Metabolism of lipids and lipoproteins
gene
reagent
sample publication
sample review
total:10
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Abcam mouse monoclonal anti-ABCA1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
total:3
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Kamiya Biomedical rabbit anti-Bsep antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes. more
total:1
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Signet Laboratories mouse anti-MDR antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes.
total:6
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Novus rabbit polyclonal anti-ABCG1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
total:17
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
Upstate Biotechnologies anti-ACC1 S79ph antibody was used to carry out western blot analysis in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:2
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. 2009 to the paper
Cayman ACAT-1 antibody was used for western blot in order to investigate the role of mitochondria in endothelial cell dysfunction. more
total:1
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate. 2008 to the paper
Novus Biologicals anti-Facl3 antibody was used for western blot in order to investigate the roles of elenium and isoflavones in the regulation of androgen-regulated gene expression in healthy rat dorsolateral prostate.
total:6
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 to the paper
IgG corporation rabbit polyclonal anti-ang II serum was used in immunohistochemistry in order to study the glomerular AGT's expression and its correlation with expression of other RAS components more
total:1
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. 2009 to the paper
Abcam anti-AKR1D1 antibody was used to perform western blot in order to study the novel BRAF fusion gene in 7q34 duplication of pediatric low-grade astrocytomas detected by high density SNP-based genotype array analysis.
total:11
Human microglial cells synthesize albumin in brain. 2008 to the paper
R&D system mouse anti-human-albumin antibody was used in immunohistochemistry and immunocytochemistry in order to study the expression of albumin in human microglial cells and brain tissues. more
total:2
Role of 12-lipoxygenase in volatile anesthetic-induced delayed preconditioning in mice. 2006 to the paper
Cayman Chemical 12-LO primary antibody was used in western blot to study the role of 12-lipoxygenase in volatile anesthetic-induced delayed preconditioning in mice. more
total:6
A mutant of hepatitis B virus X protein (HBxDelta127) promotes cell growth through a positive feedback loop involving 5-lipoxygenase and fatty acid synthase. 2010 to the paper
Santa Cruz Biotechnology anti-5-LOX antibody was used to perform western blotting in order to study how the cell growth are promoted by research on a mutant of HBx. more
total:3
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer. 2008 to the paper
Dako anti-AMACR(13H4) antibody was used to perform immunohistochemistry in order to study the expression of cytokeratin 7 and 19 are related with genomic stability and favorable prognosis in clear cell renal cell cancer. more
total:1
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. 2005 to the paper
Karen S. L. Lam (University of Hong Kong, China) monoclonal ANGPTL4 antibody was used in ELISA to study its effect in mice
total:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 to the paper
Abcam polyclonal rabbit anti-apoA-I antibody (1:10,000) was used for western blot in order to investigate the distinct roles of apolipoprotein components in a transgenic mouse model. more
total:1
The expression of intact and mutant human apoAI/CIII/AIV/AV gene cluster in transgenic mice. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal human apoAIV antibody was used in western blot to study the expression of human apoAI/CIII/AIV/AV in transgenic mice
total:2
Serum amyloid P colocalizes with apolipoproteins in human atheroma: functional implications. 2007 to the paper
Calbiochem rabbit polyclonal apoC-II antibody was used in immunohistochemistry to study the colocalization of serum amyloid P with apolipoproteins in human atheroma more
total:19
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Calbiochem anti-ApoE antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:14
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Abcam anti-ApoB100 antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:8
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. 2007 to the paper
Affinity Bioreagents anti-Arf antibody was used to perform western blot in order to study the interaction between Arf and Poliovirus Protein 3CD and its effect on poliovirus replication. more
total:4
GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome. 2008 to the paper
Santa Cruz Biotechnology goat anti-CYP19 (1:200) polyclonal antibody was used to perform immunohistochemistry in order to study the physiological functions of GPRC6A. more
total:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 to the paper
Epitomics anti-ATP-citrate lyase antibody was used to perform western blot in order to study the cytotoxicity of timosaponin AIII towards tumor cells.
total:1
Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation. 2005 to the paper
Affinity Bioreagents polyclonal anti-BMP-1 antibody (recognizing the CUB-2 domain) was used in western blot to study the binding of cellular fibronectin with lysyl oxidase
total:3
The C-terminal domain of RNA polymerase II is modified by site-specific methylation. 2011 to the paper
Bethyl Laboratories anti-CARM1 antibody was used to perform immunocytochemistry in order to reveal that methylation of the carboxy-terminal domain of RNA polymerase II facilitates the expression of some RNAs. more
total:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 to the paper
Santa Cruz Biotechnology anti-CBP antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathway more
total:2
Differential expression of prostaglandin (PG) synthesis enzymes in conceptus during peri-implantation period and endometrial expression of carbonyl reductase/PG 9-ketoreductase in the pig. 2007 to the paper
Abcam 1:2000 polyclonal anti-human CBR1 antibody was used in western blot to study the role of prostaglandins (PGs) in luteolysis, maternal recognition of pregnancy, and implantation. more
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:1
LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia. 2005 to the paper
Sigma Chemical monoclonal anti-V5 peroxidase-conjugated antibody was used in western blot to demonstrate that LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia
total:8
Sustained expression of TDP-43 and FUS in motor neurons in rodent's lifetime. 2010 to the paper
Millipore goat ChAT antibody was used to perform immunohistochemistry in order to clarify important roles of TDP-43 and FUS in motor neurons to the selectivity of the neurotoxicity. more
total:11
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Santa Cruz Biotechnologies CTGF antibody (1:2,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
total:1
Coimmunoprecipitation of FAT/CD36 and CPT I in skeletal muscle increases proportionally with fat oxidation after endurance exercise training. 2006 to the paper
Santa Cruz Biotechnology polyclonal antibody against CPT I was used in immunoprecipitation to isolate CPT I from human skeletal muscle.
total:3
Expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. 2007 to the paper
Rockland anti-human PPCA antibody was used in western blot to study the expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. more
total:15
Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer. 2009 to the paper
Chemicon International anti-CYP 1A1 antibody (AB1258) was used in western blot to determine the functional significance of aryl hydrocarbon receptor (AhR) in gastric carcinogenesis, and to explore the possible role of AhR in gastric cancer (GC) treatment more
total:2
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Alexis Biochemicals mouse anti-Mrp2 antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes. more
total:8
Preferential induction of cytochrome P450 1A1 over cytochrome P450 1B1 in human breast epithelial cells following exposure to quercetin. 2008 to the paper
Santa Cruz affinity purified goat polyclonal Cyp1B1 antibody was used in western blot in order to study the role of estrogen metabolism in estrogen-induced breast carcinogenesis more
total:1
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 to the paper
Santa Cruz anti-CYP24A1 (1:150) polyclonal antibody was used to perform immunocytochemistry in order to show that cathelicidin, a human antimicrobial peptide can be induced by vitamin D in the urinary bladder.
total:1
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 to the paper
Santa Cruz anti-CYP27B1 (D-20, 1:200) polyclonal antibody was used to perform immunocytochemistry in order to show that cathelicidin, a human antimicrobial peptide can be induced by vitamin D in the urinary bladder.
total:3
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. 2009 to the paper
BD Biosciences-Pharmingen monoclonal anti-cytochrome c antibody was used in immunohistochemistry in order to introduce a rapid regulation of mitochondrial dynamics in acute kidney injury. more
total:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 to the paper
BD Gentest anti-CYP2C9 antibody (1:1000) was used in western blot in order to study the role of cardiomyocyte CPR and CPR-dependent enzymes in doxorubicin (Dox) mediated acute cardiotoxicity more
total:1
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 to the paper
Proteintech polyclonal anti-CYP4F11 antibody was used to perform western blot in order to clarify that retinoic acid could inhibit CYP4F11 expression in human keratinocyte-derived HaCaT cells by multiple signaling pathways including RXR and JNK pathways.
total:1
Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development. 2007 to the paper
Invitrogen DecR1 antibody was used in western blot to study the role of DecR1 in mammary tumor development.
total:1
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Santa Cruz anti-DGAT1 antibody was used in western blot, immunocytochemistry and immunoprecipitation to study the formation requirement of efficient hepatitis C virus particle.
total:1
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate. 2008 to the paper
Proteintech Group Inc anti-Dhcr24 antibody was used for western blot in order to investigate the roles of elenium and isoflavones in the regulation of androgen-regulated gene expression in healthy rat dorsolateral prostate.
total:2
One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis. 2008 to the paper
Proteintech Group rabbit polyclonal anti-ECHS1 antibody was used for western blot in order to study the effect of altered proteome of morphologically normal colon crypts on familial adenomatous polyposis. more
total:1
Haploinsufficiency is not the key mechanism of pathogenesis in a heterozygous Elovl4 knockout mouse model of STGD3 disease. 2006 to the paper
Abcam rabbit polyclonal anti-ELOVL4 antibody was used in western blot to characterize a mouse model with a targeted deletion of Elovl4 and to explore the role of this gene in retinal/macular degeneration.
total:1
Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. 2010 to the paper
R&D Systems goat anti-human L-FABP polyclonal antibody was used to perform western blot in order to study the prognostic ability of urinary liver-type fatty acid-binding protein (L-FABP) in Acute kidney injury (AKI).
total:2
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-A-FABP antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis. more
total:6
Fatty acid synthase expression in cutaneous melanocytic neoplasms. 2005 to the paper
Immuno-Biological Laboratories anti-fatty acid synthase antibody was used in immunohistochemistry to study expression of fatty acid synthase in cutaneous melanocytic neoplasms. more
total:4
Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway. 2009 to the paper
Santa Cruz Biotechnology anti-FHL2 antibody was used for western blot to study the suppressing role of human FHL1 family members in the modulation of tumor cell growth through a TGF-beta like signaling pathway. more
total:1
The Dickkopf-homolog 3 is expressed in tumor endothelial cells and supports capillary formation. 2008 to the paper
R&D systems mouse Dkk-3 monoclonal antibody was used to perform western blot in order to study the expression of Dkk-3 in various solid tumor types.
total:2
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GLA polyclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease. more
total:7
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. 2010 to the paper
Invitrogene anti-beta-Galactosidase antibody was used in immunocytochemistry for immunofluorescent staining to investigate the role of the NMDA receptors in the regulation of nicotine-conditioned place preference in dopamine neurons. more
total:1
Central role of Gq in the hypertrophic signal transduction of angiotensin II in vascular smooth muscle cells. 2008 to the paper
Chemicon glyceraldehyde-3-phosphate dehydrogenase antibody was used in western blot in order to demonstrate that Gq coupling of the AT1 receptor is essential for the EGFR transactivation and subsequent VSMC hypertrophy induced by AngII
total:3
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. 2009 to the paper
Affinity BioReagents ATP synthase antibody was used for western blot in order to investigate the role of mitochondria in endothelial cell dysfunction. more
total:1
COMMD1 expression is controlled by critical residues that determine XIAP binding. 2009 to the paper
Stressgen anti-SCHAD was used to perform immunoprecipitation in order to show that the expression of COMMD1 is regulated while COMMD1 and XIAP interact with each other via some critical residues
total:1
Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity. 2011 to the paper
Lifespan Biosciences anti-HADHB antibody was used to perform western blot in order to reveal how viperin facilitates the infectious process.
total:21
Histone deacetylase complexes promote trinucleotide repeat expansions. 2012 to the paper
Santa Cruz Biotechnology anti-HDAC3 antibody was used to perform western blot assay in order to identify novel histone deacetylase complexes that promote expansions of trinucleotide repeats. more
total:1
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-HMGCR antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism.
total:1
Quantitation and cellular localization of 11beta-HSD1 expression in murine thymus. 2006 to the paper
Dr. Zygmunt Krozowski (Baker Heart Research Institute) 11beta-HSD1 antibody was used in western blot to assess 11beta-HSD1 protein expression in whole tissues.
total:1
Quiescent fibroblasts exhibit high metabolic activity. 2010 to the paper
Lifespan Biosciences anti-IDH1 antibody was used to perform western blot in order to study the function of quiescent fibroblasts.
total:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 to the paper
Protein Tech Group anti-IDI1 antibody was used to perform western blot in order to study the cytotoxicity of timosaponin AIII towards tumor cells.
total:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 to the paper
Biovision anti-INSIG-1 antibody was used to perform western blot in order to study the cytotoxicity of timosaponin AIII towards tumor cells.
total:7
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. 2010 to the paper
Santa Cruz Biotechnology mouse alpha-importin beta antibody (sc-137016) was used to perform western blot, immunoprecipitation, and immunofluorescence in order to identify WRAP53 as an essential factor for Cajal body maintenance and for directing the SMN complex to Cajal bodies. more
total:10
Induction of a massive endoplasmic reticulum and perinuclear space expansion by expression of lamin B receptor mutants and the related sterol reductases TM7SF2 and DHCR7. 2010 to the paper
Epitomics rabbit monoclonal anti-LBR antibody was used in western blot and immunohistochemistry in order to investigate the effects of the expression of human LBR disease mutants on cellular structure. more
total:10
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 to the paper
Santa Cruz anti-LDLr antibody was used in western blot in order to show that Wnt/catenin signaling, osteoblast function, and bone formation can be negatively regulated by the N-cadherin-axin-LRP5 interaction. more
total:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz polyclonal anti-MED1 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:18
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Cell Signaling Technology anti-MAPKAPK 2 (pT334) was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:15
Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex. 2010 to the paper
Abcam anti-Sin3a trimethyl was used to perform western blot in order to study the role of deacetylase inhibitors to ING2 subunit from the Sin3 complex. more
total:1
The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 2009 to the paper
Abgent anti-MTMR4 antibody was used to perform western blot in order to study the role of Nedd4 plays in the biological process of muscle breakdown.
total:6
Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. 2006 to the paper
BD Biosciences mouse monoclonal anti-TIF2 antibody was used in western blot (1:500) and immunohistochemistry (1:500) to assess the consequences of reducing expression of the transcription intermediary factor 2 (TIF2) coactivator on prostate cancer cell growth. more
total:1
Characterization of activating signal cointegrator-2 as a novel transcriptional coactivator of the xenobiotic nuclear receptor constitutive androstane receptor. 2005 to the paper
anti-ASC-2 antibody was used in immunoprecipitation to study the characterization of activating signal cointegrator-2 as a novel transcriptional coactivator of the xenobiotic nuclear receptor constitutive androstane receptor.
total:14
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Upstate Biotechnology anti-p300 antibody was used to perform western blot in order to show that IRF5 mediated the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:1
Expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. 2007 to the paper
Rockland anti-human neuraminidase 1 antibody was used in western blot and immunoprecipitation to study the expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients.
total:13
Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-NF-YA antibody was used in immunoblot in order to study the role of tuberin and OGG1 in the pathogenesis of angiomyolipoma in TSC patients. more
total:1
The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response. 2008 to the paper
Santa Cruz rabbit polyclonal anti-NPAS2 antibody was used to perform western blot in order to show that circadian gene NPAS2 is a putative tumor suppressor involved in DNA damage response.
total:1
Endurance exercise as a countermeasure for aging. 2008 to the paper
SantaCruz anti-NRF-1 antibody was used in western blot in order to investigate whether the mitochondrial dysfunction and reduced insulin sensitivity are inevitably caused by aging.
total:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-p110alpha was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:43
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Upstate anti-p85 pAb was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:1
Peripherally-derived BDNF promotes regeneration of ascending sensory neurons after spinal cord injury. 2008 to the paper
List Biological Labs CTB antibody was used in immunohistochemistry to study the role of BDNF in the regeneration of central axons of ascending sensory.
total:5
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. 2006 to the paper
Chemicon monoclonal anti-perlecan antibody (MAB 1948) was used in frozen sections from mouse and in immunohistochemistry to study the identification of WARP as a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. more
total:4
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. 2005 to the paper
Oxford Biomedical Research mouse monoclonal PGIS antibody was used in western blot to demonstrate that the mPGES-1 enzyme is a primary release mechanism of PGH2 accumulation. more
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
P. de Camilli anti-PI4KII alpha antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
total:1
Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol. 2010 to the paper
Proteintech group Inc anti-PI4KCA antibody was used to perform western blot in order to study the modulation of intracellular F. tularensis phagosome biogenesis and proliferation.
total:3
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. 2009 to the paper
Abgent anti-PI3KC3 antibody was used in western blot in order to study the role of Beclin 1 in the regulation of autophagy. more
total:6
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz polyclonal anti-p110beta antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:5
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz anti-p110delta monoclonal antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:11
Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation. 2006 to the paper
Santa Cruz Biotechology anti-p110 gamma antibody was used in western blot in order to investigate the mechanism of the PI3K-IA (phosphatidylinositol 3-kinase Class IA) lipid kinase activity was affected by high NaCl and ionizing radiation. more
total:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Millipore polyclonal anti-human p85 antibody was used to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:1
Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. 2008 to the paper
Abgent rabbit anti-hVps15 antibody was used in western blot to identify the pathway and mechanism by which AAs signal to hVps34 to stimulate mTOR complex1 signaling.
total:1
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-PIP5K1alpha antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation.
total:1
Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl. 2009 to the paper
Abgent anti-PIP5KI antibody was used to perform western blot in order to study the role of wnt3a and dvl in phosphatidylinositol kinase regulation.
total:5
Effect of retinoic acid on gene expression in human conjunctival epithelium: secretory phospholipase A2 mediates retinoic acid induction of MUC16. 2005 to the paper
Upstate mouse monoclonal sPLA2 antibody was used in western blot to identify vitamin A-responsive genes in ocular surface epithelia. more
total:8
Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport.. 2009 to the paper
Santa Cruz Biotechnology anit-cPLA2a antibody was used to perform western blot and immunocytochemistry to study the role of cPLA2a in the formation of intercisternal tubular continuities and transport through the Golgi complex. more
total:1
OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity. 2009 to the paper
Invitrogen FLAG antibody was used to perform immunoprecipitation in order to investigate the relations between Dok-4 and T cell.
total:1
Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway. 2005 to the paper
Novus Biologicals PLD2 antibody was used in immunoprecipitation to study ABCA1 phosphorylation and degradation
total:2
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 to the paper
Santa Cruz anti-ADRP antibody was used in western blot to study the formation requirement of efficient hepatitis C virus particle. more
total:1
Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific. 2008 to the paper
Cayman Chemical polyclonal ATGL antibody was used in immunohistochemistry in order to study the expression pattern of ATGL in human skeletal muscle
total:19
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. 2008 to the paper
Santa Cruz anti-PP1alpha was used to perform western blot in order to show that SRC-3/AIB1 coactivator function and turnover is regulated by essential phosphatases and a phospho-degron of SRC-3/AIB1 is primary determinants of its turnover. more
total:2
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. 2007 to the paper
Sigma LPP-3 antibody was used in western blot to study the role of lipid phosphate phosphatase (LPP) 1 and sphingosine kinase1 (SphK1) in converting exogenous S1P to intracellular S1P. more
total:1
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. 2007 to the paper
Sigma LPP-2 antibody was used in western blot to study the role of lipid phosphate phosphatase (LPP) 1 and sphingosine kinase1 (SphK1) in converting exogenous S1P to intracellular S1P.
total:9
Integration of microRNA miR-122 in hepatic circadian gene expression. 2009 to the paper
Abcam rabbit polyclonal antibody PPAR was used for immunoprecipitation in order to study the circadian gene expression of integration of microRNA miR-122 in hepatic. more
total:2
Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma. 2007 to the paper
Santa Cruz Biotechnology goat polyclonal PP1 gamma C antibody was used in western blot to study the regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma more
total:4
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 to the paper
R&D technologies anti-PRKAA2 antibody was used to carry out western blot analysis and ChIP assays in order to investigate the mechanism for AMP-activated protein kinase regulating cellular responses to metabolic stress. more
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 to the paper
Santa Cruz Biotechnology anti-the catalytic D subunit of PKA antibody C-20 was used in human fibrosarcoma HT1080 cells and in western blot to study the role for tyrosine phosphorylation in full-scale activation of the eIF2alpha RNA-dependent protein kinase. more
total:15
Amino acid-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor are mediated by a phospholipase C/inositol 1,4,5-trisphosphate-independent pathway that requires G12, Rho, filamin-A, and the actin cytoskeleton. 2005 to the paper
Santa Cruz Biotechnology protein kinase C mu (C-20) antibody was used in western blot to study amino acid-stimulated Ca2+ oscillations through a phospholipase c/inositol 1, 4, 5-trisphosphate-independent pathway. more
total:9
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Cayman Chemicals anti-mPGES-1 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:6
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 to the paper
Abcam anti-PDIA1 antibody was used to perform western blot in order to study the role of non-directed activity-based protein profiling plays in the identification of enzymes that are either predominantly or exclusively labeled in living cells. more
total:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Neomarkers PTEN antibody was used to perform immunohistochemistry in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:2
Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid. 2007 to the paper
Osaka Bioscience Institute rabbit polyclonal anti-human L-PGDS (1:1,000 dilution) and anti-mouse L-PGDS (1:4,000 dilution) antibodies were used in immunohistochemistry to demonstrate lipocalin-type prostaglandin D synthase/beta-trace as a major amyloid beta-chaperone in human cerebrospinal fluid. more
total:5
High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance. 2010 to the paper
Thermo Fisher anti-p23 antibody was used for performing immunoblotting and immunohistochemistry in order to study the effect of high levels of Hsp90 cochaperone p23 on tumor progression and prognosis in breast cancer. more
total:12
Cyclooxygenase-2 is involved in the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma induced by tumor necrosis factor-alpha. 2009 to the paper
Santa Cruz anti-COX-1 antibody was used to perform western blot and immunohistochemistry in order to show that the cyclooxygenase-2 can leads to the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma. more
total:54
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 to the paper
Santa Cruz Biotechnology anti-COX-2 antibody was used for western blot in order to investigate the role of mPGES-1 in the regulation of tumour growth, invasion, and metastasis. more
total:17
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 to the paper
BD Biosciences mouse anti-RAN antibody was used to perform western blot in order to investigate the role of PVRL4 in tumor progression. more
total:14
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 to the paper
Santa Cruz Biotechnology polyclonal RXRs antibody was used to perform western blot in order to clarify that retinoic acid could inhibit CYP4F11 expression in human keratinocyte-derived HaCaT cells by multiple signaling pathways including RXR and JNK pathways. more
total:3
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents Sec23 antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
total:11
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 to the paper
Santa Cruz mouse anti-SHIP1 was used to perform western blot in order to show that IRAK-1 blockade is important for tolerance of human DCs induced by TLR2 and TLR4 stimulation. more
total:1
The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3. 2007 to the paper
Dr. D. Keppler (German Cancer Research Center) human OATP1B1 antibody was used in western blot to investigate the potential role of macrolides on macrolide-induced drug interactions.
total:1
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 to the paper
Dr.Bruno Stieger rabbit anti-Oatp2 antibody was used in western blot to stduy the role of radixin in maintaining apical canalicular membrane structure and function in rat hepatocytes.
total:1
The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3. 2007 to the paper
Dr. D. Keppler (German Cancer Research Center) human OATP1B3 antibody was used in western blot to investigate the potential role of macrolides on macrolide-induced drug interactions.
total:11
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 to the paper
Affinity Bioreagents anti-SMRT antibody was used to perform western blot in order to show that IRF5 mediates the transcriptional induction of proinflammatory cytokine expression in conjunction with HATs and HDACs. more
total:70
Sp1 and KLF15 regulate basal transcription of the human LRP5 gene. 2010 to the paper
Santa Cruz anti-Sp1 antibody was used to perform ChIP assay in order to study the regulatory function of Sp1 and KLF15 on basal transcription of the human LRP5 gene. more
total:1
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. 2007 to the paper
Oncogene Research Products SphK1 antibody was used in western blot to study the role of lipid phosphate phosphatase (LPP) 1 and sphingosine kinase1 (SphK1) in converting exogenous S1P to intracellular S1P.
total:1
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. 2007 to the paper
Oncogene Research Products SphK2 antibody was used in western blot to study the role of lipid phosphate phosphatase (LPP) 1 and sphingosine kinase1 (SphK1) in converting exogenous S1P to intracellular S1P.
total:3
Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology. 2009 to the paper
Abnova rabbit anti-SPT1 antibody was used to perform western blot in order to study the cellular localization of SPT1 and its functions in cell morphology. more
total:1
SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter. 2008 to the paper
Abgent anti-SPTLC2 antibody was used to perform western blot in order to study the interaction of ABCA1 and SPTLC1.
total:11
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Novus rabbit polyclonal anti-SR-B1 antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism. more
total:12
The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors. 2009 to the paper
Affinity BioReagents anti-SRC1 antibody was used in immunoprecipitation in order to investigate the cooperation between thyroid hormone receptor beta2 and p160 coactivator PAS-B through multiple contact surfaces. more
total:3
Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. 2005 to the paper
Santa Cruz Biotechnology anti-SREBP2 antibody was used in western blot to study the effect of liver X receptor alpha on SREBP1c-mediated Abcd2 expression more
total:1
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-SCAP antibody was used to carry out western blot analysis in order to investigate the role for intronic miRNA miR-33 in the regulation of cholesterol metabolism.
total:11
Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. 2009 to the paper
NeoMarkers monoclonal SREBP-1 antibody was used in western blot in order to study the mechanism by which the activation of Wnt/beta-catenin signaling in skeletal muscle cells can improve insulin sensitivity. more
total:2
Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver. 2006 to the paper
Pan-Vera polyclonal rabbit anti-human SULT2A1 antibody was used in western blot to study the different expression pattern of hepatic SULT1A1, SULT1E1, and SULT2A1. more
total:26
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 to the paper
Cell Sciences B-A38 (Syndecan-1) antibody was used in western blot in order to demonstrate that heparanase can promote expression of syndecan-1 in the nucleus. more
total:3
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. 2009 to the paper
Abcam anti-TBXAS1 antibody was used to perform western blot in order to study the novel BRAF fusion gene in 7q34 duplication of pediatric low-grade astrocytomas detected by high density SNP-based genotype array analysis. more
total:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 to the paper
Mercury mouse anti-2, 2, 7-trimethylguanosine (TMG)antibody was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing.
total:2
Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis. 2008 to the paper
EMD Chemicals anti-TRB3 antibody was used to perform western blot in order to study the response of the mTORC1 signaling after the inhibition of protein synthesis. more
total:2
Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities. 2009 to the paper
Santa Cruz Biotechnology anti-TrxR1 antibody was used in western blot in order to show that adiponectin haploinsufficiency can promote mammary tumorigenesis through inhibition of PTEN activity and activation of PI3K/Akt signalling pathway. more
total:3
An intronic locus control region plays an essential role in the establishment of an autonomous hepatic chromatin domain for the human vitamin D-binding protein gene. 2007 to the paper
Cocalico Biologicals rabbit polyclonal anti-hDBP antibody was used in radial immunodiffusion (RID) assay to study the role of an intronic locus control region in the establishment of an autonomous hepatic chromatin domain for the human vitamin D-binding protein gene. more