Post-translational protein modification
gene
reagent
sample publication
sample review
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
total:2
Vascular endothelial growth factor upregulates expression of ADAMTS1 in endothelial cells through protein kinase C signaling. 2006 to the paper
Sigma Chemical abbit polyclonal C-terminal of human anti ADAMTS1 antibody was used in western blot to study the regulation of ADAMTS1 expression in endothelial cells by vascular endothelial growth factor (VEGF). more
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif 10
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif 12
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif 13
total:1
Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion. 2008 to the paper
Santa Cruz Biotechnology TTP antibody was used in immunocytochemistry in order to study the mechanism of persistent translation arrest
ADAMTS14
ADAM metallopeptidase with thrombospondin type 1 motif 14
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif 15
ADAMTS16
ADAM metallopeptidase with thrombospondin type 1 motif 16
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif 17
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif 18
ADAMTS19
ADAM metallopeptidase with thrombospondin type 1 motif 19
ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif 2
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif 3
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4
total:1
The regulation of aggrecanase ADAMTS-4 expression in human Achilles tendon and tendon-derived cells. 2008 to the paper
Serotec ADAMTS-4 were used in western blot in order to study the effects of growth factors on the regulation of ADAMTS-4 expression
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif 6
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif 8
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif 9
ALG1
ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase
ALG10B
ALG10 alpha-1,2-glucosyltransferase B
ALG11
ALG11 alpha-1,2-mannosyltransferase
ALG13
ALG13 UDP-N-acetylglucosaminyltransferase subunit
ALG14
ALG14 UDP-N-acetylglucosaminyltransferase subunit
ALG2
ALG2 alpha-1,3/1,6-mannosyltransferase
ALG5
ALG5 dolichyl-phosphate beta-glucosyltransferase
alpha mannosidase IIx
mannosidase alpha class 2A member 2
total:1
p125 is localized in endoplasmic reticulum exit sites and involved in their organization. 2005 to the paper
Chemicon International polyclonal anti-mannosidase II antibody was used in immunocytochemistry to study the localiation and function of p125 in endoplasmic reticulum.
ARSI
arylsulfatase family member I
B3GALT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
total:1
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
Invitrogen anti-Core1 antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA.
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
B3GNT6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
B3GNTL1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1
total:1
Sds22, a PP1 phosphatase regulatory subunit, regulates epithelial cell polarity and shape [Sds22 in epithelial morphology]. 2009 to the paper
Cappel rabbit anti-betaGal antibody (1:100) was used in immunocytochemistry in order to investigate the role of Sds22 in the regulation of epithelial cell polarity and shape.
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CA125
mucin 16, cell surface associated
total:6
Identification and characterization of ovarian cancer-initiating cells from primary human tumors. 2008 to the paper
Santa Cruz Biotechnology monoclonal anti-cancer antigen-125 (CA-125) antibody was used in immunocytochemistry to identify and characterize a self-renewing subpopulation of human ovarian tumor cells. more
calnexin
total:75
A Bacteriophage tailspike domain promotes self-cleavage of a human membrane-bound transcription factor, the myelin regulatory factor MYRF. 2013 to the paper
Santa Cruz Biotechnology rabbit anti-calnexin and goat anti-calnexin antibodies were used to perform western blot and immunocytochemistry in order to investigate the mechanism of self-cleavage of MYRF. more
calreticulin
total:39
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Stressgen anti-calreticulin antibody was used in western blot and immunocytochemistry to study the formation requirement of efficient hepatitis C virus particle. more
CMAS
cytidine monophosphate N-acetylneuraminic acid synthetase
CTSA
cathepsin A
total:3
Expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. 2007 to the paper
Rockland anti-human PPCA antibody was used in western blot to study the expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. more
DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
DPAGT1
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
DPM1
dolichyl-phosphate mannosyltransferase subunit 1, catalytic
total:1
Selectively oncolytic mutant of HSV-1 lyses HeLa cells mediated by Ras/RTN3. 2007 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-Dpm1 antibody was used in western blot to study mechanism mtHSV was targeted for treating tumors but not other organs.
DPM2
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
DPM3
dolichyl-phosphate mannosyltransferase subunit 3, regulatory
DSCR5
phosphatidylinositol glycan anchor biosynthesis class P
EDEM
ER degradation enhancing alpha-mannosidase like protein 1
EDEM2
ER degradation enhancing alpha-mannosidase like protein 2
EDEM3
ER degradation enhancing alpha-mannosidase like protein 3
EIF5A
eukaryotic translation initiation factor 5A
total:1
Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays. 2006 to the paper
Abcam eIF-5A antibody was used in immunohistochemistry to evaluate the potential of a large panel of tumor antigens as biomarkers for a serum-based screening test that can detect the presence of epithelial ovarian cancer.
ERp57
protein disulfide isomerase family A member 3
total:4
Endoplasmic reticulum chaperones stabilize nicotinic receptor subunits and regulate receptor assembly. 2007 to the paper
Stressgen anti-ERp57 Ab (1:2000 dilution) was used western blot to study the role of endoplasmic reticulum chaperones on nicotinic receptor subunits and assembly more
furin
furin, paired basic amino acid cleaving enzyme
total:7
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. 2009 to the paper
Thermo Fisher Scientific anti-furin antibody was used in immunocytochemistry in order to investigate the mechanism of the autonomous cholesterol regulation activated by adenovirus membrane protein RID-alpha. more
GALNT1
polypeptide N-acetylgalactosaminyltransferase 1
GALNT11
polypeptide N-acetylgalactosaminyltransferase 11
GALNT14
polypeptide N-acetylgalactosaminyltransferase 14
GALNT15
polypeptide N-acetylgalactosaminyltransferase 15
GALNT16
polypeptide N-acetylgalactosaminyltransferase 16
GALNT18
polypeptide N-acetylgalactosaminyltransferase 18
GALNT2
polypeptide N-acetylgalactosaminyltransferase 2
GALNT3
polypeptide N-acetylgalactosaminyltransferase 3
GALNT4
polypeptide N-acetylgalactosaminyltransferase 4
GALNT5
polypeptide N-acetylgalactosaminyltransferase 5
GALNT7
polypeptide N-acetylgalactosaminyltransferase 7
GALNT8
polypeptide N-acetylgalactosaminyltransferase 8
GALNTL5
polypeptide N-acetylgalactosaminyltransferase like 5
GALNTL6
polypeptide N-acetylgalactosaminyltransferase like 6
GCNT1
glucosaminyl (N-acetyl) transferase 1
total:1
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
Invitrogen anti-Core2 antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA.
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
GCNT4
glucosaminyl (N-acetyl) transferase 4
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
GFAT2
glutamine-fructose-6-phosphate transaminase 2
GFPT1
glutamine--fructose-6-phosphate transaminase 1
GLB1
galactosidase beta 1
total:7
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. 2010 to the paper
Invitrogene anti-beta-Galactosidase antibody was used in immunocytochemistry for immunofluorescent staining to investigate the role of the NMDA receptors in the regulation of nicotine-conditioned place preference in dopamine neurons. more
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GON 1
ADAM metallopeptidase with thrombospondin type 1 motif 20
GPAA1
glycosylphosphatidylinositol anchor attachment 1
GPI1
phosphatidylinositol glycan anchor biosynthesis class Q
GPI7
phosphatidylinositol glycan anchor biosynthesis class G
LMAN1
lectin, mannose binding 1
total:4
Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. 2010 to the paper
Sigma rabbit polyclonal anti-ERGIC-53 antibody (1:1000) was used in western blot in order to study the regulation of autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. more
mannosidase II
mannosidase alpha class 2A member 1
total:4
Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker. 2005 to the paper
Chemicon Int. anti-mannosidase II antibody was used in immunocytochemistry to study the tumor-specificity of both (22-1-1 and EBAG9) and the role in induction of apoptosis in human tumor cells. more
MCD4
phosphatidylinositol glycan anchor biosynthesis class N
MCFD2
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
MGAT2
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
MGAT4A
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
MGAT4B
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
MUC1
mucin 1, cell surface associated
total:28
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Lab Vision anti-MUC1-C antibody was used to perform immunoprecipitation in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers. more
MUC12
mucin 12, cell surface associated
MUC15
mucin 15, cell surface associated
MUC19
mucin 19, oligomeric
MUC2
mucin 2, oligomeric mucus/gel-forming
total:8
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. 2006 to the paper
Santa cruz biotechnology anti-Muc2 antibody was used to perform mmunohistochemistry assays in order to investigate the molecular regulation mechanisms of Smad4 in the process of normal pancreas development and pancreatic ductal adenocarcinomas (PDAC) growth. more
MUC3A
mucin 3A, cell surface associated
MUC3B
mucin 3B, cell surface associated
MUC4
mucin 4, cell surface associated
total:5
The clinicopathological and prognostic significance of MUC-1 expression in Japanese gastric carcinomas: an immunohistochemical study of tissue microarrays. 2008 to the paper
NovoCastra anti-human MUC-4 antibody was used to perform immunohistochemistry in order to study the clinicopathological significance of MUC-1 expression in gastric carcinomas. more
MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
total:10
TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells. 2013 to the paper
Neomarkers anti-MUC5AC antibody was used to perform western blot and immunocytochemistry in order to investigate the regulatory effect of TRPM5 activation on MUC5AC secretion from human colon goblet cells. more
MUC6
mucin 6, oligomeric mucus/gel-forming
total:4
Mixed-type gastric carcinomas exhibit more aggressive features and indicate the histogenesis of carcinomas. 2008 to the paper
Novocastra mouse anti-MUC-6 antibody was used in immunohistochemistry to investigate the pathobiological behaviors of gastric mixed-type (MT) carcinomas and gastric carcinogenesis. more
N acetylglucosaminyltransferase V
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
total:1
N-acetylglucosaminyltransferase V and beta1-6 branching N-linked oligosaccharides are associated with good prognosis of patients with bladder cancer. 2006 to the paper
Monoclonal antibody against human GnT-V SKNTDFFIGKPTILRELTS (Chikara Ohyama, Department of Urology, Hirosaki University School of Medicine) was used in immunohistochemistry to examine the relationship between GnT-V expression and clinicopathologic features of the patients with bladder cancer.
NEU1
neuraminidase 1
total:1
Expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. 2007 to the paper
Rockland anti-human neuraminidase 1 antibody was used in western blot and immunoprecipitation to study the expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients.
PGAP1
post-GPI attachment to proteins inositol deacylase 1
PIGB
phosphatidylinositol glycan anchor biosynthesis class B
PIGC
phosphatidylinositol glycan anchor biosynthesis class C
PIGF
phosphatidylinositol glycan anchor biosynthesis class F
PIGH
phosphatidylinositol glycan anchor biosynthesis class H
PIGK
phosphatidylinositol glycan anchor biosynthesis class K
PIGL
phosphatidylinositol glycan anchor biosynthesis class L
PIGM
phosphatidylinositol glycan anchor biosynthesis class M
PIGO
phosphatidylinositol glycan anchor biosynthesis class O
PIGS
phosphatidylinositol glycan anchor biosynthesis class S
PIGT
phosphatidylinositol glycan anchor biosynthesis class T
PIGU
phosphatidylinositol glycan anchor biosynthesis class U
PIGV
phosphatidylinositol glycan anchor biosynthesis class V
PIGW
phosphatidylinositol glycan anchor biosynthesis class W
PIGX
phosphatidylinositol glycan anchor biosynthesis class X
PROZ
protein Z, vitamin K dependent plasma glycoprotein
total:1
Down-regulation of factor IXa in the factor Xase complex by protein Z-dependent protease inhibitor. 2005 to the paper
The Binding Site sheep anti-protein Z antibody was used in western blot to study down-regulation of factor IXa in the factor xase complex by protein Z-dependent protease inhibitor.
SAE1
SUMO1 activating enzyme subunit 1
total:2
Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone. 2006 to the paper
Abcam anti-SAE1(ab5645) antibody was used to perform western blot in order to study the process of cAMP signaling induced dynamic changes in the SUMO pathway determine the endometrial response to progesterone. more
SAR1B
secretion associated Ras related GTPase 1B
SBSPON
somatomedin B and thrombospondin type 1 domain containing
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component
SEC23A
Sec23 homolog A, COPII coat complex component
total:3
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents Sec23 antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
SEC24A
SEC24 homolog A, COPII coat complex component
SEC24B
SEC24 homolog B, COPII coat complex component
SEC24C
SEC24 homolog C, COPII coat complex component
SEC24D
SEC24 homolog D, COPII coat complex component
SEC31A
SEC31 homolog A, COPII coat complex component
SENP1
SUMO specific peptidase 1
total:3
Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts. 2007 to the paper
Abgent polyclonal anti-SENP1 antibody was used to perform western blot in order to study the regulation of Fas-induced apoptosis by SUMO-1 more
SENP2
SUMO specific peptidase 2
total:2
Nitric oxide destabilizes Pias3 and regulates sumoylation. 2007 to the paper
Santa Cruz polyclonal anti-Senp2 was used to perform western blot in order to show that global sumoylation and Pias3 stabilization could be regulated by nitric oxide. more
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST6GAL2
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
ST6GALNAC1
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
ST6GALNAC2
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST6GALNAC3
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
ST6GALNAC4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
ST6GALNAC5
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
ST6GALNAC6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STS
steroid sulfatase
total:1
Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme. 2005 to the paper
Transkaryotic Therapies Inc. steroid sulfatase antiserum was used in western blot to study the expression, localization, structural, and functional characterization of the paralog of the Calpha-formylglycine-generating enzyme designated pFGE.
STT3A
STT3 oligosaccharyltransferase complex catalytic subunit A
STX
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
SUMF1
sulfatase modifying factor 1
total:1
Molecular characterization of the human Calpha-formylglycine-generating enzyme. 2005 to the paper
Qiagen rabbit polyclonal antibody against purified FGE-His was used in western blot and immunohistochemistry to study the functional and structural properties of human Calpha-formylglycine-generating enzyme (FGE)
SUMO-1
small ubiquitin like modifier 1
total:40
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Abcam anti-SUMO1 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
SUMO2
small ubiquitin like modifier 2
total:7
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Abcam anti-SUMO2/3 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
SUMO3
small ubiquitin like modifier 3
total:1
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein. 2006 to the paper
Zymed Laboratories anti-SUMO3 antibody was used in western blot to detect SUMO3 in HEK293 cells co-transfected with His-SUMO isoforms (SUMO1, SUMO2, and SUMO3) and full-length human tau or alpha-synuclein.
thrombospondin 1
total:20
Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. 2009 to the paper
Acbam mouse monoclonal antibody against human and mouse thrombospondin-1 was used in immunohistochemistry to investigate the role of transforming growth factor Beta signaling in the regulation of tumor growth. more
THSD1
thrombospondin type 1 domain containing 1
THSD4
thrombospondin type 1 domain containing 4
THSD7A
thrombospondin type 1 domain containing 7A
THSD7B
thrombospondin type 1 domain containing 7B
UAP1
UDP-N-acetylglucosamine pyrophosphorylase 1
UBA2
ubiquitin like modifier activating enzyme 2
total:2
Nitric oxide destabilizes Pias3 and regulates sumoylation. 2007 to the paper
BD Pharmingin monoclonal anti-Uba2 was used to perform western blot in order to show that global sumoylation and Pias3 stabilization could be regulated by nitric oxide. more
UBE2I
ubiquitin conjugating enzyme E2 I
total:10
The forkhead transcription factor Foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity. 2010 to the paper
Santa Cruz anti-UBC9 antibody was used in western blot in order to find the counterpart of forkhead transcription factor- FOXL2 and elucidate the role of its sumoylation more
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
UGGT2
UDP-glucose glycoprotein glucosyltransferase 2
uPAR
plasminogen activator, urokinase receptor
total:13
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 to the paper
Abcam rabbit anti-uPAR antibody was used to carry out immunofluorescence assays in order to investigate the association for increased expression of urokinase plasminogen activator and megakaryocyte differentiation in Quebec platelet disorder. more
VKORC1
vitamin K epoxide reductase complex subunit 1
GALNT17
polypeptide N-acetylgalactosaminyltransferase 17