Metabolism of amino acids and derivatives
gene
reagent
sample publication
sample review
3 hydroxyisobutyrate dehydrogenase
3-hydroxyisobutyrate dehydrogenase
total:1
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 to the paper
ViroStat anti-NS5a antibody was used to perform western blot in order to study the role of non-directed activity-based protein profiling plays in the identification of enzymes that are either predominantly or exclusively labeled in living cells.
ACADSB
acyl-CoA dehydrogenase short/branched chain
ACAT1
acetyl-CoA acetyltransferase 1
total:2
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. 2009 to the paper
Cayman ACAT-1 antibody was used for western blot in order to investigate the role of mitochondria in endothelial cell dysfunction. more
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
ARG1
arginase 1
total:2
Hepatitis C virus targets over-expression of arginase I in hepatocarcinogenesis. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-arginase 1 antibody was used in western blot and immunohistochemistry to study the role for elevated arginase expression in HCV associated HCC more
AUH
AU RNA binding methylglutaconyl-CoA hydratase
BCAT1
branched chain amino acid transaminase 1
BCKDHA
branched chain keto acid dehydrogenase E1 subunit alpha
CPS1
carbamoyl-phosphate synthase 1
total:1
The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1. 2008 to the paper
Abcam CPS1 antibody was used in immunohistochemistry to characterize the Hep Par 1 antigen.
cystathionine beta synthase
cystathionine beta-synthase
total:1
Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70. 2010 to the paper
ABNOVA mouse anti-CBS antibody was used for western blot in order to investigate the role of Hsp70 inducing agents in the treatment of genetic diseases.
DBT
dihydrolipoamide branched chain transacylase E2
total:1
Hepatitis C virus (HCV)-induced immunoglobulin hypermutation reduces the affinity and neutralizing activities of antibodies against HCV envelope protein. 2008 to the paper
Biodesign International anti-e2 antibody was used in ELISA in order to demonstrate that HCV infection of B cells induces hypermutation of immunoglobulin gene and inactivates neutralizing and CDC activity of antibodies produced by these cells
DDC
dopa decarboxylase
total:3
Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease. 2009 to the paper
Proteintech Group anti-DDC antibody was used for western blot analysis to study therapeutic effects of RPE cell transplantation in Parkinson's disease. more
dihydropteridine reductase
quinoid dihydropteridine reductase
total:1
AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration. 2007 to the paper
Abcam mouse monoclonal DHPR antibody was used in western blot to study the role of novel dysferlin protein complex component AHNAK in skeletal muscle regeneration.
dopamine beta hydroxylase
dopamine beta-hydroxylase
total:4
Molecular mechanisms supporting a paracrine role of GABA in rat adrenal medullary cells. 2008 to the paper
Chemicon anti-chromogranin A antibody was used in immunocytochemistry in order to investigate the mechanism for the paracrine role of GABA in rat adrenal medullary (AM) cells at the molecular level. more
ETHE1
ETHE1 persulfide dioxygenase
total:1
How do human cells react to the absence of mitochondrial DNA?. 2009 to the paper
Neosystem anti-Ethe1 antibody was used for western blot to study the reaction of human cells to the absence of mitochondrial DNA.
FTCD
formimidoyltransferase cyclodeaminase
total:2
Sonic hedgehog ligand partners with caveolin-1 for intracellular transport. 2009 to the paper
Abcam anti-FTCD antibody was used to carry out western blot analysis in order to elucidate the mechanism that regulates the intracellular transportation and secretion of Caveolin-1/Shh complex. more
GCLC
glutamate-cysteine ligase catalytic subunit
glutamine synthetase
glutamate-ammonia ligase
total:6
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Chemicon/Millipore murine anti-glutamine synthetase antibody was used in western blot in order to study the function of TMX3 in eye development. more
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
histidase
histidine ammonia-lyase
total:3
TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration. 2013 to the paper
Euromedex/IGBMC anti-His antibody (HIS-1G4) was used to perform western blot in order to study the role for TRAF4, a novel phosphoinositide-binding protein in modulating tight junctions and promoting cell migration. more
IDO1
indoleamine 2,3-dioxygenase 1
total:1
T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response. 2010 to the paper
Chemicon International anti-IDO monoclonal antibody was used to perform immunohistochemistry in order to study the transcriptional features of T-cell/histiocyte-rich large B-cell lymphoma.
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
OAZ2
ornithine decarboxylase antizyme 2
ODC1
ornithine decarboxylase 1
total:2
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. 2010 to the paper
BIOMOL International anti-ODC antibody was used to carry out western blot analysis in order to investigate the precise contribution of 4E-BPs to mTORC1 signaling. more
PA200
proteasome activator subunit 4
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal regulator PA200 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
phosphoserine phosphatase
total:2
Biochemical consequences of the NOS3 Glu298Asp variation in human endothelium: altered caveolar localization and impaired response to shear. 2007 to the paper
Upstate Biotechnology phosphoserine antibody was used in western blot to demonstrate functional consequences of the Glu298Asp NOS3 variation. more
PSMA1
proteasome 20S subunit alpha 1
total:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 to the paper
Abcam C2 proteasome antibody was used in western blot in order to demonstrate that increased AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathway more
PSMA3
proteasome 20S subunit alpha 3
total:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 to the paper
Santa Cruz Biotechnology anti-Psc3 antibody was used to carry out ChIP assays in order to investigate the mechanism for how inner centromere is established and how the CPC is targeted to this site. more
PSMA4
proteasome 20S subunit alpha 4
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International mouse monoclonal anti-human 20S proteasome subunit alpha4 was used for immunohistochemistry to investigate the effect of immunoproteasome on the Multiple Sclerosis pathogenesis. more
PSMA7
proteasome 20S subunit alpha 7
total:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Enzo Life Sciences anti-alpha7 antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
PSMB1
proteasome 20S subunit beta 1
total:2
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta1 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD). more
PSMB5
proteasome 20S subunit beta 5
total:1
Transformation of the proteasome with age-related macular degeneration. 2007 to the paper
Affinity Bioreagents proteasomal subunit beta5 antibody was used in western blot in order to investigate how proteasome changes with the disease of age-related macular degeneration (AMD).
PSMB8
proteasome 20S subunit beta 8
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP7 antibody was used for immunohistochemistry to study the effect of immunoproteasome on the Multiple Sclerosis. more
PSMB9
proteasome 20S subunit beta 9
total:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International anti-LMP2 antibody was used to perform immunohistochemistry to study the role of immunoproteasome in the Multiple Sclerosis pathogenesis. more
PSMC4
proteasome 26S subunit, ATPase 4
total:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 to the paper
Cell Signaling Technology anti-phospho-Ser235/236-S6 antibody was used to perform immunocytochemistry in order to study the capacity of rapamycin to provide neuroprotection in Parkinson disease models. more
PSMC6
proteasome 26S subunit, ATPase 6
total:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 to the paper
New England BioLabs antiphospho-p44/42 MAPK antibody and p44/42 MAPK antibody (PhosphoPlus p44/42 MAPK antibody kit) was used in western blot to study the physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing RhoGEFs.
PSMD2
proteasome 26S subunit, non-ATPase 2
total:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S2 subunit antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication.
PSMD4
proteasome 26S subunit, non-ATPase 4
total:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 to the paper
Calbiochem rabbit polyclonal anti-19S proteasome S5a antibody was used to perform western blot in order to clarify that hHR23A-mediated interaction of Vpr with proteasome plays an important role in viral replication. more
PSMD9
proteasome 26S subunit, non-ATPase 9
total:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Santa Cruz anti-p27 antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
PSME1
proteasome activator subunit 1
total:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 to the paper
Affinity-Biomol International rabbit polyclonal anti-PA28alpha antibody was used for immunohistochemistry to determine the role of immunoproteasome in the Multiple Sclerosis. more
PSME2
proteasome activator subunit 2
total:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 to the paper
BIOMOL anti-proteasome activator 28 subunit beta (PA28beta) antibodoy was used to perform western blot in order to confirm the effect on the expression of proteasome-interacting proteins caused by chronic ethanol feeding.
SLC25A10
solute carrier family 25 member 10
total:4
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
Sigma-Aldrich mouse anti-DIC antibody was used in western blot (1:1,000) and immunocytochemistry (1:200) in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation. more
TPH1
tryptophan hydroxylase 1
total:2
Regional, cellular, and subcellular localization of RGS10 in rodent brain. 2005 to the paper
Sigma tryptophan hydroxylase antibody was used in immunohistochemistry to elucidate RGS10 function in the nervous system. more
tyrosine hydroxylase
total:25
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Abcam anti-Tyrosine Hydroxylase antibody (ab6211) was used to perform immunohistochemistry in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more