PERK regulates gene expression
gene
reagent
sample publication
sample review
ATF3
activating transcription factor 3
total:7
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. 2008 to the paper
Calbiochem anti-ATF3(c-19) antibody was used to perform western blot in order to study the important role of CD30 signaling in Hodgkin's and anaplastic large cell lymphoma (ALCL) cell lines. more
ATF4
activating transcription factor 4
total:11
Pharmacological brake-release of mRNA translation enhances cognitive memory. 2013 to the paper
Santa Cruz Biotechnologies anti-CREB-2 antibody was used to perform western blot in order to investigate the molecular mechanism of memory consolidation. more
Bip
heat shock protein family A (Hsp70) member 5
total:47
RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. 2013 to the paper
Abcam GRP78/BiP rabbit polyclonal (1:25) was used to perform the immunoblotting to study the translation of a subset of mRNAs encoding secretory proteins potentiated by RanBP2/Nup358. more
DDIT3
DNA damage inducible transcript 3
total:17
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
ABR Affinity BioReagents anti-CHOP was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
eIF2alpha
eukaryotic translation initiation factor 2 subunit alpha
total:43
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
Abcam anti-eIF2alpha was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
HERPUD1
homocysteine inducible ER protein with ubiquitin like domain 1
total:2
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Abgent anti-Herp antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
IL-8
C-X-C motif chemokine ligand 8
total:46
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
R&D systems anti-IL8 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
MCP-1
C-C motif chemokine ligand 2
total:14
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
Santa Cruz anti-MCP-1 antibody was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
PERK
eukaryotic translation initiation factor 2 alpha kinase 3
total:14
The role of nitric-oxide synthase in the regulation of UVB light-induced phosphorylation of the alpha subunit of eukaryotic initiation factor 2. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-PERK antibody was used in immunoprecipitation in order to demonstrate that UVB-induced eIF2 phosphorylation is regulated by NOS. more