Purine metabolism
gene
reagent
sample publication
sample review
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
catalase
total:8
Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma. 2009 to the paper
Calbiochem rabbit polyclonal anti-catalase was used to perform western blot in order to show that ROS production and PDK2 upregulation induced by mitochondrial ND2 mutation lead to HIF1alpha accumulation in head and neck squamous cell carcinoma. more
CD73
5'-nucleotidase ecto
total:12
Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. 2010 to the paper
Hycult Biotechnology mouse anti-human CD73 (1:50) antibody was used to perform immunohistochemistry in order to show that the adenosine metabolism and signaling in the lungs of patients with COPD and IPF are altered. more
deoxycytidine kinase
total:3
Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity. 2009 to the paper
Abgent rabbit anti-DCK was used to perform western blot in order to show that resistance to cytarabine arabinoside is associated with population-specific genetic variants. more
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GPX1
glutathione peroxidase 1
total:3
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. 2009 to the paper
Affinity BioReagents ATP synthase antibody was used for western blot in order to investigate the role of mitochondria in endothelial cell dysfunction. more
HPRT1
hypoxanthine phosphoribosyltransferase 1
total:1
The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 2009 to the paper
Abcam anti-HPRT antibody was used to perform western blot in order to study the role of Nedd4 plays in the biological process of muscle breakdown.
PAICS
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
PFAS
phosphoribosylformylglycinamidine synthase