Processing and activation of SUMO
gene
reagent
sample publication
sample review
SAE1
SUMO1 activating enzyme subunit 1
total:2
Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone. 2006 to the paper
Abcam anti-SAE1(ab5645) antibody was used to perform western blot in order to study the process of cAMP signaling induced dynamic changes in the SUMO pathway determine the endometrial response to progesterone. more
SENP1
SUMO specific peptidase 1
total:3
Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts. 2007 to the paper
Abgent polyclonal anti-SENP1 antibody was used to perform western blot in order to study the regulation of Fas-induced apoptosis by SUMO-1 more
SENP2
SUMO specific peptidase 2
total:2
Nitric oxide destabilizes Pias3 and regulates sumoylation. 2007 to the paper
Santa Cruz polyclonal anti-Senp2 was used to perform western blot in order to show that global sumoylation and Pias3 stabilization could be regulated by nitric oxide. more
SENP5
SUMO specific peptidase 5
SUMO-1
small ubiquitin like modifier 1
total:40
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Abcam anti-SUMO1 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
SUMO2
small ubiquitin like modifier 2
total:7
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Abcam anti-SUMO2/3 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
SUMO3
small ubiquitin like modifier 3
total:1
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein. 2006 to the paper
Zymed Laboratories anti-SUMO3 antibody was used in western blot to detect SUMO3 in HEK293 cells co-transfected with His-SUMO isoforms (SUMO1, SUMO2, and SUMO3) and full-length human tau or alpha-synuclein.
UBA2
ubiquitin like modifier activating enzyme 2
total:2
Nitric oxide destabilizes Pias3 and regulates sumoylation. 2007 to the paper
BD Pharmingin monoclonal anti-Uba2 was used to perform western blot in order to show that global sumoylation and Pias3 stabilization could be regulated by nitric oxide. more
UBE2I
ubiquitin conjugating enzyme E2 I
total:10
The forkhead transcription factor Foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity. 2010 to the paper
Santa Cruz anti-UBC9 antibody was used in western blot in order to find the counterpart of forkhead transcription factor- FOXL2 and elucidate the role of its sumoylation more