PD-1 signaling
gene
reagent
sample publication
sample review
CD247
CD247 molecule
total:68
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD3 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
CD274
CD274 molecule
total:4
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. 2009 to the paper
Biolegend anti-B7-H1 antibody was used in flow cytometry to harvest and stain infected cells in order to investigate the role of the JAK-STAT1 pathway in the regulation of the replication of HSV-1. more
CD3
CD3d molecule
total:43
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
eBioscience anti-CD3 antibody was used to perform cell culture in order to study how gut microbiota regulate immunesystem. more
CD3E
CD3e molecule
total:20
Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1. 2012 to the paper
eBioscience anti-CD3 monoclonal antibody OKT3 was used to stimulate CD4+ T cell in order to study novel HIV-1 capture mechanism. more
CD3G
CD3g molecule
total:48
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD3 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
CD4
CD4 molecule
total:118
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Beckman coulter anti-CD4 PC5 was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
CSK
C-terminal Src kinase
total:7
Leukocyte-associated Ig-like receptor-1 has SH2 domain-containing phosphatase-independent function and recruits C-terminal Src kinase. 2006 to the paper
Santa Cruz anti-Csk antibody was used in immnoprecipitation to study the role of leukocyte-associated Ig-like receptor-1. more
DPB1
major histocompatibility complex, class II, DP beta 1
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
total:1
Expression of CD80 and CD86 costimulatory molecules are potential markers for better survival in nasopharyngeal carcinoma. 2007 to the paper
Novocastra Laboratories anti-HLA Class II (DR) was used to perform immunohistochemistry in order to show CD80 and CD86 may be potential nasopharyngeal carcinoma markers for clinical outcome.
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
total:1
Spontaneous lupus-like syndrome in HLA-DQ2 transgenic mice with a mixed genetic background. 2010 to the paper
Becton Dickinson anti-DQ (TU39) antibody was used to perform flow cytometry in order to investigate the role of HLA-DQ2 in the pathogenesis of associated immune disorders.
HLA-DR
major histocompatibility complex, class II, DR alpha
total:22
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 to the paper
Beckman-Coulter anti-HLA DR- PC5 was used to perform flow cytometry in order to show that IRAK-1 blockade is important for tolerance of human DCs induced by TLR2 and TLR4 stimulation. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB3
major histocompatibility complex, class II, DR beta 3
HLA-DRB4
major histocompatibility complex, class II, DR beta 4
HLA-DRB4
major histocompatibility complex, class II, DR beta 4
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
total:2
Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. 2008 to the paper
BD Pharmingen fluorochrome-conjugated HLA-DR antibody was used in flow cytometry in order to determine whether high LPS levels are associated with increased monocyte activation and HAD more
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
total:2
Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. 2008 to the paper
BD Pharmingen fluorochrome-conjugated HLA-DR antibody was used in flow cytometry in order to determine whether high LPS levels are associated with increased monocyte activation and HAD more
Lck
LCK proto-oncogene, Src family tyrosine kinase
total:18
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Upstate Biotechnology Lck antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts. more
PDCD1
programmed cell death 1
total:1
FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. 2008 to the paper
Ebioscience anti-PD-1 antibody (J116 clone) was used in immunohistochemistry to study the role for FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes in theraping high-risk breast cancer patients paraffin section from human tumor.
PDCD1LG2
programmed cell death 1 ligand 2
total:3
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. 2009 to the paper
Biolegend B7-DC antibody was used in flow cytometry to harvest and stain infected cells in order to investigate the role of the JAK-STAT1 pathway in the regulation of the replication of HSV-1. more
SHP-1
protein tyrosine phosphatase non-receptor type 6
total:16
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Santa Cruz Biotechnology anti-SHP-1 polyclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
SHP-2
protein tyrosine phosphatase non-receptor type 11
total:34
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-Shp2 antibody was used to perform western blot in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
TRB
T cell receptor beta locus
total:7
Potential roles of a special CD8 alpha alpha+ cell population and CC chemokine thymus-expressed chemokine in ovulation related inflammation. 2009 to the paper
BD Bio Sciences TcR antibody was used in flow cytometry in order to study the effect of ovarian CD8alphaalpha+ cells and CC chemokine TECK on the ovulation-related inflammation. more