MHC class II antigen presentation
gene
reagent
sample publication
sample review
alpha-adaptin
adaptor related protein complex 2 subunit alpha 1
total:17
FCHo proteins are nucleators of clathrin-mediated endocytosis. 2010 to the paper
Transduction Laboratories mouse monoclonal anti-AP2A1 antibody was used to carry out western blot analysis in order to investigate the roles for FCHo1 and FCHo2 proteins in clathrin-mediated endocytosis in cell plasma membrane. more
AP1B1
adaptor related protein complex 1 subunit beta 1
total:3
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1g antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
AP1M1
adaptor related protein complex 1 subunit mu 1
AP1M2
adaptor related protein complex 1 subunit mu 2
AP1S1
adaptor related protein complex 1 subunit sigma 1
AP1S2
adaptor related protein complex 1 subunit sigma 2
AP1S3
adaptor related protein complex 1 subunit sigma 3
total:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
V. Faundez anti-sigma3-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
AP2A2
adaptor related protein complex 2 subunit alpha 2
total:5
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
Sigma anti-alpha-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. more
AP2B1
adaptor related protein complex 2 subunit beta 1
total:5
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1/2b antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
AP2M1
adaptor related protein complex 2 subunit mu 1
total:2
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. 2006 to the paper
BD Biosciences monoclonal anti-AP50 antibody was used in human HeLa cells or HUVECs and in western blot to study the role for clathrin adaptor AP2 in regulating thrombin receptor constitutive internalization and endothelial cell resensitization. more
ARF1
ADP ribosylation factor 1
total:8
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. 2007 to the paper
Affinity Bioreagents anti-Arf antibody was used to perform western blot in order to study the interaction between Arf and Poliovirus Protein 3CD and its effect on poliovirus replication. more
calnexin
total:75
A Bacteriophage tailspike domain promotes self-cleavage of a human membrane-bound transcription factor, the myelin regulatory factor MYRF. 2013 to the paper
Santa Cruz Biotechnology rabbit anti-calnexin and goat anti-calnexin antibodies were used to perform western blot and immunocytochemistry in order to investigate the mechanism of self-cleavage of MYRF. more
cathepsin B
total:14
Acid sphingomyelinase activity triggers microparticle release from glial cells. 2009 to the paper
Chemicon rabbit polyclonal anti-Cathepsin B Ab (1:200) was used in western blot in order to study the activation of acid sphingomyelinase in microparticle release from glial cells. more
cathepsin D
total:13
Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. 2009 to the paper
Santa Cruz Biotechnology primary anti-cathepsin D (H-75) was used to detect endogenous lysosomal and ER proteins by immunohistochemistry method in order to study the preferentially expressed characterization of the arylsulfatase I (ARSI) gene. more
cathepsin F
total:5
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 to the paper
Proteintech Group anti-Cathepsin F antibody was used to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas. more
cathepsin L
total:8
Anaplasma phagocytophilum increases cathepsin L activity, thereby globally influencing neutrophil function. 2008 to the paper
Calbiochem of EMD Bioscience Inc. anti-cathepsin L antibody was used in western blot to study the effect of the role for Anaplasma phagocytophilum in increasing cathepsin L activity on neutrophil function. more
CD74
CD74 molecule
total:10
Identification of potential therapeutic targets in human head & neck squamous cell carcinoma. 2009 to the paper
Santa Cruz anti-CD74 antibody was used to perform immunohistochemistry in order to find out the potential therapeutic targets of the human head and neck squamous cell carcinoma. more
CENPE
centromere protein E
total:3
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 to the paper
Abcam monoclonal anti-CENP-E antibody was used to perform immunoblotting in order to study the critical effect of Pcid2 on B cell survival through the regulation of MAD2 expression. more
Clathrin Heavy Chain
clathrin heavy chain
total:28
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 to the paper
Millipore rabbit anti-Clathrin antibody was used to perform immunoelectron microscopy in order to investigate the mechanism of Golgi-mediated protein traffic. more
CLTA
clathrin light chain A
total:5
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Sigma-Aldrich monoclonal anti-clathrin light chain antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
CTSA
cathepsin A
total:3
Expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. 2007 to the paper
Rockland anti-human PPCA antibody was used in western blot to study the expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients. more
CTSS
cathepsin S
total:4
T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. 2009 to the paper
Abcam goat polyclonal anti-cathepsin S was used to block and incubate the blots in order to suggest that T-cell activation can limits collagen maturation in the atherosclerotic plaque. more
CTSV
cathepsin V
total:2
Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification. 2006 to the paper
R&D Systems monoclonal mouse-anti-human CTSV antibody was used in immunohistochemistry to study cystatin M/E as a high affinity inhibitor of cathepsin V and cathepsin L through a reactive site that is distinct from the legumain-binding site more
DCTN2
dynactin subunit 2
total:3
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
BD Biosciences mouse anti-p50-dynamitin antibody (1:1,000) was used in immunocytochemistry in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation. more
DCTN4
dynactin subunit 4
total:1
CEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells. 2009 to the paper
Autogen Bioclear goat anti-dynactin p62 antibody was used to carry out immunofluorescence assays in order to investigate the role for CEACAM6 in restricting adenovirus infection in cancer cells.
DCTN6
dynactin subunit 6
total:1
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 to the paper
Santa Cruz anti-p27 was used to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction
DNM2
dynamin 2
total:6
Mechanisms of Chlamydia trachomatis entry into nonphagocytic cells. 2007 to the paper
BD Biosciences anti-dynamin-2 antibody was used to carry out immunofluorescence assays in order to investigate the mechanism of entry for Chlamydia trachomatis into nonphagocytic cells. more
DNM3
dynamin 3
total:2
Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef. 2007 to the paper
Affinity BioReagents anti-Dyn3 antibody was used in western blot in order to investigate the mechanism of how dynamin 2 (a binding partner of Nef) enhances the infectivity of HIV-1. more
DPB1
major histocompatibility complex, class II, DP beta 1
Dynamin
dynamin 1
total:15
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Santa Cruz Biotechnology monoclonal anti-dynamin 1 antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
DYNC1H1
dynein cytoplasmic 1 heavy chain 1
total:7
Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development. 2010 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-rat Dync1h1 antibody was used to perform western blot and immunohistochemistry in order to study the multiple functions of Dynein1 in zebrafish retinal photoreceptor development. more
DYNC2H1
dynein cytoplasmic 2 heavy chain 1
DYNC2LI1
dynein cytoplasmic 2 light intermediate chain 1
DYNLL1
dynein light chain LC8-type 1
total:3
Requirement for Nudel and dynein for assembly of the lamin B spindle matrix. 2009 to the paper
Abcam monoclonal anti-dynein antibody (74.1ab23905) was used in blocking or activating expriments to study the roles for nudel and dynein in assembly of the lamin B spindle matrix. more
gamma-adaptin
adaptor related protein complex 1 subunit gamma 1
total:15
Adaptor heat shock protein complex formation regulates trafficking of the asialoglycoprotein receptor. 2006 to the paper
Sigma mouse monoclonal anti-gamma-subunit of AP1 antibody was used in western blot to study the effect of adaptor heat shock protein complex formation on trafficking of the asialoglycoprotein receptor in HuH-7 and Trf1 human hepatoma cell lines. more
HLA-DOA
major histocompatibility complex, class II, DO alpha
HLA-DOB
major histocompatibility complex, class II, DO beta
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
total:1
Expression of CD80 and CD86 costimulatory molecules are potential markers for better survival in nasopharyngeal carcinoma. 2007 to the paper
Novocastra Laboratories anti-HLA Class II (DR) was used to perform immunohistochemistry in order to show CD80 and CD86 may be potential nasopharyngeal carcinoma markers for clinical outcome.
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
total:1
Spontaneous lupus-like syndrome in HLA-DQ2 transgenic mice with a mixed genetic background. 2010 to the paper
Becton Dickinson anti-DQ (TU39) antibody was used to perform flow cytometry in order to investigate the role of HLA-DQ2 in the pathogenesis of associated immune disorders.
HLA-DR
major histocompatibility complex, class II, DR alpha
total:22
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 to the paper
Beckman-Coulter anti-HLA DR- PC5 was used to perform flow cytometry in order to show that IRAK-1 blockade is important for tolerance of human DCs induced by TLR2 and TLR4 stimulation. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
HLA-DRB3
major histocompatibility complex, class II, DR beta 3
HLA-DRB4
major histocompatibility complex, class II, DR beta 4
HLA-DRB4
major histocompatibility complex, class II, DR beta 4
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
total:2
Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. 2008 to the paper
BD Pharmingen fluorochrome-conjugated HLA-DR antibody was used in flow cytometry in order to determine whether high LPS levels are associated with increased monocyte activation and HAD more
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
total:2
Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. 2008 to the paper
BD Pharmingen fluorochrome-conjugated HLA-DR antibody was used in flow cytometry in order to determine whether high LPS levels are associated with increased monocyte activation and HAD more
KIF23
kinesin family member 23
total:6
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Abcam anti-MKLP2 antibody was used in immunocytochemistry in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis. more
KIF2C
kinesin family member 2C
total:1
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. 2010 to the paper
Abnova mouse monoclonal anti-MCAK antibody was used to carry out immunoblotting assays in order to investigate the mechanism for Haspin-mediated histone H3 thr-3 phosphorylation regulating chromosomal passenger complex accumulation at centromeres.
KIF3A
kinesin family member 3A
total:3
Kaposi's sarcoma-associated herpesvirus ORF45 interacts with kinesin-2 transporting viral capsid-tegument complexes along microtubules. 2009 to the paper
Sigma anti-KIF3A antibodies were used to perform immunofluorescence assays in order to demonstrate that KSHV tegument protein play a crucial role in cellular transport of viral particles. more
KIF3C
kinesin family member 3C
total:1
Mobility of the von Hippel-Lindau tumour suppressor protein is regulated by kinesin-2. 2008 to the paper
BD-Biosciences KIF3C antibody was used in western blot (1:500) to investigate the role of kinesin-2 in pVHL mobility.
KIF5A
kinesin family member 5A
total:1
GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin. 2005 to the paper
Abcam anti-KIF5A (1007 1027) antibody was used in western blot to characterize GRIF-1 and OIP106 and to study their associaiton with kinesin
KIF5B
kinesin family member 5B
total:5
Depletion of kinesin 5B affects lysosomal distribution and stability and induces peri-nuclear accumulation of autophagosomes in cancer cells. 2009 to the paper
Abcam anti-KIF5B antibody ab5629 was used in western blot to study the role for kinesin 5B in cancer cells. more
KIF5B
kinesin family member 5B
total:5
Depletion of kinesin 5B affects lysosomal distribution and stability and induces peri-nuclear accumulation of autophagosomes in cancer cells. 2009 to the paper
Abcam anti-KIF5B antibody ab5629 was used in western blot to study the role for kinesin 5B in cancer cells. more
KIF5C
kinesin family member 5C
total:4
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Santa Cruz KHC antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
KIFAP3
kinesin associated protein 3
total:3
Mobility of the von Hippel-Lindau tumour suppressor protein is regulated by kinesin-2. 2008 to the paper
BD-Biosciences KAP3 antibody was used in western blot (1:500) to investigate the role of kinesin-2 in pVHL mobility. more
KLC1
kinesin light chain 1
total:2
Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3. 2009 to the paper
Chemicon anti-KLC antibody was used to perform western blot in order to show that the mutant SOD1 can sequester KAP3 and then reduce the axonal transport of choline acetyltransferase and acetylcholine release. more
OSBPL1A
oxysterol binding protein like 1A
total:1
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. 2009 to the paper
Imgenex anti-ORP1L antibody was used in immunocytochemistry in order to investigate the mechanism of the autonomous cholesterol regulation activated by adenovirus membrane protein RID-alpha.
p150Glued
dynactin subunit 1
total:9
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Santa Cruz p150Glued antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
RAB7A
RAB7A, member RAS oncogene family
total:5
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-Rab7 antibody was used to perform western blot in order to investigate the mechanism for the long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. more
RACGAP1
Rac GTPase activating protein 1
total:3
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 to the paper
Abcam anti-RacGAP antibody was used in immunocytochemistry in order to investigate the spatial and temporal coordination of subunit-Mps one binding (Mob) 1 and chromosomal passenger complex during mitosis. more
SAR1B
secretion associated Ras related GTPase 1B
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component
SEC23A
Sec23 homolog A, COPII coat complex component
total:3
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 to the paper
Affinity BioReagents Sec23 antibody was used in immunocytochemistry to study the interaction between Rab1b and GBF1 and the modulation of ARF1 dynamics and COPI association more
SEC24A
SEC24 homolog A, COPII coat complex component
SEC24B
SEC24 homolog B, COPII coat complex component
SEC24C
SEC24 homolog C, COPII coat complex component
SEC24D
SEC24 homolog D, COPII coat complex component
SEC31A
SEC31 homolog A, COPII coat complex component
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1
total:1
Study of the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma. 2007 to the paper
Santa Cruze SH3GL2 goat polyclonal antibody was used in western blot to study the SH3-study the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma.