Protein-tyrosine-phosphatase
gene
reagent
sample publication
sample review
total:123
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
Invitrogen biotin-labeled anti-CD45 mAb was used for cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:1
Regulation of Spo12 phosphorylation and its essential role in the FEAR network. 2009 to the paper
Santa Cruz goat anti-Cdc14 antibody (1:300 dilution) was used to perform immunofluorescence in order to investigate the regulation of S118 phosphorylation of Spo12 and its essential role for FEAR network function.
total:10
Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. 2009 to the paper
Santa Cruz Biotechnology anti-Cdc25A antibody was used in western blot in order to study the role of TRAIL for activation of DNA damage response pathways with histone H2AX and Chk2 phosphorylations. more
total:1
Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. 2005 to the paper
BD Biosciences mouse anti-Cdc25B antibody was used in western blot to study the function of forkhead box M1 to regulate the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase.
total:20
Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growth.. 2008 to the paper
Epitomics anti-ATM antibody was used for western blot in order to investigate the role of Chk2 in the regulation of HSV-1 ICP0-mediated G2/M arrest and virus growth more
total:1
Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells. 2010 to the paper
Abcam anti-DUSP12 antibody(1:4,000) was used to perform western blot in order to study the recognition of CML Progenitor Cells expressed antigens by Efficacious Immune Therapy in Chronic Myelogenous Leukemia (CML).
total:1
Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase. 2009 to the paper
BD Biosciences FITC-conjugated anti-human PAC-1 mouse monoclonal antibody was used to carry out flow cytometry analysis in order to investigate the functionality of platelet TLR2 in the immune and inflammatory response.
total:1
Studies of a germinal centre B-cell expressed gene, GCET2, suggest its role as a membrane associated adapter protein. 2007 to the paper
Upstate mouse anti-phospho-tyrosine antibody was used in western blot and immunohistochemistry to demonstrate that GCET2 may be an adaptor protein in GC B cells that transduces signals from GC B-cell membrane to the cytosol via its association with GRB2.
total:3
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. 2009 to the paper
Santa Cruz anti-DUSP4 antibody was used for western blot in order to investigate the role of BRAF in the regulation of RAF-MEK signaling pathway. more
total:6
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-MKP3 antibody was used to perform flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:1
Tissue-specific regulation of the mouse alphaA-crystallin gene in lens via recruitment of Pax6 and c-Maf to its promoter. 2005 to the paper
Santa Cruz Biotechnology anti-Eya1 antibody was used in ChIP assay to study the molecular mechanism of gene activation and repression by Pax6 in mouse alphaTN4-1 cells.
total:17
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors. 2010 to the paper
Santa Cruz Biotechnology anti-MKP-1 antibody was used to perform immunohistochemistry in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors. more
total:1
The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 2009 to the paper
Abgent anti-MTMR4 antibody was used to perform western blot in order to study the role of Nedd4 plays in the biological process of muscle breakdown.
total:1
Cellular localization of Y-box binding protein 1 in brain tissue of rats, macaques, and humans. 2009 to the paper
Santa Cruz Biotechnology polyclonal goat anti-Pgp antibody was used to carry out immunofluorescence assays in order to investigate the cellular localization of YB-1 protein in adult brain of rats, macaques, and humans.
total:29
Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice. 2010 to the paper
Upstate anti-phosphotyrosine antibody was used to perform western blot and immunohistochemistry in order to study the function of sema3E-plexin D1. more
total:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Neomarkers PTEN antibody was used to perform immunohistochemistry in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:1
Ptpmeg is required for the proper establishment and maintenance of axon projections in the central brain of Drosophila. 2007 to the paper
Covance Ptpmeg antibody was used in western blot and immunohistochemistry to study the role of ptpmeg in the regulation of cell-cell signaling events that control the behavior of these axons.
total:3
Identification of a filamin docking site on PTP-PEST. 2006 to the paper
Exalpha Biologicals monoclonal antibody against PTP-PEST was used in immunocytochemistry to detect PTP-PEST expression in HeLa cells more
total:2
MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA. 2010 to the paper
R&D Systems anti-PTPN2 antibody was used for western blot in order to investigate the roles of MDA5 and PTPN2 in the regulation of pancreatic cell responses to the viral by-product double-stranded RNA. more
total:1
The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters. 2008 to the paper
Upstate Biotechnology anti-STEP tyrosine phosphatase monoclonal antobody was used in western blot in order to study the function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters
total:5
Functional comparison of long and short splice forms of RPTPbeta: implications for glioblastoma treatment. 2005 to the paper
Zymed Laboratories custom-made rabbit polyclonal antibody directed against RPTP beta splice junction (CTQPVYNEASNSSHES) was used in western blot and immunohistochemistry to study functional difference between long and short splice forms of RPTPbeta and its implications for glioblastoma treatment. more
total:1
The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters. 2008 to the paper
BD Biosciences protein tyrosine phosphatase antibody kit was used in western blot in order to study the function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters
total:1
The dense core transmembrane vesicle protein IA-2 is a regulator of vesicle number and insulin secretion. 2005 to the paper
GenWay anti-IA-2 beta polyclonal antibody was used in western blot to study the effect of dense core transmembrane vesicle protein IA-2 on vesicle number and insulin secretion
total:1
Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. 2011 to the paper
R&D Systems anti-RPTP sigma antibody was used to perform immunocytochemistry in order to study the role of receptor protein tyrosine phosphatase sigma in sensory neuron extension.
total:1
Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function. 2005 to the paper
Exalpha Biologicals anti-RPTP- antibody was used in western blot to study the effect of receptor-type protein-tyrosine phosphatase-kappa on epidermal growth factor receptor function.
total:1
Receptor type protein tyrosine phosphatase zeta-pleiotrophin signaling controls endocytic trafficking of DNER that regulates neuritogenesis. 2008 to the paper
BD Bioscience anti-PTPzeta was used in immunohistochemistry at 1:40 in order to study the functional interaction between PTPzeta and DNER
total:16
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Santa Cruz Biotechnology anti-SHP-1 polyclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
total:34
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-Shp2 antibody was used to perform western blot in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
total:1
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. 2008 to the paper
Cell Signaling Technology rabbit polyclonal phospho-p70S60K antibody was used in western blot in order to examine the effects of combining a proteasome inhibitor with an HDAC inhibitor in GBM cell lines