Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
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total:3
UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) binds to alpha-actinin 1: novel pathways in skeletal muscle?. 2008 to the paper
Sigma monoclonal anti-alpha-actinin-2 antibody was used in immunohistochemistry to study the role for the binding of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) with alpha-actinin 1 in skeletal muscle. more
total:2
Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase. 2005 to the paper
FabGennix isoform-specific anti-adenylate cyclase antibody was used in western blot to study the effedt of interferon-gamma on adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia. more
total:2
Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. 2007 to the paper
Santa Cruz Biotechnology AC2 antibody was used in western blot to demonstrate stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. more
total:3
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Santa Cruz anti-adenylyl cyclase III antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
total:3
Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. 2007 to the paper
Santa Cruz Biotechnology anti-adenylate cyclase antibody was used in western blot to study the role of PDE3B and its interaction with PKB for regulation of specific cAMP pools and signalling pathways by insulin. more
total:7
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Santa Cruz Biotechnology anti-AKAP150 antibody was used in western blot in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
total:17
FCHo proteins are nucleators of clathrin-mediated endocytosis. 2010 to the paper
Transduction Laboratories mouse monoclonal anti-AP2A1 antibody was used to carry out western blot analysis in order to investigate the roles for FCHo1 and FCHo2 proteins in clathrin-mediated endocytosis in cell plasma membrane. more
total:5
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
Sigma anti-alpha-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. more
total:5
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1/2b antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
total:2
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. 2006 to the paper
BD Biosciences monoclonal anti-AP50 antibody was used in human HeLa cells or HUVECs and in western blot to study the role for clathrin adaptor AP2 in regulating thrombin receptor constitutive internalization and endothelial cell resensitization. more
total:8
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 to the paper
Santa Cruz Biotechnology anti-Braf antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation. more
total:13
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 to the paper
Affinity Bioreagents anti-phospho-CaMKII antibody was used for western blot in order to investigate the role of CaMKII in the regulation of pressure overload-induced cardiac hypertrophy to heart failure in mice. more
total:10
Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2. 2010 to the paper
Santa Cruz anti-phos-CaMKII antibody was used to perform western blot in order to study the role of cGMP-dependent protein kinase and RGS2 in local antihypertrophic effects of cardiac atrial natriuretic peptide. more
total:3
Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation. 2005 to the paper
Transduction Laboratories monoclonal anti-CaMKIV antibody was used in western blot and immunocytochemistry to study the presence of CaMKIV in mammalian sperm and its role in the regulation of human sperm motility. more
total:3
Elimination of rat spinal substance P receptor bearing neurons dissociates cardiovascular and nocifensive responses to nicotinic agonists. 2008 to the paper
Imran M. Khan (University of California, San Diego) rabbit polyclonal nAChR alpha3 subunit antibody was used in immunohistochemistry to further characterize intrathecal (IT) delivery of nicotinic agonists. more
total:5
Roles for nicotinic acetylcholine receptor subunit large cytoplasmic loop sequences in receptor expression and function. 2005 to the paper
Santa Cruz Biotechnology antibody H133 (rabbit anti-nAChR 4 subunit targeting amino acids 342 474) was used in immunoprecipitation to isolate the receptor protein nAChR from human SH-EP1 cells. more
total:2
Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. 2008 to the paper
Santa Cruz Biotechnology nAChR alpha5 antibody was used in western blot in order to study the role of nAChR in the pathogenesis of choroidal neovascularization (CNV) more
total:4
Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. 2008 to the paper
Santa Cruz Biotechnology nAChR beta2 antibody was used in western blot in order to study the role of nAChR in the pathogenesis of choroidal neovascularization (CNV) more
total:1
Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. 2008 to the paper
Santa Cruz Biotechnology nAChR beta3 antibody was used in western blot in order to study the role of nAChR in the pathogenesis of choroidal neovascularization (CNV)
total:1
Elimination of rat spinal substance P receptor bearing neurons dissociates cardiovascular and nocifensive responses to nicotinic agonists. 2008 to the paper
Imran M. Khan (University of California, San Diego) rabbit polyclonal nAChR beta4 subunit antibody was used in immunohistochemistry to further characterize intrathecal (IT) delivery of nicotinic agonists.
total:58
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB1 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:6
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. 2006 to the paper
Affinity BioReagents SAP97 antibody (1:3000) was used in western blot to demonstrate that dendritic A-type K+ channels regulate action potential backpropagation and the induction of specific forms of synaptic plasticity. more
total:2
Spectrin functions upstream of ankyrin in a spectrin cytoskeleton assembly pathway. 2006 to the paper
Developmental Studies Hybridoma Bank mouse anti-Dlg (discs large) antibody was used in western blot to test contributions of four specific functional sites in beta spectrin to its assembly and function. more
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:2
Vertebrate-specific sequences in the gephyrin E-domain regulate cytosolic aggregation and postsynaptic clustering. 2007 to the paper
Fritschy and Mohler GABAA receptor 1 antibody was used in immunocytochemistry to study the role of specific E-domain regions distinct from the known dimerization interface for controlling gephyrin aggregation. more
total:3
Altered sensitivities to morphine and cocaine in scaffold protein tamalin knockout mice. 2007 to the paper
Chemicon rabbit anti-GABAB2 (1:300) antibody was used in western blot to study how tamalin serves its physiological function in vivo. more
total:3
Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X. 2009 to the paper
Chemicon Inc.monoclonal anti-human alpha1 antibody (BD24) was used in western blot in order to study that GABAA receptor alpha1 subunit mutation, 975delC, S326fs328X induce the activation of NMD and ERAD which contribute to epileptogenesis. more
total:2
GABA(A) receptor downregulation in brains of subjects with autism. 2009 to the paper
Alpha Diagnostic International anti-GABAA receptor alpha 2 (GABRA2) antibody was used in western blot in order to demonstrate that GABAA receptors are reduced in three brain regions of subjects with autism more
total:1
GABA(A) receptor downregulation in brains of subjects with autism. 2009 to the paper
Alpha Diagnostic International GABAA receptor alpha 3 (GABRA3) antibody was used in western blot in order to demonstrate that GABAA receptors are reduced in three brain regions of subjects with autism
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GABA(A) receptor downregulation in brains of subjects with autism. 2009 to the paper
Alpha Diagnostic International anti-GABAA receptor beta 3 (GABRB3) antibody was used in western blot in order to demonstrate that GABAA receptors are reduced in three brain regions of subjects with autism more
total:2
Cellular distribution and subcellular localization of molecular components of vesicular transmitter release in horizontal cells of rabbit retina. 2005 to the paper
Dr.D. Pow gamma-aminobutyric acid antibody was used in immunohistochemistry (1:200) to study the distribution and subcellular localization of molecular components of vesicular transmitter release in horizontal cells of rabbit retina. more
total:12
Parallel memory processing by the CA1 region of the dorsal hippocampus and the basolateral amygdala. 2008 to the paper
Santa Cruz Biotechnology anti-pGluR1 antibdoy was used in western blot in order to investigate molecular correlates of IA consolidation in the hippocampus and the basolateral amygdala structures and their relation to NMDA receptors (NMDArs) and beta-adrenergic receptors (beta-ADrs) more
total:9
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. 2009 to the paper
Chemicon rabbit anti-GluR2 antibody was used in western blot and immunoprecipitation to investigate the role of dorsal horn GluR2 internalization in the regulation of NMDA receptor/PKC-dependent nociceptive hypersensitivity. more
total:5
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
Abcam rabbit anti-GNAI2 antibody was used to carry out immunoprecipitation assays in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
total:6
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-GNAI3 antibody was used to carry out immunoprecipitation assays in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
total:1
Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon. 2006 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-Galphagust antibody (I-20, sc-395) was used in immunohistochemistry to study the association of alpha-subunit of gustducin with PYY and GLP-1 in histological sections of the human colon.
total:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 to the paper
Dr. W. Simonds (NINDK) rabbit anti-VAChT antibody was used in western blot to study the localization and differential interaction of R7 RGS proteins with R7BP and R9AP in neurons of vertebrate retina.
total:3
Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking. 2006 to the paper
Millipore GluR3 antibody was used in western blot and immunoprecipitation to study the function of alsin gene. more
total:2
TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. 2005 to the paper
Upstate Biotechnology GluR4 antibody was used in western blot to study cell-autonomous role of TrkB in the establishment of hippocampal Schaffer collateral synapses. more
total:3
Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors. 2007 to the paper
Chemicon International rabbit polyclonal anti-mGluR5 antibody was used in immunocytochemistry to study the role of Homer 1a in neuronal functions. more
total:2
TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. 2005 to the paper
Upstate Biotechnology GluR6 antibody was used in western blot to study cell-autonomous role of TrkB in the establishment of hippocampal Schaffer collateral synapses. more
total:9
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. 2009 to the paper
Chemicon rabbit anti-NR2A antibody was used in western blot and immunoprecipitation to investigate the role of dorsal horn GluR2 internalization in the regulation of NMDA receptor/PKC-dependent nociceptive hypersensitivity. more
total:5
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. 2009 to the paper
Upstate rabbit anti-GRIP1 Ser880 antibody was used in western blot and immunoprecipitation to investigate the role of dorsal horn GluR2 internalization in the regulation of NMDA receptor/PKC-dependent nociceptive hypersensitivity. more
total:26
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Calbiochem/Merck anti-H-Ras antibody was used to perform western blot in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:2
Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir2.3 channels in HEK293 cells. 2007 to the paper
Alomone Labs anti-Kir2.1 antibody diluted to 1:2000 was used in western blot to study the role of Kir2.3 isoform in modifying channel sensitivity to pH in heterotetrameric channels. more
total:7
Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network. 2010 to the paper
Abcam KCNJ3/GIRK1 antibody(ab61191) was used to perform immunofluorescence in order to study transcriptional and epigenetic mechanisms of Wilms tumor. more
total:2
Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir2.3 channels in HEK293 cells. 2007 to the paper
Alomone Labs anti-Kir2.3 antibody diluted to 1:2000 was used in western blot to study the role of Kir2.3 isoform in modifying channel sensitivity to pH in heterotetrameric channels. more
total:1
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension. 2011 to the paper
Sigma antibody polyclonal anti-KCNJ5 antibody was used to perform immunohistochemistry and western blot in order to study the expression of KCNJ5 in adrenal glomerulosa.
total:5
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
BD Biosciences anti-Bir1 antibody was used to carry out ChIP assays in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
total:5
MLC1 is associated with the dystrophin-glycoprotein complex at astrocytic endfeet. 2007 to the paper
USBiological polyclonal antibody against Kir4.1 was used in immunoprecipitation and western blot to isolate and detect Kir4.1 in human brain lysates, and in immunohistochemistry to detect aquaporin-4 distribution in human brain tissues and human glioblastoma multiforme tissues from MLC patients more
total:38
TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. 2010 to the paper
Calbiochem anti-Hdm2 antibody was used for western blot in order to investigate the role of TGFB1 in the regulation of Mdm2 expression and late-stage breast cancer metastasis. more
total:2
Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility. 2007 to the paper
Sigma mouse anti-myosin VI antibody was used to carry out western blot analysis in order to investigate the role for UNC-45 in the regulation of tumor cell proliferation and metastasis. more
total:20
The geometric structure of the brain fiber pathways. 2012 to the paper
Abcam mouse monoclonal anti-Neurofilament was used at 1:1000 to perform immunohistochemistry in order to show the architecture of the brain fiber pathways. more
total:21
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. 2009 to the paper
Chemicon rabbit anti-NR1 antibody was used in western blot and immunoprecipitation to investigate the role of dorsal horn GluR2 internalization in the regulation of NMDA receptor/PKC-dependent nociceptive hypersensitivity. more
total:10
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. 2009 to the paper
Chemicon rabbit anti-NR2B antibody was used in western blot and immunoprecipitation to investigate the role of dorsal horn GluR2 internalization in the regulation of NMDA receptor/PKC-dependent nociceptive hypersensitivity. more
total:4
Mechanisms of Chlamydia trachomatis entry into nonphagocytic cells. 2007 to the paper
Chemicon anti-NSF antibody was used to carry out immunofluorescence assays in order to investigate the mechanism of entry for Chlamydia trachomatis into nonphagocytic cells. more
total:20
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Santa Cruz anti-RSK-1 antibody (1:1,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediates anti-apoptotic effects. more
total:3
The estrogen and c-Myc target gene HSPC111 is over-expressed in breast cancer and associated with poor patient outcome. 2008 to the paper
Santa Cruz Biotechnology PICK-1 antibody was used in chromatin immunoprecipitation assays in order to study the role of estrogen-target genes in initiation and progression of breast cancer more
total:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-PKCAalpha antibody was used in western blot in order to study the function of TMX3 in eye development. more
total:27
Protein kinase C in porcine retinal arteries and neuroretina following retinal ischemia-reperfusion. 2009 to the paper
Santa Cruz Biotechnology mouse monoclonal anti-beta-actin antibody (1:5000) was used for western blot in order to investigate the role of PKC in the regulation of porcine retinal ischemia-reperfusion. more
total:3
Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. 2005 to the paper
Santa Cruz Biotechnology PLC beta2 antibody was used in western blot to study localization of TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells more
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 to the paper
Santa Cruz Biotechnology anti-the catalytic D subunit of PKA antibody C-20 was used in human fibrosarcoma HT1080 cells and in western blot to study the role for tyrosine phosphorylation in full-scale activation of the eIF2alpha RNA-dependent protein kinase. more
total:12
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. 2007 to the paper
Cell Signaling Technology phospho-Pan-PKC antibody (1:1,000) was used in western blot to study melanoma cell motility by the Wnt5A/protein kinase C pathway through the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition more
total:24
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
Thermo Scientific monoclonal anti-PSD-95 antibody was used to carry out western blot analysis and immunofluorescence assays in order to determine the atomic structure of human adenovirus. more
total:46
MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. 2010 to the paper
Santa Cruz Biotechnology anti-RAF1 antibody was used to perform western blot in order to study the role of microRNA-7 in tongue squamous cell carcinoma cells. more
total:9
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 to the paper
Cell Signaling anti-phosphorylated p90RSK antibody was used to perform western blot in order to study the important role of GRK4 in D3 receptor's signaling in human proximal tubule cells. more
total:9
Mitogen-activated protein kinase-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection. 2009 to the paper
Santa Cruz anti-RSK2 antibody was used to perform western blot in order to study the role of RSK2 in the cellular antiviral response. more
total:1
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. 2009 to the paper
Upstate rabbit anti-stargazin antibody was used in western blot and immunoprecipitation to investigate the role of dorsal horn GluR2 internalization in the regulation of NMDA receptor/PKC-dependent nociceptive hypersensitivity.