Phase 1 - Functionalization of compounds
gene
reagent
sample publication
sample review
total:2
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Epitomics anti-Aldh1 antibody (1:150) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:4
GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome. 2008 to the paper
Santa Cruz Biotechnology goat anti-CYP19 (1:200) polyclonal antibody was used to perform immunohistochemistry in order to study the physiological functions of GPRC6A. more
total:15
Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer. 2009 to the paper
Chemicon International anti-CYP 1A1 antibody (AB1258) was used in western blot to determine the functional significance of aryl hydrocarbon receptor (AhR) in gastric carcinogenesis, and to explore the possible role of AhR in gastric cancer (GC) treatment more
total:2
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Alexis Biochemicals mouse anti-Mrp2 antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes. more
total:8
Preferential induction of cytochrome P450 1A1 over cytochrome P450 1B1 in human breast epithelial cells following exposure to quercetin. 2008 to the paper
Santa Cruz affinity purified goat polyclonal Cyp1B1 antibody was used in western blot in order to study the role of estrogen metabolism in estrogen-induced breast carcinogenesis more
total:1
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 to the paper
Santa Cruz anti-CYP24A1 (1:150) polyclonal antibody was used to perform immunocytochemistry in order to show that cathelicidin, a human antimicrobial peptide can be induced by vitamin D in the urinary bladder.
total:1
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 to the paper
Santa Cruz anti-CYP27B1 (D-20, 1:200) polyclonal antibody was used to perform immunocytochemistry in order to show that cathelicidin, a human antimicrobial peptide can be induced by vitamin D in the urinary bladder.
total:1
CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody. 2006 to the paper
BD Gentest anti-human CYP2A6 monoclonal antibody was used in western blotting and immunohistochemistry to study the role of CYP2A13 in human respiratory tissues and lung cancers.
total:3
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. 2009 to the paper
BD Biosciences-Pharmingen monoclonal anti-cytochrome c antibody was used in immunohistochemistry in order to introduce a rapid regulation of mitochondrial dynamics in acute kidney injury. more
total:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 to the paper
BD Gentest anti-CYP2C9 antibody (1:1000) was used in western blot in order to study the role of cardiomyocyte CPR and CPR-dependent enzymes in doxorubicin (Dox) mediated acute cardiotoxicity more
total:7
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 to the paper
Oxford Biomedical Research anti-CYP2E1 antibody (1:1000) was used in western blot in order to study the role of cardiomyocyte CPR and CPR-dependent enzymes in doxorubicin (Dox) mediated acute cardiotoxicity more
total:1
Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil. 2005 to the paper
Dr. Stephen Leeder (Mercy Children's Hospital) CYP3A5-specific polyclonal antibody was used in western blot to study the inhibition of CYP3A4 and CYP3A5 by verapamil
total:1
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 to the paper
Proteintech polyclonal anti-CYP4F11 antibody was used to perform western blot in order to clarify that retinoic acid could inhibit CYP4F11 expression in human keratinocyte-derived HaCaT cells by multiple signaling pathways including RXR and JNK pathways.
total:4
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. 2005 to the paper
Oxford Biomedical Research mouse monoclonal PGIS antibody was used in western blot to demonstrate that the mPGES-1 enzyme is a primary release mechanism of PGH2 accumulation. more
total:12
Cyclooxygenase-2 is involved in the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma induced by tumor necrosis factor-alpha. 2009 to the paper
Santa Cruz anti-COX-1 antibody was used to perform western blot and immunohistochemistry in order to show that the cyclooxygenase-2 can leads to the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma. more
total:3
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. 2009 to the paper
Abcam anti-TBXAS1 antibody was used to perform western blot in order to study the novel BRAF fusion gene in 7q34 duplication of pediatric low-grade astrocytomas detected by high density SNP-based genotype array analysis. more