Interleukin-6 signaling
gene
reagent
sample publication
sample review
total:13
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 to the paper
Cell Signaling Technology anti-pY774-c-Cbl antibody was used to carry out western blot analysis in order to investigate the mechanism for Lyn kinase regulating imatinib sensitivity in chronic myelogenous leukemia cells. more
total:12
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway. 2010 to the paper
Santa Cruz Biotechnology anti-GP130 polyclonal antibody was used to perform immunohistochemistry in order to study the modulation of IL11 expression by PROK1 via PROKR1 and the calcineurin/NFAT signalling pathway. more
total:43
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 to the paper
R&D Systems anti-IL-6 mAb was used to perform cell stimulation in order to study the secretion of proinflammatory cytokine and generation of Th17 cell induced by IL-26. more
total:10
Intracellular signaling mechanisms and activities of human herpesvirus 8 interleukin-6. 2009 to the paper
Santa Cruz Biotechnology anti-gp80 antibody was used in western blot in order to study the role of vIL-6 in the growth and survival of cells latently infected with HHV-8. more
total:22
Identification of human thioredoxin as a novel IFN-gamma-induced factor: mechanism of induction and its role in cytokine production. 2008 to the paper
Santa Cruz anti-Jak1 and anti-p-Jak1 were used to perform western blot in order to show that thioredoxin is an IFN-gamma-induced factor and plays a role for cytokine production. more
total:34
Covering a broad dynamic range: information processing at the erythropoietin receptor. 2010 to the paper
Upstate anti-JAK2 antibody was used to carry out immunoprecipitation assay and western blot analysis in order to determine the receptor property of erythropoietin receptor during receptor signaling activation. more
total:34
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-Shp2 antibody was used to perform western blot in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
total:10
Unique early gene expression patterns in human adult-to-adult living donor liver grafts compared to deceased donor grafts. 2009 to the paper
Santa Cruz Biotech SOCS3 antibody was used in immunohistochemistry to study the distinctive differences at the molecular level between deceased donor (DD) and living donor (LD) liver grafts more
total:84
T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response. 2010 to the paper
Santa Cruz Biotechnology anti-STAT1 polyclonal antibody was used to perform immunohistochemistry in order to study the transcriptional features of T-cell/histiocyte-rich large B-cell lymphoma. more
total:120
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset. 2010 to the paper
Santa Cruz Biotechnology anti-STAT3 monoclonal antibody was used to perform western blot to study the role of tyrosine kinase Tec in the generation of CD44highCD62L- Th17 subset. more
total:13
Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. 2008 to the paper
Santa Cruz Biotechnology anti-Tyk2 and anti-p-Tyk2 polyclonal antibodies were used to perform immunoprecipitation and western blot assays in order to demonstrate that Z3 is a novel specific inhibitor that can suppresses Jak2-mediated pathologic cell growth. more