Regulation of insulin secretion
gene
reagent
sample publication
sample review
total:3
Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. 2007 to the paper
Santa Cruz Biotechnology anti-adenylate cyclase antibody was used in western blot to study the role of PDE3B and its interaction with PKB for regulation of specific cAMP pools and signalling pathways by insulin. more
total:7
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Santa Cruz Biotechnology anti-AKAP150 antibody was used in western blot in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
total:1
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav2.1 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels.
total:11
The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. 2010 to the paper
Chemicon anti-CaV1.2 antibody was used to carry out western blot analysis in order to investigate the role for STIM1 in coordinating Voltage- and store-operated calcium channels to generate coherent calcium signals. more
total:3
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav1.3 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels. more
total:1
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav2.3 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels.
total:2
Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r). 2007 to the paper
Abcam GLP-1R antibody was used in western blot to study protein expression of GLP-1R to reveal tissue-specific strain differences in pancreas (congenic>B6) and stomach (B6>congenic). more
total:13
Deletion of the mitochondrial flavoprotein apoptosis inducing factor (AIF) induces beta-cell apoptosis and impairs beta-cell mass. 2009 to the paper
Sigma anti-glucagon antibody was used to perform immunohistochemistry in order to study the role of mitochondrial flavoprotein apoptosis inducing factor. more
total:23
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. 2009 to the paper
Abcam rabbit polyclonal anti-GLUT1 antibody was used to perform immunoblot in order to study the roles of the glucose deprivation during the development of KRAS pathway mutation. more
total:5
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
Abcam rabbit anti-GNAI2 antibody was used to carry out immunoprecipitation assays in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
total:11
Caveolin-1 alters Ca(2+) signal duration through specific interaction with the G alpha q family of G proteins. 2008 to the paper
Santa Cruz rabbit anti-Galphaq antibody was used in immunocytochemistry to study the effect of the interaction between caveolin-1 and the Galphaq family of G proteins on Ca2+ signal duration. more
total:4
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
United States Biological rabbit anti-GNAS antibody was used to carry out immunoprecipitation assays in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
total:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 to the paper
Dr. W. Simonds (NINDK) rabbit anti-VAChT antibody was used in western blot to study the localization and differential interaction of R7 RGS proteins with R7BP and R9AP in neurons of vertebrate retina.
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
total:6
The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1. 2006 to the paper
Santa Cruz Biotechnology polyclonal anti-IQGAP1 antibody was used in human A549 cells and in immunocytochemistry to study the interaction between the receptor protein-tyrosine phosphatase PTP and IQGAP1. more
total:5
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 to the paper
Calbiochem IP3R1 antibody was used in western blot and immunohistochemistry to study the role of molecular alterations in the cerebellum of the PMCA2-null in Purkinje neurons. more
total:2
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. 2005 to the paper
Santa Cruz Biotechnology goat anti-IP3R2 antibody was used in western blot to study the binding of phospholipid scramblase 1 to the promoter region of the inositol 1, 4, 5-triphosphate receptor type 1 more
total:8
Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors. 2007 to the paper
Santa Cruz anti-MARCKS was used to perform western blot in order to show that in tumors the tranlation of some NMD-escape PTC-containing mRNAs could be repressed selectively. more
total:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-PKCAalpha antibody was used in western blot in order to study the function of TMX3 in eye development. more
total:3
Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. 2005 to the paper
Santa Cruz Biotechnology PLC beta2 antibody was used in western blot to study localization of TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells more
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 to the paper
Santa Cruz Biotechnology anti-the catalytic D subunit of PKA antibody C-20 was used in human fibrosarcoma HT1080 cells and in western blot to study the role for tyrosine phosphorylation in full-scale activation of the eIF2alpha RNA-dependent protein kinase. more
total:9
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIalpha was used in immunohistochemistry to detect the PKA subunit RIalpha in human adrenal samples more
total:9
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Santa Cruz Biotechnology anti-PKA RII antibody was used in immunoprecipitation in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
total:3
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIIbeta was used in immunohistochemistry to detect the PKA subunit RIIbeta in human adrenal samples more
total:3
Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels. 2007 to the paper
Santa Cruz Biotechnology anti-EPAC antibody was used in western blot to determine whether the PDE4 sequestered by DISC1 is released after cAMP elevation. more
total:4
An autism-associated variant of Epac2 reveals a role for Ras/Epac2 signaling in controlling basal dendrite maintenance in mice. 2012 to the paper
Santa Cruz anti-Epac2 monoclonal antibody was used to perform coimmunoprecipitations in order to study the role of Epac2 coupleing with Ras signaling in controlling basal dendrite maintenance. more
total:3
Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-ANT antibody was used for western blot in order to investigate the role of Ischaemic preconditioning in the regulation of proteasomal activity and the degradation of PKCdelta during reperfusion. more
total:1
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase. 2007 to the paper
Dr. Douglas C. Wallace (University of California, Irvine) ANT2-specific antiserum was used in western blot to study the regulation of insulin secretion by SIRT4
total:11
Fast vesicle fusion in living cells requires at least three SNARE complexes. 2010 to the paper
Synaptic Systems polyclonal anti-SNAP-25 antibody was used to carry out western blot analysis in order to investigate how many SNARE complexes are required for exocytosis fusion. more
total:11
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-syntaxin-1 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
total:8
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-synaptobrevin-2 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more