Nucleotide-binding domain and leucine rich repeat containing family
gene
reagent
sample publication
sample review
CIITA
class II major histocompatibility complex transactivator
total:5
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. 2009 to the paper
Biolegend anti-MHC class II-APC antibody was used in flow cytometry to harvest and stain infected cells in order to investigate the role of the JAK-STAT1 pathway in the regulation of the replication of HSV-1. more
NAIP
NLR family apoptosis inhibitory protein
total:1
Estrogen suppresses uterine epithelial apoptosis by inducing birc1 expression. 2008 to the paper
Chemicon polyclonal anti-NAIP (1:100) antibody was used in immunocytochemistry to study the role of birc1 in suppressing apoptosis in the uterus.
CLR16 2
NLR family CARD domain containing 3
NLRP2
NLR family pyrin domain containing 2
total:4
Toll-like receptor 2 and NALP2 mediate induction of human beta-defensins by fusobacterium nucleatum in gingival epithelial cells. 2009 to the paper
Abcam anti-human NALP2 polyclonal antibody was used to perform western blot in order to study TLR2 and NALP2 mediated induction of HBDs by F. nucleatum in gingival epithelial cells. more
NLRP3
NLR family pyrin domain containing 3
total:1
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. 2006 to the paper
Alexis rabbit polyclonal anti-Nalp3 antibody (which recognizes WT, R260W, and D303N cryopyrins) was used in human cells and in immunocytochemistry to study the role of cryopyrin and pyrin in activating caspase-1.
NOD1
nucleotide binding oligomerization domain containing 1
NOD2
nucleotide binding oligomerization domain containing 2
total:2
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. 2006 to the paper
Cayman Chemical NOD2-specific rabbit antiserum was used in immunoprecipitation and western blot to measure its expression in primary keratinocytes and transfected HEK293 cells. more