Interleukin-7 signaling
gene
reagent
sample publication
sample review
hepatocyte growth factor
total:9
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 to the paper
R&D Systems monoclonal anti-human HGF antibody (MoAb) was used in blocking or activating expriments to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. more
IL-7
interleukin 7
total:3
The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors. 2009 to the paper
BD Pharmingen anti-IL7-R antibody was used in flow cytometry in order to investigate the role of MOZ in the regulation of the proliferation of hematopoietic precursors. more
IL-7
interleukin 7
total:3
The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors. 2009 to the paper
BD Pharmingen anti-IL7-R antibody was used in flow cytometry in order to investigate the role of MOZ in the regulation of the proliferation of hematopoietic precursors. more
IL2RG
interleukin 2 receptor subunit gamma
total:5
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. 2008 to the paper
BD Bioscience CD132 antibody was used to perform flow cytometry in order to identify that IL-13 is an effector cytokine and IL-4 is an immunoregulatory cytokine. more
IL7R
interleukin 7 receptor
total:6
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Immunotech anti-CDw127 was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
Jak1
Janus kinase 1
total:22
Identification of human thioredoxin as a novel IFN-gamma-induced factor: mechanism of induction and its role in cytokine production. 2008 to the paper
Santa Cruz anti-Jak1 and anti-p-Jak1 were used to perform western blot in order to show that thioredoxin is an IFN-gamma-induced factor and plays a role for cytokine production. more
Jak3
Janus kinase 3
total:9
The JAK kinase inhibitor CP-690,550 suppresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation. 2008 to the paper
Upstate Biotechnology anti-JAK3(04-011) antibody was used to perform western blot in order to study the JAK kinase inhibitor reduces the growth of human polycythemia vera cells. more
p85
phosphoinositide-3-kinase regulatory subunit 1
total:43
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Upstate anti-p85 pAb was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
PIK3R2
phosphoinositide-3-kinase regulatory subunit 2
total:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Millipore polyclonal anti-human p85 antibody was used to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
STAT5
signal transducer and activator of transcription 5A
total:51
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. 2010 to the paper
Santa Cruz Biotechnology anti-STAT5 antibody was used to perform immunoprecipitation in order to study the interaction between MUC1-C and STAT1 pathway in poor prognosis human breast cancers. more
STAT5B
signal transducer and activator of transcription 5B
total:23
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 2009 to the paper
Upstate Biotech-Millipore anti-P-STAT5B (Y699) antibody was used in western blot in order to characterize the role of ERBB4 mutations in melanoma. more