Metabolism of proteins
gene
reagent
sample publication
sample review
total:38
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. 2011 to the paper
Cell Signaling Technology anti-4E-BP1 and phospho-T37/T46 4E-BP1, phospho-S65 4E-BP1 were used to perform western blot in order to show that how growth factor signaling is inhibited by mTOR through mTOR-regulated phosphoproteome. more
total:8
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Santa Cruz anti-ACE was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:5
Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-XL protein. 2007 to the paper
Molecular Probes anti-pyruvate dehydrogenase antibody was used to perform western blot in order to study the interaction between SARS-CoV with Bcl-XL to result in cell apoptosis. more
total:1
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. 2009 to the paper
ABGEN aconitase-2 antibody was used for western blot in order to investigate the role of mitochondria in endothelial cell dysfunction.
total:8
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Abcam ACTH antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
total:2
Vascular endothelial growth factor upregulates expression of ADAMTS1 in endothelial cells through protein kinase C signaling. 2006 to the paper
Sigma Chemical abbit polyclonal C-terminal of human anti ADAMTS1 antibody was used in western blot to study the regulation of ADAMTS1 expression in endothelial cells by vascular endothelial growth factor (VEGF). more
total:1
Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion. 2008 to the paper
Santa Cruz Biotechnology TTP antibody was used in immunocytochemistry in order to study the mechanism of persistent translation arrest
total:1
The regulation of aggrecanase ADAMTS-4 expression in human Achilles tendon and tendon-derived cells. 2008 to the paper
Serotec ADAMTS-4 were used in western blot in order to study the effects of growth factors on the regulation of ADAMTS-4 expression
total:6
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 to the paper
IgG corporation rabbit polyclonal anti-ang II serum was used in immunohistochemistry in order to study the glomerular AGT's expression and its correlation with expression of other RAS components more
total:1
p125 is localized in endoplasmic reticulum exit sites and involved in their organization. 2005 to the paper
Chemicon International polyclonal anti-mannosidase II antibody was used in immunocytochemistry to study the localiation and function of p125 in endoplasmic reticulum.
total:19
Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2. 2009 to the paper
GeneTex mouse anti-tubulin antibody was used in western blot to study the role for the binding and interaction of ferroportin with Jak2 in hepcidin-induced internalization of ferroportin. more
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
V. Faundez anti-mu 3-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
total:7
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. 2008 to the paper
Calbiochem anti-ATF3(c-19) antibody was used to perform western blot in order to study the important role of CD30 signaling in Hodgkin's and anaplastic large cell lymphoma (ALCL) cell lines. more
total:11
Pharmacological brake-release of mRNA translation enhances cognitive memory. 2013 to the paper
Santa Cruz Biotechnologies anti-CREB-2 antibody was used to perform western blot in order to investigate the molecular mechanism of memory consolidation. more
total:3
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD. 2008 to the paper
Santa Cruz Biotechnologies anti-F1-ATPase was used to perform western blot in order to demonstrate that OS-9 and XTP3-B/erlectin are ER-resident glycoproteins that bind to ERAD substrates and, via the SEL1L adaptor, to the ER membrane-embedded ubiquitin ligase Hrd1. more
total:2
MCU encodes the pore conducting mitochondrial calcium currents. 2013 to the paper
Abcam anti-ATP5B antibody was used to perform western blot in order to investigate the functional property of the MCU gene. more
total:1
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 to the paper
Abcam anti-ATP6V0D1 was used to perform western blot in order to show that vacuolar H+-ATPase is involved in mTOR pathway for mTORC1 translocation and activation.
total:1
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
Invitrogen anti-Core1 antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA.
total:1
Sds22, a PP1 phosphatase regulatory subunit, regulates epithelial cell polarity and shape [Sds22 in epithelial morphology]. 2009 to the paper
Cappel rabbit anti-betaGal antibody (1:100) was used in immunocytochemistry in order to investigate the role of Sds22 in the regulation of epithelial cell polarity and shape.
total:1
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
ProteinTech Group anti-BCS1L antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA.
total:149
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-beta-actin was used to perform western blot in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
total:25
Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier. 2010 to the paper
Chemicon International mouse anti-beta tubulin antibody was used to carry out western blot analysis in order to investigate elastin-like polypeptide as carrier to target cell cycle inhibitory peptide for inhibiting ovarian cancer cell proliferation. more
total:1
Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma. 2007 to the paper
Dr. Martha Vaughan (National Heart, Lung, and Blood Institute) BIG1 antibody was used in western blot, immunoprecipitation and immunocytochemistry to study the regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma
total:47
RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. 2013 to the paper
Abcam GRP78/BiP rabbit polyclonal (1:25) was used to perform the immunoblotting to study the translation of a subset of mRNAs encoding secretory proteins potentiated by RanBP2/Nup358. more
total:6
Identification and characterization of ovarian cancer-initiating cells from primary human tumors. 2008 to the paper
Santa Cruz Biotechnology monoclonal anti-cancer antigen-125 (CA-125) antibody was used in immunocytochemistry to identify and characterize a self-renewing subpopulation of human ovarian tumor cells. more
total:75
A Bacteriophage tailspike domain promotes self-cleavage of a human membrane-bound transcription factor, the myelin regulatory factor MYRF. 2013 to the paper
Santa Cruz Biotechnology rabbit anti-calnexin and goat anti-calnexin antibodies were used to perform western blot and immunocytochemistry in order to investigate the mechanism of self-cleavage of MYRF. more
total:39
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Stressgen anti-calreticulin antibody was used in western blot and immunocytochemistry to study the formation requirement of efficient hepatitis C virus particle. more
total:13
Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. 2009 to the paper
Santa Cruz Biotechnology primary anti-cathepsin D (H-75) was used to detect endogenous lysosomal and ER proteins by immunohistochemistry method in order to study the preferentially expressed characterization of the arylsulfatase I (ARSI) gene. more
total:1
Modulation of STAT3 folding and function by TRiC/CCT chaperonin. 2014 to the paper
Abcam anti-CCT2 was used to perform western blotting to study that TRiC/CCT regulates STAT3 function.
total:2
Modulation of STAT3 folding and function by TRiC/CCT chaperonin. 2014 to the paper
Abcam anti-CCT5 was used to perform western blotting to study that TRiC/CCT regulates STAT3 function. more
total:1
Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells. 2006 to the paper
Santa Cruz Biotechnology TCP-{eta} antibody was used in western blot to study its expression regulation in human myelomonocytic THP-1 cell lysate in response to NOD2 receptor activation by muramyl dipeptide
total:22
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD10 was used in 3ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:14
Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. 2009 to the paper
Santa Cruz anti-aminopeptidase N antibody was used in immunohistochemistry in order to investigate the role of neprilysin in the regulation of pulmonary vascular remodeling in response to chronic hypoxia. more
total:1
Development of sandwich-type ELISAs for the quantification of rat and murine thrombin activatable fibrinolysis inhibitor in plasma. 2008 to the paper
A. GILS (Katholieke Universiteit Leuven) TAFI antibody was used in elisa to develope an ELISA for the quantification of rat and murine TAFI in plasma.
total:1
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Transduction Laboratories CPE antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion
total:3
Expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. 2007 to the paper
Rockland anti-human PPCA antibody was used in western blot to study the expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. more
total:31
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR. 2006 to the paper
BD Pharmingen monoclonal anti-cytochrome c antibody was used in human HeLa cervical carcinoma cells and in western blot, immunoprecipitation to study the roles of TIA-1 and HuR in the translation of cytochrome c. more
total:17
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
ABR Affinity BioReagents anti-CHOP was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
total:6
Suppression of neuroblastoma growth by dipeptidyl peptidase IV: relevance of chemokine regulation and caspase activation. 2009 to the paper
Biomol anti-DPPIV antibody was used to perform immunohistochemistry in order to study the suppression of neuroblastoma growth performed by dipeptidyl peptidase IV. more
total:7
The nucleocapsid protein of severe acute respiratory syndrome coronavirus inhibits cell cytokinesis and proliferation by interacting with translation elongation factor 1alpha.. 2008 to the paper
UpState Biotechnology anti-EF1alpha antibody was used in western blot to study the effect of the interation between the nucleocapsid protein of severe acute respiratory syndrome coronavirus and translation elongation factor 1alpha on cell cytokinesis and proliferation. more
total:1
En masse analysis of nascent translation using microarrays. 2005 to the paper
ProteinTech Group polyclonal Eef1b2 antibody was used in western blot to study the en masse changes in translation in human carcinoma cells exposed to short-wavelength ultraviolet light (UVC).
total:4
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Cell Signaling Technology eEF2 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay. more
total:43
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
Abcam anti-eIF2alpha was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
total:2
BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer. 2007 to the paper
StressGen Biotechnologies anti-phospho eukaryotic initiation factor 2 beta (eIF2b) antibody was used in western blot to identify BBF2H7, a novel transmembrane bZIP transcription factor, as a new type of endoplasmic reticulum stress transducer. more
total:4
Pharmacological brake-release of mRNA translation enhances cognitive memory. 2013 to the paper
Abcam anti-phospho-S539 eIF2B epsilon antibody was used to perform western blot in order to investigate the molecular mechanism of memory consolidation. more
total:2
RNA CUG-binding protein 1 increases translation of 20-kDa isoform of CCAAT/enhancer-binding protein beta by interacting with the alpha and beta subunits of eukaryotic initiation translation factor 2. 2005 to the paper
Santa Cruz Biotech anti-eIF2beta antibody was used in western blot and immunoprecipitation to study the role of RNA CUG-binding protein 1 to 20-kDa isoform of CCAAT/enhancer-binding protein beta. more
total:1
The drosophila fragile X protein dFMR1 is required during early embryogenesis for pole cell formation and rapid nuclear division cycles. 2006 to the paper
Thomas Kaufman rabbit polyclonal anti-centrosomin antibody was used in immunohistochemistry to study the role of fragile X protein dFMR1 in the pole cell formation during early embryogenesis.
total:1
Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue. 2010 to the paper
Santa Cruz goat anti-eIF3B(N-20) polyclonal antibody(1:300) was used to perform immunohistochemistry and immunocytochemistry in order to study the TDP-43 associated with stress granules in cell culture and pathological CNS tissue.
total:1
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy. 2008 to the paper
Abcam rabbit anti-eIF3S8 antibody 1:15,000 was used for western blot in order to investigate the role of eIF4GI in the regulation of cell proliferation and autophagy.
total:1
The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation. 2010 to the paper
BioLegend anti-eIF3f polyclonal antibody was used to perform western blot in order to study the Notch activation regulated by deubiquitinase activity of eIF3f.
total:4
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. 2010 to the paper
Cell Signaling Technology anti-phospho-eIF4B antibody was used to carry out western blot analysis in order to investigate the precise contribution of 4E-BPs to mTORC1 signaling. more
total:37
Control of translation and miRNA-dependent repression by a novel poly(A) binding protein, hnRNP-Q. 2013 to the paper
BD BioSciences anti-eIF4E antibody was used to perform western blot in order to check the protein levels when hnRNP-Q was knocked down. more
total:5
Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. 2010 to the paper
Santa Cruz Biotechnology anti-EIF4G antibody was used to perform immunocytochemistry in order to study the interaction between TDP-43 and proteins that regulate RNA metabolism. more
total:1
Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virus. 2008 to the paper
Protein Tech Group anti-human eIF4H (WBSCR1) monoclonal antibody was used to perform western blot in order to study the siRNA of cellular translation factor eIF4H impeded herpes simplex virus (HSV) virion host shutoff (Vhs) protein inducing mRNA degradation.
total:1
The essential vertebrate ABCE1 protein interacts with eukaryotic initiation factors. 2006 to the paper
Dr. Umadas Maitra (Albert Einstein College of Medicine) anti-eIF5 antibody was used in western blot to study the role of ABCE1 in vertebrate translation initiation.
total:2
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. 2006 to the paper
Santa Cruz Biotechnology anti-IRE1alpha antibody was used in western blot to study the mechanism by which ER stress activates NF-kappaB and its role in regulation of ER stress-induced cell death in human cells. more
total:4
Endoplasmic reticulum chaperones stabilize nicotinic receptor subunits and regulate receptor assembly. 2007 to the paper
Stressgen anti-ERp57 Ab (1:2000 dilution) was used western blot to study the role of endoplasmic reticulum chaperones on nicotinic receptor subunits and assembly more
total:1
Genetic analysis of the subunit organization and function of the conserved oligomeric golgi (COG) complex: studies of COG5- and COG7-deficient mammalian cells. 2005 to the paper
BD Biosciences anti-Sec8 antibody was used in western blot to study the Subunit organization and function of the conserved oligomeric golgi (COG) complex.
total:1
Cell-cell contact globally activates microRNA biogenesis. 2009 to the paper
Upstate anti-Ago antibody was used to perform western blot in order to study the association between the cell-cell contact and microRNA biogenesis.
total:1
Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia. 2009 to the paper
Santa Cruz Biotechnology frataxin antibody was used in immunohistochemistry in order to suggest that the defective machinery for ISP synthesis affect the oxidative stress response in friedreich ataxia.
total:2
Changes in serum inhibin B during normal male puberty. 2005 to the paper
Autodelfia anti-FSH antibody was used in immunocytochemistry to study the changes in serum inhibin B during normal male puberty. more
total:1
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
Invitrogen anti-Core2 antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA.
total:2
The mitochondrial disulfide relay system protein GFER is mutated in autosomal-recessive myopathy with cataract and combined respiratory-chain deficiency. 2009 to the paper
Proteintech Group anti-GFER antibody was used to perform immunocytochemistry in order to study the mechanisms of mitochondrial biogenesis and the roles of GFER in the human DRS. more
total:7
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. 2010 to the paper
Invitrogene anti-beta-Galactosidase antibody was used in immunocytochemistry for immunofluorescent staining to investigate the role of the NMDA receptors in the regulation of nicotine-conditioned place preference in dopamine neurons. more
total:13
Deletion of the mitochondrial flavoprotein apoptosis inducing factor (AIF) induces beta-cell apoptosis and impairs beta-cell mass. 2009 to the paper
Sigma anti-glucagon antibody was used to perform immunohistochemistry in order to study the role of mitochondrial flavoprotein apoptosis inducing factor. more
total:3
A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels. 2009 to the paper
Abcam membrin antibody was used in immunocytochemistry in order to investigate the role of SNARE complex containing VAMP7 and Vti1a in the regulation of a novel traffic pathway to the cell surface in both neuronal and non-neuronal cells. more
total:10
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
Stressgen anti-GRP94 was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
total:23
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Santa Cruz Biotechnology anti-GSK3 alpha antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
total:4
Metastatic embryonal carcinoma in the maxillary gingiva. 2008 to the paper
DAKO anti-HCG antibody was used to perform immunohistochemistry in order to study the metastases of embryonal carcinoma in the maxillary gingiva. more
total:1
Overexpressed HDGF as an independent prognostic factor is involved in poor prognosis in Chinese patients with liver cancer. 2010 to the paper
Proteintech Inc rabbit anti-human HDGF antibody(1:100) was used to perform immunohistochemistry in order to study the role of overexpressed HDGF in prognosis in Chinese patients with liver cancer.
total:2
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Abgent anti-Herp antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:21
Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. 2008 to the paper
Santa Cruz polyclonal anti-Hsp60 was used to perform immunocytochemistry in dilution 1:500 in order to show that acetylshikonin and analogues induce apoptosis through orphan nuclear receptor Nur77-mediated apoptotic pathway in cancer cells. more
total:3
Depletion of kinesin 5B affects lysosomal distribution and stability and induces peri-nuclear accumulation of autophagosomes in cancer cells. 2009 to the paper
Stressgene anti-GRP75 antibody (SPA825) was used in western blot to study the role for kinesin 5B in cancer cells. more
total:13
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
Abcam rabbit anti-IGF-1 antibody was used in western blot to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
total:17
IGFBP3 colocalizes with and regulates hypocretin (orexin). 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-human IGFBP3 antibody was used in western blot to study the association of IGFBP3 with hypocretin. more
total:2
A 14-kDa cathepsin L-derived carboxyl IGFBP-2 fragment is sequestered by cultured rat ileal crypt cells. 2005 to the paper
Santa Cruz Biotechnology IGFBP2 antibody was used in western blot and immunohistochemistry to demonstrate that dexamethasone alters proteolytic regulation of IGFBP-2 in ileal crypt cells. more
total:1
Interaction of insulin-like growth factor II (IGF-II) with multiple plasma proteins: high affinity binding of plasminogen to IGF-II and IGF-binding protein-3. 2005 to the paper
R&D Systems polyclonal antibody against IGFBP-5 was used in western blot to study the interaction of insulin-like growth factor II (IGF-II) with multiple plasma protein.
total:1
Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts. 2005 to the paper
Santa Cruz Biotechnology polyclonal 1:200 dilutied IGFBP-6 antibody was used in western blot to identify IGFBP-6 as a sensitive biomarker of cell degeneration or injury in vitro and in vivo..
total:46
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
R&D systems anti-IL8 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
total:1
GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin. 2005 to the paper
Abcam anti-KIF5A (1007 1027) antibody was used in western blot to characterize GRIF-1 and OIP106 and to study their associaiton with kinesin
total:5
Depletion of kinesin 5B affects lysosomal distribution and stability and induces peri-nuclear accumulation of autophagosomes in cancer cells. 2009 to the paper
Abcam anti-KIF5B antibody ab5629 was used in western blot to study the role for kinesin 5B in cancer cells. more
total:4
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Santa Cruz KHC antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
total:57
RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins. 2013 to the paper
Santa Cruz lamin A/C goat polyclonal (1:1000)was used to perform the immunoblotting to study the translation of a subset of mRNAs encoding secretory proteins potentiated by RanBP2/Nup358. more
total:4
Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. 2010 to the paper
Sigma rabbit polyclonal anti-ERGIC-53 antibody (1:1000) was used in western blot in order to study the regulation of autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. more
total:4
Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker. 2005 to the paper
Chemicon Int. anti-mannosidase II antibody was used in immunocytochemistry to study the tumor-specificity of both (22-1-1 and EBAG9) and the role in induction of apoptosis in human tumor cells. more
total:14
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
Santa Cruz anti-MCP-1 antibody was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
total:13
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 to the paper
Calbiochem anti-MMP-1 monoclonal antibody was used to perform western blot in order to study the role of CD147 promoted myofibroblast differentiation in tissue remodeling. more
total:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 to the paper
Santa Cruz monoclonal MMP-2 antibodies were used in western blot in order to investigate the role of matrix metalloproteinase-2 (MMP-2) gene in invasiveness and adhesion of human pancreatic cancer cell line, BxPC-3. more
total:28
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Lab Vision anti-MUC1-C antibody was used to perform immunoprecipitation in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers. more
total:8
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. 2006 to the paper
Santa cruz biotechnology anti-Muc2 antibody was used to perform mmunohistochemistry assays in order to investigate the molecular regulation mechanisms of Smad4 in the process of normal pancreas development and pancreatic ductal adenocarcinomas (PDAC) growth. more
total:5
The clinicopathological and prognostic significance of MUC-1 expression in Japanese gastric carcinomas: an immunohistochemical study of tissue microarrays. 2008 to the paper
NovoCastra anti-human MUC-4 antibody was used to perform immunohistochemistry in order to study the clinicopathological significance of MUC-1 expression in gastric carcinomas. more
total:10
TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells. 2013 to the paper
Neomarkers anti-MUC5AC antibody was used to perform western blot and immunocytochemistry in order to investigate the regulatory effect of TRPM5 activation on MUC5AC secretion from human colon goblet cells. more
total:4
Mixed-type gastric carcinomas exhibit more aggressive features and indicate the histogenesis of carcinomas. 2008 to the paper
Novocastra mouse anti-MUC-6 antibody was used in immunohistochemistry to investigate the pathobiological behaviors of gastric mixed-type (MT) carcinomas and gastric carcinogenesis. more
total:1
Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility. 2007 to the paper
Sigma rabbit polyclonal anti-myosin V antibody was used to carry out western blot analysis in order to investigate the role for UNC-45 in the regulation of tumor cell proliferation and metastasis.
total:1
N-acetylglucosaminyltransferase V and beta1-6 branching N-linked oligosaccharides are associated with good prognosis of patients with bladder cancer. 2006 to the paper
Monoclonal antibody against human GnT-V SKNTDFFIGKPTILRELTS (Chikara Ohyama, Department of Urology, Hirosaki University School of Medicine) was used in immunohistochemistry to examine the relationship between GnT-V expression and clinicopathologic features of the patients with bladder cancer.
total:1
Expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. 2007 to the paper
Rockland anti-human neuraminidase 1 antibody was used in western blot and immunoprecipitation to study the expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients.
total:9
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Santa Cruz p150Glued antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
total:7
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal anti-PABP antibody(10E10, 1:200) was used to perform immunofluorescence in order to characterize the TAR DNA-binding Protein-43's alternative isoforms inclusion body. more
total:14
The role of nitric-oxide synthase in the regulation of UVB light-induced phosphorylation of the alpha subunit of eukaryotic initiation factor 2. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-PERK antibody was used in immunoprecipitation in order to demonstrate that UVB-induced eIF2 phosphorylation is regulated by NOS. more
total:4
Borrelia burgdorferi infection-associated surface proteins ErpP, ErpA, and ErpC bind human plasminogen. 2009 to the paper
Novus Biologicals goat anti-human plasminogen antibody was used to perform ELISA in order to study human plasminogen binding surface proteins ErpP, ErpA, and ErpC in Borrelia burgdorferi infection. more
total:18
Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. 2008 to the paper
DAKO polyclonal anti-PSA antibody was used in immunohistochemistry in order to investigate mechanisms by which advanced prostate cancers maintain AR-mediated gene expression following castration more
total:6
A novel missense mutation (G43S) in the switch I region of Rab27A causing Griscelli syndrome. 2008 to the paper
BD Biosciences mouse monoclonal Rab27A antibody was used in western blot in order to study the role of Switch I region in the recruitment of Rab effector proteins. more
total:2
Expression of components of the renin-angiotensin system in autosomal recessive polycystic kidney disease. 2005 to the paper
Dr. Tadashi Inagami renin antibody was used in immunohistochemistry to study the expression of components of the renin-angiotensin system in autosomal recessive polycystic kidney disease. more
total:1
Overexpression of ribosomal protein L15 is associated with cell proliferation in gastric cancer. 2006 to the paper
Neomarker anti-RPL15 antibody was used in western blot and immunohistochemistry to study the relation between overexpression of ribosomal protein L15 and cell proliferation in gastric cancer.
total:1
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. 2008 to the paper
Bethyl Laboratories rabbit anti-Rpl26 antibody was used for western blot in order to investigate the role of nucleolar protein B23 in the regulation of the vertebrate SUMO pathway.
total:1
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. 2008 to the paper
Abnova rabbit anti-RPL37A antibody was used for western blot in order to investigate the role of nucleolar protein B23 in the regulation of the vertebrate SUMO pathway.
total:3
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Cell Signaling Technology rpS3 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay. more
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Invitrogen rpL11 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:2
RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits. 2010 to the paper
Abcam goat anti-human RPL7 antibody was used to perform western blot in order to study the role of RRP1B and PP1 in mammalian cell nucleoli and pre-60S ribosomal subunits. more
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Cell Signaling Technology rpL7a antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:1
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. 2008 to the paper
Proteintech Group rabbit anti-RplP0 antibody was used for western blot in order to investigate the role of nucleolar protein B23 in the regulation of the vertebrate SUMO pathway.
total:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 to the paper
Abcam rpS16 antibody was used in western blot in order to study the regulatory mechanism of SMG-1 kinase in nonsense-mediated mRNA decay.
total:3
Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylation. 2009 to the paper
Millipore anti-Mps1 antibody was used to perform immunohistochemistry in order to study the regulation of Mps1 phosphorylation in kinetochore targeting and spindle checkpoint signaling. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:36
p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. 2012 to the paper
Cell Signalling anti-S6 (rabbit monoclonal) antibody was used to perform immunoblotting in order to study the effect of p180 on the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. more
total:2
67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells. 2005 to the paper
Abcam polyclonal 67LR antibody (Ab711) was used in western blot and immunoprecipitation to study the role of 67-kDa Laminin Receptor Escherichia coli K1 internalization in human brain microvascular endothelial cells more
total:2
Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone. 2006 to the paper
Abcam anti-SAE1(ab5645) antibody was used to perform western blot in order to study the process of cAMP signaling induced dynamic changes in the SUMO pathway determine the endometrial response to progesterone. more
total:3
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents Sec23 antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
total:1
Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. 2009 to the paper
Proteintech Group anti-KDEL was used to perform immunofluorescence and immunogold labeling in order to demonstrate that pathogen-driven hER-PV interaction can faciliate Ag entry into the MHC class I pathway and CD8+ T cell.
total:3
Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts. 2007 to the paper
Abgent polyclonal anti-SENP1 antibody was used to perform western blot in order to study the regulation of Fas-induced apoptosis by SUMO-1 more
total:2
Nitric oxide destabilizes Pias3 and regulates sumoylation. 2007 to the paper
Santa Cruz polyclonal anti-Senp2 was used to perform western blot in order to show that global sumoylation and Pias3 stabilization could be regulated by nitric oxide. more
total:20
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Cell Signalling anti-ShcA and anti-phospho-ShcA (Tyr239/240) antibodies were used to perform western blot in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
total:3
Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-ANT antibody was used for western blot in order to investigate the role of Ischaemic preconditioning in the regulation of proteasomal activity and the degradation of PKCdelta during reperfusion. more
total:1
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. 2007 to the paper
Oncogene Research Products SphK1 antibody was used in western blot to study the role of lipid phosphate phosphatase (LPP) 1 and sphingosine kinase1 (SphK1) in converting exogenous S1P to intracellular S1P.
total:40
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Abcam anti-SUMO1 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
total:7
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 to the paper
Abcam anti-SUMO2/3 was used to perform western blot in order to show that Myc-dependent cancer needs SUMOylation for tumorigenesis. more
total:1
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein. 2006 to the paper
Zymed Laboratories anti-SUMO3 antibody was used in western blot to detect SUMO3 in HEK293 cells co-transfected with His-SUMO isoforms (SUMO1, SUMO2, and SUMO3) and full-length human tau or alpha-synuclein.
total:11
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-syntaxin-1 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
total:2
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
Santa Cruz biotechnology anti-synoviolin mAb was used to perform immunocytochemistry in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:10
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Serotec anti-talin antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more
total:1
Focal adhesion components are essential for mammalian cell cytokinesis. 2008 to the paper
Sigma tubulin antibody was used to perform western blot in order to study the function of focal adhesion components in mammalian cell cytokinesis.
total:1
Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells. 2010 to the paper
Protein-Tech Group anti-TBCE antibody(1:500) was used to perform western blot in order to study the recognition of CML Progenitor Cells expressed antigens by Efficacious Immune Therapy in Chronic Myelogenous Leukemia (CML).
total:20
Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. 2009 to the paper
Acbam mouse monoclonal antibody against human and mouse thrombospondin-1 was used in immunohistochemistry to investigate the role of transforming growth factor Beta signaling in the regulation of tumor growth. more
total:3
The mitochondrial disulfide relay system protein GFER is mutated in autosomal-recessive myopathy with cataract and combined respiratory-chain deficiency. 2009 to the paper
Proteintech Group anti-COX17 antibody was used to perform immunocytochemistry in order to study the mechanisms of mitochondrial biogenesis and the roles of GFER in the human DRS. more
total:1
MCU encodes the pore conducting mitochondrial calcium currents. 2013 to the paper
BD Biosciences anti-TIMM23 antibody was used to perform western blot in order to investigate the functional property of the MCU gene.
total:6
MCU encodes the pore conducting mitochondrial calcium currents. 2013 to the paper
Santa Cruz Biotechnology anti-TOMM20 antibody was used to perform western blot in order to investigate the functional property of the MCU gene. more
total:1
Functional dissection of human and mouse POT1 proteins. 2009 to the paper
Sigma rabbit anti-humanTPP1 (1151) antibody was used in western blot in order to investigate the function of single-stranded telomeric DNA associated protein-POT1 in human and mice.
total:5
Bone marrow cells produce a novel TSHbeta splice variant that is upregulated in the thyroid following systemic virus infection. 2009 to the paper
Santa Cruz Biotechnology anti-TSHb antibody was used to carry out immunopreciptation assays in order to characterize the function of a novel TSH splice variant during immunological stress. more
total:117
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Sigma mouse anti-alpha-tubulin was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:11
The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA. 2013 to the paper
Santa Cruz anti-alpha-tubulin antibody was used to perform western blot in order to investigate the regulatory effect of HILDA complex on VEGF-A expression. more
total:1
Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. 2009 to the paper
Lab Vision antitubulin antibody was used in western blot in order to study the role of TRAIL for activation of DNA damage response pathways with histone H2AX and Chk2 phosphorylations.
total:4
Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP. 2009 to the paper
Santa Cruz Biotech anti tubulin antibody (1:3,000) was used to perform western blot in order to study the rescuing function of human IKBKAP in the embryonic lethality resulting from mouse Ikbkap ablation. more
total:37
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Chemicon anti-B-Tubulin antibody was used to perform immunohistochemistry in order to study synaptic plasticity. more
total:2
Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia. 2005 to the paper
Sigma monoclonal beta IV-tubulin antibody was used in immunohistochemistry to characterize wild-type and mutant cystic fibrosis transmembrane regulator in human respiratory epithelia more
total:2
Nitric oxide destabilizes Pias3 and regulates sumoylation. 2007 to the paper
BD Pharmingin monoclonal anti-Uba2 was used to perform western blot in order to show that global sumoylation and Pias3 stabilization could be regulated by nitric oxide. more
total:10
The forkhead transcription factor Foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity. 2010 to the paper
Santa Cruz anti-UBC9 antibody was used in western blot in order to find the counterpart of forkhead transcription factor- FOXL2 and elucidate the role of its sumoylation more
- UDP GalNAc polypeptide N acetylgalactosaminyltransferase antibody
- UDP GalNAc polypeptide N acetylgalactosaminyltransferase gene knockdown
- UDP GalNAc polypeptide N acetylgalactosaminyltransferase cDNA
- UDP GalNAc polypeptide N acetylgalactosaminyltransferase protein
- UDP GalNAc polypeptide N acetylgalactosaminyltransferase other
- UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltrans antibody
- UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltrans gene knockdown
- UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltrans cDNA
- UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltrans other
total:8
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
SYSY monoclonal anti-synaptobrevin-2 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
total:20
Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity. 2011 to the paper
Abcam anti-porin antibody was used to perform immunoprecipitation in order to reveal how viperin facilitates the infectious process. more
total:3
Pharmacological brake-release of mRNA translation enhances cognitive memory. 2013 to the paper
BioLegend anti-XBP1s antibody was used to perform western blot in order to investigate the molecular mechanism of memory consolidation. more
total:1
Pause sites promote transcriptional termination of mammalian RNA polymerase II. 2006 to the paper
Eurogentec rabbit polyclonal anti-Xrn2 antibody was raised against an N-terminal fragment (amino acids 1 to 298) of Xrn2 was used in western blot to detect Xrn2 in HeLa cells.
total:3
Gfi-1 represses CDKN2B encoding p15INK4B through interaction with Miz-1. 2009 to the paper
Santa Cruz Biotechnology Miz-1 (N17) was used in coimmunoprecipitation assays in order to study the mechanism of Gfi-1 repressing CDKN2B and then encoding p15INK4B through interaction with Miz-1 more