PRC2 methylates histones and DNA
gene
reagent
sample publication
sample review
H2BS1
H2B.S histone 1
Dnmt1
DNA methyltransferase 1
total:12
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-DNMT1 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
Dnmt3a
DNA methyltransferase 3 alpha
total:5
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Epigentek anti-DNMT3a antibody was used for ChIP assays in order to study the role of SPARC in therapeutic process for ovarian cancer. more
DNMT3b
DNA methyltransferase 3 beta
total:5
Aberrant promoter methylation of SPARC in ovarian cancer. 2009 to the paper
Epigentek anti-DNMT3b antibody was used for ChIP assays in order to study the role of SPARC in therapeutic process for ovarian cancer. more
EED
embryonic ectoderm development
total:3
The polycomb repressive complex 2 is a potential target of SUMO modifications. 2008 to the paper
Upstate mouse anti-EED AA19 was used to perform western blot in order to show that the polycomb repressive complex 2 could be sumoylated post-translationally. more
Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
total:11
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. 2009 to the paper
Abcam anti-EZH2 was used to perform western blot in order to show the effects of G9a/KMT1C and jumonji-C type histone demethylases in histone H1 isotype 4 methylation and demethylation. more
H2AZ1
H2A.Z variant histone 1
total:1
Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin. 2007 to the paper
Dr. Peter Cheung (Ontario Cancer Institute) rabbit H2A.Z-specific antibodies (the H2A.Z-L1 antibody was raised against the peptide sequence KSSRTTSHGR, and the H2A.Z-C antibody was raised against the peptide sequence IPHIHKSLIGKKGQQKTV) was used in western blot and immunocytochemistry to study H2A.Z monoubiquitylation as the marker for its association with euchromatin or facultative heterochromatin
H2AX
H2A.X variant histone
total:62
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 to the paper
Millipore Gamma-H2AX antibody was used to perform western blot assay in order to study the requirement of RSFI in DSB repair. more
H3
H3 clustered histone 14
total:32
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 to the paper
Upstate anti-H3K4 antibody was used to perform RNA immunoprecipitation in order to analyze histone methylation at transcription start sites in human-specific prefrontal neurons of brain. more
H3-3B
H3.3 histone B
total:5
Hsp90alpha recruited by Sp1 is important for transcription of 12(S)-lipoxygenase in A431 cells. 2005 to the paper
Upstate Biotechnology acetyl-H3 antibody was used in ChIP assay to study 12 (S) Lipoxygenase transcription in A431 cells more
H4
H4 clustered histone 14
total:11
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Active Motif anti-H4K12Ac antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
H2BC1
H2B clustered histone 1
total:1
Testis/sperm-specific histone 2B in the sperm of donors and subfertile patients: variability and relation to chromatin packaging. 2007 to the paper
Chemicon International TSH2B antibody was used in western blot to assesse the association of TSH2B with chromatin compaction status.
H2BC5
H2B clustered histone 5
total:1
p53 chromatin epigenetic domain organization and p53 transcription. 2009 to the paper
Abcam anti-histone H2Bantibody was used to perform immunoprecipitation in order to demonstrate that physical barrier due to the folding of chromatin in domain II can give rise to the depletion of RNA polymerase II.
H3C6
H3 clustered histone 6
total:5
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Abcam anti-Histone 3, anti-H3 K9Me, and anti-H3 S10ph antibodies were used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
H2AC20
H2A clustered histone 20
total:6
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 to the paper
Abcam anti-H2A antibody 1:1,000 was used for western blot in order to investigate the roles of H3K9Ac and H3K56Ac in the regulation of DNA-damage-responsive in human cells more
H2BC21
H2B clustered histone 21
total:10
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-H2B antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
JARID2
jumonji and AT-rich interaction domain containing 2
MTF2
metal response element binding transcription factor 2
RbAP46
RB binding protein 7, chromatin remodeling factor
total:6
CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene. 2006 to the paper
Abcam RbAp46 antibody was used in immunoprecipitation to study the molecular mechanism (s) by which CTIP2 contributes to T cell development and axonal. more
RbAp48
RB binding protein 4, chromatin remodeling factor
total:8
The polycomb repressive complex 2 is a potential target of SUMO modifications. 2008 to the paper
Upstate rabbit anti-RbAp48 13D10 was used to perform western blot in order to show that the polycomb repressive complex 2 could be sumoylated post-translationally. more
Suz12
SUZ12 polycomb repressive complex 2 subunit
total:9
Long noncoding RNA as modular scaffold of histone modification complexes. 2010 to the paper
Abcam rabbit anti-SUZ12 antibody was used to carry out ChIP assays in order to investigate the role for long intergenic noncoding RNAs as scaffolds to regulate histone modification complexes and gene expression. more