PPARA activates gene expression
gene
reagent
sample publication
sample review
ABCA1
ATP binding cassette subfamily A member 1
total:10
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Abcam mouse monoclonal anti-ABCA1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
ABCB4
ATP binding cassette subfamily B member 4
total:1
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Signet Laboratories mouse anti-MDR antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes.
ACSL1
acyl-CoA synthetase long chain family member 1
AGT
angiotensinogen
total:6
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 to the paper
IgG corporation rabbit polyclonal anti-ang II serum was used in immunohistochemistry in order to study the glomerular AGT's expression and its correlation with expression of other RAS components more
ANGPTL4
angiopoietin like 4
total:1
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. 2005 to the paper
Karen S. L. Lam (University of Hong Kong, China) monoclonal ANGPTL4 antibody was used in ELISA to study its effect in mice
apoA-I
apolipoprotein A1
total:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 to the paper
Abcam polyclonal rabbit anti-apoA-I antibody (1:10,000) was used for western blot in order to investigate the distinct roles of apolipoprotein components in a transgenic mouse model. more
CD36
CD36 molecule
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
connective tissue growth factor
cellular communication network factor 2
total:11
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Santa Cruz Biotechnologies CTGF antibody (1:2,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
CPT2
carnitine palmitoyltransferase 2
total:1
Coimmunoprecipitation of FAT/CD36 and CPT I in skeletal muscle increases proportionally with fat oxidation after endurance exercise training. 2006 to the paper
Santa Cruz Biotechnology polyclonal antibody against CPT I was used in immunoprecipitation to isolate CPT I from human skeletal muscle.
Cyp1A1
cytochrome P450 family 1 subfamily A member 1
total:15
Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer. 2009 to the paper
Chemicon International anti-CYP 1A1 antibody (AB1258) was used in western blot to determine the functional significance of aryl hydrocarbon receptor (AhR) in gastric carcinogenesis, and to explore the possible role of AhR in gastric cancer (GC) treatment more
FABP1
fatty acid binding protein 1
total:1
Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. 2010 to the paper
R&D Systems goat anti-human L-FABP polyclonal antibody was used to perform western blot in order to study the prognostic ability of urinary liver-type fatty acid-binding protein (L-FABP) in Acute kidney injury (AKI).
FHL2
four and a half LIM domains 2
total:4
Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway. 2009 to the paper
Santa Cruz Biotechnology anti-FHL2 antibody was used for western blot to study the suppressing role of human FHL1 family members in the modulation of tumor cell growth through a TGF-beta like signaling pathway. more
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
total:1
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-HMGCR antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism.
NF-YA
nuclear transcription factor Y subunit alpha
total:13
Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-NF-YA antibody was used in immunoblot in order to study the role of tuberin and OGG1 in the pathogenesis of angiomyolipoma in TSC patients. more
NPAS2
neuronal PAS domain protein 2
total:1
The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response. 2008 to the paper
Santa Cruz rabbit polyclonal anti-NPAS2 antibody was used to perform western blot in order to show that circadian gene NPAS2 is a putative tumor suppressor involved in DNA damage response.
NRF1
nuclear respiratory factor 1
total:1
Endurance exercise as a countermeasure for aging. 2008 to the paper
SantaCruz anti-NRF-1 antibody was used in western blot in order to investigate whether the mitochondrial dysfunction and reduced insulin sensitivity are inevitably caused by aging.
PLIN2
perilipin 2
total:2
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Santa Cruz anti-ADRP antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
PPAR
peroxisome proliferator activated receptor alpha
total:9
Integration of microRNA miR-122 in hepatic circadian gene expression. 2009 to the paper
Abcam rabbit polyclonal antibody PPAR was used for immunoprecipitation in order to study the circadian gene expression of integration of microRNA miR-122 in hepatic. more
RGL
ral guanine nucleotide dissociation stimulator like 1
Sp1
Sp1 transcription factor
total:70
Sp1 and KLF15 regulate basal transcription of the human LRP5 gene. 2010 to the paper
Santa Cruz anti-Sp1 antibody was used to perform ChIP assay in order to study the regulatory function of Sp1 and KLF15 on basal transcription of the human LRP5 gene. more
SREBF2
sterol regulatory element binding transcription factor 2
total:3
Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. 2005 to the paper
Santa Cruz Biotechnology anti-SREBP2 antibody was used in western blot to study the effect of liver X receptor alpha on SREBP1c-mediated Abcd2 expression more
SREBP-1
sterol regulatory element binding transcription factor 1
total:11
Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. 2009 to the paper
NeoMarkers monoclonal SREBP-1 antibody was used in western blot in order to study the mechanism by which the activation of Wnt/beta-catenin signaling in skeletal muscle cells can improve insulin sensitivity. more
SULT2A1
sulfotransferase family 2A member 1
total:2
Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver. 2006 to the paper
Pan-Vera polyclonal rabbit anti-human SULT2A1 antibody was used in western blot to study the different expression pattern of hepatic SULT1A1, SULT1E1, and SULT2A1. more
TRB3
tribbles pseudokinase 3
total:2
Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis. 2008 to the paper
EMD Chemicals anti-TRB3 antibody was used to perform western blot in order to study the response of the mTORC1 signaling after the inhibition of protein synthesis. more
TXNRD1
thioredoxin reductase 1
total:2
Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities. 2009 to the paper
Santa Cruz Biotechnology anti-TrxR1 antibody was used in western blot in order to show that adiponectin haploinsufficiency can promote mammary tumorigenesis through inhibition of PTEN activity and activation of PI3K/Akt signalling pathway. more