Ion channel transport
gene
reagent
sample publication
sample review
ASIC1
acid sensing ion channel subunit 1
total:2
Proton sensitivity Ca2+ permeability and molecular basis of acid-sensing ion channels expressed in glabrous and hairy skin afferents. 2006 to the paper
Chemicon International ASIC antibody was used in immunocytochemistry to demonstrate that ASIC- as well as non-ASIC expressing nociceptors have highly distinct cutaneous targets. more
ASIC3
acid sensing ion channel subunit 3
total:2
ASIC3 in muscle mediates mechanical, but not heat, hyperalgesia associated with muscle inflammation. 2007 to the paper
Chemicon ASIC3 antibody was used in immunohistochemistry and elisa to study the role of ASIC3 in the development of cutaneous mechanical hyperalgesia induced by muscle inflammation. more
ASIC5
acid sensing ion channel subunit family member 5
ATP10A
ATPase phospholipid transporting 10A (putative)
ATP10B
ATPase phospholipid transporting 10B (putative)
ATP10D
ATPase phospholipid transporting 10D (putative)
ATP11B
ATPase phospholipid transporting 11B (putative)
ATP1A1
ATPase Na+/K+ transporting subunit alpha 1
total:23
Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry. 2009 to the paper
Abcam anti-Na+/K+ ATPase (ab7671) antibody was used to perform western blot in order to study the altered expression levels of metastasis-related plasma membrane proteins of human breast cancer cells. more
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
total:4
Recombinant addition of N-glycosylation sites to the basolateral Na,K-ATPase beta1 subunit results in its clustering in caveolae and apical sorting in HGT-1 cells. 2005 to the paper
Upstate polyclonal antibody against the Na, K-ATPase 2 subunit was used in immunocytochemistry to study the role of Na, K-ATPase beta1 subunit in unusual apical location of the Na, K-ATPase in HGT-1 cells. more
ATP1AL1
ATPase H+/K+ transporting non-gastric alpha2 subunit
ATP1B3
ATPase Na+/K+ transporting subunit beta 3
total:5
Control of chemokine gradients by the retinal pigment epithelium. 2008 to the paper
Abcam Na, K-ATPase antibody was used in immunocytochemistry in order to examine the physiological responses of human fetal retinal pigment epithelia (hfRPE) after polarized activation of proinflammatory cytokine receptors in vitro more
ATP2A1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
total:4
Increased nitration of sarcoplasmic reticulum Ca2+-ATPase in human heart failure. 2005 to the paper
Affinity Bioreagents mouse monoclonal anti-SERCA2a antibody was used in western blot to study the role of SERCA2a nitration in heart failure in tissue from normal and failing human hearts. more
ATP2A3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
total:2
Regulation of the nitric oxide pathway genes by tetrahydrofurandiols: microarray analysis of MCF-7 human breast cancer cells. 2008 to the paper
Santa Cruz Biotechnologies ATP2A3 antibody was used in western blot in order to study the role of THF-diols in the regulation of the nitric oxide pathway genes more
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
total:5
Plasma membrane Ca2+-ATPase isoforms in frog crista ampullaris: identification of PMCA1 and PMCA2 specific splice variants. 2007 to the paper
Affinity BioReagents mouse monoclonal PMCA1 (1:200 1:600) antibody was used in immunohistochemistry to determine the identity and distribution of PMCA isoforms in frog crista ampullaris. more
ATP2B2
ATPase plasma membrane Ca2+ transporting 2
total:3
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Affinity BioReagents anti-PMCA2 antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
ATP2B3
ATPase plasma membrane Ca2+ transporting 3
total:2
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Affinity BioReagents anti-PMCA3 antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
ATP2B4
ATPase plasma membrane Ca2+ transporting 4
total:3
Topology of the yeast fatty acid transport protein Fat1p: mechanistic implications for functional domains on the cytosolic surface of the plasma membrane. 2007 to the paper
Dr. Guenther Daum mouse anti-Pma1p antibody was used in western blot to define the role of Fat1p in the transport of exogenous fatty acids. more
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
ATP2C2
ATPase secretory pathway Ca2+ transporting 2
ATP4A
ATPase H+/K+ transporting subunit alpha
total:2
Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells. 2005 to the paper
Calbiochem anti-H, K-ATPase antibody was used in western blot in order to investigate the mechanism of achlorhydria caused by ezrin knockdown in vivo. more
ATP4B
ATPase H+/K+ transporting subunit beta
total:3
Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells. 2005 to the paper
Affinity BioReagents anti-beta-subunit H, K-ATPase antibody was used in western blot in order to investigate the mechanism of achlorhydria caused by ezrin knockdown in vivo. more
ATP7A
ATPase copper transporting alpha
total:5
Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells. 2008 to the paper
Santa Cruz Biotechnology goat anti-ATP7A antibody was used in immunocytochemistry in order to assess the relevance of sub cellular localization of the copper efflux transporters ATP7A and ATP7B for acquired cisplatin resistance in vitro. more
ATP7B
ATPase copper transporting beta
total:4
Elevated glutathione levels confer cellular sensitization to cisplatin toxicity by up-regulation of copper transporter hCtr1. 2008 to the paper
Orbigen rabbit polyclonal ATP7B antibody (1:500) was used in western blot in order to investigate the cause-effect relationships between elevated GSH and CDDP sensitivity more
ATP8A2
ATPase phospholipid transporting 8A2
total:4
T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20. 2008 to the paper
Cell Signaling Technology IB phosphorylated at Ser32 and/or Ser36 antibody was used in western blot to demonstrate that T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20. more
ATP8B3
ATPase phospholipid transporting 8B3
ATP8B4
ATPase phospholipid transporting 8B4 (putative)
ATP9A
ATPase phospholipid transporting 9A (putative)
ATP9B
ATPase phospholipid transporting 9B (putative)
CLCN4
chloride voltage-gated channel 4
CLCNKA
chloride voltage-gated channel Ka
FXYD1
FXYD domain containing ion transport regulator 1
FXYD2
FXYD domain containing ion transport regulator 2
FXYD3
FXYD domain containing ion transport regulator 3
FXYD4
FXYD domain containing ion transport regulator 4
FXYD6
FXYD domain containing ion transport regulator 6
FXYD7
FXYD domain containing ion transport regulator 7
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
total:3
Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X. 2009 to the paper
Chemicon Inc.monoclonal anti-human alpha1 antibody (BD24) was used in western blot in order to study that GABAA receptor alpha1 subunit mutation, 975delC, S326fs328X induce the activation of NMD and ERAD which contribute to epileptogenesis. more
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
total:2
GABA(A) receptor downregulation in brains of subjects with autism. 2009 to the paper
Alpha Diagnostic International anti-GABAA receptor alpha 2 (GABRA2) antibody was used in western blot in order to demonstrate that GABAA receptors are reduced in three brain regions of subjects with autism more
GABRA3
gamma-aminobutyric acid type A receptor subunit alpha3
total:1
GABA(A) receptor downregulation in brains of subjects with autism. 2009 to the paper
Alpha Diagnostic International GABAA receptor alpha 3 (GABRA3) antibody was used in western blot in order to demonstrate that GABAA receptors are reduced in three brain regions of subjects with autism
GABRB3
gamma-aminobutyric acid type A receptor subunit beta3
total:2
GABA(A) receptor downregulation in brains of subjects with autism. 2009 to the paper
Alpha Diagnostic International anti-GABAA receptor beta 3 (GABRB3) antibody was used in western blot in order to demonstrate that GABAA receptors are reduced in three brain regions of subjects with autism more
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
total:2
Cellular distribution and subcellular localization of molecular components of vesicular transmitter release in horizontal cells of rabbit retina. 2005 to the paper
Dr.D. Pow gamma-aminobutyric acid antibody was used in immunohistochemistry (1:200) to study the distribution and subcellular localization of molecular components of vesicular transmitter release in horizontal cells of rabbit retina. more
GABRR3
gamma-aminobutyric acid type A receptor subunit rho3 (gene/pseudogene)
NALCN
sodium leak channel, non-selective
OSTM1
osteoclastogenesis associated transmembrane protein 1
Raf-1
Raf-1 proto-oncogene, serine/threonine kinase
total:46
MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. 2010 to the paper
Santa Cruz Biotechnology anti-RAF1 antibody was used to perform western blot in order to study the role of microRNA-7 in tongue squamous cell carcinoma cells. more
RPS27A
ribosomal protein S27a
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
RyR1
ryanodine receptor 1
total:7
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 to the paper
Affinity Bioreagents anti-RyR antibody was used for western blot in order to investigate the role of CaMKII in the regulation of pressure overload-induced cardiac hypertrophy to heart failure in mice. more
RYR2
ryanodine receptor 2
total:6
Increased susceptibility to isoproterenol-induced cardiac hypertrophy and impaired weight gain in mice lacking the histidine-rich calcium-binding protein. 2006 to the paper
Affinity Bioreagents anti-ryanodine receptor 2 antibody was used in western blot in order to investigate the function of histidine-rich calcium-binding protein (HRCBP) associated with calcium handling in vivo. more
SCNN1D
sodium channel epithelial 1 subunit delta
total:2
Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration. 2009 to the paper
Santa Cruz ENaC antibody was used to perform western blot in order to study its role in glioblastoma cell migration and whole cell current. more
SCNN1G
sodium channel epithelial 1 subunit gamma
total:1
Delta-subunit confers novel biophysical features to alpha beta gamma-human epithelial sodium channel (ENaC) via a physical interaction. 2006 to the paper
Affinity Bioreagents anti-gammaENaC polyclonal antibody was used in western blot to detect gammaENaC in human H441 cells
SERCA2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
total:10
Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2. 2007 to the paper
Affinity BioReagents mouse anti-SERCA-2a antibody was used in western blot (1:1,000) to study the role of polycystin-2 in regulating ryanodine receptor-dependent calcium signaling. more
SGK1
serum/glucocorticoid regulated kinase 1
total:5
Hsp90 regulates the phosphorylation and activity of serum- and glucocorticoid-regulated kinase-1. 2008 to the paper
Santa Cruz Biotechnology anti-phospho-Ser-78 antibody was used in western blot in order to investigate the SGK-1 (serum- and glucocorticoid-regulated kinase-1) activity and its phosphoinositide 3-kinase (PI3K) dependent phosphorylation are highly as more
SLC9B1
solute carrier family 9 member B1
SLC9B2
solute carrier family 9 member B2
SLC9C1
solute carrier family 9 member C1
SLC9C2
solute carrier family 9 member C2 (putative)
triadin
total:1
Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins. 2006 to the paper
Affinity BioReagents triadin antibody was used in western blot to study the expression of RyR1 and its interacting triadic proteins in TRPC3 knockdown mouse myotube cell culture
TRPC1
transient receptor potential cation channel subfamily C member 1
total:5
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells. 2005 to the paper
Alomone Labs anti-TRPC1 antibody was used in western blot to study the role of endogenous TRPC6 channels in Ca2+ signal generation. more
TRPC3
transient receptor potential cation channel subfamily C member 3
total:6
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC3 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
TRPC4
transient receptor potential cation channel subfamily C member 4
total:7
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC4 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
TRPC4AP
transient receptor potential cation channel subfamily C member 4 associated protein
TRPC5
transient receptor potential cation channel subfamily C member 5
total:4
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC5 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
TRPC6
transient receptor potential cation channel subfamily C member 6
total:7
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 to the paper
Santa Cruz Biotechnology TRPC6 goat polyclonal antibody was used in western blot and immunohistochemistry to study the expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. more
TRPC7
transient receptor potential cation channel subfamily C member 7
total:1
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells. 2005 to the paper
Santa Cruz anti-TRPC7 antibody was used in western blot to study the role of endogenous TRPC6 channels in Ca2+ signal generation.
TRPM1
transient receptor potential cation channel subfamily M member 1
TRPM2
transient receptor potential cation channel subfamily M member 2
total:1
Regulation of the transient receptor potential channel TRPM2 by the Ca2+ sensor calmodulin. 2006 to the paper
Bethyl Laboratories anti-TRPM2-N and anti-TRPM2-C antibodies were used in human HEK 293T cells, and which were used in western blot and western blot, immunoprecipitation, to study the role for Ca2+ sensor calmodulin in regulating transient receptor potential channel TRPM2.
TRPM3
transient receptor potential cation channel subfamily M member 3
TRPM4
transient receptor potential cation channel subfamily M member 4
total:1
De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury. 2009 to the paper
Santa Cruz Biotechnology Trpm4 antibody (1:100) was used for western blot in order to investigate the role of Trpm4 in the regulation of secondary hemorrhage in spinal cord injury.
TRPM5
transient receptor potential cation channel subfamily M member 5
TRPM6
transient receptor potential cation channel subfamily M member 6
TRPM7
transient receptor potential cation channel subfamily M member 7
total:1
Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation. 2007 to the paper
Abgent anti-TRPM7 was used to perform immunohistochemistry in order to study TRPM7-like's roles in cell proliferation in human head and neck turmor cells.
TRPV1
transient receptor potential cation channel subfamily V member 1
total:4
Cellular localization of kinin B1 receptor in the spinal cord of streptozotocin-diabetic rats with a fluorescent [Nalpha-Bodipy]-des-Arg9-bradykinin. 2009 to the paper
Chemicon mouse anti-TRPV1 antibody was used for western blot in order to investigate the role of B1R in the regulation of oxidative stress. more
TRPV4
transient receptor potential cation channel subfamily V member 4
TRPV5
transient receptor potential cation channel subfamily V member 5
UBC
ubiquitin C
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
ubiquitin
ubiquitin B
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
UNC79
unc-79 homolog, NALCN channel complex subunit
UNC80
unc-80 homolog, NALCN channel complex subunit
WWP1
WW domain containing E3 ubiquitin protein ligase 1
total:1
Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. 2006 to the paper
Santa Cruz anti-WWP1 antibody was used in immunoprecipitation to study regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.