Regulation of mitotic cell cycle
gene
reagent
sample publication
sample review
AIM-1
aurora kinase B
total:23
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Rockland anti-pT232 Aurora B was used to perform immunocytochemistry in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
ANAPC1
anaphase promoting complex subunit 1
total:1
Meningiomas exhibit loss of heterozygosity of the APC gene. 2008 to the paper
Calbiochem monoclonal mouse anti-human APC-1 antibody (1:50) was used to perform immunohistochemistry in order to study the adenomatous polyposis coli (APC) gene's loss of heterozygosity in meningiomas.
ANAPC7
anaphase promoting complex subunit 7
total:1
Downregulation of the anaphase-promoting complex (APC)7 in invasive ductal carcinomas of the breast and its clinicopathologic relationships. 2005 to the paper
Santa Cruz Biotechnology anti-human APC7 antibody was used in western blot and immunohistochemistry to study the clinical significance and the involvement of APC in tumorigenesis.
AURKA
aurora kinase A
total:15
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. 2011 to the paper
Cell Signaling Technology anti-AURKA monoclonal antibody was used to study its relation between RHAMM by immunobloting. more
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
total:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Zymed Laboratories mouse anti-beta TRCP antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
total:6
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. 2010 to the paper
BD Transduction Laboratories anti-BUB1B antibody was used in western blot in order to investigate the different expression levels of spindle proteins in the testicular germ cell tumors. more
BUB3
BUB3 mitotic checkpoint protein
total:2
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
BD Transduction Laboratories monoclonal anti-BUB3 antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
CCNA1
cyclin A1
total:14
CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase. 2009 to the paper
Santa Cruz Biotechnology anti-cyclin A antibody was used in western blot in order to study the reguation of the expression of Ect2, MgcRacGAP, and MKLP1 during cell cycle progression more
CDC14A
cell division cycle 14A
total:1
Regulation of Spo12 phosphorylation and its essential role in the FEAR network. 2009 to the paper
Santa Cruz goat anti-Cdc14 antibody (1:300 dilution) was used to perform immunofluorescence in order to investigate the regulation of S118 phosphorylation of Spo12 and its essential role for FEAR network function.
Cdc2
cyclin dependent kinase 1
total:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk1 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
CDC20
cell division cycle 20
total:6
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Santa Cruz Biotechnology monoclonal anti-p55CDC antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
CDC27
cell division cycle 27
total:8
Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol. 2010 to the paper
Abcam anti-CDC27 antibody was used to perform western blot in order to study the modulation of intracellular F. tularensis phagosome biogenesis and proliferation. more
CDK2
cyclin dependent kinase 2
total:53
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk2 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
Cul1
cullin 1
total:12
Mediator acts upstream of the transcriptional activator Gal4. 2012 to the paper
Abcam anti-Cul1 mouse monoclonal antibody was used to perform immunoprecipitation in order to study how the Mediator initiated Gal4 transcription. more
cyclin A
cyclin A2
total:39
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Santa Cruz Biotechnology monoclonal anti-cyclin A antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
cyclin B1
total:64
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Thermo Fisher Scientific anti-cyclin B1 monoclonal antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
FZR1
fizzy and cell division cycle 20 related 1
total:2
Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis. 2008 to the paper
Calbiochem Cdh1 antibody was used in western blot in order to study the role of Cdh1/APC in tumorigenesis more
Mad2
mitotic arrest deficient 2 like 1
total:11
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. 2010 to the paper
Immuquest anti-MAD2 antibody was used in western blot in order to investigate the different expression levels of spindle proteins in the testicular germ cell tumors. more
PA200
proteasome activator subunit 4
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal regulator PA200 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
Plk1
polo like kinase 1
total:29
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Plk1 antibody was used to perform immunoprecipitation in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
PSMA1
proteasome 20S subunit alpha 1
total:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 to the paper
Abcam C2 proteasome antibody was used in western blot in order to demonstrate that increased AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathway more
PSMA3
proteasome 20S subunit alpha 3
total:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Santa Cruz Biotechnology anti-Psc3 antibody was used to carry out ChIP assays in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
PSMA4
proteasome 20S subunit alpha 4
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International mouse monoclonal anti-human 20S proteasome subunit alpha4 was used for immunohistochemistry to investigate the effect of immunoproteasome on the Multiple Sclerosis pathogenesis. more
PSMA7
proteasome 20S subunit alpha 7
total:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Enzo Life Sciences anti-alpha7 antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
PSMB1
proteasome 20S subunit beta 1
total:2
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta1 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD). more
PSMB5
proteasome 20S subunit beta 5
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta5 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
PSMB8
proteasome 20S subunit beta 8
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP7 antibody was used for immunohistochemistry to study the effect of immunoproteasome on the Multiple Sclerosis. more
PSMB9
proteasome 20S subunit beta 9
total:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP2 antibody was used to perform immunohistochemistry to study the role of immunoproteasome in the Multiple Sclerosis pathogenesis. more
PSMC4
proteasome 26S subunit, ATPase 4
total:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 to the paper
Cell Signaling Technology anti-phospho-Ser235/236-S6 antibody was used to perform immunocytochemistry in order to study the capacity of rapamycin to provide neuroprotection in Parkinson disease models. more
PSMC6
proteasome 26S subunit, ATPase 6
total:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 to the paper
New England BioLabs antiphospho-p44/42 MAPK antibody and p44/42 MAPK antibody (PhosphoPlus p44/42 MAPK antibody kit) was used in western blot to study the physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing RhoGEFs.
PSMD2
proteasome 26S subunit, non-ATPase 2
total:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S2 subunit antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication.
PSMD4
proteasome 26S subunit, non-ATPase 4
total:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S5a antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication. more
PSMD9
proteasome 26S subunit, non-ATPase 9
total:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p27 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
PSME1
proteasome activator subunit 1
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International rabbit polyclonal anti-PA28alpha antibody was used for immunohistochemistry to determine the role of immunoproteasome in the Multiple Sclerosis. more
PSME2
proteasome activator subunit 2
total:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 to the paper
BIOMOL anti-proteasome activator 28 subunit beta (PA28beta) antibodoy was used to perform western blot in order to confirm the effect on the expression of proteasome-interacting proteins caused by chronic ethanol feeding.
RPS27A
ribosomal protein S27a
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
Skp1
S-phase kinase associated protein 1
total:8
APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. 2009 to the paper
Zymed mouse monoclonal anti-Skp1 antibody was used in western blot to investigate the regulation of Cdc20 stability during SAC activation in mammalian cells and explore the contribution of spindle checkpoint proteins to Cdc20 stability. more
Skp2
S-phase kinase associated protein 2
total:17
Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy. 2009 to the paper
Zymed anti-Skp2 was used in 1:1000 dilution to perform western blot in order to show that CSN plays an important role for cell autophagy in K562 cells. more
UBC
ubiquitin C
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
UBE2C
ubiquitin conjugating enzyme E2 C
total:3
Novel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7. 2009 to the paper
Boston Biochem anti-UbcH10 antibody was used to perform immunohistochemistry in order to study the regulation of ubiquitin-conjugating enzyme H7 in S phase of the cell cycle. more
UBE2D1
ubiquitin conjugating enzyme E2 D1
total:1
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes. 2007 to the paper
Boston Biochem anti-UbcH5 antibody was used to perform immunoprecipitation in order to study the roles of the DET1 during the regulation of the Cul4A activity.
ubiquitin
ubiquitin B
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more