Regulation of pyruvate dehydrogenase (PDH) complex
gene
reagent
sample publication
sample review
total:2
Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma. 2009 to the paper
Invitrogen mouse monoclonal anti-PDH E1alpha was used to perform western blot in order to show that ROS production and PDK2 upregulation induced by mitochondrial ND2 mutation lead to HIF1alpha accumulation in head and neck squamous cell carcinoma. more
total:1
Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders. 2009 to the paper
Molecular Probes PDHB antibody was used to perform western blot in order to investigate the relations between mitochondrial substrates and neurodegenerative diseases
total:9
Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. 2007 to the paper
Stressgen Bioreagents polyclonal anti-PDK1 antibody was used in western blot to study induction of vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1 by hypoxia-inducible factor 1 and dysregulated c-Myc more
total:1
Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma. 2009 to the paper
Abgent rabbit polyclonal anti-PDK2 was used to perform western blot in order to show that ROS production and PDK2 upregulation induced by mitochondrial ND2 mutation lead to HIF1alpha accumulation in head and neck squamous cell carcinoma.