RNA Polymerase II Transcription
gene
reagent
sample publication
sample review
ALYREF
Aly/REF export factor
total:2
THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo. 2010 to the paper
Santa Cruz monoclonal antibodies against Aly/THOC4 were used in western blot to investigate the role of THOC5/Fms in the maintenance of hematopoiesis and the regulation of THOC1. more
CCNH
cyclin H
total:3
Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor. 2005 to the paper
Santa Cruz Biotechnology cyclin H antibody was used in western blot to study the role of Dmp1 in Ras-Raf-Arf signaling. more
CCNT1
cyclin T1
total:5
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes. 2008 to the paper
Santa Cruz anti-cyclin T1 antibody was used to perform western blot in order to study the association between ING4 and the activity of NF-kappa B molecules bound with target gene promoters. more
cdk7
cyclin dependent kinase 7
total:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK7 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
cdk9
cyclin dependent kinase 9
total:11
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-CDK9 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
CPSF2
cleavage and polyadenylation specific factor 2
CPSF3
cleavage and polyadenylation specific factor 3
CPSF7
cleavage and polyadenylation specific factor 7
CSTF3
cleavage stimulation factor subunit 3
total:1
Elevated levels of the 64-kDa cleavage stimulatory factor (CstF-64) in lipopolysaccharide-stimulated macrophages influence gene expression and induce alternative poly(A) site selection. 2005 to the paper
Christine Milcarek (University of Pittsburgh) anti-CstF-77 antibody was used in western blot to demonstrate that CstF-64 influence gene expression and induce alternative poly (A) site selection..
ELL
elongation factor for RNA polymerase II
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit
total:3
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-XPD was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit
total:5
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-XPB was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
FCP1
CTD phosphatase subunit 1
total:4
The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. 2013 to the paper
Abcam RNA polymerase II CTD repeat YSPTSPS peptide-phospho S2 antibody was used to perform western blot in order to study the structure and function of the tripartite complex containing P-TEFb,AFF4HIV and HIV Tat. more
GTF2A1
general transcription factor IIA subunit 1
GTF2A2
general transcription factor IIA subunit 2
total:1
Human La is found at RNA polymerase III-transcribed genes in vivo. 2005 to the paper
Santa Cruz Biotechnology TFIIA antibody was used in ChIP assay to study the association of human autoantigen La with pol III-transcribed genes in vivo
GTF2E1
general transcription factor IIE subunit 1
total:2
Identification of novel functional TBP-binding sites and general factor repertoires. 2007 to the paper
Santa Cruz TFIIEa antibody was used in ChIP assay to identify novel functional TBP-binding sites and general factor repertoires. more
GTF2E2
general transcription factor IIE subunit 2
GTF2F1
general transcription factor IIF subunit 1
total:3
Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin. 2009 to the paper
Santa Cruz anti-TFIIF antibody was used to perform ChIP assays in order to study the association between the papillomavirus E2 proteins, the host Brd4 protein and the transcriptionally active cellular genes. more
GTF2F2
general transcription factor IIF subunit 2
GTF2H3
general transcription factor IIH subunit 3
total:1
IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. 2009 to the paper
Santa Cruz Biotechnology TFIIH antibody was used in western blot to study the regulation of aromatase transcription and estrogen biosynthesis in adipose stromal cells (ASCs).
HEAB
cleavage factor polyribonucleotide kinase subunit 1
MAGOH
mago homolog, exon junction complex subunit
total:3
The exon junction complex component Magoh controls brain size by regulating neural stem cell division. 2010 to the paper
Proteintech anti-Magoh antibody was used to perform immunohistochemical assays in order to study the genetic mechanisms of Magoh in controlling brain size. more
MNAT1
MNAT1 component of CDK activating kinase
total:2
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". 2006 to the paper
Santa Cruz monoclonal anti-Mat1 antibody (F-6) was used in human T98G cells and in western blot to study the role for cyclins and CDK "inhibitors" in Thr172 phosphorylation of CDK4. more
NCBP1
nuclear cap binding protein subunit 1
total:2
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Protein-Tech anti-CBP80 antibody was used in western blot in order to investigate the function of surveillance complex associated with ribosome during nonsense-mediated mRNA decay (NMD). more
NCBP2
nuclear cap binding protein subunit 2
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Abgent CBP20 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
NELFA
negative elongation factor complex member A
NELFCD
negative elongation factor complex member C/D
NELFE
negative elongation factor complex member E
NFX1
nuclear transcription factor, X-box binding 1
PCF11
PCF11 cleavage and polyadenylation factor subunit
POLR2B
RNA polymerase II subunit B
total:1
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 to the paper
Santa Cruz anti-the large subunit of RNA polymerases II antibody (N20) was used in western blot to study the role for the STAGA subunit ADA2b in regulating human GCN5 catalysis.
RBM8A
RNA binding motif protein 8A
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Sigma Y14 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
RNA polymerase II
RNA polymerase II subunit A
total:69
RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing. 2011 to the paper
Santa Cruz anti-Rpb1 was used to perform western blot and ChIP assay in order to show that histone mRNA 3 end processing needs the phosphorylation of RNAP II CTD Thr4. more
RNPS1
RNA binding protein with serine rich domain 1
SC35
serine and arginine rich splicing factor 2
total:17
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. 2010 to the paper
Sigma mouse anti-SC35 antibody (1:5000) was used to perform immunofluorescence in order to study knockdown of TDP-43 mediated HDAC6 downregulation. more
SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
total:4
The honey bee epigenomes: differential methylation of brain DNA in queens and workers. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-SmB/B' antibody (sc-271094) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
SNRPD3
small nuclear ribonucleoprotein D3 polypeptide
SNRPE
small nuclear ribonucleoprotein polypeptide E
total:3
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. 2008 to the paper
Santa Cruz Biotechnology mouse monoclonal B-Raf antibody was used in western blot in order to examine the effects of combining a proteasome inhibitor with an HDAC inhibitor in GBM cell lines more
SNRPF
small nuclear ribonucleoprotein polypeptide F
SNRPG
small nuclear ribonucleoprotein polypeptide G
SRp20
serine and arginine rich splicing factor 3
total:4
SRp20 and CUG-BP1 modulate insulin receptor exon 11 alternative splicing. 2009 to the paper
Zymed Laboratory mouse monoclonal anti-SRp20 antibody was used in western blot to study the roles for SRp20 and CUG-BP1 in modulating insulin receptor exon 11 alternative splicing. more
SRRM1
serine and arginine repetitive matrix 1
total:1
Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal anti-SRm160 antibody K15 was used in western blot to study the association of SRm160-containing complexes with cohesin.
SRSF1
serine and arginine rich splicing factor 1
total:4
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Zymed mouse anti-SF2/ASF antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing. more
SRSF11
serine and arginine rich splicing factor 11
SRSF5
serine and arginine rich splicing factor 5
total:4
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 to the paper
Santa Cruz Biotechnology HRS rabbit polyclonal antibody (M-79) was used to perform western blot in order to clarify that the arrestin-2/STAM-1 complex modulates CXCR4 lysosomal sorting by ubiquitination of HRS. more
SRSF7
serine and arginine rich splicing factor 7
total:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
BD Bioscience mouse anti-9G8 antibody was used to perform immunoprecipitation in order to study the elongation of RNA Polymerase II during co-transcriptional splicing.
SRSF9
serine and arginine rich splicing factor 9
SSRP1
structure specific recognition protein 1
total:2
FACT facilitates chromatin transcription by RNA polymerases I and III. 2009 to the paper
Abcam anti-SSRP1 was used to perform immunoprecipitation in order to to determine whether indeed FACT associates with Pol I complexes. more
SUPT4H1
SPT4 homolog, DSIF elongation factor subunit
SUPT5H
SPT5 homolog, DSIF elongation factor subunit
total:2
Transcription termination factor Pcf11 limits the processivity of Pol II on an HIV provirus to repress gene expression. 2007 to the paper
Santa Cruz Biotechnology anti-Spt5 (sc-28678) antibody was used in western blot to study the role of transcription termination factor Pcf11 on the processivity of Pol II more
TAF1
TATA-box binding protein associated factor 1
total:7
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-TAF1 antibody was used to perform Chip in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
TAF10
TATA-box binding protein associated factor 10
total:2
SUMOylation inhibits SF-1 activity by reducing CDK7-mediated serine 203 phosphorylation. 2009 to the paper
Upstate Biochemistry amti-RNA polymerase II antibody was used for immunoprecipitation in order to indicate that SUMOylation is mediated through reduced CDK7-induced phosphorylation of SF-1. more
TAF11
TATA-box binding protein associated factor 11
total:2
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-TAF11 antibody was used to perform Chip or Web in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
TAF12
TATA-box binding protein associated factor 12
total:2
Identification of novel functional TBP-binding sites and general factor repertoires. 2007 to the paper
Irwin Davidson TAF12 antibody was used in ChIP assay to identify novel functional TBP-binding sites and general factor repertoires. more
TAF13
TATA-box binding protein associated factor 13
TAF4
TATA-box binding protein associated factor 4
total:1
Identification of novel functional TBP-binding sites and general factor repertoires. 2007 to the paper
Irwin Davidson TAF4 antibody was used in ChIP assay to identify novel functional TBP-binding sites and general factor repertoires.
TAF5
TATA-box binding protein associated factor 5
total:1
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Sigma-Aldrich anti-TAF5 antibody was used to perform Chip in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters.
TAF6
TATA-box binding protein associated factor 6
TAF9
TATA-box binding protein associated factor 9
total:1
Core promoter binding by histone-like TAF complexes. 2005 to the paper
Santa Cruz Biotechnology anti-TAF9 antibody was used in western blot, immunoprecipitation, and EMSA to study histone-like TAF complexes
TAFII105
TATA-box binding protein associated factor 4b
TBP
TATA-box binding protein
total:14
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. 2012 to the paper
Santa Cruz anti-TBP antibody was used to perform Chip or Web in order to show that in human embryonic stem cells there are non-canonical TAF complexes regulate active promoters. more
ELOB
elongin B
total:4
Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome. 2008 to the paper
Santa Cruz anti-Elongin B antibody was used in immunoprecipitation in order to demonstrate that SAP130 may link CRL mediated ubiquitination to gene expression. more
TFIIB
general transcription factor IIB
total:8
Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin. 2009 to the paper
Santa Cruz anti-TFIIB antibody was used to perform ChIP assays in order to study the association between the papillomavirus E2 proteins, the host Brd4 protein and the transcriptionally active cellular genes. more
U2AF1
U2 small nuclear RNA auxiliary factor 1
U2AF2
U2 small nuclear RNA auxiliary factor 2
total:2
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Abcam rabbit anti-U2AF65 antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing. more
UPF3B
UPF3B regulator of nonsense mediated mRNA decay