Regulation of cholesterol biosynthesis by SREBP (SREBF)
gene
reagent
sample publication
sample review
ACACA
acetyl-CoA carboxylase alpha
total:17
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-ACC1 S79ph antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
fatty acid synthase
total:6
Fatty acid synthase expression in cutaneous melanocytic neoplasms. 2005 to the paper
Immuno-Biological Laboratories anti-fatty acid synthase antibody was used in immunohistochemistry to study expression of fatty acid synthase in cutaneous melanocytic neoplasms. more
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
total:1
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-HMGCR antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism.
IDI1
isopentenyl-diphosphate delta isomerase 1
total:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 to the paper
Protein Tech Group anti-IDI1 antibody was used to perform western blot in order to study the cytotoxicity of timosaponin AIII towards tumor cells.
INSIG1
insulin induced gene 1
total:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 to the paper
Biovision anti-INSIG-1 antibody was used to perform western blot in order to study the cytotoxicity of timosaponin AIII towards tumor cells.
KPNB1
karyopherin subunit beta 1
total:7
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-importin beta antibody (sc-137016) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
MBTPS2
membrane bound transcription factor peptidase, site 2
NF-YA
nuclear transcription factor Y subunit alpha
total:13
Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-NF-YA antibody was used in immunoblot in order to study the role of tuberin and OGG1 in the pathogenesis of angiomyolipoma in TSC patients. more
Ran
RAN, member RAS oncogene family
total:17
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-RAN antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
SAR1B
secretion associated Ras related GTPase 1B
SEC23A
Sec23 homolog A, COPII coat complex component
total:3
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents Sec23 antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
SEC24A
SEC24 homolog A, COPII coat complex component
SEC24B
SEC24 homolog B, COPII coat complex component
SEC24C
SEC24 homolog C, COPII coat complex component
SEC24D
SEC24 homolog D, COPII coat complex component
Sp1
Sp1 transcription factor
total:70
Sp1 and KLF15 regulate basal transcription of the human LRP5 gene. 2010 to the paper
Santa Cruz anti-Sp1 antibody was used to perform ChIP assay in order to study the regulatory function of Sp1 and KLF15 on basal transcription of the human LRP5 gene. more
SREBF2
sterol regulatory element binding transcription factor 2
total:3
Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. 2005 to the paper
Santa Cruz Biotechnology anti-SREBP2 antibody was used in western blot to study the effect of liver X receptor alpha on SREBP1c-mediated Abcd2 expression more
SREBP cleavage activating protein
SREBF chaperone
total:1
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-SCAP antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism.
SREBP-1
sterol regulatory element binding transcription factor 1
total:11
Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. 2009 to the paper
NeoMarkers monoclonal SREBP-1 antibody was used in western blot in order to study the mechanism by which the activation of Wnt/beta-catenin signaling in skeletal muscle cells can improve insulin sensitivity. more
TM7SF2
transmembrane 7 superfamily member 2