Semaphorin interactions
gene
reagent
sample publication
sample review
total:3
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 to the paper
BD Biosciences anti-p190RhoGAP was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis. more
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
total:30
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. 2009 to the paper
R&D rabbit anti-pMET antibody was used to perform immunohistochemistry in order to study the function of the fixative in the immunohistochemical detection of phosphoproteins. more
total:123
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
Invitrogen biotin-labeled anti-CD45 mAb was used for cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-Cdc42 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation. more
total:8
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 to the paper
Santa Cruz Biotechnology anti-Cdk5 (SC-173), Cdk5-pTyr-15 (SC-12918), and Cdk5-pSer-159 (SC-12919) antibodies were used to perform western blot in order to investigate the molecular mechanisms underlying CRMP2 function in CXCL12-induced T lymphocyte migration. more
total:8
Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion. 2008 to the paper
Alexis Biochemicals polyclonal anti-p23 antibody was used in western blot in order to study the role of acetylation and extra-cellular location of heat shock protein 90alpha in tumor cell invasion more
total:8
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Sigma-Aldrich polyclonal anti-cofilin and anti-phospho-cofilin antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
total:1
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. 2009 to the paper
BD Biosciences-Pharmingen monoclonal anti-Drp1 antibody was used in immunohistochemistry in order to introduce a rapid regulation of mitochondrial dynamics in acute kidney injury.
total:2
Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3. 2009 to the paper
Immuno-Biological Laboratories anti-CRMP-2 antibody was used to perform western blot in order to show that the mutant SOD1 can sequester KAP3 and then reduce the axonal transport of choline acetyltransferase and acetylcholine release. more
total:1
Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits. 2008 to the paper
Chemicon polyclonal rabbit anti-CRMP4/Tuc-4 antibody (Cat:AB5454) was used in immunohistochemistry to study what happens in the cerebellar cortex of peripuberal rabbits by using endogenous and exogenously-administered cell proliferation antigens in association with a cohort of typical markers for neurogenesis.
total:2
A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer. 2006 to the paper
Santa Cruz goat polyclonal antibodies generated against either Fes amino-terminal (Fes N-19) or carboxyl-terminal (Fes C-19) peptides were used in western blot to investigate Fes expression in human 293T cells, as well as HT-29 and HCT 116 cells, and in immunohistochemstry to detect Fes expression in normal adult human colon sections and human colorectal cancer cell line HT-29. more
total:19
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-FYN antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking. more
total:79
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Santa Cruz Biotechnology anti-GSK3 beta antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
total:69
Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. 2008 to the paper
Zymed Laboratories anti-c-erbB-2 antibody was used in immunohistochemistry to investigate the relationship between amphiregulin expression and liver metastases of colorectal cancer. more
total:68
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-HSP90 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:8
Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. 2010 to the paper
Millipore anti-H3S28P antibody was used in western blot in order to investigate the mechanism of how the embryonic stem cells chromatin structure change was regulated by condensin complexes during mitotic progression. more
total:11
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha1 antibody (clone FB12) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
total:4
Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer. 2007 to the paper
Transduction Laboratories anti-LIMK1 antibody was used in western blot and immunohistochemistry to study the role of LIM kinase 1 in reversible G1/S phase arrest, chromosomal instability and prostate cancer. more
total:2
ROCK1 and LIMK2 interact in spread but not blebbing cancer cells. 2008 to the paper
Cell Signalling anti-LIMK2 was used to perform western blot in order to show that ROCK1 could interact with LIMK2 in polarised but not blebbing cancer cells. more
total:4
Internalization of large double-membrane intercellular vesicles by a clathrin-dependent endocytic process. 2007 to the paper
BAbCO anti-nonmuscle myosin-IIB antibody was used in immunocytochemistry in order to investigate the mechanism of large, double-membrane vesicles internalization based on clathrin-dependent endocytosis. more
total:7
Integrin-linked kinase regulates smooth muscle differentiation marker gene expression in airway tissue. 2008 to the paper
Sigma-Aldrich monoclonal anti-human smooth muscle myosin antibody was used for western blot in order to show that ILK can regulate airway smooth muscle differentiation. more
total:3
An adhesion-dependent switch between mechanisms that determine motile cell shape. 2011 to the paper
Abcam polyclonal rabbit anti-myosin(ab2480) antibody was used to perform immunofluorescence in order to study the mechanisms of keratocytes behavior determined by adhesion strength. more
total:3
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. 2009 to the paper
Sigma anti-NMHC-IIA antibody was used to perform western blot in order to study the assemble of mammalian nonmuscle myosin II in live cells. more
total:7
Role of placenta growth factor in malignancy and evidence that an antagonistic PlGF/Flt-1 peptide inhibits the growth and metastasis of human breast cancer xenografts. 2007 to the paper
Santa Cruz Biotechnology NRP-1 antibody was used in western blot and immunohistochemistry to study the role of placenta growth factor in malignancy. more
total:29
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Epitomics rabbit monoclonal anti-Pak1 antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
total:6
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 to the paper
Santa Cruz Biotechnology anti-PAK-2 antibody was used for western blot in order to investigate the role of PAK-2 in the regulation of anticancer drug-induced cell apoptosis. more
total:1
Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice. 2010 to the paper
R&D Systems biotinylated anti-human Plexin D1 antibody was used to perform western blot and immunohistochemistry in order to study the function of sema3E-plexin D1.
total:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Millipore anti-Rac1 monoclonal antibody (1:1,000) was used to perform immunoblot in order to study the metastasis suppressed by Rho GDP dissociation inhibitor 2 (RhoGDI2) through Rho GTPases. more
total:3
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. 2009 to the paper
Proteintech Rac2 antibody was used to perform western blot in order to investigate the role of Rac2 in lymphoma progression more
total:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoA antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
total:10
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
Santa Cruz Biotechnology anti-RhoB antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:5
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoC antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
total:8
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 to the paper
Santa Curz anit-ROCK1 antibody was used to perform western blot to study the different roles of ROCK1 and ROCK2 in regulating keratinocyte adhesion and terminal differentiation. more
total:5
RhoE Is required for keratinocyte differentiation and stratification. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-ROCKII antibody (H-85) was used in western blot to study the role for RhoE in keratinocyte differentiation and stratification more
total:1
Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis. 2007 to the paper
R&D Systems SEMA 7A (AF1835) antibody was used in western blot to study the role of semaphorin 7A in TGF-beta1-induced pulmonary fibrosis
total:10
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Serotec anti-talin antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more