Interleukin and interleukin receptor
gene
reagent
sample publication
sample review
total:5
Intracellular IL-1alpha-binding proteins contribute to biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts. 2006 to the paper
R & D Systems monoclonal anti-human IL-1alpha antibody was used in human SSc fibroblasts and in immunocytochemistry, immunoprecipitation to study the effect of intracellular IL-1alpha-binding proteins on biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts. more
total:30
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-1-beta mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:5
Control of chemokine gradients by the retinal pigment epithelium. 2008 to the paper
Abcam IL-1R1 antibody was used in western blot in order to examine the physiological responses of human fetal retinal pigment epithelia (hfRPE) after polarized activation of proinflammatory cytokine receptors in vitro more
total:2
Stable inhibition of interleukin 1 receptor type II in Ishikawa cells augments secretion of matrix metalloproteinases: possible role in endometriosis pathophysiology. 2007 to the paper
R&D Systems polyclonal goat anti-human IL1R2 antibody was used in western blot and immunocytochemistry to evaluate the role of IL1R2 deficiency in endometriosis pathophysiology. more
total:2
Stable inhibition of interleukin 1 receptor type II in Ishikawa cells augments secretion of matrix metalloproteinases: possible role in endometriosis pathophysiology. 2007 to the paper
R&D Systems polyclonal goat anti-human IL1RAcP antibody was used in western blot and immunocytochemistry to evaluate the role of IL1R2 deficiency in endometriosis pathophysiology. more
total:3
IL-33 mediates inflammatory responses in human lung tissue cells. 2010 to the paper
R&D Systems anti-ST2/IL1R4 antibody was used in western blot to study the role of IL-33 in inflammatory responses in human lung tissue cells. more
total:1
Beta-(1-->3)-D-glucan modulates DNA binding of nuclear factors kappaB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratio. 2006 to the paper
R&D Systems IL-1RA ELISA ket was used to study inflammatory response induced by glucan
total:17
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
BD Pharmingen anti-IL-2 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:49
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. 2009 to the paper
eBioscience anti-CD25 antibody was used in flow cytometry in order to investigate the role of dendritic cells in the regulation of spontaneous fatal autoimmunity. more
total:5
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
BD Biosciences PE anti-CD122 monoclonal antibody was used to perform flow cytometry to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:5
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. 2008 to the paper
BD Bioscience CD132 antibody was used to perform flow cytometry in order to identify that IL-13 is an effector cytokine and IL-4 is an immunoregulatory cytokine. more
total:4
Covering a broad dynamic range: information processing at the erythropoietin receptor. 2010 to the paper
R&D Systems anti-IL3 antibody was used to carry out immunoprecipitation assay and western blot analysis in order to determine the receptor property of erythropoietin receptor during receptor signaling activation. more
total:12
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD123 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:19
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
R&D Systems anti-IL-4 was used in 5ug/ml to perform cell stimulation in order to show that blood-brain barrier integrity and CNS immune quiescence were promoted by sonic hedgehog pathway. more
total:43
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-6 mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:10
Intracellular signaling mechanisms and activities of human herpesvirus 8 interleukin-6. 2009 to the paper
Santa Cruz Biotechnology anti-gp80 antibody was used in western blot in order to study the role of vIL-6 in the growth and survival of cells latently infected with HHV-8. more
total:12
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway. 2010 to the paper
Santa Cruz Biotechnology anti-GP130 polyclonal antibody was used to perform immunohistochemistry in order to study the modulation of IL11 expression by PROK1 via PROKR1 and the calcineurin/NFAT signalling pathway. more
total:3
The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors. 2009 to the paper
BD Pharmingen anti-IL7-R antibody was used in flow cytometry in order to investigate the role of MOZ in the regulation of the proliferation of hematopoietic precursors. more
total:6
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Immunotech anti-CDw127 was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
total:46
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
R&D systems anti-IL8 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:7
Short-term heat exposure inhibits inflammation by abrogating recruitment of and nuclear factor-{kappa}B activation in neutrophils exposed to chemotactic cytokines. 2008 to the paper
Santa Cruz IL-8-receptor antibody was used in western blot in order to test the hypothesis that exposure of mice to fever-like temperatures abrogates neutrophil recruitment and NF-kappaB activation in a mouse model of skin inflammation more
total:9
The role of the chemokines MCP-1, GRO-alpha, IL-8 and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques. 2008 to the paper
R&D Systems CXCR2 IgG2a antbody was used to inhibit cell adhesion in order to study the role of the chemokines MCP-1, GRO-alpha, IL-8, and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques more
total:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
R&D Systems anti-IL-10 antibody was used to perform ELISA in order to study how gut microbiota regulate immunesystem. more
total:1
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-10R2 mAb was used to perform western blot in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26.
total:5
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway. 2010 to the paper
R&D Systems anti-IL11 monoclonal antibody was used to perform ELISA and immunohistochemistry in order to study the modulation of IL11 expression by PROK1 via PROKR1 and the calcineurin/NFAT signalling pathway. more
total:4
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway. 2010 to the paper
Santa Cruz Biotechnology anti-IL-11RA antibody was used to perform immunohistochemistry in order to study the modulation of IL11 expression by PROK1 via PROKR1 and the calcineurin/NFAT signalling pathway. more
total:9
Importance of stromal determinants in the generation of dendritic and natural killer cells in the human spleen. 2005 to the paper
R&D Systems anti-IL-12 p70 antibody was used in flow cytometry and anti-IL-12 antibody (which is in a ELISA kit) was in ELISA to study the role for stromal determinants in the generation of dendritic and natural killer cells in the human spleen fibroblasts. more
total:2
Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. 2005 to the paper
BioSource Europe SA anti-IL-12 (p40) antibody (which was in ELISA kit) was used in venous blood samples from human and in ELISA to study the association of serum levels of some proinflammatory cytokines in vivo and their correlation with severity of psoriasis. more
total:10
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
BD Pharmingen anti-IL-13 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:3
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. 2008 to the paper
R&D Systems anti-IL-13Ralpha1 antibody was used for flow cytometry to elucidated the role of IL-4 and IL-13 in regulates relative cytokine sensitivity. more
total:4
Expression of glioma-associated antigens in pediatric brain stem and non-brain stem gliomas. 2008 to the paper
R&D goat anti-human IL-13Ralpha2 polyclonal antibody (15 ug/ml) was used in immunohistochemistry in order to investigate the protein expression of three glioma-associated antigens (GAAs) in pediatric brain stem glioma (BSG) and non-brain stem glioma (NBSG) cases more
total:7
Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo. 2009 to the paper
R&D Systems anti-human IL-15R antibody was used to perform enzyme-linked immunosorbent assays in order to investigate the relationship between IL-15R and specific immune response. more
total:19
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
eBioscience anti-IL-17A mAb was used to perform flow cytometry and cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:3
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. 2011 to the paper
R&D Systems PE-anti-human IL-17RA was used to perform flow cytometry in order to show that IL-17 immunodeficiency could lead to CMCD. more
total:1
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. 2011 to the paper
R&D Systems APC-anti-human IL-17RC was used to perform flow cytometry in order to show that IL-17 immunodeficiency could lead to CMCD.
total:7
Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. 2005 to the paper
BioSource Europe SA anti-IL-18 antibody (which was in ELISA kit) was used in venous blood samples from human and in ELISA to study the association of serum levels of some proinflammatory cytokines in vivo and their correlation with severity of psoriasis. more
total:2
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. 2009 to the paper
R&D Systems anti-IL-18R-PE antibody was used to carry out flow cytometry analysis in order to investigate the mechanism for IL-33 in promoting allergic inflammation. more
total:2
Expression and suppressive effects of interleukin-19 on vascular smooth muscle cell pathophysiology and development of intimal hyperplasia. 2008 to the paper
R&D Systems anti-IL19 anibody was used in western blot in order to demonstrate that IL-19 can be induced by inflammatory cytokines and inflammatory stimuli more
total:1
The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells. 2009 to the paper
EBioscience antibody against IL-21R was used for flow cytometry in order to demonstrate IL-6 promotes antibody production through increased IL-21 production.
total:6
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems APC-labeled anti-IL-22mAb was used to perform flow cytometry in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:1
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. 2011 to the paper
R&D Systems APC-anti-human IL-22RA1 was used to perform flow cytometry in order to show that IL-17 immunodeficiency could lead to CMCD.
total:1
Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation. 2009 to the paper
R&D Systems anti-IL-22BP was used for neutralization in order to study the function of CD161+ cells that can be activated by IL-23 and mediate destructive tissue inflammation.
total:4
Combinatorial synergy induced by adenoviral-mediated mda-7 and Herceptin in Her-2+ breast cancer cells. 2006 to the paper
S Chada (Introgen Therapeutics) MDA-7 antibody was used in western blot to demonstrate that combination of Ad-mda7 with Herceptin may be a novel therapy for breast cancer. more
total:1
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems mouse anti-IL-26 mAb was used to perform cell stimulation, biotin-labeled goat anti-IL-26 polyclonal antibody was used to perform western blot,ELISA and immunohistochemistry in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26.
total:1
IL-32-dependent effects of IL-1beta on endothelial cell functions. 2009 to the paper
R&D Systems anti-human IL-32 was used in western blot in order to study the role for IL-32 in the effect of IL-1 on endothelial cell functions.