Integrin alphaIIb beta3 signaling
gene
reagent
sample publication
sample review
Akt
AKT serine/threonine kinase 1
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
APBB1IP
amyloid beta precursor protein binding family B member 1 interacting protein
CD41
integrin subunit alpha 2b
total:13
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Biolegend anti-CD41 was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
Crk
CRK proto-oncogene, adaptor protein
total:14
Focal adhesion components are essential for mammalian cell cytokinesis. 2008 to the paper
BD Transduction Laboratories CrkI/II antibody was used to perform western blot in order to study the function of focal adhesion components in mammalian cell cytokinesis. more
CSK
C-terminal Src kinase
total:7
Leukocyte-associated Ig-like receptor-1 has SH2 domain-containing phosphatase-independent function and recruits C-terminal Src kinase. 2006 to the paper
Santa Cruz anti-Csk antibody was used in immnoprecipitation to study the role of leukocyte-associated Ig-like receptor-1. more
FAK
protein tyrosine kinase 2
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
FGB
fibrinogen beta chain
total:1
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 to the paper
Behring rabbit anti-fibrinogen antibody was used to carry out immunofluorescence assays in order to investigate the association for increased expression of urokinase plasminogen activator and megakaryocyte differentiation in Quebec platelet disorder.
fibrinogen
fibrinogen alpha chain
total:4
Biomarkers for ragwort poisoning in horses: identification of protein targets. 2008 to the paper
Affiland rabbit (polyclonal) anti-(equine) fibrinogen antibody was used in western blot in order to investigate whether pyrrole toxins induce specific modifications of equine blood proteins that are detectable by proteomic methods more
fibronectin
fibronectin 1
total:39
Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors. 2010 to the paper
Sigma Aldrich anti-fibronectin antibody was used to perform immunocytochemistry and western blot in order to study the mechanism by which Angiotensin-(1-7) inhibited CAF growth and reduced tumour fibrosis in orthotopic breast tumors. more
Grb2
growth factor receptor bound protein 2
total:36
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal against Ron antibody was used in western blot in order to demostrate the expression of PAX 5 and the regulation for c-Met transcription in small cell lung cancer. more
integrin beta3
integrin subunit beta 3
total:28
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 to the paper
Santa Cruz Biotechnology mouse monoclonal integrin beta3 antibody (1:1000) was used in western blot in order to study the role of activated state of p42/44 and p38 in MMP-13 expression. more
p130Cas
BCAR1 scaffold protein, Cas family member
total:9
Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling. 2010 to the paper
Santa Cruz Biotechnology Inc anti-p130CAS antibody was used for immunoblotting in order to illustrate the mechanism of silencing SCARA5 in HCC tumorigenesis and metastasis. more
RAPGEF3
Rap guanine nucleotide exchange factor 3
total:3
Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels. 2007 to the paper
Santa Cruz Biotechnology anti-EPAC antibody was used in western blot to determine whether the PDE4 sequestered by DISC1 is released after cAMP elevation. more
RAPGEF4
Rap guanine nucleotide exchange factor 4
total:4
An autism-associated variant of Epac2 reveals a role for Ras/Epac2 signaling in controlling basal dendrite maintenance in mice. 2012 to the paper
Santa Cruz anti-Epac2 monoclonal antibody was used to perform coimmunoprecipitations in order to study the role of Epac2 coupleing with Ras signaling in controlling basal dendrite maintenance. more
Shc
SHC adaptor protein 1
total:20
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Cell Signalling anti-ShcA and anti-phospho-ShcA (Tyr239/240) antibodies were used to perform western blot in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
Sos
SOS Ras/Rac guanine nucleotide exchange factor 1
total:11
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 to the paper
Santa Cruz rabbit Sos-1 antibody was used in western blot to study the role of Abi-1 in morphogenesis and synapse formation. more
Src
SRC proto-oncogene, non-receptor tyrosine kinase
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
Syk
spleen associated tyrosine kinase
total:12
Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk.. 2008 to the paper
Santa Cruz Biotech anti-Syk antibody was used to perform western blot in order to study the interaction between NS5A and Syk. more
Talin
talin 1
total:10
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Serotec anti-talin antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more
von Willebrand factor
total:32
Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells. 2009 to the paper
Serotec sheep anti-VWF was used to test von Willebrand factor (VWF) in order to research Rab27a and MyRIP's regulation to the amount and multimeric state of VWF released from endothelial cells. more