Protein-serine/threonine phosphatase
gene
reagent
sample publication
sample review
total:1
Regulation of Spo12 phosphorylation and its essential role in the FEAR network. 2009 to the paper
Santa Cruz goat anti-Cdc14 antibody (1:300 dilution) was used to perform immunofluorescence in order to investigate the regulation of S118 phosphorylation of Spo12 and its essential role for FEAR network function.
total:1
Role of RAD51C and XRCC3 in genetic recombination and DNA repair. 2007 to the paper
Dr. Stephen C. West (London Research Institute) monoclonal (10G11) and polyclonal (SWE36) SCP3 antibodies (raised against denatured full-length hamster SCP3 protein) were used in immunocytochemistry (10G11) and ChIP assay (SWE36) on mouse testicular cells to study the role of RAD51C and XRCC3 in genetic recombination and DNA repair
total:1
Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells. 2010 to the paper
Abcam anti-DUSP12 antibody(1:4,000) was used to perform western blot in order to study the recognition of CML Progenitor Cells expressed antigens by Efficacious Immune Therapy in Chronic Myelogenous Leukemia (CML).
total:1
Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase. 2009 to the paper
BD Biosciences FITC-conjugated anti-human PAC-1 mouse monoclonal antibody was used to carry out flow cytometry analysis in order to investigate the functionality of platelet TLR2 in the immune and inflammatory response.
total:1
Studies of a germinal centre B-cell expressed gene, GCET2, suggest its role as a membrane associated adapter protein. 2007 to the paper
Upstate mouse anti-phospho-tyrosine antibody was used in western blot and immunohistochemistry to demonstrate that GCET2 may be an adaptor protein in GC B cells that transduces signals from GC B-cell membrane to the cytosol via its association with GRB2.
total:3
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. 2009 to the paper
Santa Cruz anti-DUSP4 antibody was used for western blot in order to investigate the role of BRAF in the regulation of RAF-MEK signaling pathway. more
total:6
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-MKP3 antibody was used to perform flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:1
Tissue-specific regulation of the mouse alphaA-crystallin gene in lens via recruitment of Pax6 and c-Maf to its promoter. 2005 to the paper
Santa Cruz Biotechnology anti-Eya1 antibody was used in ChIP assay to study the molecular mechanism of gene activation and repression by Pax6 in mouse alphaTN4-1 cells.
total:4
The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. 2013 to the paper
Abcam RNA polymerase II CTD repeat YSPTSPS peptide-phospho S2 antibody was used to perform western blot in order to study the structure and function of the tripartite complex containing P-TEFb,AFF4HIV and HIV Tat. more
total:17
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors. 2010 to the paper
Santa Cruz Biotechnology anti-MKP-1 antibody was used to perform immunohistochemistry in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors. more
total:19
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. 2008 to the paper
Santa Cruz anti-PP1alpha was used to perform western blot in order to show that SRC-3/AIB1 coactivator function and turnover is regulated by essential phosphatases and a phospho-degron of SRC-3/AIB1 is primary determinants of its turnover. more
total:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate monoclonal anti-PP2Ac antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:1
Role for protein phosphatase 2A in the regulation of Calu-3 epithelial Na+-K+-2Cl-, type 1 co-transport function. 2005 to the paper
Abgent rabbit polyclonal SPAK antibody was used in western blot and immunoprecipitation to study phosphorylation-dependent NKCC1 activity regulation in epithelia
total:1
A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. 2007 to the paper
Abgent anti-PP2Cm antibody(Catalog #:DC13389) was used to perform western blot assays in order to study the molecular mechanisms of PP2Cm in cell apoptosis and MPTP opening regulation.
total:2
Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma. 2007 to the paper
Santa Cruz Biotechnology goat polyclonal PP1 gamma C antibody was used in western blot to study the regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma more
total:4
Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis. 2009 to the paper
Sigma-Aldrich anti-calcineurin A antibody was used in western blot in order to deduce that calcineurin activity and apoptosis of leukemic lymphocytes can be modulated by GC-mediated upregulation of RCAN1-1. more
total:2
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. 2005 to the paper
Chemicon rabbit anti-calcineurin antibody was used in immunohistochemistry to study the mechanisms that trigger astrocyte activation. more
total:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Neomarkers PTEN antibody was used to perform immunohistochemistry in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more