Regulation of signaling by CBL
gene
reagent
sample publication
sample review
total:1
Studies of a germinal centre B-cell expressed gene, GCET2, suggest its role as a membrane associated adapter protein. 2007 to the paper
Santa Cruz Biotechnology mouse monoclonal BLNK antibody was used in western blot and immunohistochemistry to demonstrate that GCET2 may be an adaptor protein in GC B cells that transduces signals from GC B-cell membrane to the cytosol via its association with GRB2.
total:13
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 to the paper
Cell Signaling Technology anti-pY774-c-Cbl antibody was used to carry out western blot analysis in order to investigate the mechanism for Lyn kinase regulating imatinib sensitivity in chronic myelogenous leukemia cells. more
total:14
Focal adhesion components are essential for mammalian cell cytokinesis. 2008 to the paper
BD Transduction Laboratories CrkI/II antibody was used to perform western blot in order to study the function of focal adhesion components in mammalian cell cytokinesis. more
total:13
Chemical rescue of a mutant enzyme in living cells. 2006 to the paper
Santa Cruz Biotechnology anti-CrkL antibody was used in western blot to study the protein tyrosine kinase Src R388A mutant rescued in live cells with the use of the small molecule imidazole. more
total:19
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-FYN antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking. more
total:36
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal against Ron antibody was used in western blot in order to demostrate the expression of PAX 5 and the regulation for c-Met transcription in small cell lung cancer. more
total:9
Regulation of p73 by Hck through kinase-dependent and independent mechanisms. 2007 to the paper
Santa Cruz rabbit polyclonal anti-Hck was used to perform western blot and immunoprecipitation and immunocytochemistry in order to show the mechanisms through which Hck regulates p73 function more
total:20
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 to the paper
Santa Cruz anti-Lyn 44 antibody was used to perform western blot in order to study the roles of the lipid raft-dependent Fc secre tRI ubiquitination in the regulation of receptor endocytosis. more
total:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-p110alpha was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:43
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Upstate anti-p85 pAb was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:6
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz polyclonal anti-p110beta antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:5
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz anti-p110delta monoclonal antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Millipore polyclonal anti-human p85 antibody was used to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:12
Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk.. 2008 to the paper
Santa Cruz Biotech anti-Syk antibody was used to perform western blot in order to study the interaction between NS5A and Syk. more
total:6
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 to the paper
Upstate rabbit anti-Yes1 (06.514) polyclonal antibody was used to perform western blot and immunocytochemistry in order to investigate the molecular mechanisms underlying CRMP2 function in CXCL12-induced T lymphocyte migration. more