBBP5 antibody was used to carry out ChIP assays in order to investigate the mechanism for PTIP promoting specific chromatin changes and immunoglobulin class-switch recombination. more
total:4
Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation. 2008 to the paper
Santa Cruz aiti-CRBP-1 antibody was used to perform western blot in order to show that differential TGF-beta signaling can activate the stellate cells after liver injury. more
total:5
Poxvirus ankyrin repeat proteins are a unique class of F-box proteins that associate with cellular SCF1 ubiquitin ligase complexes. 2008 to the paper
Lab Vision rabbit-anti-RBX1 antibody was used in western blot in order to identify the poxviral motif as a functional F-box more
total:1
Apolipoprotein c1 association with hepatitis C virus. 2008 to the paper
Anogen mouse monoclonal anti-HCV core protein antibody (MO-I40015B) was used in immunocytochemistry to study the association of apolipoprotein C1 with hepatitis C virus.
total:1
ATM localization and gene expression in the adult mouse eye. 2009 to the paper
Santa Cruz Biotechnology goat polyclonal anti-recoverin antibody was used in immunohistochemistry to incubate with the sections in order to determine the ATM expression patterns and studied its localization.
total:1
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 to the paper
Abcam anti-H3 antibody was used for coimmunoprecipitation in order to illustrate the role of c-Myb in MLL-associated leukemogenesis.
total:2
Differential expression of the regulator of G protein signaling RGS9 protein in nociceptive pathways of different age rats. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal anti-RGS9 antibody (1:100) was used in immunohistochemistry to study the different expression of the regulator of G protein signaling RGS9 protein in nociceptive pathways of different age rats. more
total:2
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase. 2005 to the paper
Santa Cruz Biotechnology anti-Rheb antibody (C-19) was used in western blot to study amino acids mediate mTOR activation by signaling through class 3 PI3K, hVps34. more
total:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoA antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
total:10
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
Santa Cruz Biotechnology anti-RhoB antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:5
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoC antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
total:3
ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth. 2005 to the paper
Upstate anti-Rho antibody was used in western blot to study the regulation of ALS2/Alsin to Rac-PAK signaling and neurite outgrowth. more
total:12
Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos. 2009 to the paper
Abcam mouse anti-rhodopsin antibody was used for western blot in order to investigate the roles of Cep70 and Cep131 in the regulation of ciliogenesis in zebrafish embryos. more
total:8
Clues to CD2-associated protein involvement in cytokinesis. 2005 to the paper
Santa Cruz Biotechnology monoclonal antibody against anti-Rho GDI (A20) was used in western blot to present several clues for the involvement of CD2AP in cytokinesis. more
total:1
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. 2009 to the paper
Proteintech Group Inc polyclonal rabbit anti-RHOT2 antibody was used for western blot in order to investigate the role of Pink1 in the regulation of mitochondrial trafficking.
total:3
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. 2010 to the paper
Cell Signaling Technology anti-rictor antibody was used to carry out western blot analysis in order to investigate the precise contribution of 4E-BPs to mTORC1 signaling. more
total:2
Mass spectroscopic phosphoprotein mapping of Ral binding protein 1 (RalBP1/Rip1/RLIP76). 2007 to the paper
Abnova RalBP1 antibody was used in western blot in order to identify fourteen phosphorylation sites of RalBP1 in human bladder carcinoma UMUC-3 and embryonic kidney derived 293T cells. more
total:1
Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth. 2006 to the paper
Bethyl FLRF/Nrdp1 antibody was used in western blot to study the expression and role of Nrdp1 in cancer.
total:8
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 to the paper
Santa Curz anit-ROCK1 antibody was used to perform western blot to study the different roles of ROCK1 and ROCK2 in regulating keratinocyte adhesion and terminal differentiation. more
total:5
RhoE Is required for keratinocyte differentiation and stratification. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-ROCKII antibody (H-85) was used in western blot to study the role for RhoE in keratinocyte differentiation and stratification more
total:2
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 to the paper
Cell SignalingROR2 antibody was used to perform immunocytochemistry in order to investigate ROR2 mediates Wnt5A signaling in metastatic melanoma. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:36
p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. 2012 to the paper
Cell Signalling anti-S6 (rabbit monoclonal) antibody was used to perform immunoblotting in order to study the effect of p180 on the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. more
total:9
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 to the paper
Cell Signaling anti-phosphorylated p90RSK antibody was used to perform western blot in order to study the important role of GRK4 in D3 receptor's signaling in human proximal tubule cells. more
total:9
Mitogen-activated protein kinase-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection. 2009 to the paper
Santa Cruz anti-RSK2 antibody was used to perform western blot in order to study the role of RSK2 in the cellular antiviral response. more
total:3
Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation. 2009 to the paper
Santa Cruz Biotechnology MSK1 antibody was used in western blot in order to study the role of MSK1 in NF-kB activation and inflammatory diseases more
total:2
Hypoxia-induced energy stress inhibits the mTOR pathway by activating an AMPK/REDD1 signaling axis in head and neck squamous cell carcinoma. 2008 to the paper
Cell Signaling Technology rabbit polyclonal anti-phospho-p70 S6 kinase (Thr389) antibody was used for western blot in order to investigate the role of hypoxia-induced energy stress in the regulation of mTOR pathway in head and neck squamous cell carcinoma1. more
total:2
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Bianca anti-Nogo-A/B antibody was used to perform western blot in order to study synaptic plasticity. more
total:2
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization. 2008 to the paper
Proteintech rabbit anti-RUVBL1 antibody was used for western blot in order to investigate the role of ILK in the regulation of mitotic spindle organization. more
total:23
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
BD anti-mouse S100B antibody (1:1000) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation. more
total:3
Sphingosine 1-phosphate-induced mobilization of intracellular Ca2+ mediates rac activation and adherens junction assembly in endothelial cells. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal Edg-1 antibody was used in western blot to study the mechanism of Rac activation induced by S1P more
total:2
Sphingosine-1-phosphate and the immunosuppressant, FTY720-phosphate, regulate detrusor muscle tone. 2007 to the paper
Exalpha anti-S1P2 antibody was used in western blot to study the role of S1P in overactive bladder syndrome. more
total:1
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Abcam anti-S1PR5 antibody was used to perform cell culture in order to study synaptic plasticity.
total:4
Arrestin competition influences the kinetics and variability of the single-photon responses of mammalian rod photoreceptors. 2009 to the paper
Affinity BioReagent arrestin antibody was used in western blot to investigate the role of arrestin in mammalian rod's single-photon responses more
total:1
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. 2010 to the paper
Cell Signaling Sav1 antibody was used in western blot to investigate the role of hippo signaling in the regulation of mammalian organ size.
total:2
Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. 2009 to the paper
Santa Cruz rabbit polyclonal, goat polyclonal anti-Scribble antiserum (1:500) was used in immunoprecipitation to demonstrate that Hippo signaling is required for normal pronephros development in zebrafish and Scribble participates in it. more
total:2
Syndecan-4 is required for thrombin-induced migration and proliferation in human vascular smooth muscle cells. 2005 to the paper
Seikagaku HSPG neo-epitope (exposed after heparitinase III digestion, clone 3G10) antibody was used in western blot to study thrombin-induced human vascular smooth muscle cell migration and proliferation more
total:1
Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue. 2006 to the paper
Zymed Laboratories rabbit anti syndecan-3 antibody was used in immunohistochemistry to study its expression in human uterine tissue during prolonged labour
total:3
Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans. 2008 to the paper
Santa Cruz Biotechnology anti-syndecan-4 antibody was used in immunocytochemistry to study the effect of heparanase on cell adhesion and spreading. more
total:2
Application of light microscopical and ultrastructural immunohistochemistry in the study of goblet cell carcinoid in the appendix. 2008 to the paper
BioGenex Laboratories rabbit anti-human secretin antibody was used in immunohistochemistry in order to develop a combined histochemical and immunohistochemical procedure to reveal the dual nature of goblet cell carcinoide more
total:1
Secretin-receptor and secretin-receptor-variant expression in gastrinomas: correlation with clinical and tumoral features and secretin and calcium provocative test results. 2007 to the paper
AbD Serotec rabbit anti-secretin receptor polyclonal antibody (1:1000) was used in western blot and immunohistochemistry to study secretin-receptor and secretin-receptor-variant expression in gastrinomas
total:2
Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma. 2007 to the paper
Rockland rabbit anti-SFRP1 polyclonal antibody (600-401-475) antibody was used in western blot (1:100) and in immunohistochemistry (1:300) to study the role of SFRP1 down-regulation in human hepatocellular carcinoma more
total:1
SLAM-associated protein as a potential negative regulator in Trk signaling. 2005 to the paper
BD Biosciences SH2B antibody was used in western blot and immunoprecipitation to study the role of SLAM-associated protein in Trk signaling
total:1
Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo. 2010 to the paper
Abcam anti-human Lnk antibody was used for immunoblotting in order to demonstrate that Lnk leads to stabilization of thrombus development in vivo through regulating integrin alphaIIbbeta3 outside-in signaling in mouse platelets.
total:1
Study of the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma. 2007 to the paper
Santa Cruze SH3GL2 goat polyclonal antibody was used in western blot to study the SH3-study the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma.
total:20
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Cell Signalling anti-ShcA and anti-phospho-ShcA (Tyr239/240) antibodies were used to perform western blot in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
total:16
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Santa Cruz Biotechnology anti-SHP-1 polyclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
total:34
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-Shp2 antibody was used to perform western blot in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
total:8
APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. 2009 to the paper
Zymed mouse monoclonal anti-Skp1 antibody was used in western blot to investigate the regulation of Cdc20 stability during SAC activation in mammalian cells and explore the contribution of spindle checkpoint proteins to Cdc20 stability. more
total:28
Transforming growth factor beta promotes neuronal cell fate of mouse cortical and hippocampal progenitors in vitro and in vivo: identification of Nedd9 as an essential signaling component. 2010 to the paper
Santa Cruz Biotechnology mouse anti-Smad1 antibody was used to carry out immunofluorescence assays in order to investigate the role for transforming growth factor beta in regulating neuronal cell development. more
total:74
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. 2010 to the paper
Cell Signaling anti-Smad2 was used to perform western blot in order to study the roles of RBBP9 as a tumor-associated serine hydrolase to pancreatic neoplasia more
total:51
Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation. 2009 to the paper
Zymed Smad3 polyclonal antibody was used in western blot in order to investigate the role of BMP9 signalling via ALK2/Smad1/Smad4 pathway in ovarian cancer. more
total:21
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. 2008 to the paper
Santa Cruz rabbit anti-Smad4(H-552; 1:1,000) antibody was used to perform western blot in order to study the dynamical regulation of TGF-beta signaling during late lung development in the human and mouse. more
total:11
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-Smad5 antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
total:2
Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells. 2008 to the paper
Cell Signaling Technology anti-Smad6 antibody was used in western blot to elucidate the anti-mitogenic effect of a proteasome inhibitor in relation to BMP signalling in colon cancer. more
total:12
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. 2010 to the paper
Invitrogen anti-Smad7 was used to perform western blot in order to study the roles of RBBP9 as a tumor-associated serine hydrolase to pancreatic neoplasia more
total:5
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-Smad8 antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
total:3
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
Abcam rabbit anti-Smo was used to perform western blot in order to show that blood-brain barrier integrity and CNS immune quiescence were promoted by sonic hedgehog pathway. more
total:11
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Affinity Bioreagents anti-SMRT antibody was used to perform western blot in order to show that IRF5 mediates the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:3
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-Smurf1 antibody was used to carry out western blot analysis and immunohistochemistry assays in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
total:3
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-Smurf2 antibody was used to carry out western blot analysis and immunohistochemistry assays in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
total:5
Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension. 2013 to the paper
Santa Cruz anti-SnoN antibody was used to perform western blot to study the role of BMP-Smad signaling during motor axon extension. more
total:10
Unique early gene expression patterns in human adult-to-adult living donor liver grafts compared to deceased donor grafts. 2009 to the paper
Santa Cruz Biotech SOCS3 antibody was used in immunohistochemistry to study the distinctive differences at the molecular level between deceased donor (DD) and living donor (LD) liver grafts more
total:10
Detection of somatostatin receptors in human osteosarcoma. 2008 to the paper
Dako polyclonal rabbit anti-human somatostatin antibody was used in immunohistochemistry in order to study the role of somatostatin receptors in human osteosarcoma more
total:11
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 to the paper
Santa Cruz rabbit Sos-1 antibody was used in western blot to study the role of Abi-1 in morphogenesis and synapse formation. more
total:1
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis. 2005 to the paper
BD Biosciences anti-SOS-2 antibody was used in western blot to study the role of AIF in nuclear phenotype and DNA degradation during apoptosis
total:70
Sp1 and KLF15 regulate basal transcription of the human LRP5 gene. 2010 to the paper
Santa Cruz anti-Sp1 antibody was used to perform ChIP assay in order to study the regulatory function of Sp1 and KLF15 on basal transcription of the human LRP5 gene. more
total:2
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. 2009 to the paper
Upstate anti-SPRY2 antibody was used for western blot in order to investigate the role of BRAF in the regulation of RAF-MEK signaling pathway. more
total:14
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Santa Cruz anti-p62 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:1
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-srGAP1 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation.
total:1
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. 2008 to the paper
Zymed anti-somatostatin antibody was used to perform western blot and immunohistochemistry in order to study the acinar polarity defects and cystic neoplasms induced by Lkb1-deficient in pancreas.
total:1
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 to the paper
ProteinTech Group STAM-1 polyclonal antibody was used to perform western blot and immunoprecipitation in order to clarify that the arrestin-2/STAM-1 complex modulates CXCR4 lysosomal sorting by ubiquitination of HRS.
total:84
T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response. 2010 to the paper
Santa Cruz Biotechnology anti-STAT1 polyclonal antibody was used to perform immunohistochemistry in order to study the transcriptional features of T-cell/histiocyte-rich large B-cell lymphoma. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:51
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Santa Cruz Biotechnology anti-STAT5 antibody was used to perform immunoprecipitation in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers. more
total:23
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 2009 to the paper
Upstate Biotech-Millipore anti-P-STAT5B (Y699) antibody was used in western blot in order to characterize the role of ERBB4 mutations in melanoma. more
total:15
Regulation of telomerase activity by interferon regulatory factors 4 and 8 in immune cells. 2009 to the paper
Santa Cruz anti-Stat6 antibody was used to perform western blot in order to show that IRF-4 and IRF-8 can increase telomerase activity. more
total:1
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. 2010 to the paper
Cell Signaling Mst2 antibody was used in western blot to investigate the role of hippo signaling in the regulation of mammalian organ size.
total:1
Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis. 2006 to the paper
Cell Signaling Technology rabbit polyclonal antibodies to Mst1 were used in western blot to detect Mst1 in human 293T and U2OS cell lines.
total:1
Absence of gemin5 from SMN complexes in nuclear Cajal bodies. 2007 to the paper
Dr. Glenn E Morris (RJAH Orthopaedic Hospital) rabbit antiserum against unrip was used in western blot and immunocytochemistry to study the absence of gemin5 from SMN complexes in nuclear Cajal bodies
total:2
High affinity choline transporter immunoreactivity in rat ileum myenteric nerves. 2007 to the paper
Santa Cruz goat Substance P antibody (1:50) was used in immunohistochemistry to localize CHT immunoreactivity (CHT-IR) within the rat ileum ENS and determined whether it colocalised with immunoreactivity for markers of cholinergic, tachykinergic, and nitrergic circuitry. more
total:12
Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk.. 2008 to the paper
Santa Cruz Biotech anti-Syk antibody was used to perform western blot in order to study the interaction between NS5A and Syk. more
total:26
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 to the paper
Cell Sciences B-A38 (Syndecan-1) antibody was used in western blot in order to demonstrate that heparanase can promote expression of syndecan-1 in the nucleus. more
total:2
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TAB2 monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:4
Elimination of rat spinal substance P receptor bearing neurons dissociates cardiovascular and nocifensive responses to nicotinic agonists. 2008 to the paper
Chemicon anti-Substance P receptor (NK-1r) (1:1000 of source stock) antibody was used in immunohistochemistry to further characterize intrathecal (IT) delivery of nicotinic agonists. more
total:10
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 to the paper
Santa Cruz mouse anti-Tak1 antibody was used to perform western blotting in order to determine the role of NRAGE in regulating NF-kappaB activity. more
total:10
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Serotec anti-talin antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more
total:2
Thymus and activation regulated chemokines in children with atopic dermatitis: Kyushu University Ishigaki Atopic Dermatitis Study (KIDS). 2007 to the paper
Shionogi murine monoclonal TARC antibody was used in ELISA to investigate the clinical significance of serum thymus and activation-regulated chemokine (TARC) in children with atopic dermatitis (AD). more
total:2
Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen. 2008 to the paper
Santa Cruz Biotechnology affinity-purified polyclonal Tcf-3 antibody was used in immunocytochemistry and western blot in order to demonstrate that integration beta-catenin/Lef-1/Tcf-3 signaling with ERalpha is necessary for estrogen-dependent endogenous gene regulation in uterine biology more
total:6
Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism. 2008 to the paper
Upstate Biotechnology anti-TCF-4 antibody was used in immunoprecipitation and western blotting to investigate the action mechanism of the growth inhibition induced by bis[2-(acylamino)phenyl] disulfide. more
total:1
Zinc status and vacuolar zinc transporters control alkaline phosphatase accumulation and activity in Saccharomyces cerevisiae. 2009 to the paper
Molecular Probes anti-Vph1 was used in western blot to investigate the role of the Zrc1 and Cot1 vacuolar zinc transporters in the regulation of Pho8 protein activity and accumulation.
total:10
The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model. 2010 to the paper
Calbiochem anti-TERT antibody (1:350) was used to perform immunohistochemistry in order to study the function of pAkt on posterior capsule more
total:1
Identification and characterization of novel isoforms of human DP-1: DP-1{alpha} regulates the transcriptional activity of E2F1 as well as cell cycle progression in a dominant-negative manner. 2005 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-DP-1 antibody was used in western blot to identify and Characterize the novel isoforms of human DP-1.
total:35
Noncanonical TGF? signaling contributes to aortic aneurysm progression in Marfan syndrome mice. 2011 to the paper
R&D Systems anti-TGFbeta antibody was used for intraperitoneal injection in order to study the role of transforming growth factor-beta signaling in aortic disease in Marfan syndrome mice. more
total:15
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 to the paper
Santa Cruz Biotechnology anti-TGFBR1 antibody was used to carry out western blot analysis in order to investigate the role for Smurf2 in promoting breast cancer metastasis. more
total:21
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. 2008 to the paper
Santa Cruz rabbit anti-Tgfbr2(C-16; 1:50; used with blocking peptide SC-220P; catalog no. SC-220) antibody was used to perform immunohistochemistry and western blot in order to study the dynamical regulation of TGF-beta signaling during late lung development in the human and mouse. more
total:1
Hepatocyte growth factor receptor signaling mediates the anti-fibrotic action of 9-cis-retinoic acid in glomerular mesangial cells. 2005 to the paper
Santa Cruz Biotechnology anti-TGIF antibody was used in western blot to study the effects of 9-cis-RA on glomerular mesangial cell activation induced by transforming growth factor (TGF) beta1.
total:20
Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. 2009 to the paper
Acbam mouse monoclonal antibody against human and mouse thrombospondin-1 was used in immunohistochemistry to investigate the role of transforming growth factor Beta signaling in the regulation of tumor growth. more
total:1
Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation. 2005 to the paper
Novocastra Laboratories monoclonal anti-TSHr antibody (AA 211 414) was used in immunocytochemistry to study TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy
total:6
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells. 2008 to the paper
Santa Cruz Biotechnology Tiam1 antibody (C-16) was used to perform co-immunoprecipitation analyse and chromatin immunoprecipitation assays in order to demonstrate the mechanism between Rac1 and the canonical Wnt signalling pathway in colorectal cancer cells. more
total:14
PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis. 2009 to the paper
Santa Cruz Biotechnology anti-Tip60 antibody was used in western blot in order to explain that PDCD5 can maintain the histone acetyltransferase activity of the Tip60 protein and promote DNA damage-induced apoptosis as a Tip60 coactivator. more
total:3
EspF Interacts with nucleation-promoting factors to recruit junctional proteins into pedestals for pedestal maturation and disruption of paracellular permeability. 2008 to the paper
Zymed Laboratories rabbit polyclonal anti-ZO-2 antibody was used in western blot and immunocytochemistry to study the role for EspF in pedestal maturation and the disruption of paracellular permeability. more
total:1
Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA-binding protein with broad RNA targets. 2006 to the paper
Minoru S. H. Ko (National Institutes of Health) anti-ESG1 polyclonal antibody was used in western blot and immunohistochemistry to demonstrate that ESG1 is an RNA-binding protein.
total:6
Expression of Toll-like receptors in verruca and molluscum contagiosum. 2008 to the paper
Santa Cruz Biotechnology goat polyclonal anti-human TLR9 was used in immunohistochemistry to study the expression of toll-like receptors in verruca and molluscum contagiosum in cryostat sections from human skin. more
total:1
Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins. 2009 to the paper
Abcam anti-Tankyrase antibody was used to carry out western blot analysis and immunoprecipitation assays in order to find the novel substrates for transcription factor hypoxia-inducible factor in the proteome scale.
total:17
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TRAF6 (H-274) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:4
Hereditary lattice corneal dystrophy is associated with corneal amyloid deposits enclosing C-terminal fragments of keratoepithelin. 2005 to the paper
Dako polyclonal anti-transthyretin antibody was used in immunohistochemistry to study the association of hereditary lattice corneal dystrophy with corneal amyloid deposits enclosing C-terminal fragments of feratoepithelin. more
total:2
Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis. 2008 to the paper
EMD Chemicals anti-TRB3 antibody was used to perform western blot in order to study the response of the mTORC1 signaling after the inhibition of protein synthesis. more
total:1
Cdc42-interacting protein 4 promotes breast cancer cell invasion and formation of invadopodia through activation of N-WASp. 2010 to the paper
Becton Dickson anti-CIP4 antibody was used to perform immunocytochemistry and western blot in order to study the role and contribution of CIP4 in human cancer cell motility and invasion.
total:27
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Upstate anti-TrkA antibody (06-574, 1:100) was used to perform immunostaining in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
total:7
Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice. 2008 to the paper
BD Biosciences mouse anti-TrkB antibody was used in western blot in order to study the pathogenesis of Joubert syndrome and the role of the Ahi1-Hap1 complex in early brain development more
total:6
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC3 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
total:7
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC6 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
total:1
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells. 2005 to the paper
Santa Cruz anti-TRPC7 antibody was used in western blot to study the role of endogenous TRPC6 channels in Ca2+ signal generation.
total:3
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 to the paper
Santa Cruz anti-TRRAP antibody was used in western blot to study the role for the STAGA subunit ADA2b in regulating human GCN5 catalysis. more
total:9
Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression. 2010 to the paper
Zymed Laboratories anti-TSC1 antibody was used to perform western blot and immunoprecipitation in order to study how carboxy terminal tail of polycystin-1 inhibit mTOR via increasing the interaction between TSC2 and TSC1. more
total:26
Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression. 2010 to the paper
Epitomics anti-TSC2 antibody was used to perform western blot and immunoprecipitation in order to study the mechanism by which carboxy terminal tail of polycystin-1 repress mTOR signaling via membrane retention of TSC2. more
total:5
Bone marrow cells produce a novel TSHbeta splice variant that is upregulated in the thyroid following systemic virus infection. 2009 to the paper
Santa Cruz Biotechnology anti-TSHb antibody was used to carry out immunopreciptation assays in order to characterize the function of a novel TSH splice variant during immunological stress. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:1
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes. 2007 to the paper
Boston Biochem anti-UbcH5 antibody was used to perform immunoprecipitation in order to study the roles of the DET1 during the regulation of the Cul4A activity.
total:1
Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. 2010 to the paper
Abcam anti-UbcH5c antibody was used to perform western blot in order to study the mechanism of A20 action in the inhibition of NF-kappaB signaling.
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:1
CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha. 2007 to the paper
Abnova USP15 antibody was used in western blot to demonstrate that CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha.
total:2
Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. 2008 to the paper
Upstate Biotechnology anti Vav3 antibody was used in western blot and immunohistochemistry to study the activation of estrogen receptor by Vav3 oncogene and Vav3 overexpression in human breast cancer more
total:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
Santa Cruz biotechnology anti-VEGF antibody was used for performing immunohistochemistry in order to explore the effect of DLC1 on angiogenesis. more
total:10
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Epitomics anti-VEGF antibody (1:1000) was used in western blot to study the effects of curcumin on the expression of peroxisome proliferator-activated receptor delta (PPARdelta) and related genes in HT-29 cells. more
total:1
Failure to up-regulate VEGF165b in maternal plasma is a first trimester predictive marker for pre-eclampsia. 2009 to the paper
R&D Systems anti-VEGFb antibody was used to quantify the mount of VEGFb by ELISA assays in order to investigate the role for VEGF165b as trimester predictive marker for pre-eclampsia.
total:35
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling.. 2010 to the paper
Santa Cruz anti-Flk-1 antibody was used to perform immunoprecipitation in order to reveal the critical role of prorenin receptor and vacuolar H+-ATPase-mediated acidification in Wnt signaling. more
total:15
Expression of VEGF-C and its receptor VEGFR-3 in the bone marrow of patients with acute myeloid leukaemia. 2008 to the paper
Santa Cruz anti-VEGFR-3 (sc-321) antibody was used to perform immunohistochemistry in order to study the expression of VEGF-C and VEGFR-3 in the acute myeloid leukaemia patients' bone marrow. more
total:32
Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells. 2009 to the paper
Serotec sheep anti-VWF was used to test von Willebrand factor (VWF) in order to research Rab27a and MyRIP's regulation to the amount and multimeric state of VWF released from endothelial cells. more
total:1
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. 2007 to the paper
Dr. Juan S. Bonifacino (National Institute of Child Health and Human Development) Vps29 antibody was used in western blot and immunoprecipitation to study the functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors
total:1
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. 2007 to the paper
Dr. Juan S. Bonifacino (National Institute of Child Health and Human Development) Vps29 antibody was used in western blot and immunoprecipitation to study the functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors
total:1
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. 2007 to the paper
Dr. Juan S. Bonifacino (National Institute of Child Health and Human Development) Vps35 antibody was used in western blot and immunoprecipitation to study the functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors
total:4
WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. 2009 to the paper
Abcam antibodies against WNT1 were used in western blot and immunohistochemistry to investigate the role of WISP1 in the regulation of ATII cell hyperplasia and plasticity. more
total:1
NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation. 2010 to the paper
Santa Cruz Biotechnology anti-Nrf2 antibody was used in immunoprecipitation in order to investigate the role of NF-E2 in the regulation of ROS accumulation and megakaryocytic maturation.
total:1
Functional Wnt signaling is increased in idiopathic pulmonary fibrosis. 2008 to the paper
Zymed Laboratories/Invitrogen Wnt3a antibody was used in immunohistochemistry in order to quantify and localize the expression and activity of the Wnt/beta-catenin pathway in IPF
total:2
Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen. 2008 to the paper
Santa Cruz Biotechnology affinity-purified polyclonal Wnt-4 antibody was used in western blot in order to demonstrate that integration beta-catenin/Lef-1/Tcf-3 signaling with ERalpha is necessary for estrogen-dependent endogenous gene regulation in uterine biology more
total:4
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 to the paper
R&D Wnt5A antibody was used to perform western blot in order to investigate the effection of Wnt5A to ROR2 more
total:1
The p53 transcriptional target gene wnt7b contributes to NGF-inducible neurite outgrowth in neuronal PC12 cells. 2008 to the paper
Santa Cruz Biotechnology wnt7a antibody was used in western blot in order to demonstrate that the transcription factor p53 regulates PC12 neuronal differentiation following NGF treatment
total:1
The p53 transcriptional target gene wnt7b contributes to NGF-inducible neurite outgrowth in neuronal PC12 cells. 2008 to the paper
Santa Cruz Biotechnology wnt7b antibody was used in western blot in order to demonstrate that the transcription factor p53 regulates PC12 neuronal differentiation following NGF treatment
total:1
Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. 2006 to the paper
Santa Cruz anti-WWP1 antibody was used in immunoprecipitation to study regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.
total:28
Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance. 2009 to the paper
R&D systems anti-XIAP antibody was used in western blot to investigate the role of PARP-1 in the NF-kB signalling cascade induced by ionizing radiation more
total:7
Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis. 2009 to the paper
Santa Cruz Biotechnology CRM-1 antibody was used for Western blotting in order to investigate the effect of LKB1 on nucleocytoplasmic transport. more
total:3
Hippo pathway effector Yap is an ovarian cancer oncogene. 2010 to the paper
Santa Cruz Biotechnology anti-Yap antibody was used in western blot and immunohistochemistry to study the effect of the hippo pathway effector Yap on the progression of ovarian cancer. more
total:6
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 to the paper
Upstate rabbit anti-Yes1 (06.514) polyclonal antibody was used to perform western blot and immunocytochemistry in order to investigate the molecular mechanisms underlying CRMP2 function in CXCL12-induced T lymphocyte migration. more
total:1
The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells. 2005 to the paper
Santa Cruz Biotechnology goat anti-SARA (N-20) antibody was used in immunoprecipitation and western blot to study the role of internalization in transforming growth factor 1-induced smad2 association with smad anchor for receptor activation (SARA) and smad2-dependent signaling in human mesangial cells
total:55
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Zymed mouse anti-ZO-1 (1:1,000) antibody was used to perform immunofluorescence in order to study the role for TRAF4, a novel phosphoinositide-binding protein, in modulating tight junctions and promoting cell migration. more