Potassium channels
gene
reagent
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sample review
Kv1.1
potassium voltage-gated channel subfamily A member 1
total:4
A missense mutation in the Kv1.1 voltage-gated potassium channel-encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemia. 2009 to the paper
NeuroMab mouse monoclonal anti-Kv1.1 antibody was used in western blot to study the association of missense mutation in the Kv1.1 voltage-gated potassium channel-encoding gene KCNA1 with human autosomal dominant hypomagnesemia in HEK293 cells. more
Kv1.3
potassium voltage-gated channel subfamily A member 3
total:6
Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1. 2008 to the paper
Sigma FLAG antibody (1:1000) was used to perform western blot in order to study the funtion of phosphorylation of gamma-binding domain of IkB kinase beta. more
KCNA4
potassium voltage-gated channel subfamily A member 4
total:3
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. 2006 to the paper
Chemicon Kv1.4 antibody (1:500) was used in western blot to demonstrate that dendritic A-type K+ channels regulate action potential backpropagation and the induction of specific forms of synaptic plasticity. more
KCNA5
potassium voltage-gated channel subfamily A member 5
total:3
Rab-GTPase-dependent endocytic recycling of Kv1.5 in atrial myocytes. 2007 to the paper
Chemicon polyclonal anti-Kv1.5 antibody was used in western blot to detect untagged Kv1.5 in human HL-1 cells more
KCNA10
potassium voltage-gated channel subfamily A member 10
KCNAB1
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
KCNC4
potassium voltage-gated channel subfamily C member 4
total:1
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. 2006 to the paper
Chemicon Kv3.4 antibody (1:200) was used in western blot to demonstrate that dendritic A-type K+ channels regulate action potential backpropagation and the induction of specific forms of synaptic plasticity.
KCND1
potassium voltage-gated channel subfamily D member 1
total:1
Orphan glutamate receptor delta1 subunit required for high-frequency hearing. 2007 to the paper
Sigma Kv4.1 antibody was used in immunohistochemistry to study the function of the orphan glutamate receptor delta subunits.
Kv4.2
potassium voltage-gated channel subfamily D member 2
total:2
Regulation of Kv1 channel trafficking by the mamba snake neurotoxin dendrotoxin K. 2007 to the paper
NeuroMab mouse monoclonal anti-Kv4.2 antibody was used in western blot to study the role of snake dendrotoxins (DTX) in regulation of Kv1 channel trafficking. more
Kv4.3
potassium voltage-gated channel subfamily D member 3
total:3
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. 2006 to the paper
Chemicon Kv4.3 antibody (1:500) was used in western blot to demonstrate that dendritic A-type K+ channels regulate action potential backpropagation and the induction of specific forms of synaptic plasticity. more
KCNE5
potassium voltage-gated channel subfamily E regulatory subunit 5
KCNE3
potassium voltage-gated channel subfamily E regulatory subunit 3
KCNF1
potassium voltage-gated channel modifier subfamily F member 1
total:1
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. 2010 to the paper
BD Biosciences anti-Thy 1.1 antibody was used in flow cytometry in order to investigate the roles of Fas ligand and TRAIL in the regulation of murine thymic graft-versus-host disease.
KCNG2
potassium voltage-gated channel modifier subfamily G member 2
KCNG4
potassium voltage-gated channel modifier subfamily G member 4
HERG
potassium voltage-gated channel subfamily H member 2
total:6
Silencing of herg gene by shRNA inhibits SH-SY5Y cell growth in vitro and in vivo. 2008 to the paper
Santa Cruz anti-HERG antibody (sc-15968, 1:1000) was used to perform western blot in order to study the important role of herg in regulating the growth and proliferation of SH-SY5Y cells. more
KCNH8
potassium voltage-gated channel subfamily H member 8
total:1
Rev7/MAD2B links c-Jun N-terminal protein kinase pathway signaling to activation of the transcription factor Elk-1. 2007 to the paper
Cell Signaling anti-phospho-Elk antibody was used to perform western blot in order to show that the Rev7/MAD2B links c-Jun N-terminal protein kinase pathway signaling can activate the transcription factor Elk-1.
KCNJ2
potassium inwardly rectifying channel subfamily J member 2
total:2
Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir2.3 channels in HEK293 cells. 2007 to the paper
Alomone Labs anti-Kir2.1 antibody diluted to 1:2000 was used in western blot to study the role of Kir2.3 isoform in modifying channel sensitivity to pH in heterotetrameric channels. more
KCNJ3
potassium inwardly rectifying channel subfamily J member 3
total:7
Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network. 2010 to the paper
Abcam KCNJ3/GIRK1 antibody(ab61191) was used to perform immunofluorescence in order to study transcriptional and epigenetic mechanisms of Wilms tumor. more
KCNJ4
potassium inwardly rectifying channel subfamily J member 4
total:2
Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir2.3 channels in HEK293 cells. 2007 to the paper
Alomone Labs anti-Kir2.3 antibody diluted to 1:2000 was used in western blot to study the role of Kir2.3 isoform in modifying channel sensitivity to pH in heterotetrameric channels. more
KCNJ5
potassium inwardly rectifying channel subfamily J member 5
total:1
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension. 2011 to the paper
Sigma antibody polyclonal anti-KCNJ5 antibody was used to perform immunohistochemistry and western blot in order to study the expression of KCNJ5 in adrenal glomerulosa.
KCNJ6
potassium inwardly rectifying channel subfamily J member 6
total:5
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
BD Biosciences anti-Bir1 antibody was used to carry out ChIP assays in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
Kir4.1
potassium inwardly rectifying channel subfamily J member 10
total:5
MLC1 is associated with the dystrophin-glycoprotein complex at astrocytic endfeet. 2007 to the paper
USBiological polyclonal antibody against Kir4.1 was used in immunoprecipitation and western blot to isolate and detect Kir4.1 in human brain lysates, and in immunohistochemistry to detect aquaporin-4 distribution in human brain tissues and human glioblastoma multiforme tissues from MLC patients more
TREK
potassium two pore domain channel subfamily K member 2
total:1
Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels. 2005 to the paper
Alomone Labs polyclonal anti-TREK-1 antibody was used in western blot to study the inhibition of TREK-1 background potassium channels which was induced by sequential phosphorylation mediates receptor- and kinase.
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
total:3
Mice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss. 2007 to the paper
Alomone large conductance voltage and bk channel alpha-subunit antibody (1:100) was used in immunohistochemistry to study the physiological function and the contribution of type II transmembrane serine protease to the auditory function. more
KCNMB1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
KCNMB2
potassium calcium-activated channel subfamily M regulatory beta subunit 2
KCNMB3
potassium calcium-activated channel subfamily M regulatory beta subunit 3
KCNMB4
potassium calcium-activated channel subfamily M regulatory beta subunit 4
KCNN2
potassium calcium-activated channel subfamily N member 2
total:1
Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons. 2007 to the paper
Sigma Aldrich rabbit polyclonal SK2 antibody was used in immunocytochemistry to study the involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons.
KCNQ1
potassium voltage-gated channel subfamily Q member 1
total:2
Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines. 2009 to the paper
Santa Cruz goat anti-Q1 antibody was used to perform western blot in order to locate KCNE1 relative to KCNQ1 in the potassium channel. more
KCNQ2
potassium voltage-gated channel subfamily Q member 2
total:2
Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons. 2006 to the paper
Chemicon KCNQ2 antibody was used in western blot to study the role of Kv7/KCNQ/M channels in the control of cell excitability. more
KCNQ3
potassium voltage-gated channel subfamily Q member 3
total:1
Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons. 2006 to the paper
Chemicon KCNQ3 antibody was used in western blot to study the role of Kv7/KCNQ/M channels in the control of cell excitability.
KCNS1
potassium voltage-gated channel modifier subfamily S member 1
KCNS2
potassium voltage-gated channel modifier subfamily S member 2
KCNS3
potassium voltage-gated channel modifier subfamily S member 3
KCNU1
potassium calcium-activated channel subfamily U member 1
KCNV2
potassium voltage-gated channel modifier subfamily V member 2