NOTCH2 Activation and Transmission of Signal to the Nucleus
gene
reagent
sample publication
sample review
total:10
S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10. 2009 to the paper
Chemicon ADAM-10 antibody was used for western blot in order to indentify new biomarker of Alzheimer's disease. more
total:2
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors. 2005 to the paper
Santa Cruz Biotechnology polyclonal anti-Delta1 antibody (sc-8155) was used in immunohistochemistry to study the effect of Delta1 versus Jagged1 on T-cell progenitors at specific developmental stages in sections from human thymic tissue. more
total:1
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. 2007 to the paper
I. B. Lobov (Regeneron Pharmaceuticals) Dll4 antibody was used in immunohistochemistry to study the role of Dll4 during vascular growth and differentiation.
total:2
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
Santa Cruz Biotechnologies Biosystems anti-JAGGED2 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:12
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
R&D Systems anti-Jagged1 antibody was used to perform flow cytometry in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
total:10
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 to the paper
Calbiochem rabbit anti-nicastrin antibody was used to perform western blot in order to study the effect of TNF-alpha on gamma-secretase. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more