Metabolism
gene
reagent
sample publication
sample review
3 hydroxyisobutyrate dehydrogenase
3-hydroxyisobutyrate dehydrogenase
total:1
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 to the paper
ViroStat anti-NS5a antibody was used to perform western blot in order to study the role of non-directed activity-based protein profiling plays in the identification of enzymes that are either predominantly or exclusively labeled in living cells.
6 phosphofructo 2 kinase fructose 2 6 bisphosphatase
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
total:2
Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases. 2009 to the paper
Novus Biologicals mouse anti-PFKFB3 (number H00005209-A01 and H00005209-M08) polyclonal and monoclonal antibodies were used to perform western blot in order to demonstrate that overexpression of 6-phosphofructo-2-kinase (PFKFB3) in the nuclear increases cell proliferation via cyclin-dependent kinases. more
ABC7
ATP binding cassette subfamily B member 7
ABCA1
ATP binding cassette subfamily A member 1
total:10
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Abcam mouse monoclonal anti-ABCA1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
ABCB1
ATP binding cassette subfamily B member 1
total:15
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 to the paper
Santa Cruz Biotechnology MDR1 antibody (1:500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells. more
ABCB11
ATP binding cassette subfamily B member 11
total:3
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Kamiya Biomedical rabbit anti-Bsep antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes. more
ABCB4
ATP binding cassette subfamily B member 4
total:1
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Signet Laboratories mouse anti-MDR antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes.
ABCC5
ATP binding cassette subfamily C member 5
ABCG1
ATP binding cassette subfamily G member 1
total:6
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Novus rabbit polyclonal anti-ABCG1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
ABCG2
ATP binding cassette subfamily G member 2 (Junior blood group)
total:7
Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma. 2010 to the paper
Abcam anti-ABCG2 antibody was used to perform western blot in order to study the role of LMP2A in the nasopharyngeal carcinoma progression. more
ABCG5
ATP binding cassette subfamily G member 5
ABCG8
ATP binding cassette subfamily G member 8
ABHD5
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
ACACA
acetyl-CoA carboxylase alpha
total:17
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-ACC1 S79ph antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
ACADSB
acyl-CoA dehydrogenase short/branched chain
ACAT1
acetyl-CoA acetyltransferase 1
total:2
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. 2009 to the paper
Cayman ACAT-1 antibody was used for western blot in order to investigate the role of mitochondria in endothelial cell dysfunction. more
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
ACO2
aconitase 2
total:1
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. 2009 to the paper
ABGEN aconitase-2 antibody was used for western blot in order to investigate the role of mitochondria in endothelial cell dysfunction.
ACP5
acid phosphatase 5, tartrate resistant
total:1
Increased tartrate-resistant acid phosphatase (TRAP) expression in malignant breast, ovarian and melanoma tissue: an investigational study. 2006 to the paper
Novocastra Laboratories Ltd. TRAP monoclonal antibody against against the N-terminal portion of human TRAP (clone: 26E5, subtype: IgG2b) was used in immunocytochemistry and immunohistochemistry to study the TRAP expression in various malignant and benign breast, ovarian, and melanoma tissues.
ACSL1
acyl-CoA synthetase long chain family member 1
ACSL3
acyl-CoA synthetase long chain family member 3
total:1
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate. 2008 to the paper
Novus Biologicals anti-Facl3 antibody was used for western blot in order to investigate the roles of elenium and isoflavones in the regulation of androgen-regulated gene expression in healthy rat dorsolateral prostate.
ACSL4
acyl-CoA synthetase long chain family member 4
ACSL6
acyl-CoA synthetase long chain family member 6
ACSM2A
acyl-CoA synthetase medium chain family member 2A
ACSM4
acyl-CoA synthetase medium chain family member 4
ACSM5
acyl-CoA synthetase medium chain family member 5
ACSS1
acyl-CoA synthetase short chain family member 1
ADCY1
adenylate cyclase 1
total:2
Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase. 2005 to the paper
FabGennix isoform-specific anti-adenylate cyclase antibody was used in western blot to study the effedt of interferon-gamma on adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia. more
ADCY2
adenylate cyclase 2
total:2
Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. 2007 to the paper
Santa Cruz Biotechnology AC2 antibody was used in western blot to demonstrate stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. more
ADCY3
adenylate cyclase 3
total:3
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Santa Cruz anti-adenylyl cyclase III antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
ADCY5
adenylate cyclase 5
total:3
Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. 2007 to the paper
Santa Cruz Biotechnology anti-adenylate cyclase antibody was used in western blot to study the role of PDE3B and its interaction with PKB for regulation of specific cAMP pools and signalling pathways by insulin. more
AE1
solute carrier family 4 member 1 (Diego blood group)
total:5
Adenomatoid tumour of the liver. 2008 to the paper
Labvision anti-AE1 antibody was used to perform immunohistochemistry in order to study the adenomatoid tumour of the liver. more
aggrecan
total:4
Expression of ZIC family genes in meningiomas and other brain tumors. 2010 to the paper
Sigma anti-chondroitin sulfate proteoglycan antibody was used to perform immunohistochemistry in order to study the expression of the ZIC family genes in different type of brain tumors. more
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5
GPAT3
glycerol-3-phosphate acyltransferase 3
AGT
angiotensinogen
total:6
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 to the paper
IgG corporation rabbit polyclonal anti-ang II serum was used in immunohistochemistry in order to study the glomerular AGT's expression and its correlation with expression of other RAS components more
AK2
adenylate kinase 2
total:1
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. 2010 to the paper
Novocastra anti-NCL-L-AK2 antibody was used in western blot in order to investigate the different expression levels of spindle proteins in the testicular germ cell tumors.
AK5
adenylate kinase 5
total:1
Adenylate kinase 5 autoimmunity in treatment refractory limbic encephalitis. 2007 to the paper
ABGENT rabbit anti-AK5 polyclonal antibody(1:50) was used to perform immunohistochemistry in order to study the autoimmunity of AK5 in treatment refractory LE patients.
AKAP79
A-kinase anchoring protein 5
total:7
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Santa Cruz Biotechnology anti-AKAP150 antibody was used in western blot in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
AKR1D1
aldo-keto reductase family 1 member D1
total:1
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. 2009 to the paper
Abcam anti-AKR1D1 antibody was used to perform western blot in order to study the novel BRAF fusion gene in 7q34 duplication of pediatric low-grade astrocytomas detected by high density SNP-based genotype array analysis.
Akt
AKT serine/threonine kinase 1
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
albumin
total:11
Human microglial cells synthesize albumin in brain. 2008 to the paper
R&D system mouse anti-human-albumin antibody was used in immunohistochemistry and immunocytochemistry in order to study the expression of albumin in human microglial cells and brain tissues. more
ALDH1A1
aldehyde dehydrogenase 1 family member A1
total:2
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Epitomics anti-Aldh1 antibody (1:150) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
ALOX12
arachidonate 12-lipoxygenase, 12S type
total:2
Role of 12-lipoxygenase in volatile anesthetic-induced delayed preconditioning in mice. 2006 to the paper
Cayman Chemical 12-LO primary antibody was used in western blot to study the role of 12-lipoxygenase in volatile anesthetic-induced delayed preconditioning in mice. more
ALOX5
arachidonate 5-lipoxygenase
total:6
A mutant of hepatitis B virus X protein (HBxDelta127) promotes cell growth through a positive feedback loop involving 5-lipoxygenase and fatty acid synthase. 2010 to the paper
Santa Cruz Biotechnology anti-5-LOX antibody was used to perform western blotting in order to study how the cell growth are promoted by research on a mutant of HBx. more
alpha L iduronidase
alpha-L-iduronidase
total:1
Intrathecal administration of AAV vectors for the treatment of lysosomal storage in the brains of MPS I mice. 2006 to the paper
BioMarin Pharmaceutical rabbit polyclonal IDUA antibody was used in immunohistochemistry (1:3000) to determine the expression level of IDUA in the brain after AAV vectors.
AMACR
alpha-methylacyl-CoA racemase
total:3
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer. 2008 to the paper
Dako anti-AMACR(13H4) antibody was used to perform immunohistochemistry in order to study the expression of cytokeratin 7 and 19 are related with genomic stability and favorable prognosis in clear cell renal cell cancer. more
AMY2A
amylase alpha 2A
total:3
GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation. 2009 to the paper
Neomarkers rabbit anti-alpha-amylase antibody was used to carry out immunofluorescence assays in order to investigate the regulation of Gli1 transcription and its role in pancreatic ductal adenocarcinoma cell survival and transforming phenotype. more
ANGPTL4
angiopoietin like 4
total:1
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. 2005 to the paper
Karen S. L. Lam (University of Hong Kong, China) monoclonal ANGPTL4 antibody was used in ELISA to study its effect in mice
apoA-I
apolipoprotein A1
total:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 to the paper
Abcam polyclonal rabbit anti-apoA-I antibody (1:10,000) was used for western blot in order to investigate the distinct roles of apolipoprotein components in a transgenic mouse model. more
APOA4
apolipoprotein A4
total:1
The expression of intact and mutant human apoAI/CIII/AIV/AV gene cluster in transgenic mice. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal human apoAIV antibody was used in western blot to study the expression of human apoAI/CIII/AIV/AV in transgenic mice
APOC2
apolipoprotein C2
total:2
Serum amyloid P colocalizes with apolipoproteins in human atheroma: functional implications. 2007 to the paper
Calbiochem rabbit polyclonal apoC-II antibody was used in immunohistochemistry to study the colocalization of serum amyloid P with apolipoproteins in human atheroma more
ApoE
apolipoprotein E
total:19
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Calbiochem anti-ApoE antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
apolipoprotein B
total:14
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Abcam anti-ApoB100 antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
AQP1
aquaporin 1 (Colton blood group)
total:8
Close association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains. 2008 to the paper
Santa Cruz Biotechnology anti-AQP1 antibody (H-55) was used in immunocytochemistry and western blot to detect AQP1 expression in human astrocytes, and in immunohistochemistry to investigate AQP1 expression in cerebral cortex from AD patients. more
ARF1
ADP ribosylation factor 1
total:8
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. 2007 to the paper
Affinity Bioreagents anti-Arf antibody was used to perform western blot in order to study the interaction between Arf and Poliovirus Protein 3CD and its effect on poliovirus replication. more
ARG1
arginase 1
total:2
Hepatitis C virus targets over-expression of arginase I in hepatocarcinogenesis. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-arginase 1 antibody was used in western blot and immunohistochemistry to study the role for elevated arginase expression in HCV associated HCC more
aromatase
cytochrome P450 family 19 subfamily A member 1
total:4
GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome. 2008 to the paper
Santa Cruz Biotechnology goat anti-CYP19 (1:200) polyclonal antibody was used to perform immunohistochemistry in order to study the physiological functions of GPRC6A. more
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ATP citrate lyase
total:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 to the paper
Epitomics anti-ATP-citrate lyase antibody was used to perform western blot in order to study the cytotoxicity of timosaponin AIII towards tumor cells.
ATP5F1A
ATP synthase F1 subunit alpha
total:3
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD. 2008 to the paper
Santa Cruz Biotechnologies anti-F1-ATPase was used to perform western blot in order to demonstrate that OS-9 and XTP3-B/erlectin are ER-resident glycoproteins that bind to ERAD substrates and, via the SEL1L adaptor, to the ER membrane-embedded ubiquitin ligase Hrd1. more
ATP5F1B
ATP synthase F1 subunit beta
total:2
MCU encodes the pore conducting mitochondrial calcium currents. 2013 to the paper
Abcam anti-ATP5B antibody was used to perform western blot in order to investigate the functional property of the MCU gene. more
ATP5F1D
ATP synthase F1 subunit delta
total:1
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. 2009 to the paper
Affinity BioReagents ATP synthase antibody was used for western blot in order to investigate the role of mitochondria in endothelial cell dysfunction.
ATP5PB
ATP synthase peripheral stalk-membrane subunit b
ATP5PO
ATP synthase peripheral stalk subunit OSCP
total:1
ATP6 homoplasmic mutations inhibit and destabilize the human F1F0-ATP synthase without preventing enzyme assembly and oligomerization. 2007 to the paper
Mitosciences anti-OSCP antibody was used in western blot to study the effect of ATP6 homoplasmic mutations on the human F1F0-ATP synthase
DMAC2L
distal membrane arm assembly complex 2 like
ATP6
ATP synthase F0 subunit 6
ATP8
ATP synthase F0 subunit 8
AUH
AU RNA binding methylglutaconyl-CoA hydratase
B3GALT6
beta-1,3-galactosyltransferase 6
total:1
Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease. 2010 to the paper
Abnova anti-B3GALT6(M06) mouse monoclonal antibody was used to perform western blot in order to study the efficiency of using the small interfering RNA(siRNA) to control expression of particular genes involved in GAG synthesis for the treatment of mucopolysaccharidosis type III.
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
total:1
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
Invitrogen anti-Core1 antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA.
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
B4GALT7
beta-1,4-galactosyltransferase 7
total:1
Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease. 2010 to the paper
Proteintech Group anti-B4GALT7 rabbit polyclonal antibody was used to perform western blot in order to study the efficiency of using the small interfering RNA(siRNA) to control expression of particular genes involved in GAG synthesis for the treatment of mucopolysaccharidosis type III.
BAAT
bile acid-CoA:amino acid N-acyltransferase
BCAT1
branched chain amino acid transaminase 1
BCKDHA
branched chain keto acid dehydrogenase E1 subunit alpha
biotinidase
total:1
Differential profiling of breast cancer plasma proteome by isotope-coded affinity tagging method reveals biotinidase as a breast cancer biomarker. 2010 to the paper
GeneTex anti-BTB antibody was used to perform western blot in order to reveal that biotinidase was a breast cancer biomarker by isotope-coded affinity tagging method.
BMP1
bone morphogenetic protein 1
total:1
Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation. 2005 to the paper
Affinity Bioreagents polyclonal anti-BMP-1 antibody (recognizing the CUB-2 domain) was used in western blot to study the binding of cellular fibronectin with lysyl oxidase
BRIP1
BRCA1 interacting protein C-terminal helicase 1
total:2
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Bethyl Laboratories anti-FANCJ was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
CA9
carbonic anhydrase 9
total:4
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. 2007 to the paper
Santa Cruz anti-CAIX antibody was used to perform western blot in order to study the dependency on oxidative phosphorylation during transformation of human mesenchymal stem cells. more
CACNA1A
calcium voltage-gated channel subunit alpha1 A
total:1
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav2.1 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels.
CACNA1C
calcium voltage-gated channel subunit alpha1 C
total:11
The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. 2010 to the paper
Chemicon anti-CaV1.2 antibody was used to carry out western blot analysis in order to investigate the role for STIM1 in coordinating Voltage- and store-operated calcium channels to generate coherent calcium signals. more
CACNA1D
calcium voltage-gated channel subunit alpha1 D
total:3
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav1.3 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels. more
CACNA1E
calcium voltage-gated channel subunit alpha1 E
total:1
Voltage-dependent calcium channels of dog basilar artery. 2007 to the paper
Alomone Laboratories polyclonal rabbit Cav2.3 antibody was used in western blot to study the electrophysiological and molecular characteristics of voltage-dependent calcium (Ca (2+) channels.
CACNA2D2
calcium voltage-gated channel auxiliary subunit alpha2delta 2
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
total:1
Nuclear localization and mitogen-activated protein kinase phosphorylation of the multifunctional protein CAD. 2005 to the paper
Santa Cruz Biotechnology polycolonal goat CAD Thr (P) 456 antibodie was used in western blot to study phosphorylation of the multifunctional protein CAD by nuclear localization and mitogen-activated protein Kinase.
CARM1
coactivator associated arginine methyltransferase 1
total:3
The C-terminal domain of RNA polymerase II is modified by site-specific methylation. 2011 to the paper
Bethyl Laboratories anti-CARM1 antibody was used to perform immunocytochemistry in order to reveal that methylation of the carboxy-terminal domain of RNA polymerase II facilitates the expression of some RNAs. more
catalase
total:8
Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma. 2009 to the paper
Calbiochem rabbit polyclonal anti-catalase was used to perform western blot in order to show that ROS production and PDK2 upregulation induced by mitochondrial ND2 mutation lead to HIF1alpha accumulation in head and neck squamous cell carcinoma. more
caveolin-1
caveolin 1
total:60
Xp11.2 translocation renal cell carcinoma occurring during pregnancy with a novel translocation involving chromosome 19: a case report with review of the literature. 2009 to the paper
Epitomics anti-calveolin-1 antibody was used for immunohistochemistry in order to show that a novel translocation involving chromosome 19 causes Xp11.2 translocation renal cell carcinoma. more
CBP
CREB binding protein
total:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 to the paper
Santa Cruz Biotechnology anti-CBP antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathway more
CBR1
carbonyl reductase 1
total:2
Differential expression of prostaglandin (PG) synthesis enzymes in conceptus during peri-implantation period and endometrial expression of carbonyl reductase/PG 9-ketoreductase in the pig. 2007 to the paper
Abcam 1:2000 polyclonal anti-human CBR1 antibody was used in western blot to study the role of prostaglandins (PGs) in luteolysis, maternal recognition of pregnancy, and implantation. more
CD147
basigin (Ok blood group)
total:15
Upregulation of EMMPRIN after permanent focal cerebral ischemia. 2008 to the paper
Serotec rat anti-EMMPRIN monoclonal antibody (1:200) was used in immunohistochemistry in order to examine potential association between EMMPRIN and MMP-9 expre more
CD36
CD36 molecule
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
CD44
CD44 molecule (Indian blood group)
total:49
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 to the paper
Millipore rat anti-heparan sulfate proteoglycan monoclonal antibody was used to perform immunohistochemistry in order to investigate the role of sFLT-1 in the maintenance of the avascular photoreceptor layer in mouse models. more
CD57
beta-1,3-glucuronyltransferase 1
total:9
Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival. 2008 to the paper
Becton Dickinson anti-CD57 antibody was used in immunohistochemistry to investigate the relationship between IDO expression and tumor-infiltrating lymphocytes in endometrial cancer. more
CD73
5'-nucleotidase ecto
total:12
Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. 2010 to the paper
Hycult Biotechnology mouse anti-human CD73 (1:50) antibody was used to perform immunohistochemistry in order to show that the adenosine metabolism and signaling in the lungs of patients with COPD and IPF are altered. more
CEPT1
choline/ethanolamine phosphotransferase 1
CERS5
ceramide synthase 5
total:1
LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia. 2005 to the paper
Sigma Chemical monoclonal anti-V5 peroxidase-conjugated antibody was used in western blot to demonstrate that LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia
CHD9
chromodomain helicase DNA binding protein 9
choline acetyltransferase
choline O-acetyltransferase
total:8
Sustained expression of TDP-43 and FUS in motor neurons in rodent's lifetime. 2010 to the paper
Millipore goat ChAT antibody was used to perform immunohistochemistry in order to clarify important roles of TDP-43 and FUS in motor neurons to the selectivity of the neurotoxicity. more
chondroitin 6 sulfotransferase
carbohydrate sulfotransferase 3
total:2
Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase. 2005 to the paper
ICN Biomedicals 20-HSD antiserum (1:1000) was used in western blot to determine the relative contribution of 20alpha-HSD to progesterone metabolism and Stat5 function during pregnancy and parturition. more
CHST7
carbohydrate sulfotransferase 7
CHST9
carbohydrate sulfotransferase 9
CIAO1
cytosolic iron-sulfur assembly component 1
connective tissue growth factor
cellular communication network factor 2
total:11
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Santa Cruz Biotechnologies CTGF antibody (1:2,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
COQ5
coenzyme Q5, methyltransferase
COX-1
cytochrome c oxidase subunit I
total:12
MCU encodes the pore conducting mitochondrial calcium currents. 2013 to the paper
Abcam mouse anti-MTCO1 antibody was used to perform immunocytochemistry in order to investigate the functional property of the MCU gene. more
COX-2
cytochrome c oxidase subunit II
total:26
Fatty acids identified in the Burmese python promote beneficial cardiac growth. 2011 to the paper
Novus Biologicals mouse anti-human MTCO2 (COX2) was used in 2ug/ml to perform mitochondrial staining in order to show that beneficial heart growth could be promoted by fatty acids from Burmese python. more
COX10
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
total:1
Mechanism of mitomycin-induced apoptosis in cultured corneal endothelial cells. 2008 to the paper
Santa Cruz Biotechnology cytochrome c antibody was used in western blot in order to investigate whether MMC induces cellular apoptosis in corneal endothelial cells
COX15
cytochrome c oxidase assembly homolog COX15
total:8
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-cytochrome c antibody was used to perform immunocytochemistry in order to study the protective autophagy involved in trail resistance of apoptosis-defective tumor cells. more
COX3
cytochrome c oxidase III
COX4I1
cytochrome c oxidase subunit 4I1
total:11
PUMA- and Bax-induced autophagy contributes to apoptosis. 2009 to the paper
Molecular Probes anti-COXIV antibody was used to perform western blot in order to study a role for PUMA or Bax-induced mitochondrial autophagy in the promotion of apoptosis. more
COX6B1
cytochrome c oxidase subunit 6B1
total:1
The mitochondrial disulfide relay system protein GFER is mutated in autosomal-recessive myopathy with cataract and combined respiratory-chain deficiency. 2009 to the paper
Molecular Probes anti-COX6B1 antibody was used to perform immunocytochemistry in order to study the mechanisms of mitochondrial biogenesis and the roles of GFER in the human DRS.
CPS1
carbamoyl-phosphate synthase 1
total:1
The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1. 2008 to the paper
Abcam CPS1 antibody was used in immunohistochemistry to characterize the Hep Par 1 antigen.
CPT2
carnitine palmitoyltransferase 2
total:1
Coimmunoprecipitation of FAT/CD36 and CPT I in skeletal muscle increases proportionally with fat oxidation after endurance exercise training. 2006 to the paper
Santa Cruz Biotechnology polyclonal antibody against CPT I was used in immunoprecipitation to isolate CPT I from human skeletal muscle.
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
total:1
Comparison between human fetal and adult skin. 2010 to the paper
Sigma anti-chondroitin sulfate was used to perform immunohistochemistry in dilution 1:500 in order to show that dermal components express differentially between human fetal and adult skin and play important roles in fetal scarless healing.
CSGALNACT2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
CTSA
cathepsin A
total:3
Expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. 2007 to the paper
Rockland anti-human PPCA antibody was used in western blot to study the expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. more
CYB5A
cytochrome b5 type A
total:2
Cytochrome b5 expression in gonadectomy-induced adrenocortical neoplasms of the domestic ferret (Mustela putorius furo). 2008 to the paper
Santa Cruz Biotechnology rabbit anti-human cyt b5 antibody was used in immunohistochemistry at 1:200 dilution in order to demonstrate that that cyt b5 is upregulated during gonadectomy-induced adrenocortical neoplasia and is a marker of androgen synthetic potential in these tumors more
CYCS
cytochrome c, somatic
total:48
Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. 2010 to the paper
BD PharMingen anti-cytochrome c antibody was used to perform western blot in order to study the interaction between F1L and endogenous Bak. more
Cyp1A1
cytochrome P450 family 1 subfamily A member 1
total:15
Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer. 2009 to the paper
Chemicon International anti-CYP 1A1 antibody (AB1258) was used in western blot to determine the functional significance of aryl hydrocarbon receptor (AhR) in gastric carcinogenesis, and to explore the possible role of AhR in gastric cancer (GC) treatment more
CYP1A2
cytochrome P450 family 1 subfamily A member 2
total:2
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Alexis Biochemicals mouse anti-Mrp2 antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes. more
CYP1B1
cytochrome P450 family 1 subfamily B member 1
total:8
Preferential induction of cytochrome P450 1A1 over cytochrome P450 1B1 in human breast epithelial cells following exposure to quercetin. 2008 to the paper
Santa Cruz affinity purified goat polyclonal Cyp1B1 antibody was used in western blot in order to study the role of estrogen metabolism in estrogen-induced breast carcinogenesis more
CYP24A1
cytochrome P450 family 24 subfamily A member 1
total:1
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 to the paper
Santa Cruz anti-CYP24A1 (1:150) polyclonal antibody was used to perform immunocytochemistry in order to show that cathelicidin, a human antimicrobial peptide can be induced by vitamin D in the urinary bladder.
CYP27B1
cytochrome P450 family 27 subfamily B member 1
total:1
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 to the paper
Santa Cruz anti-CYP27B1 (D-20, 1:200) polyclonal antibody was used to perform immunocytochemistry in order to show that cathelicidin, a human antimicrobial peptide can be induced by vitamin D in the urinary bladder.
CYP2A13
cytochrome P450 family 2 subfamily A member 13
CYP2A6
cytochrome P450 family 2 subfamily A member 6
total:1
CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody. 2006 to the paper
BD Gentest anti-human CYP2A6 monoclonal antibody was used in western blotting and immunohistochemistry to study the role of CYP2A13 in human respiratory tissues and lung cancers.
CYP2A7
cytochrome P450 family 2 subfamily A member 7
CYP2C18
cytochrome P450 family 2 subfamily C member 18
CYP2C8
cytochrome P450 family 2 subfamily C member 8
total:3
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. 2009 to the paper
BD Biosciences-Pharmingen monoclonal anti-cytochrome c antibody was used in immunohistochemistry in order to introduce a rapid regulation of mitochondrial dynamics in acute kidney injury. more
CYP2C9
cytochrome P450 family 2 subfamily C member 9
total:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 to the paper
BD Gentest anti-CYP2C9 antibody (1:1000) was used in western blot in order to study the role of cardiomyocyte CPR and CPR-dependent enzymes in doxorubicin (Dox) mediated acute cardiotoxicity more
Cyp2e1
cytochrome P450 family 2 subfamily E member 1
total:7
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 to the paper
Oxford Biomedical Research anti-CYP2E1 antibody (1:1000) was used in western blot in order to study the role of cardiomyocyte CPR and CPR-dependent enzymes in doxorubicin (Dox) mediated acute cardiotoxicity more
CYP2F1
cytochrome P450 family 2 subfamily F member 1
CYP2R1
cytochrome P450 family 2 subfamily R member 1
CYP2S1
cytochrome P450 family 2 subfamily S member 1
CYP2W1
cytochrome P450 family 2 subfamily W member 1
CYP39A1
cytochrome P450 family 39 subfamily A member 1
CYP3A43
cytochrome P450 family 3 subfamily A member 43
CYP3A5
cytochrome P450 family 3 subfamily A member 5
total:1
Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil. 2005 to the paper
Dr. Stephen Leeder (Mercy Children's Hospital) CYP3A5-specific polyclonal antibody was used in western blot to study the inhibition of CYP3A4 and CYP3A5 by verapamil
CYP4A22
cytochrome P450 family 4 subfamily A member 22
CYP4F11
cytochrome P450 family 4 subfamily F member 11
total:1
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 to the paper
Proteintech polyclonal anti-CYP4F11 antibody was used to perform western blot in order to clarify that retinoic acid could inhibit CYP4F11 expression in human keratinocyte-derived HaCaT cells by multiple signaling pathways including RXR and JNK pathways.
CYP4F12
cytochrome P450 family 4 subfamily F member 12
CYP4F2
cytochrome P450 family 4 subfamily F member 2
CYP4F22
cytochrome P450 family 4 subfamily F member 22
CYP4F8
cytochrome P450 family 4 subfamily F member 8
CYP7B1
cytochrome P450 family 7 subfamily B member 1
CYP8B1
cytochrome P450 family 8 subfamily B member 1
cystathionine beta synthase
cystathionine beta-synthase
total:1
Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70. 2010 to the paper
ABNOVA mouse anti-CBS antibody was used for western blot in order to investigate the role of Hsp70 inducing agents in the treatment of genetic diseases.
CYTB
cytochrome b
cytochrome c
cytochrome c1
total:31
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR. 2006 to the paper
BD Pharmingen monoclonal anti-cytochrome c antibody was used in human HeLa cervical carcinoma cells and in western blot, immunoprecipitation to study the roles of TIA-1 and HuR in the translation of cytochrome c. more
DBT
dihydrolipoamide branched chain transacylase E2
total:1
Hepatitis C virus (HCV)-induced immunoglobulin hypermutation reduces the affinity and neutralizing activities of antibodies against HCV envelope protein. 2008 to the paper
Biodesign International anti-e2 antibody was used in ELISA in order to demonstrate that HCV infection of B cells induces hypermutation of immunoglobulin gene and inactivates neutralizing and CDC activity of antibodies produced by these cells
DDC
dopa decarboxylase
total:3
Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease. 2009 to the paper
Proteintech Group anti-DDC antibody was used for western blot analysis to study therapeutic effects of RPE cell transplantation in Parkinson's disease. more
DECR1
2,4-dienoyl-CoA reductase 1
total:1
Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development. 2007 to the paper
Invitrogen DecR1 antibody was used in western blot to study the role of DecR1 in mammary tumor development.
deoxycytidine kinase
total:3
Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity. 2009 to the paper
Abgent rabbit anti-DCK was used to perform western blot in order to show that resistance to cytarabine arabinoside is associated with population-specific genetic variants. more
DGAT1
diacylglycerol O-acyltransferase 1
total:1
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Santa Cruz anti-DGAT1 antibody was used in western blot, immunocytochemistry and immunoprecipitation to study the formation requirement of efficient hepatitis C virus particle.
DHCR24
24-dehydrocholesterol reductase
total:1
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate. 2008 to the paper
Proteintech Group Inc anti-Dhcr24 antibody was used for western blot in order to investigate the roles of elenium and isoflavones in the regulation of androgen-regulated gene expression in healthy rat dorsolateral prostate.
dihydrofolate reductase
total:1
Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment. 2005 to the paper
Research Genetics/Invitrogen rabbit anti-human DHFR polyclonal antibody was used in western blot to study the essential of identification of amino acids for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate treatment.
dihydropteridine reductase
quinoid dihydropteridine reductase
total:1
AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration. 2007 to the paper
Abcam mouse monoclonal DHPR antibody was used in western blot to study the role of novel dysferlin protein complex component AHNAK in skeletal muscle regeneration.
dihydropyrimidine dehydrogenase
total:2
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-DPYD was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
DNM2
dynamin 2
total:6
Mechanisms of Chlamydia trachomatis entry into nonphagocytic cells. 2007 to the paper
BD Biosciences anti-dynamin-2 antibody was used to carry out immunofluorescence assays in order to investigate the mechanism of entry for Chlamydia trachomatis into nonphagocytic cells. more
dopamine beta hydroxylase
dopamine beta-hydroxylase
total:4
Molecular mechanisms supporting a paracrine role of GABA in rat adrenal medullary cells. 2008 to the paper
Chemicon anti-chromogranin A antibody was used in immunocytochemistry in order to investigate the mechanism for the paracrine role of GABA in rat adrenal medullary (AM) cells at the molecular level. more
DSEL
dermatan sulfate epimerase like
ECHS1
enoyl-CoA hydratase, short chain 1
total:2
One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis. 2008 to the paper
Proteintech Group rabbit polyclonal anti-ECHS1 antibody was used for western blot in order to study the effect of altered proteome of morphologically normal colon crypts on familial adenomatous polyposis. more
ELOVL4
ELOVL fatty acid elongase 4
total:1
Haploinsufficiency is not the key mechanism of pathogenesis in a heterozygous Elovl4 knockout mouse model of STGD3 disease. 2006 to the paper
Abcam rabbit polyclonal anti-ELOVL4 antibody was used in western blot to characterize a mouse model with a targeted deletion of Elovl4 and to explore the role of this gene in retinal/macular degeneration.
ENO1
enolase 1
total:4
Evidence for an alternative glycolytic pathway in rapidly proliferating cells. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-N-terminus enolase antibody was used to carry out western blot analysis in order to clarify an alternative glycolytic pathway in many rapidly proliferating cells. more
eNOS
nitric oxide synthase 3
total:36
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. 2009 to the paper
Upstate Laboratories anti-eNOS antibody was used for western blot in order to investigate the role of purinergic in the regulation of endothelial nitric oxide synthase activity in endothelial cells. more
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit
total:3
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-XPD was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
ETFA
electron transfer flavoprotein subunit alpha
total:1
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 to the paper
ProteinTech Group anti-ETFA antibody was used to perform western blot in order to study the role of non-directed activity-based protein profiling plays in the identification of enzymes that are either predominantly or exclusively labeled in living cells.
ETFB
electron transfer flavoprotein subunit beta
ETHE1
ETHE1 persulfide dioxygenase
total:1
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
Neosystem anti-Ethe1 antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA.
FABP1
fatty acid binding protein 1
total:1
Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. 2010 to the paper
R&D Systems goat anti-human L-FABP polyclonal antibody was used to perform western blot in order to study the prognostic ability of urinary liver-type fatty acid-binding protein (L-FABP) in Acute kidney injury (AKI).
FABP4
fatty acid binding protein 4
total:2
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-A-FABP antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
CIAO2B
cytosolic iron-sulfur assembly component 2B
total:1
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Proteintech anti-Fam96B was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19.
fatty acid synthase
total:6
Fatty acid synthase expression in cutaneous melanocytic neoplasms. 2005 to the paper
Immuno-Biological Laboratories anti-fatty acid synthase antibody was used in immunohistochemistry to study expression of fatty acid synthase in cutaneous melanocytic neoplasms. more
FH
fumarate hydratase
total:1
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. 2005 to the paper
Quidel monoclonal anti-FH antibody was used in ELISA to study the association of the extracellular matrix and inflammation
FHL2
four and a half LIM domains 2
total:4
Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway. 2009 to the paper
Santa Cruz Biotechnology anti-FHL2 antibody was used for western blot to study the suppressing role of human FHL1 family members in the modulation of tumor cell growth through a TGF-beta like signaling pathway. more
FMO2
flavin containing dimethylaniline monoxygenase 2
frataxin
total:1
Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia. 2009 to the paper
Santa Cruz Biotechnology frataxin antibody was used in immunohistochemistry in order to suggest that the defective machinery for ISP synthesis affect the oxidative stress response in friedreich ataxia.
FTCD
formimidoyltransferase cyclodeaminase
total:2
Sonic hedgehog ligand partners with caveolin-1 for intracellular transport. 2009 to the paper
Abcam anti-FTCD antibody was used to carry out western blot analysis in order to elucidate the mechanism that regulates the intracellular transportation and secretion of Caveolin-1/Shh complex. more
G6PC3
glucose-6-phosphatase catalytic subunit 3
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GCLC
glutamate-cysteine ligase catalytic subunit
gephyrin
total:4
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-gephyrin antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
GGT2
gamma-glutamyltransferase 2
GK2
glycerol kinase 2
total:1
The Dickkopf-homolog 3 is expressed in tumor endothelial cells and supports capillary formation. 2008 to the paper
R&D systems mouse Dkk-3 monoclonal antibody was used to perform western blot in order to study the expression of Dkk-3 in various solid tumor types.
GLA
galactosidase alpha
total:2
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GLA polyclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease. more
GLB1
galactosidase beta 1
total:7
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. 2010 to the paper
Invitrogene anti-beta-Galactosidase antibody was used in immunocytochemistry for immunofluorescent staining to investigate the role of the NMDA receptors in the regulation of nicotine-conditioned place preference in dopamine neurons. more
GLP1R
glucagon like peptide 1 receptor
total:2
Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r). 2007 to the paper
Abcam GLP-1R antibody was used in western blot to study protein expression of GLP-1R to reveal tissue-specific strain differences in pancreas (congenic>B6) and stomach (B6>congenic). more
GLRX
glutaredoxin
total:2
S-glutathionylation impairs signal transducer and activator of transcription 3 activation and signaling. 2009 to the paper
AbFrontier anti-GRX-1 antibody was used to perform western blot in order to study the affect of the S-glutathionylation of STAT3. more
glucagon
total:13
Deletion of the mitochondrial flavoprotein apoptosis inducing factor (AIF) induces beta-cell apoptosis and impairs beta-cell mass. 2009 to the paper
Sigma anti-glucagon antibody was used to perform immunohistochemistry in order to study the role of mitochondrial flavoprotein apoptosis inducing factor. more
glucokinase
total:1
Spermatogenic cell-specific type 1 hexokinase is the predominant hexokinase in sperm. 2008 to the paper
ABGENT anti-GCK(N-term) polyclonal antibody was used to perform immunoblotting in order to study the role of spermatogenic cell-specific type 1 hexokinase(HK1S) in sperm.
glucose 6 phosphate dehydrogenase
glucose-6-phosphate dehydrogenase
total:7
Quiescent fibroblasts exhibit high metabolic activity. 2010 to the paper
Novus Biologicals anti-G6PD antibody was used to perform western blot in order to study the function of quiescent fibroblasts. more
glucuronyl C5 epimerase
glucuronic acid epimerase
total:1
Decreased expression of human D-glucuronyl C5-epimerase in breast cancer. 2008 to the paper
GenScript Corporation anti-GLCE antibody was used to perform western blot in order to study the GLCE expression in human breast cancer.
GLUT1
solute carrier family 2 member 1
total:23
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. 2009 to the paper
Abcam rabbit polyclonal anti-GLUT1 antibody was used to perform immunoblot in order to study the roles of the glucose deprivation during the development of KRAS pathway mutation. more
GLUT4
solute carrier family 2 member 4
total:11
ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization. 2009 to the paper
Millipore anti-Glut4 antibody was used to carry out western blot analysis in order to investigate the regulation of adipocyte glucose transport by ClipR-59 mediated Akt cellular compartmentalization. more
GLUT5
solute carrier family 2 member 5
total:2
Increased MCP-1 and microglia in various regions of the human alcoholic brain. 2008 to the paper
IBL anti-GluT5 antibody (1:400) was used to perform immunohistochemistry in order to study the MCP-1 expression and microglia activities in alcoholic brains. more
glutamine synthetase
glutamate-ammonia ligase
total:6
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Chemicon/Millipore murine anti-glutamine synthetase antibody was used in western blot in order to study the function of TMX3 in eye development. more
glyceraldehyde 3 phosphate dehydrogenase
glyceraldehyde-3-phosphate dehydrogenase
total:84
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Abcam anti-GAPDH antibody was used to perform western blot in order to study synaptic plasticity more
GNAI2
G protein subunit alpha i2
total:5
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
Abcam rabbit anti-GNAI2 antibody was used to carry out immunoprecipitation assays in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
GNAQ
G protein subunit alpha q
total:11
Caveolin-1 alters Ca(2+) signal duration through specific interaction with the G alpha q family of G proteins. 2008 to the paper
Santa Cruz rabbit anti-Galphaq antibody was used in immunocytochemistry to study the effect of the interaction between caveolin-1 and the Galphaq family of G proteins on Ca2+ signal duration. more
GNAS
GNAS complex locus
total:4
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 to the paper
United States Biological rabbit anti-GNAS antibody was used to carry out immunoprecipitation assays in order to investigate the role for the stereochemistry of beta2-adrenoceptor agonist fenoterol in determining receptor-G protein selectivity and downstream signaling. more
GNB5
G protein subunit beta 5
total:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 to the paper
Dr. W. Simonds (NINDK) rabbit anti-VAChT antibody was used in western blot to study the localization and differential interaction of R7 RGS proteins with R7BP and R9AP in neurons of vertebrate retina.
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
GPC3
glypican 3
total:1
Differential expression of syndecans and glypicans in chronically inflamed synovium. 2008 to the paper
Santa Cruz Biotechnologies anti-glypican-3 antibody was used in immunohistochemistry to investigate which HSPGs are expressed in knee joint synovia from patients with different forms of arthritis and normal individuals.
GPD1
glycerol-3-phosphate dehydrogenase 1
total:1
Central role of Gq in the hypertrophic signal transduction of angiotensin II in vascular smooth muscle cells. 2008 to the paper
Chemicon glyceraldehyde-3-phosphate dehydrogenase antibody was used in western blot in order to demonstrate that Gq coupling of the AT1 receptor is essential for the EGFR transactivation and subsequent VSMC hypertrophy induced by AngII
GPX1
glutathione peroxidase 1
total:3
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. 2009 to the paper
Affinity BioReagents ATP synthase antibody was used for western blot in order to investigate the role of mitochondria in endothelial cell dysfunction. more
GRIM 19
NADH:ubiquinone oxidoreductase subunit A13
total:2
Modulation of the caveolin-3 localization to caveolae and STAT3 to mitochondria by catecholamine-induced cardiac hypertrophy in H9c2 cardiomyoblasts. 2009 to the paper
BD Transduction Laboratories GRIM-19 antibody was used for western blot in order to investigate the roles of STAT3 and caveolin-3 in the regulation of the development of the catecholamine-induced cardiac hypertrophy. more
GST
glutathione S-transferase alpha 1
total:17
Expressions of glutathione S-transferase alpha, mu, and pi in brains of medically intractable epileptic patients. 2008 to the paper
Lab Vision Corporation anti-GSTA antibody was used to perform immunocytochemistry in order to show that the expression of glutathione S-transferase pi is at a higher level in the brains of medically intractable epileptic patients. more
GSTM1
glutathione S-transferase mu 1
total:2
Expressions of glutathione S-transferase alpha, mu, and pi in brains of medically intractable epileptic patients. 2008 to the paper
Lab Vision Corporation anti-GSTM antibody was used to perform immunocytochemistry in order to show that the expression of glutathione S-transferase pi is at a higher level in the brains of medically intractable epileptic patients. more
GSTP1
glutathione S-transferase pi 1
total:9
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4. 2009 to the paper
Sigma mouse GG-7 Fc-specific anti-human IgG antibody was used to confirm the presence of the Fc fragment of human IgG in order to illustrate that Toll-like receptor 4 (TLR4) plays a fundamental role in the sensing of LPS from Gram-negative bacteria. more
GSTT2
glutathione S-transferase theta 2 (gene/pseudogene)
GSTT2B
glutathione S-transferase theta 2B (gene/pseudogene)
GYS1
glycogen synthase 1
total:1
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Biosource glycogen synthase phosphorylated on Ser 641 and 645 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
HADH
hydroxyacyl-CoA dehydrogenase
total:1
COMMD1 expression is controlled by critical residues that determine XIAP binding. 2009 to the paper
Stressgen anti-SCHAD was used to perform immunoprecipitation in order to show that the expression of COMMD1 is regulated while COMMD1 and XIAP interact with each other via some critical residues
HADHA
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
HADHB
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
total:1
Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity. 2011 to the paper
Lifespan Biosciences anti-HADHB antibody was used to perform western blot in order to reveal how viperin facilitates the infectious process.
HAS1
hyaluronan synthase 1
total:1
Intronic splicing of hyaluronan synthase 1 (HAS1): a biologically relevant indicator of poor outcome in multiple myeloma. 2005 to the paper
Washington Biotechnology rabbit polyclonal anti-HAS1 antibody was used in western blot to study the intronic splicing of hyaluronan synthase 1 (HAS1).
HBA1
hemoglobin subunit alpha 1
total:2
Host biomarkers and biological pathways that are associated with the expression of experimental cerebral malaria in mice. 2008 to the paper
Novus Biologicals anti-hemoglobin alpha1 antibody was used in western blot to identify novel host molecules in the brain that are affected in the course of the pathological manifestation of CM. more
HDAC3
histone deacetylase 3
total:21
Histone deacetylase complexes promote trinucleotide repeat expansions. 2012 to the paper
Santa Cruz Biotechnology anti-HDAC3 antibody was used to perform western blot assay in order to identify novel histone deacetylase complexes that promote expansions of trinucleotide repeats. more
heparanase
total:6
Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. 2009 to the paper
Abgent anti-HPSE rabbit antibody (1:200) was used to perform western blot in order to study how to modulate gene expression and develop new drugs by short chain fatty acid (SCFA) hexosamine molecules. more
histidase
histidine ammonia-lyase
total:3
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Euromedex/IGBMC anti-His antibody (HIS-1G4) was used to perform western blot in order to study the role for TRAF4, a novel phosphoinositide-binding protein in modulating tight junctions and promoting cell migration. more
HK1
hexokinase 1
total:3
Spermatogenic cell-specific type 1 hexokinase is the predominant hexokinase in sperm. 2008 to the paper
Chemicon International anti-hexokinase type 1 polyclonal antibody was used to perform immunoblotting in order to study the role of spermatogenic cell-specific type 1 hexokinase(HK1S) in sperm. more
HK2
hexokinase 2
total:7
Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis. 2009 to the paper
Millipore HK2 antibody was used to perform western blot in order to investigate the relations between hexokinase 2 and prognosis of breast cancer more
HK3
hexokinase 3
total:1
Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis. 2009 to the paper
Abgent rabbit anti-Hexokinase 3 polyclonal antibody was used to perform western blot in order to investigate the relations between hexokinase 2 and prognosis of breast cancer
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
total:1
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-HMGCR antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism.
HO-1
heme oxygenase 1
total:10
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 to the paper
Stressgen anti-HO-1 antibody (1:500) was used in western blot in order to study the role of cardiomyocyte CPR and CPR-dependent enzymes in doxorubicin (Dox) mediated acute cardiotoxicity more
HO-2
heme oxygenase 2
total:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 to the paper
Stressgen anti-HO-2 antibody (1:5000) was used in western blot in order to study the role of cardiomyocyte CPR and CPR-dependent enzymes in doxorubicin (Dox) mediated acute cardiotoxicity more
holocarboxylase synthetase
total:1
Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. 2009 to the paper
Vector Laboratories primary anti-FLAG BioM2 antibody was used to do western blot analysis in order to study the preferential expression of the arylsulfatase I (ARSI) gene in retinal pigment epithelium cell line ARPE-19.
HPRT1
hypoxanthine phosphoribosyltransferase 1
total:1
The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 2009 to the paper
Abcam anti-HPRT antibody was used to perform western blot in order to study the role of Nedd4 plays in the biological process of muscle breakdown.
HPSE2
heparanase 2 (inactive)
total:1
Heparanase expression in circulating lymphocytes of breast cancer patients depends on the presence of the primary tumor and/or systemic metastasis. 2007 to the paper
Santa Cruz Biotechnology HPA2 antibody was used in immunocytochemistry (1:100) to demonstrate that heparanase was expressed in lymphocytes of breast cancer PBMC.
HS3ST1
heparan sulfate-glucosamine 3-sulfotransferase 1
HS3ST2
heparan sulfate-glucosamine 3-sulfotransferase 2
HS3ST3A1
heparan sulfate-glucosamine 3-sulfotransferase 3A1
HS3ST3B1
heparan sulfate-glucosamine 3-sulfotransferase 3B1
HS3ST4
heparan sulfate-glucosamine 3-sulfotransferase 4
HS3ST5
heparan sulfate-glucosamine 3-sulfotransferase 5
HS3ST6
heparan sulfate-glucosamine 3-sulfotransferase 6
HS6ST2
heparan sulfate 6-O-sulfotransferase 2
HSD11B1
hydroxysteroid 11-beta dehydrogenase 1
total:1
Quantitation and cellular localization of 11beta-HSD1 expression in murine thymus. 2006 to the paper
Dr. Zygmunt Krozowski (Baker Heart Research Institute) 11beta-HSD1 antibody was used in western blot to assess 11beta-HSD1 protein expression in whole tissues.
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSD3B7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
HSP90
heat shock protein 90 alpha family class A member 1
total:68
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-HSP90 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
IDH1
isocitrate dehydrogenase (NADP(+)) 1
total:1
Quiescent fibroblasts exhibit high metabolic activity. 2010 to the paper
Lifespan Biosciences anti-IDH1 antibody was used to perform western blot in order to study the function of quiescent fibroblasts.
IDH3A
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
total:1
Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders. 2009 to the paper
Abgent IDH3A antibody was used to perform western blot in order to investigate the relations between mitochondrial substrates and neurodegenerative diseases
IDH3B
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
IDH3G
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
IDI1
isopentenyl-diphosphate delta isomerase 1
total:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 to the paper
Protein Tech Group anti-IDI1 antibody was used to perform western blot in order to study the cytotoxicity of timosaponin AIII towards tumor cells.
IDI2
isopentenyl-diphosphate delta isomerase 2
IDO1
indoleamine 2,3-dioxygenase 1
total:1
T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response. 2010 to the paper
Chemicon International anti-IDO monoclonal antibody was used to perform immunohistochemistry in order to study the transcriptional features of T-cell/histiocyte-rich large B-cell lymphoma.
INPP4B
inositol polyphosphate-4-phosphatase type II B
INSIG1
insulin induced gene 1
total:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 to the paper
Biovision anti-INSIG-1 antibody was used to perform western blot in order to study the cytotoxicity of timosaponin AIII towards tumor cells.
insulin
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
IOP1
cytosolic iron-sulfur assembly component 3
total:1
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Sigma anti-NARFL/IOP1 was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19.
IQGAP1
IQ motif containing GTPase activating protein 1
total:6
The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1. 2006 to the paper
Santa Cruz Biotechnology polyclonal anti-IQGAP1 antibody was used in human A549 cells and in immunocytochemistry to study the interaction between the receptor protein-tyrosine phosphatase PTP and IQGAP1. more
ISCU
iron-sulfur cluster assembly enzyme
total:1
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Proteintech anti-ISCU was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19.
ITPA
inosine triphosphatase
total:1
Quantitative in vitro and in vivo characterization of the human P32T mutant ITPase. 2010 to the paper
Proteintech Group rabbit PolyAb anti-ITPA used to perform western blot in order to investigate the function of the human P32T ITPase
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
total:5
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 to the paper
Calbiochem IP3R1 antibody was used in western blot and immunohistochemistry to study the role of molecular alterations in the cerebellum of the PMCA2-null in Purkinje neurons. more
ITPR2
inositol 1,4,5-trisphosphate receptor type 2
total:2
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. 2005 to the paper
Santa Cruz Biotechnology goat anti-IP3R2 antibody was used in western blot to study the binding of phospholipid scramblase 1 to the promoter region of the inositol 1, 4, 5-triphosphate receptor type 1 more
KCNG2
potassium voltage-gated channel modifier subfamily G member 2
KCNS3
potassium voltage-gated channel modifier subfamily S member 3
ketohexokinase
total:2
Ketohexokinase: expression and localization of the principal fructose-metabolizing enzyme. 2009 to the paper
Abgent rabbit purified polyclonal KHK (C-terminal) antibody was used to perform immunohistochemistry in order to investigate the functions of ketohexokinase. more
KPNB1
karyopherin subunit beta 1
total:7
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-importin beta antibody (sc-137016) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
lactase
total:1
Stimulatory cross-talk between NFAT3 and estrogen receptor in breast cancer cells. 2005 to the paper
Stratagene anti-Lac polyclonal antibody was used in western blot to identify the transcription factor NFAT3 as a new ER-interacting partner in breast cancer cells.
LBR
lamin B receptor
total:10
Induction of a massive endoplasmic reticulum and perinuclear space expansion by expression of lamin B receptor mutants and the related sterol reductases TM7SF2 and DHCR7. 2010 to the paper
Epitomics rabbit monoclonal anti-LBR antibody was used in western blot and immunohistochemistry in order to investigate the effects of the expression of human LBR disease mutants on cellular structure. more
LCLAT1
lysocardiolipin acyltransferase 1
LDHA
lactate dehydrogenase A
total:9
Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR. 2010 to the paper
Chemicon International anti-LDH antibody was used for western blot in order to show that CP1 can activate TSC2 and repress mTOR. more
LDLR
low density lipoprotein receptor
total:10
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 to the paper
Santa Cruz anti-LDLr antibody was used in western blot in order to show that Wnt/catenin signaling, osteoblast function, and bone formation can be negatively regulated by the N-cadherin-axin-LRP5 interaction. more
LKB1
serine/threonine kinase 11
total:7
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. 2008 to the paper
Santa Cruz Biotechnology anti-Lkb1 antibody was used to perform western blot and immunohistochemistry in order to study the acinar polarity defects and cystic neoplasms induced by Lkb1-deficient in pancreas. more
LPGAT1
lysophosphatidylglycerol acyltransferase 1
LYS5
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
LYVE 1
lymphatic vessel endothelial hyaluronan receptor 1
total:7
Altered regulation of Prox1-gene-expression in liver tumors. 2008 to the paper
Reliatech rabbit polyclonal anti-Lyve-1 (1:500) antibody was used in immunohistochemistry to study Prox1-gene-expression in liver tumors more
MACS1
acyl-CoA synthetase medium chain family member 1
MARCKS
myristoylated alanine rich protein kinase C substrate
total:8
Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors. 2007 to the paper
Santa Cruz anti-MARCKS was used to perform western blot in order to show that in tumors the tranlation of some NMD-escape PTC-containing mRNAs could be repressed selectively. more
MBOAT1
membrane bound O-acyltransferase domain containing 1
MBOAT2
membrane bound O-acyltransferase domain containing 2
MBOAT7
membrane bound O-acyltransferase domain containing 7
MBTPS2
membrane bound transcription factor peptidase, site 2
MED1
mediator complex subunit 1
total:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-MED1 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
MINPP1
multiple inositol-polyphosphate phosphatase 1
MK2
MAPK activated protein kinase 2
total:18
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Cell Signaling Technology anti-MAPKAPK 2 (pT334) was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
MLRQ
NDUFA4 mitochondrial complex associated
MMS19
MMS19 homolog, cytosolic iron-sulfur assembly component
total:1
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Proteintech Group anti-MMS19 was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19.
mSin3A
SIN3 transcription regulator family member A
total:15
Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex. 2010 to the paper
Abcam anti-Sin3a trimethyl was used to perform western blot in order to study the role of deacetylase inhibitors to ING2 subunit from the Sin3 complex. more
MTHFD1
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
MTMR4
myotubularin related protein 4
total:1
The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 2009 to the paper
Abgent anti-MTMR4 antibody was used to perform western blot in order to study the role of Nedd4 plays in the biological process of muscle breakdown.
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
NCOA2
nuclear receptor coactivator 2
total:6
Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. 2006 to the paper
BD Biosciences mouse monoclonal anti-TIF2 antibody was used in western blot (1:500) and immunohistochemistry (1:500) to assess the consequences of reducing expression of the transcription intermediary factor 2 (TIF2) coactivator on prostate cancer cell growth. more
NCOA6
nuclear receptor coactivator 6
total:1
Characterization of activating signal cointegrator-2 as a novel transcriptional coactivator of the xenobiotic nuclear receptor constitutive androstane receptor. 2005 to the paper
anti-ASC-2 antibody was used in immunoprecipitation to study the characterization of activating signal cointegrator-2 as a novel transcriptional coactivator of the xenobiotic nuclear receptor constitutive androstane receptor.
NCoR
nuclear receptor corepressor 1
total:14
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-p300 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
ND1
NADH dehydrogenase, subunit 1 (complex I)
ND3
NADH dehydrogenase, subunit 3 (complex I)
ND4
NADH dehydrogenase, subunit 4 (complex I)
ND4L
NADH dehydrogenase, subunit 4L (complex I)
ND5
NADH dehydrogenase, subunit 5 (complex I)
ND6
NADH dehydrogenase, subunit 6 (complex I)
NDUFA9
NADH:ubiquinone oxidoreductase subunit A9
total:1
Targeting of the cytosolic poly(A) binding protein PABPC1 to mitochondria causes mitochondrial translation inhibition. 2010 to the paper
MitoSciences monoclonal against NDUFA9 was used to perform western blot in order to study the role of the cytosolic binding protein PABPC1 to mitochondria in mitochondrial translation.
NDUFB8
NADH:ubiquinone oxidoreductase subunit B8
total:1
Targeting of the cytosolic poly(A) binding protein PABPC1 to mitochondria causes mitochondrial translation inhibition. 2010 to the paper
MitoSciences monoclonal against NDUFB8 was used to perform western blot in order to study the role of the cytosolic binding protein PABPC1 to mitochondria in mitochondrial translation.
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
total:1
A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease. 2009 to the paper
Eugene anti-mitochondrial complex I 39 kDa subunit antibody was used for western blotting in order to demonstrate that in Parkinson's disease, a novel transferrin/TfR2-mediated mitochondrial iron transport system was disrupted
NDUFS4
NADH:ubiquinone oxidoreductase subunit S4
total:1
High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency. 2010 to the paper
Mitosciences anti-NDUFS4 antibody was used to perform western blot in order to study the role of the mutations in NUBPL and FOXRED1 in human complex I deficiency.
NDUFS8
NADH:ubiquinone oxidoreductase core subunit S8
NDUFV1
NADH:ubiquinone oxidoreductase core subunit V1
NDUFV2
NADH:ubiquinone oxidoreductase core subunit V2
NEU1
neuraminidase 1
total:1
Expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. 2007 to the paper
Rockland anti-human neuraminidase 1 antibody was used in western blot and immunoprecipitation to study the expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients.
NF-YA
nuclear transcription factor Y subunit alpha
total:13
Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-NF-YA antibody was used in immunoblot in order to study the role of tuberin and OGG1 in the pathogenesis of angiomyolipoma in TSC patients. more
NG2
chondroitin sulfate proteoglycan 4
total:12
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
Chemicon anti-NG2 antibody (1:1500) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation. more
NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1
nicotinamide N methyltransferase
nicotinamide N-methyltransferase
total:1
Nicotinamide N-methyltransferase upregulation inversely correlates with lymph node metastasis in oral squamous cell carcinoma. 2007 to the paper
Richard Weinshilboum rabbit polyclonal NNMT antibody was used in western blot at 1:1000 dilution and immunohistochemistry at 1:500 dilution to study the relationship between tumor characteristics and NNMT levels in OSCC.
NME1
NME/NM23 nucleoside diphosphate kinase 1
total:8
Evidence for an alternative glycolytic pathway in rapidly proliferating cells. 2010 to the paper
Abcam rabbit anti-nm23 antibody was used to carry out western blot analysis in order to clarify an alternative glycolytic pathway in many rapidly proliferating cells. more
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
NNT
nicotinamide nucleotide transhydrogenase
NPAS2
neuronal PAS domain protein 2
total:1
The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response. 2008 to the paper
Santa Cruz rabbit polyclonal anti-NPAS2 antibody was used to perform western blot in order to show that circadian gene NPAS2 is a putative tumor suppressor involved in DNA damage response.
NPC1L1
NPC1 like intracellular cholesterol transporter 1
NRF1
nuclear respiratory factor 1
total:1
Endurance exercise as a countermeasure for aging. 2008 to the paper
SantaCruz anti-NRF-1 antibody was used in western blot in order to investigate whether the mitochondrial dysfunction and reduced insulin sensitivity are inevitably caused by aging.
NSE
enolase 2
total:11
The diagnostic value of SYT-SSX detected by reverse transcriptase-polymerase chain reaction (RT-PCR) and fluorescence in situ hybridization (FISH) for synovial sarcoma: a review and prospective study of 255 cases. 2008 to the paper
Zymed Laboratory anti-NSE (G4) antibody was used to perform immunohistochemistry in order to study the diagnostic value of SYT-SSX detected by RT-PCR and FISH for synovial sarcoma. more
nucleoporin p62
nucleoporin 62
total:8
Fractionation of the Coxiella burnetii parasitophorous vacuole. 2008 to the paper
BD Biosciences mouse anti-human nuclear pore protein nucleoporin p62 antibody was used to perform western blot in order to develope a method to separate intact parasitophorous vacuole from host cell material. more
NUP133
nucleoporin 133
total:1
The nucleoporin Nup153 has separable roles in both early mitotic progression and the resolution of mitosis. 2009 to the paper
Covance anti-nucleoporin antibody was used to perform western blot in order to study the roles of Nup153 plays in mitosis.
NUP153
nucleoporin 153
total:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Abcam monoclonal anti-NUP was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
NUP88
nucleoporin 88
total:1
Caspases target only two architectural components within the core structure of the nuclear pore complex. 2006 to the paper
BD Biosciences monoclonal Nup88 antibody was used in western blot to identify caspase targets in the core structure of nuclear pore complex in Hela cells
OAZ2
ornithine decarboxylase antizyme 2
OCRL
OCRL inositol polyphosphate-5-phosphatase
ODC1
ornithine decarboxylase 1
total:2
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. 2010 to the paper
BIOMOL International anti-ODC antibody was used to carry out western blot analysis in order to investigate the precise contribution of 4E-BPs to mTORC1 signaling. more
p110
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
total:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-p110alpha was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
P17 3
NADH:ubiquinone oxidoreductase subunit B11
p53R2
ribonucleotide reductase regulatory TP53 inducible subunit M2B
p85
phosphoinositide-3-kinase regulatory subunit 1
total:43
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Upstate anti-p85 pAb was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
PA200
proteasome activator subunit 4
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal regulator PA200 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
PAICS
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
PAPSS1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
total:2
Oxysterols are substrates for cholesterol sulfotransferase. 2007 to the paper
Dr. Charles A. Strott (National Institute of Child Health and Human Development) PAPSS1 (1:2,000; HL4004) antibody was used in western blot to identify oxysterols as substrates for cholesterol sulfotransferase more
PAPST2
solute carrier family 35 member B3
PCCA
propionyl-CoA carboxylase subunit alpha
PCK2
phosphoenolpyruvate carboxykinase 2, mitochondrial
total:1
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 to the paper
Cayman Chemical PEPCK antibody was used for western blot in order to investigate the role of DBC1 in the regulation of SIRT1 activity and high-fat diet induced liver steatosis in mice.
PCYT1A
phosphate cytidylyltransferase 1, choline, alpha
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
total:1
Peripherally-derived BDNF promotes regeneration of ascending sensory neurons after spinal cord injury. 2008 to the paper
List Biological Labs CTB antibody was used in immunohistochemistry to study the role of BDNF in the regeneration of central axons of ascending sensory.
PCYT2
phosphate cytidylyltransferase 2, ethanolamine
PDHA1
pyruvate dehydrogenase E1 subunit alpha 1
total:2
Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma. 2009 to the paper
Invitrogen mouse monoclonal anti-PDH E1alpha was used to perform western blot in order to show that ROS production and PDK2 upregulation induced by mitochondrial ND2 mutation lead to HIF1alpha accumulation in head and neck squamous cell carcinoma. more
PDHB
pyruvate dehydrogenase E1 subunit beta
total:1
Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders. 2009 to the paper
Molecular Probes PDHB antibody was used to perform western blot in order to investigate the relations between mitochondrial substrates and neurodegenerative diseases
PDK1
pyruvate dehydrogenase kinase 1
total:9
Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. 2007 to the paper
Stressgen Bioreagents polyclonal anti-PDK1 antibody was used in western blot to study induction of vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1 by hypoxia-inducible factor 1 and dysregulated c-Myc more
PDK2
pyruvate dehydrogenase kinase 2
total:1
Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma. 2009 to the paper
Abgent rabbit polyclonal anti-PDK2 was used to perform western blot in order to show that ROS production and PDK2 upregulation induced by mitochondrial ND2 mutation lead to HIF1alpha accumulation in head and neck squamous cell carcinoma.
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
PDSS1
decaprenyl diphosphate synthase subunit 1
PDSS2
decaprenyl diphosphate synthase subunit 2
perlecan
heparan sulfate proteoglycan 2
total:5
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. 2006 to the paper
Chemicon monoclonal anti-perlecan antibody (MAB 1948) was used in frozen sections from mouse and in immunohistochemistry to study the identification of WARP as a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. more
PFAS
phosphoribosylformylglycinamidine synthase
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
total:1
Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases. 2009 to the paper
Abgent rabbit anti-PFKFB2 (number AP8146a) polyclonal antibody was used to perform western blot in order to demonstrate that overexpression of 6-phosphofructo-2-kinase (PFKFB3) in the nuclear increases cell proliferation via cyclin-dependent kinases.
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
total:2
Akt regulates the subcellular localization of the Rab27a-binding protein JFC1 by phosphorylation. 2005 to the paper
Santa Cruz Biotechnology phosphoglycerate kinase 1 antibody was used in western blot to study the role of akt in the subcellular localization of JFC1. more
PFKM
phosphofructokinase, muscle
total:3
Phosphofructokinase 1 glycosylation regulates cell growth and metabolism. 2012 to the paper
Santa Cruz Biotechnology anti-PFK1 was used at 1:1000 to perform western blot in order to show that cancer cell growth was regulated by PFK1 glycosylation more
PGAM1
phosphoglycerate mutase 1
total:1
Evidence for an alternative glycolytic pathway in rapidly proliferating cells. 2010 to the paper
Novus goat anti-PGAM1 antibody was used to carry out western blot analysis in order to clarify an alternative glycolytic pathway in many rapidly proliferating cells.
PGD
phosphogluconate dehydrogenase
total:2
Quiescent fibroblasts exhibit high metabolic activity. 2010 to the paper
GeneTex anti-PGD antibody (11,000 diluted in PBS-T/1% milk) was used to perform western blot in order to study the function of quiescent fibroblasts. more
PGIS
prostaglandin I2 synthase
total:4
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. 2005 to the paper
Oxford Biomedical Research mouse monoclonal PGIS antibody was used in western blot to demonstrate that the mPGES-1 enzyme is a primary release mechanism of PGH2 accumulation. more
PGK1
phosphoglycerate kinase 1
total:6
The DEAD-box protein Dhh1 promotes decapping by slowing ribosome movement. 2012 to the paper
Invitrogen anti-Pgk1 antibody was used to perform western blot to study the role of Dhh1 in the decapping and turnover of mRNA. more
PGS1
phosphatidylglycerophosphate synthase 1
PHKA1
phosphorylase kinase regulatory subunit alpha 1
PHKA2
phosphorylase kinase regulatory subunit alpha 2
PHKB
phosphorylase kinase regulatory subunit beta
PHKG1
phosphorylase kinase catalytic subunit gamma 1
PHOSPHO1
phosphoethanolamine/phosphocholine phosphatase 1
phospholipase C beta 4
total:2
A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients. 2005 to the paper
Dr Stefan Feske anti-PLCgamma antibody was used in western blot to study the defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients. more
phosphoserine phosphatase
total:2
Biochemical consequences of the NOS3 Glu298Asp variation in human endothelium: altered caveolar localization and impaired response to shear. 2007 to the paper
Upstate Biotechnology phosphoserine antibody was used in western blot to demonstrate functional consequences of the Glu298Asp NOS3 variation. more
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
P. de Camilli anti-PI4KII alpha antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
PI4KA
phosphatidylinositol 4-kinase alpha
total:1
Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol. 2010 to the paper
Proteintech group Inc anti-PI4KCA antibody was used to perform western blot in order to study the modulation of intracellular F. tularensis phagosome biogenesis and proliferation.
PIK3C3
phosphatidylinositol 3-kinase catalytic subunit type 3
total:3
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. 2009 to the paper
Abgent anti-PI3KC3 antibody was used in western blot in order to study the role of Beclin 1 in the regulation of autophagy. more
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
total:6
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz polyclonal anti-p110beta antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
total:5
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz anti-p110delta monoclonal antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
total:11
Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation. 2006 to the paper
Santa Cruz Biotechology anti-p110 gamma antibody was used in western blot in order to investigate the mechanism of the PI3K-IA (phosphatidylinositol 3-kinase Class IA) lipid kinase activity was affected by high NaCl and ionizing radiation. more
PIK3R2
phosphoinositide-3-kinase regulatory subunit 2
total:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Millipore polyclonal anti-human p85 antibody was used to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
PIK3R4
phosphoinositide-3-kinase regulatory subunit 4
total:1
Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. 2008 to the paper
Abgent rabbit anti-hVps15 antibody was used in western blot to identify the pathway and mechanism by which AAs signal to hVps34 to stimulate mTOR complex1 signaling.
PIK3R6
phosphoinositide-3-kinase regulatory subunit 6
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
total:1
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-PIP5K1alpha antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation.
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
total:1
Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl. 2009 to the paper
Abgent anti-PIP5KI antibody was used to perform western blot in order to study the role of wnt3a and dvl in phosphatidylinositol kinase regulation.
PKC alpha
protein kinase C alpha
total:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-PKCAalpha antibody was used in western blot in order to study the function of TMX3 in eye development. more
PKLR
pyruvate kinase L/R
total:1
Proteomic analysis of low dose arsenic and ionizing radiation exposure on keratinocytes. 2009 to the paper
Abcam anti-pyruvate kinase antibody was used to perform western blot in order to study the proteomic of the keratinocytes after the treatment of low dose arsenic and ionizing radiation exposure.
PKM
pyruvate kinase M1/2
total:4
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. 2011 to the paper
Abcam goat anti-PKM1/2 was used in 1:2000 to perform western blot in order to show that antioxidant responses could be achieved by pyruvate kinase M2 inactivation. more
PLA2G2A
phospholipase A2 group IIA
total:5
Effect of retinoic acid on gene expression in human conjunctival epithelium: secretory phospholipase A2 mediates retinoic acid induction of MUC16. 2005 to the paper
Upstate mouse monoclonal sPLA2 antibody was used in western blot to identify vitamin A-responsive genes in ocular surface epithelia. more
PLA2G4A
phospholipase A2 group IVA
total:8
Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport.. 2009 to the paper
Santa Cruz Biotechnology anit-cPLA2a antibody was used to perform western blot and immunocytochemistry to study the role of cPLA2a in the formation of intercisternal tubular continuities and transport through the Golgi complex. more
PLA2G4C
phospholipase A2 group IVC
total:1
OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity. 2009 to the paper
Invitrogen FLAG antibody was used to perform immunoprecipitation in order to investigate the relations between Dok-4 and T cell.
PLC-gamma1
phospholipase C gamma 1
total:32
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-PLCG1 antibody was used to carry out western blot analysis and immunoprecipitation assays in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
PLCB2
phospholipase C beta 2
total:3
Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. 2005 to the paper
Santa Cruz Biotechnology PLC beta2 antibody was used in western blot to study localization of TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells more
PLCD1
phospholipase C delta 1
total:6
Phospholipase C-delta1 modulates sustained contraction of rat mesenteric small arteries in response to noradrenaline, but not endothelin-1. 2008 to the paper
Upstate monoclonal anti-PLC-delta1 antibody diluted 1:200 was used in western blot in order to address the functional role of PLC-delta1 in smooth muscle contraction more
PLD2
phospholipase D2
total:1
Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway. 2005 to the paper
Novus Biologicals PLD2 antibody was used in immunoprecipitation to study ABCA1 phosphorylation and degradation
PLIN2
perilipin 2
total:2
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Santa Cruz anti-ADRP antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
PNPLA2
patatin like phospholipase domain containing 2
total:1
Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific. 2008 to the paper
Cayman Chemical polyclonal ATGL antibody was used in immunohistochemistry in order to study the expression pattern of ATGL in human skeletal muscle
PNPLA3
patatin like phospholipase domain containing 3
PNPLA8
patatin like phospholipase domain containing 8
POLD1
DNA polymerase delta 1, catalytic subunit
total:2
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Proteintech anti-POLD1 was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
POM121
POM121 transmembrane nucleoporin
PP1
protein phosphatase 1 catalytic subunit alpha
total:19
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. 2008 to the paper
Santa Cruz anti-PP1alpha was used to perform western blot in order to show that SRC-3/AIB1 coactivator function and turnover is regulated by essential phosphatases and a phospho-degron of SRC-3/AIB1 is primary determinants of its turnover. more
PP2AC
protein phosphatase 2 catalytic subunit alpha
total:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate monoclonal anti-PP2Ac antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
PLPP3
phospholipid phosphatase 3
total:2
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. 2007 to the paper
Sigma LPP-3 antibody was used in western blot to study the role of lipid phosphate phosphatase (LPP) 1 and sphingosine kinase1 (SphK1) in converting exogenous S1P to intracellular S1P. more
PLPP2
phospholipid phosphatase 2
total:1
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. 2007 to the paper
Sigma LPP-2 antibody was used in western blot to study the role of lipid phosphate phosphatase (LPP) 1 and sphingosine kinase1 (SphK1) in converting exogenous S1P to intracellular S1P.
PPAR
peroxisome proliferator activated receptor alpha
total:9
Integration of microRNA miR-122 in hepatic circadian gene expression. 2009 to the paper
Abcam rabbit polyclonal antibody PPAR was used for immunoprecipitation in order to study the circadian gene expression of integration of microRNA miR-122 in hepatic. more
PPCDC
phosphopantothenoylcysteine decarboxylase
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
PPP1CC
protein phosphatase 1 catalytic subunit gamma
total:2
Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma. 2007 to the paper
Santa Cruz Biotechnology goat polyclonal PP1 gamma C antibody was used in western blot to study the regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma more
PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha
total:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate polyclonal anti-PP2A-A antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
PPP2R1B
protein phosphatase 2 scaffold subunit Abeta
total:2
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. 2007 to the paper
Sigma-Aldrich polyclonal antibody to the PP2APR65 subunit was used to perform western blot in order to investigate the functions of salt-inducible kinase-1. more
PRELP
proline and arginine rich end leucine rich repeat protein
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
total:4
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
R&D technologies anti-PRKAA2 antibody was used to carry out western blot analysis and ChIP assays in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
PRKACA
protein kinase cAMP-activated catalytic subunit alpha
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
PRKACG
protein kinase cAMP-activated catalytic subunit gamma
total:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 to the paper
Santa Cruz Biotechnology anti-the catalytic D subunit of PKA antibody C-20 was used in human fibrosarcoma HT1080 cells and in western blot to study the role for tyrosine phosphorylation in full-scale activation of the eIF2alpha RNA-dependent protein kinase. more
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
total:9
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIalpha was used in immunohistochemistry to detect the PKA subunit RIalpha in human adrenal samples more
PRKAR2A
protein kinase cAMP-dependent type II regulatory subunit alpha
total:9
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Santa Cruz Biotechnology anti-PKA RII antibody was used in immunoprecipitation in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
PRKAR2B
protein kinase cAMP-dependent type II regulatory subunit beta
total:3
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIIbeta was used in immunohistochemistry to detect the PKA subunit RIIbeta in human adrenal samples more
PRKD1
protein kinase D1
total:15
Amino acid-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor are mediated by a phospholipase C/inositol 1,4,5-trisphosphate-independent pathway that requires G12, Rho, filamin-A, and the actin cytoskeleton. 2005 to the paper
Santa Cruz Biotechnology protein kinase C mu (C-20) antibody was used in western blot to study amino acid-stimulated Ca2+ oscillations through a phospholipase c/inositol 1, 4, 5-trisphosphate-independent pathway. more
prostaglandin E synthase
total:9
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Cayman Chemicals anti-mPGES-1 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
Protein disulfide-isomerase
prolyl 4-hydroxylase subunit beta
total:6
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 to the paper
Abcam anti-PDIA1 antibody was used to perform western blot in order to study the role of non-directed activity-based protein profiling plays in the identification of enzymes that are either predominantly or exclusively labeled in living cells. more
PRPS1
phosphoribosyl pyrophosphate synthetase 1
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1 like 1
PRPS2
phosphoribosyl pyrophosphate synthetase 2
PSMA1
proteasome 20S subunit alpha 1
total:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 to the paper
Abcam C2 proteasome antibody was used in western blot in order to demonstrate that increased AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathway more
PSMA3
proteasome 20S subunit alpha 3
total:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Santa Cruz Biotechnology anti-Psc3 antibody was used to carry out ChIP assays in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
PSMA4
proteasome 20S subunit alpha 4
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International mouse monoclonal anti-human 20S proteasome subunit alpha4 was used for immunohistochemistry to investigate the effect of immunoproteasome on the Multiple Sclerosis pathogenesis. more
PSMA7
proteasome 20S subunit alpha 7
total:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Enzo Life Sciences anti-alpha7 antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
PSMB1
proteasome 20S subunit beta 1
total:2
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta1 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD). more
PSMB5
proteasome 20S subunit beta 5
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta5 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
PSMB8
proteasome 20S subunit beta 8
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP7 antibody was used for immunohistochemistry to study the effect of immunoproteasome on the Multiple Sclerosis. more
PSMB9
proteasome 20S subunit beta 9
total:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP2 antibody was used to perform immunohistochemistry to study the role of immunoproteasome in the Multiple Sclerosis pathogenesis. more
PSMC4
proteasome 26S subunit, ATPase 4
total:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 to the paper
Cell Signaling Technology anti-phospho-Ser235/236-S6 antibody was used to perform immunocytochemistry in order to study the capacity of rapamycin to provide neuroprotection in Parkinson disease models. more
PSMC6
proteasome 26S subunit, ATPase 6
total:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 to the paper
New England BioLabs antiphospho-p44/42 MAPK antibody and p44/42 MAPK antibody (PhosphoPlus p44/42 MAPK antibody kit) was used in western blot to study the physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing RhoGEFs.
PSMD2
proteasome 26S subunit, non-ATPase 2
total:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S2 subunit antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication.
PSMD4
proteasome 26S subunit, non-ATPase 4
total:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S5a antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication. more
PSMD9
proteasome 26S subunit, non-ATPase 9
total:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p27 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
PSME1
proteasome activator subunit 1
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International rabbit polyclonal anti-PA28alpha antibody was used for immunohistochemistry to determine the role of immunoproteasome in the Multiple Sclerosis. more
PSME2
proteasome activator subunit 2
total:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 to the paper
BIOMOL anti-proteasome activator 28 subunit beta (PA28beta) antibodoy was used to perform western blot in order to confirm the effect on the expression of proteasome-interacting proteins caused by chronic ethanol feeding.
PSST
NADH:ubiquinone oxidoreductase core subunit S7
PTEN
phosphatase and tensin homolog
total:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Neomarkers PTEN antibody was used to perform immunohistochemistry in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
PTGDS
prostaglandin D2 synthase
total:2
Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid. 2007 to the paper
Osaka Bioscience Institute rabbit polyclonal anti-human L-PGDS (1:1,000 dilution) and anti-mouse L-PGDS (1:4,000 dilution) antibodies were used in immunohistochemistry to demonstrate lipocalin-type prostaglandin D synthase/beta-trace as a major amyloid beta-chaperone in human cerebrospinal fluid. more
PTGES3
prostaglandin E synthase 3
total:5
High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance. 2010 to the paper
Thermo Fisher anti-p23 antibody was used for performing immunoblotting and immunohistochemistry in order to study the effect of high levels of Hsp90 cochaperone p23 on tumor progression and prognosis in breast cancer. more
PTGS1
prostaglandin-endoperoxide synthase 1
total:12
Cyclooxygenase-2 is involved in the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma induced by tumor necrosis factor-alpha. 2009 to the paper
Santa Cruz anti-COX-1 antibody was used to perform western blot and immunohistochemistry in order to show that the cyclooxygenase-2 can leads to the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma. more
PTGS2
prostaglandin-endoperoxide synthase 2
total:54
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Santa Cruz Biotechnology anti-COX-2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
PTPMT1
protein tyrosine phosphatase mitochondrial 1
RAE1
ribonucleic acid export 1
total:1
The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response. 2008 to the paper
R&D Systems anti-RAE-1 antibody was used in flow cytometry in order to study the role of immune responses in the tumorigenicity of embryonic stem cells
Ran
RAN, member RAS oncogene family
total:17
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-RAN antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
RANBP2
RAN binding protein 2
total:4
Nitric oxide destabilizes Pias3 and regulates sumoylation. 2007 to the paper
Santa Cruz polyclonal anti-RanBP2 was used to perform western blot in order to show that global sumoylation and Pias3 stabilization could be regulated by nitric oxide. more
RAPGEF3
Rap guanine nucleotide exchange factor 3
total:3
Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels. 2007 to the paper
Santa Cruz Biotechnology anti-EPAC antibody was used in western blot to determine whether the PDE4 sequestered by DISC1 is released after cAMP elevation. more
RAPGEF4
Rap guanine nucleotide exchange factor 4
total:4
An autism-associated variant of Epac2 reveals a role for Ras/Epac2 signaling in controlling basal dendrite maintenance in mice. 2012 to the paper
Santa Cruz anti-Epac2 monoclonal antibody was used to perform coimmunoprecipitations in order to study the role of Epac2 coupleing with Ras signaling in controlling basal dendrite maintenance. more
RGL
ral guanine nucleotide dissociation stimulator like 1
RPS27A
ribosomal protein S27a
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
RRM1
ribonucleotide reductase catalytic subunit M1
total:2
An association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients. 2007 to the paper
Chemicon International mouse monoclonal anti-RRM1 (1:500) antibody was used in western blot to study the association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients more
RTEL1
regulator of telomere elongation helicase 1
total:1
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-RTEL1 was used to perform western blot and immunoprecipitation in order to show that DNA metabolism and genomic integrity were maintained by MMS19.
RXRalpha
retinoid X receptor alpha
total:14
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 to the paper
Santa Cruz Biotechnology polyclonal RXRs antibody was used to perform western blot in order to clarify that retinoic acid could inhibit CYP4F11 expression in human keratinocyte-derived HaCaT cells by multiple signaling pathways including RXR and JNK pathways. more
SACM1L
SAC1 like phosphatidylinositide phosphatase
SAR1B
secretion associated Ras related GTPase 1B
SDC2
syndecan 2
total:2
Syndecan-4 is required for thrombin-induced migration and proliferation in human vascular smooth muscle cells. 2005 to the paper
Seikagaku HSPG neo-epitope (exposed after heparitinase III digestion, clone 3G10) antibody was used in western blot to study thrombin-induced human vascular smooth muscle cell migration and proliferation more
SDC3
syndecan 3
total:1
Prolonged labour associated with lower expression of syndecan 3 and connexin 43 in human uterine tissue. 2006 to the paper
Zymed Laboratories rabbit anti syndecan-3 antibody was used in immunohistochemistry to study its expression in human uterine tissue during prolonged labour
SDC4
syndecan 4
total:3
Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans. 2008 to the paper
Santa Cruz Biotechnology anti-syndecan-4 antibody was used in immunocytochemistry to study the effect of heparanase on cell adhesion and spreading. more
SDHA
succinate dehydrogenase complex flavoprotein subunit A
SDHB
succinate dehydrogenase complex iron sulfur subunit B
total:3
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
Invitrogen anti-SDH antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA. more
SDHC
succinate dehydrogenase complex subunit C
SDHD
succinate dehydrogenase complex subunit D
SEC23A
Sec23 homolog A, COPII coat complex component
total:3
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents Sec23 antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
SEC24A
SEC24 homolog A, COPII coat complex component
SEC24B
SEC24 homolog B, COPII coat complex component
SEC24C
SEC24 homolog C, COPII coat complex component
SEC24D
SEC24 homolog D, COPII coat complex component
SGLT4
solute carrier family 5 member 9
SGPP1
sphingosine-1-phosphate phosphatase 1
SHIP
inositol polyphosphate-5-phosphatase D
total:11
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 to the paper
Santa Cruz mouse anti-SHIP1 was used to perform western blot in order to show that IRAK-1 blockade is important for tolerance of human DCs induced by TLR2 and TLR4 stimulation. more
SHIP2
inositol polyphosphate phosphatase like 1
SLC19A2
solute carrier family 19 member 2
total:2
TRE-dependent transcription activation by JDP2-CHOP10 association. 2008 to the paper
Santa Cruz THTR1 polyclonal antibody was used in ChIP assays in order to identify CHOP10 as a novel protein associating protein for JDP2 more
SLC19A3
solute carrier family 19 member 3
total:1
Differentiation-dependent up-regulation of intestinal thiamin uptake: cellular and molecular mechanisms. 2005 to the paper
Sigma-Genosys polyclonal anti-hTHTR-2 antibody was used in western blot to study the association of intestinal thiamin uptake with differentiation.
SLC22A1
solute carrier family 22 member 1
total:3
A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress. 2009 to the paper
Upstate anti-Oct1 antibody was used to perform EMSA in order to study the mechanism of transcription regulation performed by Oct1 and Oct4 under genotoxic and oxidative stress. more
SLC25A10
solute carrier family 25 member 10
total:4
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
Sigma-Aldrich mouse anti-DIC antibody was used in western blot (1:1,000) and immunocytochemistry (1:200) in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation. more
SLC25A4
solute carrier family 25 member 4
total:3
Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-ANT antibody was used for western blot in order to investigate the role of Ischaemic preconditioning in the regulation of proteasomal activity and the degradation of PKCdelta during reperfusion. more
SLC25A5
solute carrier family 25 member 5
total:1
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase. 2007 to the paper
Dr. Douglas C. Wallace (University of California, Irvine) ANT2-specific antiserum was used in western blot to study the regulation of insulin secretion by SIRT4
SLC2A3
solute carrier family 2 member 3
total:2
Essential role of glucose transporter GLUT3 for post-implantation embryonic development. 2009 to the paper
Santa Cruz Biotechnology Goat anti-GLUT3 antibody was used in immunostaining of blastocysts in order to indicate that GLUT3 is important in early embryonic development. more
SLC5A1
solute carrier family 5 member 1
total:2
Involvement of an enterocyte renin-angiotensin system in the local control of SGLT1-dependent glucose uptake across the rat small intestinal brush border membrane. 2007 to the paper
Abcam anti-SGLT1 rabbit polyclonal antibody (1 : 600) was used in western blot to assesse the effects of AII on SGLT1-dependent glucose transport across the brush border membrane (BBM). more
SLC5A4
solute carrier family 5 member 4
SLC5A6
solute carrier family 5 member 6
SLCO1A2
solute carrier organic anion transporter family member 1A2
total:1
The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3. 2007 to the paper
Dr. D. Keppler (German Cancer Research Center) human OATP1B1 antibody was used in western blot to investigate the potential role of macrolides on macrolide-induced drug interactions.
SLCO1B1
solute carrier organic anion transporter family member 1B1
total:1
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Dr.Bruno Stieger rabbit anti-Oatp2 antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes.
SLCO1B3
solute carrier organic anion transporter family member 1B3
total:1
The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3. 2007 to the paper
Dr. D. Keppler (German Cancer Research Center) human OATP1B3 antibody was used in western blot to investigate the potential role of macrolides on macrolide-induced drug interactions.
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMRT
nuclear receptor corepressor 2
total:11
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Affinity Bioreagents anti-SMRT antibody was used to perform western blot in order to show that IRF5 mediates the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
SNAP
synaptosome associated protein 25
total:11
Fast vesicle fusion in living cells requires at least three SNARE complexes. 2010 to the paper
Synaptic Systems polyclonal anti-SNAP-25 antibody was used to carry out western blot analysis in order to investigate how many SNARE complexes are required for exocytosis fusion. more
Sp1
Sp1 transcription factor
total:70
Sp1 and KLF15 regulate basal transcription of the human LRP5 gene. 2010 to the paper
Santa Cruz anti-Sp1 antibody was used to perform ChIP assay in order to study the regulatory function of Sp1 and KLF15 on basal transcription of the human LRP5 gene. more
SPHK1
sphingosine kinase 1
total:1
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. 2007 to the paper
Oncogene Research Products SphK1 antibody was used in western blot to study the role of lipid phosphate phosphatase (LPP) 1 and sphingosine kinase1 (SphK1) in converting exogenous S1P to intracellular S1P.
SPHK2
sphingosine kinase 2
total:1
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. 2007 to the paper
Oncogene Research Products SphK2 antibody was used in western blot to study the role of lipid phosphate phosphatase (LPP) 1 and sphingosine kinase1 (SphK1) in converting exogenous S1P to intracellular S1P.
SPTLC1
serine palmitoyltransferase long chain base subunit 1
total:3
Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology. 2009 to the paper
Abnova rabbit anti-SPT1 antibody was used to perform western blot in order to study the cellular localization of SPT1 and its functions in cell morphology. more
SPTLC2
serine palmitoyltransferase long chain base subunit 2
total:1
SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter. 2008 to the paper
Abgent anti-SPTLC2 antibody was used to perform western blot in order to study the interaction of ABCA1 and SPTLC1.
SPTLC3
serine palmitoyltransferase long chain base subunit 3
SR-BI
scavenger receptor class B member 1
total:11
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Novus rabbit polyclonal anti-SR-B1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
SRC-1
nuclear receptor coactivator 1
total:12
The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors. 2009 to the paper
Affinity BioReagents anti-SRC1 antibody was used in immunoprecipitation in order to investigate the cooperation between thyroid hormone receptor beta2 and p160 coactivator PAS-B through multiple contact surfaces. more
SREBF2
sterol regulatory element binding transcription factor 2
total:3
Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. 2005 to the paper
Santa Cruz Biotechnology anti-SREBP2 antibody was used in western blot to study the effect of liver X receptor alpha on SREBP1c-mediated Abcd2 expression more
SREBP cleavage activating protein
SREBF chaperone
total:1
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-SCAP antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism.
SREBP-1
sterol regulatory element binding transcription factor 1
total:11
Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. 2009 to the paper
NeoMarkers monoclonal SREBP-1 antibody was used in western blot in order to study the mechanism by which the activation of Wnt/beta-catenin signaling in skeletal muscle cells can improve insulin sensitivity. more
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STARD4
StAR related lipid transfer domain containing 4
STARD5
StAR related lipid transfer domain containing 5
STARD6
StAR related lipid transfer domain containing 6
SUCLA2
succinate-CoA ligase ADP-forming subunit beta
total:1
A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease. 2009 to the paper
Biogenex anti-human mitochondrial antigen antibody was used for immunohistochemistry in order to demonstrate that in Parkinson's disease, a novel transferrin/TfR2-mediated mitochondrial iron transport system was disrupted
SUCLG1
succinate-CoA ligase GDP/ADP-forming subunit alpha
SUCLG2
succinate-CoA ligase GDP-forming subunit beta
total:1
A proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells. 2009 to the paper
Santa Cruz Biotechnology G-Beta antibody was used to do immune precipitation in order to study a proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells.
SULT1E1
sulfotransferase family 1E member 1
total:5
Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver. 2006 to the paper
Pan-Vera polyclonal rabbit anti-human SULT1E1 antibody was used in western blot to study the different expression pattern of hepatic SULT1A1, SULT1E1, and SULT2A1. more
SULT2A1
sulfotransferase family 2A member 1
total:2
Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver. 2006 to the paper
Pan-Vera polyclonal rabbit anti-human SULT2A1 antibody was used in western blot to study the different expression pattern of hepatic SULT1A1, SULT1E1, and SULT2A1. more
SULT2B1
sulfotransferase family 2B member 1
total:1
Oxysterols are substrates for cholesterol sulfotransferase. 2007 to the paper
Dr. Charles A. Strott (National Institute of Child Health and Human Development) SULT2B1b (1:2,000; HL4360 #9) antibody was used in western blot to identify oxysterols as substrates for cholesterol sulfotransferase
syndecan
syndecan 1
total:26
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 to the paper
Cell Sciences B-A38 (Syndecan-1) antibody was used in western blot in order to demonstrate that heparanase can promote expression of syndecan-1 in the nucleus. more
syntaxin
syntaxin 1A
total:11
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-syntaxin-1 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
TBXAS1
thromboxane A synthase 1
total:3
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. 2009 to the paper
Abcam anti-TBXAS1 antibody was used to perform western blot in order to study the novel BRAF fusion gene in 7q34 duplication of pediatric low-grade astrocytomas detected by high density SNP-based genotype array analysis. more
TECRL
trans-2,3-enoyl-CoA reductase like
TGS1
trimethylguanosine synthase 1
total:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Mercury mouse anti-2, 2, 7-trimethylguanosine (TMG)antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing.
thioredoxin
total:15
TXNL6 is a novel oxidative stress-induced reducing system for methionine sulfoxide reductase a repair of α-crystallin and cytochrome C in the eye lens. 2010 to the paper
Abcam Trx 1 antibody (1:1000) was used to perform western blot and immunocytochemistry in order to clarify a critical role for TXNL6 in MsrA repair of essential lens proteins under oxidative stress conditions and that TXNL6 is important for MsrA defense protection against cataract. more
TM7SF2
transmembrane 7 superfamily member 2
TPH1
tryptophan hydroxylase 1
total:2
Regional, cellular, and subcellular localization of RGS10 in rodent brain. 2005 to the paper
Sigma tryptophan hydroxylase antibody was used in immunohistochemistry to elucidate RGS10 function in the nervous system. more
TPI1
triosephosphate isomerase 1
total:1
Protein expression profiling in the spectrum of renal cell carcinomas. 2010 to the paper
Proteintech rabbit anti-TPI-1 antibody(1 ug/ml) was used to perform immunostaining in order to study the differentiation in renal cell carcinomas(RCC) followed by specific protein expression.
TPMT
thiopurine S-methyltransferase
total:1
Thiopurine S-methyltransferase pharmacogenetics: autophagy as a mechanism for variant allozyme degradation. 2008 to the paper
Abgent anti-TPMT was used to perform western blot in order to show that autophagy is one of the mechanisms responsible for allozyme thiopurine S-methyltransferase (TPMT) *3A degradation.
TPR
translocated promoter region, nuclear basket protein
TPTE
transmembrane phosphatase with tensin homology
TPTE2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
TRB3
tribbles pseudokinase 3
total:2
Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis. 2008 to the paper
EMD Chemicals anti-TRB3 antibody was used to perform western blot in order to study the response of the mTORC1 signaling after the inhibition of protein synthesis. more
TXNRD1
thioredoxin reductase 1
total:2
Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities. 2009 to the paper
Santa Cruz Biotechnology anti-TrxR1 antibody was used in western blot in order to show that adiponectin haploinsufficiency can promote mammary tumorigenesis through inhibition of PTEN activity and activation of PI3K/Akt signalling pathway. more
tyrosine hydroxylase
total:25
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Abcam anti-Tyrosine Hydroxylase antibody (ab6211) was used to perform immunohistochemistry in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
UBC
ubiquitin C
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
ubiquitin
ubiquitin B
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
UCP3
uncoupling protein 3
total:1
UCP-2 and UCP-3 proteins are differentially regulated in pancreatic beta-cells. 2008 to the paper
Chemicon rabbit anti-UCP-3 antibody (AB-3046) was used in western blot and immunohistochemistry to study the distinct roles for UCP-2 and UCP-3 in regulating beta-cell function.
UGCG
UDP-glucose ceramide glucosyltransferase
UGT1A1
UDP glucuronosyltransferase family 1 member A1
total:2
Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene. 2008 to the paper
Gentest anti-UGT1A antibody (1:500) was used in western blot to identify UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene. more
UGT1A3
UDP glucuronosyltransferase family 1 member A3
UGT1A4
UDP glucuronosyltransferase family 1 member A4
total:1
Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4. 2007 to the paper
BD Gentest anti-UGT1A antibody (diluted 1:1500) was used in western blot to study the roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4.
UGT1A5
UDP glucuronosyltransferase family 1 member A5
UGT1A6
UDP glucuronosyltransferase family 1 member A6
UGT1A7
UDP glucuronosyltransferase family 1 member A7
UGT1A8
UDP glucuronosyltransferase family 1 member A8
UGT2A1
UDP glucuronosyltransferase family 2 member A1 complex locus
UGT2B10
UDP glucuronosyltransferase family 2 member B10
UGT2B11
UDP glucuronosyltransferase family 2 member B11
UGT2B15
UDP glucuronosyltransferase family 2 member B15
UGT2B17
UDP glucuronosyltransferase family 2 member B17
UGT2B28
UDP glucuronosyltransferase family 2 member B28
UGT2B4
UDP glucuronosyltransferase family 2 member B4
UGT2B7
UDP glucuronosyltransferase family 2 member B7
uncoupling protein 2
total:3
Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production. 2005 to the paper
Santa Cruz Biotechnology Ucp2 antibody was used in western blot to study the molecular mechanisms in enhancing the resistance to infectious microorganisms by disrupting the uncoupling protein-2 gene. more
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
UQCR11
ubiquinol-cytochrome c reductase, complex III subunit XI
UQCRB
ubiquinol-cytochrome c reductase binding protein
UQCRC1
ubiquinol-cytochrome c reductase core protein 1
UQCRC2
ubiquinol-cytochrome c reductase core protein 2
total:1
Targeting of the cytosolic poly(A) binding protein PABPC1 to mitochondria causes mitochondrial translation inhibition. 2010 to the paper
MitoSciences monoclonal against core 2 complex III was used to perform western blot in order to study the role of the cytosolic binding protein PABPC1 to mitochondria in mitochondrial translation.
UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
total:1
Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding. 2006 to the paper
BD Biosciences monoclonal anti-RIP1 antibody was used in western blot and immunoprecipitation to study the role for the binding of Triad3A with Hsp90 in regulating ubiquitination and proteasomal degradation of RIP1 in human embryonic kidney 293 cells.
UQCRH
ubiquinol-cytochrome c reductase hinge protein
VAMP2
vesicle associated membrane protein 2
total:8
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-synaptobrevin-2 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
VCAN
versican
total:4
Expression of ZIC family genes in meningiomas and other brain tumors. 2010 to the paper
Sigma-Aldrich anti-chondroitin sulfate proteoglycan antibody was used to perform immunohistochemistry in order to investigate the expression profiles of ZIC genes in brain tumors. more
visfatin
nicotinamide phosphoribosyltransferase
total:1
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 to the paper
Bethyl Laboratories NAMPT antibody was used for western blot in order to investigate the role of DBC1 in the regulation of SIRT1 activity and high-fat diet induced liver steatosis in mice.
vitamin D binding protein
GC vitamin D binding protein
total:3
An intronic locus control region plays an essential role in the establishment of an autonomous hepatic chromatin domain for the human vitamin D-binding protein gene. 2007 to the paper
Cocalico Biologicals rabbit polyclonal anti-hDBP antibody was used in radial immunodiffusion (RID) assay to study the role of an intronic locus control region in the establishment of an autonomous hepatic chromatin domain for the human vitamin D-binding protein gene. more
WASL
WASP like actin nucleation promoting factor
total:2
The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal Cdc42 antibody was used in western blot and immunoprecipitation to study the role of the adapter protein CrkII in the regulation of N-WASp and Cdc42 activation. more
ZDHHC21
zinc finger DHHC-type palmitoyltransferase 21