Non-integrin membrane-ECM interactions
gene
reagent
sample publication
sample review
alpha-actinin
actinin alpha 1
total:13
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 to the paper
Santa Cruz anti-ACTN1 antibody was used for western blot in order to investigate the role of CaMKII in the regulation of pressure overload-induced cardiac hypertrophy to heart failure in mice. more
beta1 integrin
integrin subunit beta 1
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
CASK
calcium/calmodulin dependent serine protein kinase
total:6
SUMOylation of the MAGUK protein CASK regulates dendritic spinogenesis. 2008 to the paper
Santa Cruz rabbit polyclonal anti-CASK was used to perform western blot in order to show that dendritic spinogenesis is regulated by SUMOylation of the MAGUK protein CASK. more
DAG1
dystroglycan 1
total:5
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. 2010 to the paper
Hycult Biotech anti ADG antibody was used to perform immunohistochemistry in order to study the function of the astrocytic antigen aquaporin 4 (AQP-4) in inflammatory demyelinating diseases. more
DDR1
discoidin domain receptor tyrosine kinase 1
total:8
Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. 2009 to the paper
R&D Systems anti-NEP antibody was used in immunohistochemistry in order to investigate the role of neprilysin in the regulation of pulmonary vascular remodeling in response to chronic hypoxia. more
DDR2
discoidin domain receptor tyrosine kinase 2
total:1
Discoidin domain receptor 2 mediates tumor cell cycle arrest induced by fibrillar collagen. 2005 to the paper
Regeneron Pharmaceuticals polyclonal anti-DDR2 antibody (R2-JM) was used in western blot to study a novel direct mechanism by which cell contact with fibrillar collagen restricts proliferation.
dystrophin
total:8
Long-term survival of transplanted stem cells in immunocompetent mice with muscular dystrophy. 2008 to the paper
Novacastra anti-dystrophin mouse monoclonal antibody NCL-DYS2 was used in immunohistochemistry at 1:100 in order to study the role of duchenne muscular dystrophy in the long-term survival of transplanted stem Cells more
FGF-2
fibroblast growth factor 2
total:20
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. 2009 to the paper
Chemicon rabbit polyclonal anti-FGF2 antibody was used in western blot to study the role for endothelial-derived FGF2 in the progression of pulmonary hypertension in humans and rodents. more
integrin alpha v
integrin subunit alpha V
total:24
TGFBI expression is associated with a better response to chemotherapy in NSCLC. 2010 to the paper
Chemicon Interational anti-integrin alphavbeta3 monoclonal was used to perform flow cytometry in order to determine if this integrin influences TGFBI-mediated NSCLC cell susceptibility to chemotherapy. more
integrin alpha2
integrin subunit alpha 2
total:15
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha2 antibody (clone P1E6) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
integrin beta3
integrin subunit beta 3
total:28
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal integrin beta3 antibody (1:1000) was used in western blot in order to study the role of activated state of p42/44 and p38 in MMP-13 expression. more
ITGA6
integrin subunit alpha 6
total:20
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD49f-PE antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
ITGB4
integrin subunit beta 4
total:12
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-ITGB4 antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
ITGB5
integrin subunit beta 5
total:9
Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation. 2008 to the paper
Chemicon alphaVbeta5 mAb was used to perform immunoblotting in order to illustrate that transforming growth factor, beta-induced (beta ig-h3/TGFBI) could enhance the aggressiveness and alter the metastatic properties of colon cancer cells in vivo. more
LAMA2
laminin subunit alpha 2
total:4
Quiescent fibroblasts exhibit high metabolic activity. 2010 to the paper
Abnova mouse anti-LAMA2 polyclonal antibody was used to perform western blot in order to study the function of quiescent fibroblasts. more
LAMA3
laminin subunit alpha 3
total:3
Nephrotic syndrome and aberrant expression of laminin isoforms in glomerular basement membranes for an infant with Herlitz junctional epidermolysis bullosa. 2005 to the paper
Chemicon monoclonal anti-laminin alpha3 chain antibody P3H9 was used in immunohistochemistry to study the association of laminin isoforms with herlitz junctional epidermolysis bullosa in a case complicated by nephrotic syndrome. more
LAMA5
laminin subunit alpha 5
total:9
Analysis of human muscle stem cells reveals a differentiation-resistant progenitor cell population expressing Pax7 capable of self-renewal. 2009 to the paper
Santa Cruz goat anti-laminin 1 sc6016 was used to perform flow cytometry in order to study the role of Pax7 in human satellite stem cell differentiation and self renewal. more
LAMB2
laminin subunit beta 2
total:4
Overexpression of beta1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases. 2005 to the paper
Developmental Studies Hybridoma Bank mouse monoclonal anti-Laminin beta2 chain antibody was used in western blot and immunohistochemistry to study the overexpression of beta1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases. more
LAMC2
laminin subunit gamma 2
total:6
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
Millipore anti-laminin gamma 2 chain antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
laminin
laminin subunit beta 1
total:16
Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle. 2008 to the paper
Chemicon rabbit polyclonal laminin antibody was used in immunohistochemistry in order to study the role of talin 1 in the development and function of skeletal muscle more
PDGFA
platelet derived growth factor subunit A
total:5
Antiangiogenic characteristics of astrocytes from optic nerve heads with primary open-angle glaucoma. 2008 to the paper
Santa Cruz Biotechnology anti-PDGF-A polyclonal antibody was used to perform western blot in order to study the role of astrocytes on angiogenesis. more
PDGFB
platelet derived growth factor subunit B
total:5
Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-PDGF-B antibody was used in immunohistochemistry to study whether the expression of tyrosine kinase growth factor receptors is constant or varies between and within individual colon cancer neoplasms. more
perlecan
heparan sulfate proteoglycan 2
total:5
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. 2006 to the paper
Chemicon monoclonal anti-perlecan antibody (MAB 1948) was used in frozen sections from mouse and in immunohistochemistry to study the identification of WARP as a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. more
PKC alpha
protein kinase C alpha
total:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-PKCAalpha antibody was used in western blot in order to study the function of TMX3 in eye development. more
SDC2
syndecan 2
total:2
Syndecan-4 is required for thrombin-induced migration and proliferation in human vascular smooth muscle cells. 2005 to the paper
Seikagaku HSPG neo-epitope (exposed after heparitinase III digestion, clone 3G10) antibody was used in western blot to study thrombin-induced human vascular smooth muscle cell migration and proliferation more
SDC3
syndecan 3
total:1
Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue. 2006 to the paper
Zymed Laboratories rabbit anti syndecan-3 antibody was used in immunohistochemistry to study its expression in human uterine tissue during prolonged labour
SDC4
syndecan 4
total:3
Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans. 2008 to the paper
Santa Cruz Biotechnology anti-syndecan-4 antibody was used in immunocytochemistry to study the effect of heparanase on cell adhesion and spreading. more
syndecan
syndecan 1
total:26
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 to the paper
Cell Sciences B-A38 (Syndecan-1) antibody was used in western blot in order to demonstrate that heparanase can promote expression of syndecan-1 in the nucleus. more
TGF-beta1
transforming growth factor beta 1
total:35
Noncanonical TGF? signaling contributes to aortic aneurysm progression in Marfan syndrome mice. 2011 to the paper
R&D Systems anti-TGFbeta antibody was used for intraperitoneal injection in order to study the role of transforming growth factor-beta signaling in aortic disease in Marfan syndrome mice. more
thrombospondin 1
total:20
Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. 2009 to the paper
Acbam mouse monoclonal antibody against human and mouse thrombospondin-1 was used in immunohistochemistry to investigate the role of transforming growth factor Beta signaling in the regulation of tumor growth. more
TNC
tenascin C
total:12
Limbal epithelial crypt: a model for corneal epithelial maintenance and novel limbal regional variations. 2008 to the paper
Santa Cruz Biotechnology anti-tenascin C antibody was used to perform immunohistochemistry in order to study the distribution of cell membrane proteins and extracellular matrix proteins in human corneoscleral limbus rims. more
transthyretin
total:4
Hereditary lattice corneal dystrophy is associated with corneal amyloid deposits enclosing C-terminal fragments of keratoepithelin. 2005 to the paper
Dako polyclonal anti-transthyretin antibody was used in immunohistochemistry to study the association of hereditary lattice corneal dystrophy with corneal amyloid deposits enclosing C-terminal fragments of feratoepithelin. more
vitronectin
total:4
The effect of RGD peptides on osseointegration of hydroxyapatite biomaterials. 2008 to the paper
Santa Cruz vitronectin antibody was used in western blot in order to study the effect of RGD peptides on osseointegration of hydroxyapatite biomaterials more