NCAM signaling for neurite out-growth
gene
reagent
sample publication
sample review
14 3 3 protein beta alpha
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
total:9
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3beta antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
CACNA1C
calcium voltage-gated channel subunit alpha1 C
total:11
The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. 2010 to the paper
Chemicon anti-CaV1.2 antibody was used to carry out western blot analysis in order to investigate the role for STIM1 in coordinating Voltage- and store-operated calcium channels to generate coherent calcium signals. more
CACNA1D
calcium voltage-gated channel subunit alpha1 D
total:3
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav1.3 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels. more
CACNA1G
calcium voltage-gated channel subunit alpha1 G
total:1
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav3.1 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels.
CACNA1I
calcium voltage-gated channel subunit alpha1 I
total:1
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav3.3 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels.
CACNB1
calcium voltage-gated channel auxiliary subunit beta 1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
CD56
neural cell adhesion molecule 1
total:56
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. 2012 to the paper
eBioscience anti-CD56 eFluor780 was used to perform flow cytometry in order to show that commensal bacteria was restricted in specific sites by innate lymphoid cells more
Cdc2
cyclin dependent kinase 1
total:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk1 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
COL4A1
collagen type IV alpha 1 chain
total:9
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. 2010 to the paper
Abcam anti Col IV antibody was used to perform immunohistochemistry in order to study the function of the astrocytic antigen aquaporin 4 (AQP-4) in inflammatory demyelinating diseases. more
COL4A3
collagen type IV alpha 3 chain
total:5
Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. 2005 to the paper
Santa Cruz Biotechnology goat anti-alpha3 antibody was used in western blot to study the effect of activation of vascular endothelial growth factor receptor 3 on endothelial function and infection. more
COL4A4
collagen type IV alpha 4 chain
total:2
ELR-negative CXC chemokine CXCL11 (IP-9/I-TAC) facilitates dermal and epidermal maturation during wound repair. 2008 to the paper
Abcam rabbit polyclonal collagen IV antibody was used in immunohistochemistry in order to study the role of IP-10 and IP-9 in epidermal maturation during wound repair more
COL6A1
collagen type VI alpha 1 chain
total:2
The extracellular matrix glycoprotein elastin microfibril interface located protein 2: a dual role in the tumor microenvironment. 2010 to the paper
Santa Cruz Biotechnology anti-type I collagen antibody was used in western blot in order to investigate the function of the 90-amino acid residue fragment of elastin microfibril interface located protein 2 (EMILIN2) in the tumor microenvironment. more
COL9A1
collagen type IX alpha 1 chain
total:2
Alteration of medial-edge epithelium cell adhesion in two Tgf-beta3 null mouse strains. 2008 to the paper
Developmental Studies Hybridoma Bank 1:50 monoclonal mouse IgG anti-sheep collagen IX antibody was used in immunohistochemistry in order to study the role of growth factor TGF-b3 in palatal shelf adhesion more
CREB
cAMP responsive element binding protein 1
total:58
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB1 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
ERK1
mitogen-activated protein kinase 3
total:252
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Millipore anti-ERK1/2 polyclonal antibody (1:10,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediated anti-apoptotic effects. more
ERK2
mitogen-activated protein kinase 1
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
FAK
protein tyrosine kinase 2
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
FGFR1
fibroblast growth factor receptor 1
total:17
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Biosource International anti-FGFR-1 (pYpY653/654) antibodies were used to perform western blot and ELISA analyses in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
Fyn
FYN proto-oncogene, Src family tyrosine kinase
total:19
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-FYN antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking. more
GDNF
glial cell derived neurotrophic factor
total:4
Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease. 2005 to the paper
Santa Cruz anti-GDNF antibody was used in immunohistochemistry to compare GDNF, BDNF, or both, for their capabilities to correct behavioral deficits and protect nigrostriatal dopaminergic neurons in a rat model of PD.. more
GFRA1
GDNF family receptor alpha 1
total:5
Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation. 2006 to the paper
R & D Systems anti-GFR1 (1:1000) was used in western blot to demonstrate that lipid rafts sequester Ret away from the degradation machinery to sustain Ret signaling. more
GFRA2
GDNF family receptor alpha 2
total:4
MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells. 2008 to the paper
Cell Signaling anti-P-p38 antibody was used to perform western blot in order to investigate the role of the MAPK kinase kinase-1 (MEKK-1) in cytokine-induced signaling pathway. more
Grb2
growth factor receptor bound protein 2
total:36
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal against Ron antibody was used in western blot in order to demostrate the expression of PAX 5 and the regulation for c-Met transcription in small cell lung cancer. more
H-Ras
HRas proto-oncogene, GTPase
total:26
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Calbiochem/Merck anti-H-Ras antibody was used to perform western blot in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
MEK1
mitogen-activated protein kinase kinase 1
total:57
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Cell Signaling Technology anti-MEK1 antibody was used to perform flow cytometry and immunochemistry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
MEK2
mitogen-activated protein kinase kinase 2
total:16
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. 2010 to the paper
Cell Signaling Technologies anti-phospho-MEK1/2 antibody was used to perform western blot in order to study the discrimination between the yeast and hyphal forms of C. albicans in epithelial cells via a biphasic MAPK response. more
NRAS
NRAS proto-oncogene, GTPase
total:4
Selectively oncolytic mutant of HSV-1 lyses HeLa cells mediated by Ras/RTN3. 2007 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-Ras antibody was used in western blot to study mechanism mtHSV was targeted for treating tumors but not other organs. more
prion protein
total:17
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Chemicon anti-Prion Protein was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
Raf-1
Raf-1 proto-oncogene, serine/threonine kinase
total:46
MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. 2010 to the paper
Santa Cruz Biotechnology anti-RAF1 antibody was used to perform western blot in order to study the role of microRNA-7 in tongue squamous cell carcinoma cells. more
Ras
KRAS proto-oncogene, GTPase
total:20
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Oncogene Ras antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
RPS6KA5
ribosomal protein S6 kinase A5
total:3
Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation. 2009 to the paper
Santa Cruz Biotechnology MSK1 antibody was used in western blot in order to study the role of MSK1 in NF-kB activation and inflammatory diseases more
Sos
SOS Ras/Rac guanine nucleotide exchange factor 1
total:11
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 to the paper
Santa Cruz rabbit Sos-1 antibody was used in western blot to study the role of Abi-1 in morphogenesis and synapse formation. more
SPTA1
spectrin alpha, erythrocytic 1
total:6
Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease. 2005 to the paper
Chemicon anti-spectrin antibody was used in western blot in order to investigate the molecular mechanism of beta-amyloid induced significant decrease of dynamin1. more
SPTA1
spectrin alpha, erythrocytic 1
total:6
Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease. 2005 to the paper
Chemicon anti-spectrin antibody was used in western blot in order to investigate the molecular mechanism of beta-amyloid induced significant decrease of dynamin1. more
SPTBN4
spectrin beta, non-erythrocytic 4
SPTBN4
spectrin beta, non-erythrocytic 4
Src
SRC proto-oncogene, non-receptor tyrosine kinase
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STX
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
TAG-1
contactin 2
total:8
Human T-cell leukemia virus type 1 oncoprotein tax represses ZNF268 expression through the cAMP-responsive element-binding protein/activating transcription factor pathway. 2008 to the paper
Epitomics anti-Tax monoclonal antibody was used to perform EMSA in order to show that ZNF268 expression can be inhibited by HTLV-1 Tax. more