Rho GTPase cycle
gene
reagent
sample publication
sample review
total:1
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Invitrogen rabbit IgG was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models.
total:1
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 to the paper
ABGENT anti-GRAF was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis.
total:3
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 to the paper
BD Biosciences anti-p190RhoGAP was used to perform western blot in order to investigate the role of the tetraspanin TM4SF5 in contact inhibition and tumorigenesis. more
total:3
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Transduction Laboratories p115 antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
total:3
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Spring Bioscience anti-D4-GDI polyclonal antibody (1:1,000) was used to perform immunoblot in order to study the Rho GDP dissociation inhibitor 2 (RhoGDI2) suppressed metastasis through Rho GTPases. more
total:1
GM130-dependent control of Cdc42 activity at the Golgi regulates centrosome organization. 2009 to the paper
Santa Cruz Biotechnology anti-beta-PIX antibody was used in western blot to study the role for GM130-dependent control of Cdc42 activity at the golgi in regulating centrosome organization
total:7
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 to the paper
Cell Signaling Technology anti-pY-BCR-ABL antibody was used to carry out western blot analysis in order to investigate the mechanism for Lyn kinase regulating imatinib sensitivity in chronic myelogenous leukemia cells. more
total:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-Cdc42 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation. more
total:5
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 to the paper
For exploring the effect of DLC1 on angiogenesis, BD Biosciences anti-DLC1 monoclonal antibody was used for performing immunohistochemistry. more
total:2
CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase. 2009 to the paper
Santa Cruz Biotechnology anti-Ect2 antibody was used in western blot in order to study the reguation of the expression of Ect2, MgcRacGAP, and MKLP1 during cell cycle progression more
total:1
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1. 2008 to the paper
Santa Cruz rabbit anti-Dbl antibody was used to perform immunoprecipitation and western blot in order to show that Nm23-H1 negatively regulate cell migration and tumor metastasis by modulating the activity of Dbl1.
total:1
BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity. 2005 to the paper
Genemed anti-myosin IXb antibody made against the C-terminal peptide CSASTESLLEERAVRGAAEE was used in western blot to study the role of BIG1 as a binding partner of myosin IXb to regulate its Rho-GTPase activating protein activity.
total:1
The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. 2009 to the paper
Santa Cruz Biotechnology anti-Net1 antibody was used to carry out western blot analysis in order to investigate the regulation of constitutive Vav3 expression along with cell plasticity and migration by dioxin receptor.
total:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Millipore polyclonal anti-human p85 antibody was used to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:3
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. 2009 to the paper
Proteintech Rac2 antibody was used to perform western blot in order to investigate the role of Rac2 in lymphoma progression more
total:3
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Abcam anti-RacGAP antibody was used in immunocytochemistry in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis. more
total:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoA antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
total:10
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 to the paper
Santa Cruz Biotechnology anti-RhoB antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway. more
total:5
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 to the paper
Santa Cruz anti-RhoC antibody was used to perform immunohistochemistry in order to study the effect of silencing of RhoA and RhoC expression on human colorectal carcinoma growth in vivo. more
total:3
ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth. 2005 to the paper
Upstate anti-Rho antibody was used in western blot to study the regulation of ALS2/Alsin to Rac-PAK signaling and neurite outgrowth. more
total:8
Clues to CD2-associated protein involvement in cytokinesis. 2005 to the paper
Santa Cruz Biotechnology monoclonal antibody against anti-Rho GDI (A20) was used in western blot to present several clues for the involvement of CD2AP in cytokinesis. more
total:1
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. 2009 to the paper
Proteintech Group Inc polyclonal rabbit anti-RHOT2 antibody was used for western blot in order to investigate the role of Pink1 in the regulation of mitochondrial trafficking.
total:2
Mass spectroscopic phosphoprotein mapping of Ral binding protein 1 (RalBP1/Rip1/RLIP76). 2007 to the paper
Abnova RalBP1 antibody was used in western blot in order to identify fourteen phosphorylation sites of RalBP1 in human bladder carcinoma UMUC-3 and embryonic kidney derived 293T cells. more
total:11
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 to the paper
Santa Cruz rabbit Sos-1 antibody was used in western blot to study the role of Abi-1 in morphogenesis and synapse formation. more
total:1
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis. 2005 to the paper
BD Biosciences anti-SOS-2 antibody was used in western blot to study the role of AIF in nuclear phenotype and DNA degradation during apoptosis
total:1
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-srGAP1 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation.
total:6
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells. 2008 to the paper
Santa Cruz Biotechnology Tiam1 antibody (C-16) was used to perform co-immunoprecipitation analyse and chromatin immunoprecipitation assays in order to demonstrate the mechanism between Rac1 and the canonical Wnt signalling pathway in colorectal cancer cells. more
total:1
Cdc42-interacting protein 4 promotes breast cancer cell invasion and formation of invadopodia through activation of N-WASp. 2010 to the paper
Becton Dickson anti-CIP4 antibody was used to perform immunocytochemistry and western blot in order to study the role and contribution of CIP4 in human cancer cell motility and invasion.
total:2
Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. 2008 to the paper
Upstate Biotechnology anti Vav3 antibody was used in western blot and immunohistochemistry to study the activation of estrogen receptor by Vav3 oncogene and Vav3 overexpression in human breast cancer more