Platelet homeostasis
gene
reagent
sample publication
sample review
apolipoprotein B
total:14
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Abcam anti-ApoB100 antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
ATP2A1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
total:4
Increased nitration of sarcoplasmic reticulum Ca2+-ATPase in human heart failure. 2005 to the paper
Affinity Bioreagents mouse monoclonal anti-SERCA2a antibody was used in western blot to study the role of SERCA2a nitration in heart failure in tissue from normal and failing human hearts. more
ATP2A3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
total:2
Regulation of the nitric oxide pathway genes by tetrahydrofurandiols: microarray analysis of MCF-7 human breast cancer cells. 2008 to the paper
Santa Cruz Biotechnologies ATP2A3 antibody was used in western blot in order to study the role of THF-diols in the regulation of the nitric oxide pathway genes more
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
total:5
Plasma membrane Ca2+-ATPase isoforms in frog crista ampullaris: identification of PMCA1 and PMCA2 specific splice variants. 2007 to the paper
Affinity BioReagents mouse monoclonal PMCA1 (1:200 1:600) antibody was used in immunohistochemistry to determine the identity and distribution of PMCA isoforms in frog crista ampullaris. more
ATP2B2
ATPase plasma membrane Ca2+ transporting 2
total:3
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Affinity BioReagents anti-PMCA2 antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
ATP2B3
ATPase plasma membrane Ca2+ transporting 3
total:2
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Affinity BioReagents anti-PMCA3 antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
ATP2B4
ATPase plasma membrane Ca2+ transporting 4
total:3
Topology of the yeast fatty acid transport protein Fat1p: mechanistic implications for functional domains on the cytosolic surface of the plasma membrane. 2007 to the paper
Dr. Guenther Daum mouse anti-Pma1p antibody was used in western blot to define the role of Fat1p in the transport of exogenous fatty acids. more
eNOS
nitric oxide synthase 3
total:36
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. 2009 to the paper
Upstate Laboratories anti-eNOS antibody was used for western blot in order to investigate the role of purinergic in the regulation of endothelial nitric oxide synthase activity in endothelial cells. more
GNAS
GNAS complex locus
total:4
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
United States Biological rabbit anti-GNAS antibody was used to carry out immunoprecipitation assays in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
GNB5
G protein subunit beta 5
total:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 to the paper
Dr. W. Simonds (NINDK) rabbit anti-VAChT antibody was used in western blot to study the localization and differential interaction of R7 RGS proteins with R7BP and R9AP in neurons of vertebrate retina.
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
total:1
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate. 2008 to the paper
Santa Cruz Biotechnology Inc anti-Gucy1a3 antibody was used for western blot in order to investigate the roles of elenium and isoflavones in the regulation of androgen-regulated gene expression in healthy rat dorsolateral prostate.
GUCY1B1
guanylate cyclase 1 soluble subunit beta 1
total:1
Characterization of a novel type of endogenous activator of soluble guanylyl cyclase. 2005 to the paper
Dr. David L. Garbers anti-1 subunit of sGC antibody was used in western blot and immunohistochemistry to identify a novel type of endogenous activator of soluble guanylyl cyclase.
iNOS
nitric oxide synthase 2
total:38
Hepatitis C virus targets over-expression of arginase I in hepatocarcinogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-iNOS antibody was used in western blot to study the role for elevated arginase expression in HCV associated HCC more
IRAG
murine retrovirus integration site 1 homolog
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
total:5
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 to the paper
Calbiochem IP3R1 antibody was used in western blot and immunohistochemistry to study the role of molecular alterations in the cerebellum of the PMCA2-null in Purkinje neurons. more
ITPR2
inositol 1,4,5-trisphosphate receptor type 2
total:2
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. 2005 to the paper
Santa Cruz Biotechnology goat anti-IP3R2 antibody was used in western blot to study the binding of phospholipid scramblase 1 to the promoter region of the inositol 1, 4, 5-triphosphate receptor type 1 more
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
total:3
Mice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss. 2007 to the paper
Alomone large conductance voltage and bk channel alpha-subunit antibody (1:100) was used in immunohistochemistry to study the physiological function and the contribution of type II transmembrane serine protease to the auditory function. more
KCNMB1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
KCNMB2
potassium calcium-activated channel subfamily M regulatory beta subunit 2
KCNMB3
potassium calcium-activated channel subfamily M regulatory beta subunit 3
KCNMB4
potassium calcium-activated channel subfamily M regulatory beta subunit 4
nNOS
nitric oxide synthase 1
total:8
Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor activation in primary neuronal cultures. 2009 to the paper
Zymed Laboratories anti-nNOS antibody was used for western blot in order to investigate the role of Estradiol in the regulation of nitric oxide formation in primary neuronal cultures. more
p38
mitogen-activated protein kinase 14
total:189
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 to the paper
Biosource International anti-p38 antibody was used to perform western blot in order to study the effect of NFAT5 on hyperosmolar stressed human limbal epithelial cells. more
PDE10A
phosphodiesterase 10A
total:1
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. 2006 to the paper
Abcam PDE10A mouse monoclonal antibody was used in western blot andimmunohistochemistry to study Cellular and subcellular localization of PDE10A.
PDE11A
phosphodiesterase 11A
total:1
Expression of PDE11A in normal and malignant human tissues. 2005 to the paper
FabGennix anti-Cyclic nucleotide phosphodiesterase 11A antibody was used in immunohistochemistry and western blot to study the expression of PDE11A in normal and malignant human tissues.
PDE1B
phosphodiesterase 1B
total:2
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. 2006 to the paper
Chemicon PDE1B1 antibody was used in western blot to study Cellular and subcellular localization of PDE10A. more
PDE3B
phosphodiesterase 3B
total:1
Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells. 2005 to the paper
Santa Cruz Biotech anti-PDE3B antibody was used in western blot to study the suppression of cyclic GMP-specific phosphodiesterase 5 promoting apoptosis and inhibiting growth in HT29 cells.
PDE5A
phosphodiesterase 5A
total:3
Expression of the PDE5 enzyme on human retinal tissue: new aspects of PDE5 inhibitors ocular side effects. 2008 to the paper
Abcam PDE5 antibody was used in western blot and immunohistochemistry to test the effect of PDE5 inhibitors on ophthalmic artery (OA) blood flow velocity. more
PECAM 1
platelet and endothelial cell adhesion molecule 1
total:125
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 to the paper
Millipore anti-mouse CD31 antibody was used to perform immunohistochemistry in order to study the inhibition of antifungal drug thiabendazole to tumor growth in a mouse xenograft model. more
PLA2G4A
phospholipase A2 group IVA
total:8
Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport.. 2009 to the paper
Santa Cruz Biotechnology anit-cPLA2a antibody was used to perform western blot and immunocytochemistry to study the role of cPLA2a in the formation of intercisternal tubular continuities and transport through the Golgi complex. more
PP2AC
protein phosphatase 2 catalytic subunit alpha
total:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate monoclonal anti-PP2Ac antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha
total:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate polyclonal anti-PP2A-A antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
PPP2R1B
protein phosphatase 2 scaffold subunit Abeta
total:2
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. 2007 to the paper
Sigma-Aldrich polyclonal antibody to the PP2APR65 subunit was used to perform western blot in order to investigate the functions of salt-inducible kinase-1. more
PRKG1
protein kinase cGMP-dependent 1
total:7
Hsp90/Hsp70 chaperone machine regulation of the Saccharomyces MAL-activator as determined in vivo using noninducible and constitutive mutant alleles. 2008 to the paper
Molecular Probes anti-PGK antibody was used in western blot in order to study the roles of Hsp90, Hsp70, and Sti1 in the regulation of the Saccharomyces MAL-activator more
SERCA2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
total:10
Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2. 2007 to the paper
Affinity BioReagents mouse anti-SERCA-2a antibody was used in western blot (1:1,000) to study the role of polycystin-2 in regulating ryanodine receptor-dependent calcium signaling. more
SHP-1
protein tyrosine phosphatase non-receptor type 6
total:16
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Santa Cruz Biotechnology anti-SHP-1 polyclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
SHP-2
protein tyrosine phosphatase non-receptor type 11
total:34
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-Shp2 antibody was used to perform western blot in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
SLC8A1
solute carrier family 8 member A1
total:1
Cellular and molecular determinants of altered Ca2+ handling in the failing rabbit heart: primary defects in SR Ca2+ uptake and release mechanisms. 2007 to the paper
Affinity BioReagents monoclonal anti-NCX antibody was used in western blot in order to investigate the cellular and molecular basis of heart failure (HF) caused by aberrant Ca2+ handling.
SLC8A3
solute carrier family 8 member A3
total:1
Ontogeny of NHE8 in the rat proximal tubule. 2007 to the paper
Santa Cruz Biotechnology Na+/Ca2+ exchanger (NCX) antibody (1:200) was used in immunocytochemistry to study the developmental expression of NHE8 in rat proximal tubules.
STIM1
stromal interaction molecule 1
total:4
The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. 2010 to the paper
Abnova anti-STIM1 antibody was used to carry out western blot analysis in order to investigate the role for STIM1 in coordinating Voltage- and store-operated calcium channels to generate coherent calcium signals. more
TRPC3
transient receptor potential cation channel subfamily C member 3
total:6
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC3 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
TRPC6
transient receptor potential cation channel subfamily C member 6
total:7
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC6 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
TRPC7
transient receptor potential cation channel subfamily C member 7
total:1
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells. 2005 to the paper
Santa Cruz anti-TRPC7 antibody was used in western blot to study the role of endogenous TRPC6 channels in Ca2+ signal generation.