Loss of proteins required for interphase microtubule organizationfrom the centrosome
gene
reagent
sample publication
sample review
total:5
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 to the paper
Abgent anti-CKI epsilon was used to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction more
total:5
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Santa Cruz Biotechnology anti-14-3-3epsilon antibody (1:2000) was used in western blot to study the effects of curcumin on the expression of peroxisome proliferator-activated receptor delta (PPARdelta) and related genes in HT-29 cells. more
total:3
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3gamma antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
total:19
Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2. 2009 to the paper
GeneTex mouse anti-tubulin antibody was used in western blot to study the role for the binding and interaction of ferroportin with Jak2 in hepcidin-induced internalization of ferroportin. more
total:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk1 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:1
Daughter centriole elongation is controlled by proteolysis. 2010 to the paper
BD Biosciences mouse anti-human C-Nap1 antibody was used to perform immunocytochemistry in order to study the role of proteolysis in daughter centriole elongation.
total:1
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 to the paper
Santa Cruz GFP monoclonal antibody was used in western blot in order to study the role of DGJ for enhancing GLA enzyme activity and protein expression in the atypical form of Fabry disease.
total:1
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 to the paper
Santa Cruz anti-CKI delta was used to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction
total:3
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
BD Biosciences mouse anti-p50-dynamitin antibody (1:1,000) was used in immunocytochemistry in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation. more
total:7
Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development. 2010 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-rat Dync1h1 antibody was used to perform western blot and immunohistochemistry in order to study the multiple functions of Dynein1 in zebrafish retinal photoreceptor development. more
total:3
Requirement for Nudel and dynein for assembly of the lamin B spindle matrix. 2009 to the paper
Abcam monoclonal anti-dynein antibody (74.1ab23905) was used in blocking or activating expriments to study the roles for nudel and dynein in assembly of the lamin B spindle matrix. more
total:1
Daughter centriole elongation is controlled by proteolysis. 2010 to the paper
Proteintech Group rabbit anti-human FGFR1OP antibody was used to perform immunocytochemistry in order to study the role of proteolysis in daughter centriole elongation.
total:38
Evolutionarily assembled cis-regulatory module at a human ciliopathy locus. 2012 to the paper
Sigma-Aldrich rabbit anti-gamma tubulin was used to perform immunocytochemistry in order to show that ciliogenesis was regulated by an evolutionarily assembled cis-regulatory module more
total:68
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-HSP90 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:3
Mammalian end binding proteins control persistent microtubule growth. 2009 to the paper
BD Biosciences anti-EB1 mouse monoclonal antibody was used in immunohistochemistry and western blot in order to show that persistent microtubule growth can be regulated by end binding proteins in mammal. more
total:1
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. 2009 to the paper
Proteintech Group rabbit anti-Nde1 antibody (1:1,000) was used in immunocytochemistry in order to study the hSpindly-mediated dynein functions and the role of KT dynein in spindle orientation.
total:1
A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution. 2010 to the paper
Sigma-Aldrich rabbit polyclonal anti-Odf2 antibody was used to carry out immunofluorescence assays in order to investigate the role for SEPT2 as diffusion barrier in the reguation of receptor-signaling pathways in the primary cilium.
total:1
Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. 2010 to the paper
GenTex anti-OFD1 antibody was used to perform immunofluorescence in order to investigate SDCCAG8 loss of function during heterogeneous single-gene disorders.
total:9
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 to the paper
Santa Cruz p150Glued antibody was used in western blot and immunocytochemistry in order to investigate the mechanism required for post-Golgi transport of POMC/ACTH vesicles to the plasma membrane for activity-dependent secretion more
total:6
NudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90. 2010 to the paper
Sigma anti-LIS1 antibody was uesd to perform western blot in order to study the regulation of the LIS1/dynein pathway by NudC-like protein 2 via stabilizing LIS1 with Hsp90. more
total:8
Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse. 2011 to the paper
Abcam anti-pericentrin antibody was used to perform immunocytochemistry in order to study the secretion of natural killer cell lytic granule at the immune synapse. more
total:29
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Plk1 antibody was used to perform immunoprecipitation in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate polyclonal anti-PP2A-A antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:3
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIIbeta was used in immunohistochemistry to detect the PKA subunit RIIbeta in human adrenal samples more
total:117
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Sigma mouse anti-alpha-tubulin was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:29
Overcoming mutation-based resistance to antiandrogens with rational drug design. 2013 to the paper
Santa Cruz Biotechnology anti-beta-tubulin (D-10) antibody was used to perform western blot in order to study the rational drug design for castration-resistant prostate cancer without mutation-based resistance to antiandrogens. more
total:2
Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia. 2005 to the paper
Sigma monoclonal beta IV-tubulin antibody was used in immunohistochemistry to characterize wild-type and mutant cystic fibrosis transmembrane regulator in human respiratory epithelia more