L1CAM interactions
gene
reagent
sample publication
sample review
total:5
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
BD Biosciences anti-CD166 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:17
FCHo proteins are nucleators of clathrin-mediated endocytosis. 2010 to the paper
Transduction Laboratories mouse monoclonal anti-AP2A1 antibody was used to carry out western blot analysis in order to investigate the roles for FCHo1 and FCHo2 proteins in clathrin-mediated endocytosis in cell plasma membrane. more
total:1
The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells. 2005 to the paper
Zymed Laboratories mouse anti-human ankyrin-G monoclonal antibody was used in immunohistochemistry to detect ankyrin-G in rat kidney sections and in immnocytochemistry to stain for ankyrin-G in MDCK cells.
total:5
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 to the paper
Sigma anti-alpha-Adaptin antibody was used for western blot to elucidated the interaction between Hermansky-Pudlak Syndrome protein complexes and phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. more
total:5
Death-receptor activation halts clathrin-dependent endocytosis. 2006 to the paper
BD Transduction Laboratories anti-AP1/2b antibody was used in western blot in order to investigate the effect of death-receptor activation on clathrin-dependent endocytosis. more
total:2
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. 2006 to the paper
BD Biosciences monoclonal anti-AP50 antibody was used in human HeLa cells or HUVECs and in western blot to study the role for clathrin adaptor AP2 in regulating thrombin receptor constitutive internalization and endothelial cell resensitization. more
total:85
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 2010 to the paper
Biolegend anti-CD29-FITC antibody was used to perform flow cytometry in order to study the properties induced by cell signaling by urokinase-type plasminogen activator receptor (uPAR) in breast cancer cells. more
total:10
Identification of potential therapeutic targets in human head & neck squamous cell carcinoma. 2009 to the paper
Chemicon anti-CD24 antibody was used to perform immunohistochemistry in order to find out the potential therapeutic targets of the human head and neck squamous cell carcinoma. more
total:13
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD41 was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:56
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. 2012 to the paper
eBioscience anti-CD56 eFluor780 was used to perform flow cytometry in order to show that commensal bacteria was restricted in specific sites by innate lymphoid cells more
total:2
Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. 2010 to the paper
R&D Systems goat anti-CHL1 antibody (1:500) was used for western blot in order to investigate the role of PKCdelta in the regulation of CHL1 expression in cultured astrocytes.. more
total:5
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Sigma-Aldrich monoclonal anti-clathrin light chain antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
total:1
Nav1.7 expression is increased in painful human dental pulp. 2008 to the paper
Neuromab mouse monoclonal anti-caspr (catalog #75-001, 1:500) antibody was used in immunohistochemistry to study Nav1.7 expression in painful human dental pulp
total:9
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 to the paper
Santa-Cruz Biotechnology anti-CK2 alpha antibody was used to carry out western blot analysis in order to investigate the role for NF-kB transcription factor in the interleukin-1 induced expression of C/EBP delta and APP genes. more
total:4
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 to the paper
Santa-Cruz Biotechnology anti-CK2 alpha' antibody was used to carry out western blot analysis in order to investigate the role for NF-kB transcription factor in the interleukin-1 induced expression of C/EBP delta and APP genes. more
total:2
CK2beta is expressed in endometrial carcinoma and has a role in apoptosis resistance and cell proliferation. 2009 to the paper
Santa Cruz anti-CK2B antibody was used to perform western blot and immunohistochemistry in order to show the role of CK2B in apoptosis resistance and cell proliferation in endometrial carcinoma. more
total:6
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. 2006 to the paper
Affinity BioReagents SAP97 antibody (1:3000) was used in western blot to demonstrate that dendritic A-type K+ channels regulate action potential backpropagation and the induction of specific forms of synaptic plasticity. more
total:2
Spectrin functions upstream of ankyrin in a spectrin cytoskeleton assembly pathway. 2006 to the paper
Developmental Studies Hybridoma Bank mouse anti-Dlg (discs large) antibody was used in western blot to test contributions of four specific functional sites in beta spectrin to its assembly and function. more
total:6
Mechanisms of Chlamydia trachomatis entry into nonphagocytic cells. 2007 to the paper
BD Biosciences anti-dynamin-2 antibody was used to carry out immunofluorescence assays in order to investigate the mechanism of entry for Chlamydia trachomatis into nonphagocytic cells. more
total:2
Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef. 2007 to the paper
Affinity BioReagents anti-Dyn3 antibody was used in western blot in order to investigate the mechanism of how dynamin 2 (a binding partner of Nef) enhances the infectivity of HIV-1. more
total:6
Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia. 2011 to the paper
Millipore guinea pig anti-DCX antibody(1:500)was used to perform immunocytochemistry in order to investigate the role of retinoic acid in generation of GABAergic neurons in the basal ganglia. more
total:2
Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3. 2009 to the paper
Immuno-Biological Laboratories anti-CRMP-2 antibody was used to perform western blot in order to show that the mutant SOD1 can sequester KAP3 and then reduce the axonal transport of choline acetyltransferase and acetylcholine release. more
total:15
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 to the paper
Santa Cruz Biotechnology monoclonal anti-dynamin 1 antibody was used to carry out immunohistochemistry assays in order to investigate the influence of strain variations on trafficking pathways of PrP of sheep scrapie. more
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:29
Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1. 2011 to the paper
Santa Cruz rabbit anti-ERK antibody was used to perform immunocytochemistry in order to investigate the role of the PKA/AKAP1 complex in the maintenance of mitochondrial integrity and the protection from neuronal injury. more
total:252
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Millipore anti-ERK1/2 polyclonal antibody (1:10,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediated anti-apoptotic effects. more
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:27
Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. 2012 to the paper
Cell Signaling anti-Ezrin antibody was used to perform immunoprecipitation in order to study NKCC1 modulation of glioma cell migration. more
total:17
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Biosource International anti-FGFR-1 (pYpY653/654) antibodies were used to perform western blot and ELISA analyses in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
total:25
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
Stressgen monoclonal anti-Hsc70 antibody was used to carry out western blot analysis in order to determine the atomic structure of human adenovirus. more
total:24
TGFBI expression is associated with a better response to chemotherapy in NSCLC. 2010 to the paper
Chemicon Interational anti-integrin alphavbeta3 monoclonal was used to perform flow cytometry in order to determine if this integrin influences TGFBI-mediated NSCLC cell susceptibility to chemotherapy. more
total:15
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha2 antibody (clone P1E6) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
total:30
The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis. 2008 to the paper
Chemicon monoclonal anti-alpha5 was used to perform blocking experiments in order to show that integrins could interact with CXCL4 and play a role in angiogenesis. more
total:28
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal integrin beta3 antibody (1:1000) was used in western blot in order to study the role of activated state of p42/44 and p38 in MMP-13 expression. more
total:11
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 to the paper
Chemicon monoclonal anti-integrin alpha1 antibody (clone FB12) was used in western blot to study the role of TEM5 in angiogenesis in human umbilical vein endothelial cells. more
total:5
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. 2009 to the paper
Proteintech Group anti-RLC antibody was used to perform western blot in order to study the assemble of mammalian nonmuscle myosin II in live cells. more
total:2
Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons. 2006 to the paper
Chemicon KCNQ2 antibody was used in western blot to study the role of Kv7/KCNQ/M channels in the control of cell excitability. more
total:1
Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons. 2006 to the paper
Chemicon KCNQ3 antibody was used in western blot to study the role of Kv7/KCNQ/M channels in the control of cell excitability.
total:16
Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle. 2008 to the paper
Chemicon rabbit polyclonal laminin antibody was used in immunohistochemistry in order to study the role of talin 1 in the development and function of skeletal muscle more
total:57
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Cell Signaling Technology anti-MEK1 antibody was used to perform flow cytometry and immunochemistry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:16
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. 2010 to the paper
Cell Signaling Technologies anti-phospho-MEK1/2 antibody was used to perform western blot in order to study the discrimination between the yeast and hyphal forms of C. albicans in epithelial cells via a biphasic MAPK response. more
total:10
Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane. 2009 to the paper
NeoMarkers moesin antibody was used in western blot in order to study the role of phospholipase C in rapid cytoskeletal remodeling and the role of PIP2 in hydrolysis-mediated ERM inactivation. more
total:7
Role of placenta growth factor in malignancy and evidence that an antagonistic PlGF/Flt-1 peptide inhibits the growth and metastasis of human breast cancer xenografts. 2007 to the paper
Santa Cruz Biotechnology NRP-1 antibody was used in western blot and immunohistochemistry to study the role of placenta growth factor in malignancy. more
total:20
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Santa Cruz anti-RSK-1 antibody (1:1,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediates anti-apoptotic effects. more
total:29
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Epitomics rabbit monoclonal anti-Pak1 antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
total:24
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. 2010 to the paper
Thermo Scientific monoclonal anti-PSD-95 antibody was used to carry out western blot analysis and immunofluorescence assays in order to determine the atomic structure of human adenovirus. more
total:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Millipore anti-Rac1 monoclonal antibody (1:1,000) was used to perform immunoblot in order to study the metastasis suppressed by Rho GDP dissociation inhibitor 2 (RhoGDI2) through Rho GTPases. more
total:4
Participation of ezrin in bacterial uptake by trophoblast giant cells. 2009 to the paper
EPITOMICS anti-radixin antibody was used to perform western blot in order to study the roles of ezrin in bacterial uptake by trophoblast giant cells. more
total:9
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 to the paper
Cell Signaling anti-phosphorylated p90RSK antibody was used to perform western blot in order to study the important role of GRK4 in D3 receptor's signaling in human proximal tubule cells. more
total:9
Mitogen-activated protein kinase-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection. 2009 to the paper
Santa Cruz anti-RSK2 antibody was used to perform western blot in order to study the role of RSK2 in the cellular antiviral response. more
total:3
Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation. 2009 to the paper
Santa Cruz Biotechnology MSK1 antibody was used in western blot in order to study the role of MSK1 in NF-kB activation and inflammatory diseases more
total:4
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. 2006 to the paper
Chemicon NaV1.1 antibody was used in western blot and immunohistochemistry to study the role of educed sodium currents in GABAergic inhibitory interneurons in Scn1a+/- heterozygotes in SMEI. more
total:3
A role for myosin VI in the localization of axonal proteins. 2011 to the paper
Neuromab anti-Nav1.2 antibody was used to perform immunocytochemistry in order to study the functions of myosin VI in the localization of axonal more
total:2
Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration. 2005 to the paper
USBiological antibody which recognizes sodium channel beta 2 subunit was used in western blot to study the regulation of cell adhesion and migration by presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-Subunit. more
total:1
Voltage-gated sodium channels in taste bud cells. 2009 to the paper
Chemicon rabbit polyclonal antibody against SCN3A was used in immunohistochemistry to investigate the role of SCN2A, SCN3A, and SCN9A in the regulation of taste cell action potentials.
total:1
Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome. 2006 to the paper
Santa Cruz Biotechnology anti-hNav1.5 antibody was used in immunohistochemistry diluted 1:500 to demonstrate that both caveolin-3 and hNav1.5 colocalize at the plasma membrane of human cardiomyocytes.
total:1
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. 2006 to the paper
Chemicon anti-SCN8a antibody was used in western blot and immunohistochemistry to study the role of educed sodium currents in GABAergic inhibitory interneurons in Scn1a+/- heterozygotes in SMEI.
total:2
Voltage-gated sodium channels in taste bud cells. 2009 to the paper
Chemicon rabbit polyclonal antibody against SCN9A was used in immunohistochemistry to investigate the role of SCN2A, SCN3A, and SCN9A in the regulation of taste cell action potentials. more
total:1
Study of the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma. 2007 to the paper
Santa Cruze SH3GL2 goat polyclonal antibody was used in western blot to study the SH3-study the SH3-domain GRB2-like 2 gene expression in laryngeal carcinoma.
total:6
Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease. 2005 to the paper
Chemicon anti-spectrin antibody was used in western blot in order to investigate the molecular mechanism of beta-amyloid induced significant decrease of dynamin1. more
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:8
Human T-cell leukemia virus type 1 oncoprotein tax represses ZNF268 expression through the cAMP-responsive element-binding protein/activating transcription factor pathway. 2008 to the paper
Epitomics anti-Tax monoclonal antibody was used to perform EMSA in order to show that ZNF268 expression can be inhibited by HTLV-1 Tax. more