Non-specific protein-tyrosine kinase
gene
reagent
sample publication
sample review
total:35
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Calbiochem c-Abl antibody (1:1,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
total:1
The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription. 2006 to the paper
Cell Signaling polyclonal anti-WSTF antibody (which recognizes C-terminal WSTF) was used in human HeLa cells and in immunoprecipitation and ChIP assay to study the interaction of WSTF-SNF2h chromatin remodeling complex with several nuclear proteins in transcription.
total:7
Leukocyte-associated Ig-like receptor-1 has SH2 domain-containing phosphatase-independent function and recruits C-terminal Src kinase. 2006 to the paper
Santa Cruz anti-Csk antibody was used in immnoprecipitation to study the role of leukocyte-associated Ig-like receptor-1. more
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:2
A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer. 2006 to the paper
Santa Cruz goat polyclonal antibodies generated against either Fes amino-terminal (Fes N-19) or carboxyl-terminal (Fes C-19) peptides were used in western blot to investigate Fes expression in human 293T cells, as well as HT-29 and HCT 116 cells, and in immunohistochemstry to detect Fes expression in normal adult human colon sections and human colorectal cancer cell line HT-29. more
total:1
Rak functions as a tumor suppressor by regulating PTEN protein stability and function. 2009 to the paper
Proteintech Group rabbit polyclonal anti-Rak antibody was used in western blot in order to demonstrate that Rak acts as a tumor suppressor gene through the mechanism of regulating PTEN protein stability and function.
total:19
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-FYN antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking. more
total:9
Regulation of p73 by Hck through kinase-dependent and independent mechanisms. 2007 to the paper
Santa Cruz rabbit polyclonal anti-Hck was used to perform western blot and immunoprecipitation and immunocytochemistry in order to show the mechanisms through which Hck regulates p73 function more
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
BD Biosciences anti-Btk/Itk (pY551/pY511) was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:22
Identification of human thioredoxin as a novel IFN-gamma-induced factor: mechanism of induction and its role in cytokine production. 2008 to the paper
Santa Cruz anti-Jak1 and anti-p-Jak1 were used to perform western blot in order to show that thioredoxin is an IFN-gamma-induced factor and plays a role for cytokine production. more
total:34
Covering a broad dynamic range: information processing at the erythropoietin receptor. 2010 to the paper
Upstate anti-JAK2 antibody was used to carry out immunoprecipitation assay and western blot analysis in order to determine the receptor property of erythropoietin receptor during receptor signaling activation. more
total:9
The JAK kinase inhibitor CP-690,550 suppresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation. 2008 to the paper
Upstate Biotechnology anti-JAK3(04-011) antibody was used to perform western blot in order to study the JAK kinase inhibitor reduces the growth of human polycythemia vera cells. more
total:18
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Upstate Biotechnology Lck antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts. more
total:20
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 to the paper
Santa Cruz anti-Lyn 44 antibody was used to perform western blot in order to study the roles of the lipid raft-dependent Fc secre tRI ubiquitination in the regulation of receptor endocytosis. more
total:35
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. 2009 to the paper
Santa Cruz Biotechnology anti-PKCdelta antibody was used in western blot to study the mechanism underlying PKCalpha suppressing tumor in the intestine. more
total:30
The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection.. 2009 to the paper
Epitomics rabbit monoclonal phospho-PKR antibody was used to perform western blot in order to investigate the relations between E1B-55K/E4orf6 and eIF2. more
total:3
Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression. 2005 to the paper
Santa Cruz Biotechnology anti-BRK polyclonal antibody was used in western blot to study that tyrosine phosphorylation of Sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression. more
total:27
Supervillin reorganizes the actin cytoskeleton and increases invadopodial efficiency. 2009 to the paper
BD Biosciences monoclonal mouse anti-phospho-focal adhesion kinase (FAK) antibody was used in immunocytochemistry to study the role of supervillin (SV) in the function of tumor cell actin-rich protrusions. more
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:12
Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk.. 2008 to the paper
Santa Cruz Biotech anti-Syk antibody was used to perform western blot in order to study the interaction between NS5A and Syk. more
total:13
Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. 2008 to the paper
Santa Cruz Biotechnology anti-Tyk2 and anti-p-Tyk2 polyclonal antibodies were used to perform immunoprecipitation and western blot assays in order to demonstrate that Z3 is a novel specific inhibitor that can suppresses Jak2-mediated pathologic cell growth. more
total:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-WEE1 antibody was used to carry out western blot analysis in order to investigate the mechanism of FANCM degradation during mitosis. more
total:6
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 to the paper
Upstate rabbit anti-Yes1 (06.514) polyclonal antibody was used to perform western blot and immunocytochemistry in order to investigate the molecular mechanisms underlying CRMP2 function in CXCL12-induced T lymphocyte migration. more
total:19
Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function. 2006 to the paper
Upstate ZAP-70 antibody was used in western blot to study the association of ILT2 and murine MHC class I molecules in vivo. more