Regulation of beta-cell development
gene
reagent
sample publication
sample review
Akt
AKT serine/threonine kinase 1
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
AKT3
AKT serine/threonine kinase 3
total:4
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. 2008 to the paper
Millipore anti-Akt3 was used to perform western blot in order to show that PTEN-null tumors is promoted to autophagy and more sensitive to lysosomotropic agents after Akt inhibition. more
FKHR
forkhead box O1
total:20
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 to the paper
Santa Cruz anti-FKHR antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters. more
glucokinase
total:1
Spermatogenic cell-specific type 1 hexokinase is the predominant hexokinase in sperm. 2008 to the paper
ABGENT anti-GCK(N-term) polyclonal antibody was used to perform immunoblotting in order to study the role of spermatogenic cell-specific type 1 hexokinase(HK1S) in sperm.
HES1
hes family bHLH transcription factor 1
total:3
Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer. 2009 to the paper
Chemicon Hes1 antibody was used in western blot in order to generate monoclonal antibodies to evaluate therapeutic potential of targeting EphA2 in pancreatic tumor. more
HNF1B
HNF1 homeobox B
total:5
HNF-1beta regulates transcription of the PKD modifier gene Kif12. 2009 to the paper
Santa Cruz Biotechnology anti-HNF1B antibody was used for western blot in order to investigate the role of HNF-1beta in the regulation of PKD Modifier Gene Kif12. more
HNF4A
hepatocyte nuclear factor 4 alpha
total:12
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 to the paper
Santa Cruz anti-HNF4 alpha antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters. more
insulin
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
NEUROD1
neuronal differentiation 1
total:6
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 to the paper
Santa Cruz anti-NeuroD1 antibody was used to perform western blot in order to study the roles of the fragile X mental retardation protein during the regulations of the proliferation and differentiation of adult neural stem/progenitor cells. more
NKX2-2
NK2 homeobox 2
total:1
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
Developmental Studies Hybridoma Bank anti-mouse Nkx2.2 antibody (1:50) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation.
NR5A2
nuclear receptor subfamily 5 group A member 2
total:2
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter by nuclear receptors liver receptor homologue-1 and small heterodimer partner: a mechanism for differential regulation of cholesterol synthesis and uptake. 2006 to the paper
Santa Cruz Biotechnology anti-LRH-1 antibody (catalog number SC-25389x) was used in human 293T cells and in ChIP assay to study the effect of nuclear receptors liver receptor homologue-1 and small heterodimer partner on 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter. more
ONECUT1
one cut homeobox 1
total:2
Inherent sexually dimorphic expression of hepatic CYP2C12 correlated with repressed activation of growth hormone-regulated signal transduction in male rats. 2008 to the paper
Santa Cruz Biotechnology HNF-6 antibdoy was used in western blot in order to demonstrate that continuous GH induces CYP2C12 expression by activating Erk1 and Erk2 via the GHR more
PAX4
paired box 4
total:1
PAX4 enhances beta-cell differentiation of human embryonic stem cells. 2008 to the paper
Aviva PAX4 antibody (1:500) was used in western blot in order to study the role of PAX4 in the beta-cell differentiation of human embryonic stem cells
PDX-1
pancreatic and duodenal homeobox 1
total:8
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Santa Cruz Pdx1 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models more
PKLR
pyruvate kinase L/R
total:1
Proteomic analysis of low dose arsenic and ionizing radiation exposure on keratinocytes. 2009 to the paper
Abcam anti-pyruvate kinase antibody was used to perform western blot in order to study the proteomic of the keratinocytes after the treatment of low dose arsenic and ionizing radiation exposure.
PTF1A
pancreas associated transcription factor 1a