NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
gene
reagent
sample publication
sample review
caspase-10
caspase 10
total:9
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. 2006 to the paper
R & D Systems anti-caspase-10 antibody was used in human THP-1 cells and in western blot to study the roles for the interaction of the B30.2 domain of pyrin, the familial mediterranean fever protein with caspase-1 in IL-1 production. more
caspase-8
caspase 8
total:73
Detachment of esophageal carcinoma cells from extracellular matrix causes relocalization of death receptor 5 and apoptosis. 2009 to the paper
R&D systems anti-casp8 antibody was used to carry out western blot analysis in order to investigate the mechanism of DR5 relocalization and its effect on cell apoptosis during adhesion to detachment of EC9706 cells. more
DDX58
DExD/H-box helicase 58
total:1
Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling. 2008 to the paper
ABGENT anti-RIG-I antibody was used to perform western blot in order to study the cellular signaling elicited by human metapneumovirus in airway epithelial cells.
FADD
Fas associated via death domain
total:19
Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis. 2008 to the paper
Cell Signaling Technology anti-FADD antibody was used to perform western blot in order to assess the effect of Rk1 on cell viability and telomerase activity. more
IFIH1
interferon induced with helicase C domain 1
total:2
Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling. 2008 to the paper
IMGENEX anti-MDA-5 antibody was used to perform western blot in order to study the cellular signaling elicited by human metapneumovirus in airway epithelial cells. more
IKK alpha
component of inhibitor of nuclear factor kappa B kinase complex
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-IKKalpha monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
IKKbeta
inhibitor of nuclear factor kappa B kinase subunit beta
total:36
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Millipore anti-IKK2 antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
IKKgamma
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
total:21
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Santa Cruz Biotechnology anti-NEMO antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
MAVS
mitochondrial antiviral signaling protein
total:1
Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria. 2009 to the paper
Cell Signaling Technology rabbit polyclonal anti-VISA antibody was used in western blot to study the effect of gC1qR on RIG-I and MDA5-dependent antiviral response at mitochondria.
RIP
receptor interacting serine/threonine kinase 1
total:9
Repression of NF-kappaB and activation of AP-1 enhance apoptosis in prostate cancer cells. 2009 to the paper
Santa Cruz Biotechnology anti-RIP antibody was used in western blot to study the effect of repression of NF-kB and activation of AP-1 on apoptosis in prostate cancer cells. more