Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
gene
reagent
sample publication
sample review
EIF4A3
eukaryotic translation initiation factor 4A3
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
ProteinTech eIF4A3 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
EIF4G1
eukaryotic translation initiation factor 4 gamma 1
total:5
Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. 2010 to the paper
Santa Cruz Biotechnology anti-EIF4G antibody was used to perform immunocytochemistry in order to study the interaction between TDP-43 and proteins that regulate RNA metabolism. more
ETF1
eukaryotic translation termination factor 1
FAU
FAU ubiquitin like and ribosomal protein S30 fusion
MAGOH
mago homolog, exon junction complex subunit
total:3
The exon junction complex component Magoh controls brain size by regulating neural stem cell division. 2010 to the paper
Proteintech anti-Magoh antibody was used to perform immunohistochemical assays in order to study the genetic mechanisms of Magoh in controlling brain size. more
NCBP1
nuclear cap binding protein subunit 1
total:2
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Protein-Tech anti-CBP80 antibody was used in western blot in order to investigate the function of surveillance complex associated with ribosome during nonsense-mediated mRNA decay (NMD). more
NCBP2
nuclear cap binding protein subunit 2
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Abgent CBP20 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
PABPC1
poly(A) binding protein cytoplasmic 1
total:7
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal anti-PABP antibody(10E10, 1:200) was used to perform immunofluorescence in order to characterize the TAR DNA-binding Protein-43's alternative isoforms inclusion body. more
PP2AC
protein phosphatase 2 catalytic subunit alpha
total:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate monoclonal anti-PP2Ac antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha
total:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate polyclonal anti-PP2A-A antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
PPP2R2A
protein phosphatase 2 regulatory subunit Balpha
total:2
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate monoclonal anti-PP2A-B antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
RBM8A
RNA binding motif protein 8A
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Sigma Y14 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
ribosomal protein L15
total:1
Overexpression of ribosomal protein L15 is associated with cell proliferation in gastric cancer. 2006 to the paper
Neomarker anti-RPL15 antibody was used in western blot and immunohistochemistry to study the relation between overexpression of ribosomal protein L15 and cell proliferation in gastric cancer.
ribosomal protein L26
total:1
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. 2008 to the paper
Bethyl Laboratories rabbit anti-Rpl26 antibody was used for western blot in order to investigate the role of nucleolar protein B23 in the regulation of the vertebrate SUMO pathway.
ribosomal protein L37a
total:1
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. 2008 to the paper
Abnova rabbit anti-RPL37A antibody was used for western blot in order to investigate the role of nucleolar protein B23 in the regulation of the vertebrate SUMO pathway.
ribosomal protein S3
total:3
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Cell Signaling Technology rpS3 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay. more
RNPS1
RNA binding protein with serine rich domain 1
RPL11
ribosomal protein L11
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Invitrogen rpL11 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
RPL7
ribosomal protein L7
total:2
RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits. 2010 to the paper
Abcam goat anti-human RPL7 antibody was used to perform western blot in order to study the role of RRP1B and PP1 in mammalian cell nucleoli and pre-60S ribosomal subunits. more
RPL7A
ribosomal protein L7a
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Cell Signaling Technology rpL7a antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
RPLP0
ribosomal protein lateral stalk subunit P0
total:1
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. 2008 to the paper
Proteintech Group rabbit anti-RplP0 antibody was used for western blot in order to investigate the role of nucleolar protein B23 in the regulation of the vertebrate SUMO pathway.
RPLP1
ribosomal protein lateral stalk subunit P1
RPLP2
ribosomal protein lateral stalk subunit P2
RPS16
ribosomal protein S16
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Abcam rpS16 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
RPS27
ribosomal protein S27
total:3
Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylation. 2009 to the paper
Millipore anti-Mps1 antibody was used to perform immunohistochemistry in order to study the regulation of Mps1 phosphorylation in kinetochore targeting and spindle checkpoint signaling. more
RPS27A
ribosomal protein S27a
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
RPS6
ribosomal protein S6
total:36
p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. 2012 to the paper
Cell Signalling anti-S6 (rabbit monoclonal) antibody was used to perform immunoblotting in order to study the effect of p180 on the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. more
RPSA
ribosomal protein SA
total:2
67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells. 2005 to the paper
Abcam polyclonal 67LR antibody (Ab711) was used in western blot and immunoprecipitation to study the role of 67-kDa Laminin Receptor Escherichia coli K1 internalization in human brain microvascular endothelial cells more
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
SMG5
SMG5 nonsense mediated mRNA decay factor
SMG6
SMG6 nonsense mediated mRNA decay factor
SMG7
SMG7 nonsense mediated mRNA decay factor
SMG8
SMG8 nonsense mediated mRNA decay factor
SMG9
SMG9 nonsense mediated mRNA decay factor
UPF1
UPF1 RNA helicase and ATPase
total:2
Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X. 2009 to the paper
San Diego polyclonal anti-human Upf-1 (hUpf-1) antibody was used in western blot in order to study that GABAA receptor alpha1 subunit mutation, 975delC, S326fs328X induce the activation of NMD and ERAD which contribute to epileptogenesis. more
UPF2
UPF2 regulator of nonsense mediated mRNA decay
UPF3A
UPF3A regulator of nonsense mediated mRNA decay
UPF3B
UPF3B regulator of nonsense mediated mRNA decay