Innate Immune System
gene
reagent
sample publication
sample review
total:9
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 to the paper
Santa Cruz 14-3-3beta antibody was used in western blot at dilution of 1/1000 in order to identify 14-3-3 beta and zeta isoforms and proteolytic fragments of alpha-spectrin as proteins released from degenerating neurons more
total:5
Targeting A20 decreases glioma stem cell survival and tumor growth. 2010 to the paper
Abcam anti-A20 antibody was used for western blot and flow cytometry to study the function of A20 in glioma stem cell survival and tumor growth. more
total:1
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 to the paper
Santa Cruz goat Abi antibody (1:2000) was used in western blot to study the role of Abi-1 in morphogenesis and synapse formation.
total:35
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 to the paper
Calbiochem c-Abl antibody (1:1,000) was used for western blot in order to investigate the role of c-Abl tyrosine kinase in the regulation of cardiac growth and development. more
total:4
Mechanisms of Chlamydia trachomatis entry into nonphagocytic cells. 2007 to the paper
Chemicon anti-Arp2 antibody was used to carry out immunofluorescence assays in order to investigate the mechanism of entry for Chlamydia trachomatis into nonphagocytic cells. more
total:2
Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase. 2005 to the paper
FabGennix isoform-specific anti-adenylate cyclase antibody was used in western blot to study the effedt of interferon-gamma on adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia. more
total:2
Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. 2007 to the paper
Santa Cruz Biotechnology AC2 antibody was used in western blot to demonstrate stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. more
total:3
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 to the paper
Santa Cruz anti-adenylyl cyclase III antibody was used in immunocytochemistry in order to elucidate the isoforms of plasma membrane calcium pumps (PMCAs) are not identical in different places. more
total:3
Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. 2007 to the paper
Santa Cruz Biotechnology anti-adenylate cyclase antibody was used in western blot to study the role of PDE3B and its interaction with PKB for regulation of specific cAMP pools and signalling pathways by insulin. more
total:4
Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA. 2010 to the paper
Millipore anti-Ago2 antibody was used to carry out immunoprecipitation assays in order to investigate the role for Herpesvirus saimiri Noncoding RNA HSURs in the regulation of host cell microRNAs. more
total:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-phospho-Ser473Akt polyclonal antibody was used to perform western blot to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival. more
total:4
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. 2011 to the paper
Cell Signaling Technology anti-phospho-PRAS40 was used to perform western blot in order to show that how growth factor signaling is inhibited by mTOR through mTOR-regulated phosphoproteome. more
total:4
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. 2008 to the paper
Millipore anti-Akt3 was used to perform western blot in order to show that PTEN-null tumors is promoted to autophagy and more sensitive to lysosomotropic agents after Akt inhibition. more
total:81
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Chemicon anti-APP was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
total:2
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 to the paper
Santa Cruz anti-Arp2/3 antibody was used to perform immunohistochemistry in order to show that the Hela /-CaD is involved with the migration of endothelial cells/endothelial progenitor cells in human neoplasms. more
total:6
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology murine monoclonal anti-ATF-1 antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:20
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB2 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:2
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Cell Signaling anti-ATG12 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:3
Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. 2010 to the paper
Sigma rabbit polyclonal anti-Atg5 antibody (1:1000) was used in western blot in order to study the regulation of autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. more
total:5
Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression. 2008 to the paper
Dako anti-B2m was used to perform immunohistochemistry in order to study the presence of specific populations of tumor infiltrating lymphocytes in diagnostic primary melanoma biopsies are associated with outcome in clinically stage II melanoma patients. more
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Cell Signaling Technology, anti-BAD monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:130
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Santa Cruz anti-Bcl-2 antibody (C-2, sc-7382, 1:500) was used to perform western blot in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
total:85
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. 2008 to the paper
Santa Cruz Biotechnology mouse anti-Bcl-XL monoclonal antibody was used to perform western blot in order to study the function of the natural product honokiol. more
total:6
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-Bcl10 monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:149
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 to the paper
Santa Cruz anti-beta-actin was used to perform western blot in order to show that DNA metabolism and genomic integrity were maintained by MMS19. more
total:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 to the paper
Millipore anti-beta-catenin was used to perform ChIP assay in order to show that telomerase was regulated by Wnt/beta-catenin signaling. more
total:2
ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx. 2005 to the paper
R&D Systems goat anti-human BTC ectodomain (Asp32 Tyr111) antibody was used in immunoprecipitation, biotinylated goat anti-human BTC ectodomain in western blot and mouse anti-human BTC ectodomain antibody in ELISA to study the role for ADAM10 to mediate ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate (APMA) and extracellular calcium influx. more
total:41
Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-c-Fos antibody was used to carry out immunohistochemistry assays in order to investigate the effect of lossing BDNF receptor in different neurons on control of cocaine reward. more
total:15
Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination. 2011 to the paper
Alexis anti-cIAP1 was used to perform western blot in order to show that autoubiquitination could be promoted by conformational change of cIAP1 induced by antagonists. more
total:11
Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies. 2009 to the paper
Santa Cruz Biotechnology anti-cIAP-2 antibody was used for western blot in order to investigate the role of ARIA in the regulation of endothelial apoptosis and angiogenesis. more
total:100
Plasma membrane contributes to the formation of pre-autophagosomal structures. 2010 to the paper
Abcam anti-AP1-A1 antibody was used to perform western blot in order to study the role of plasma membrane in the formation of preautophagosomal structures. more
total:42
Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. 2012 to the paper
NeoMarkers mouse anti-human CD117 monoclonal antibody was used to perform immunohistochemistry in order to analyze the cellular origin of adult functional blood vessels. more
total:1
Analysis of binding sites in human C-reactive protein for Fc{gamma}RI, Fc{gamma}RIIA, and C1q by site-directed mutagenesis. 2005 to the paper
Quidel mouse monoclonal C1q antibody was used in ELISA to study various binding sites in human C-reactive protein
total:12
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. 2011 to the paper
AbD serotec goat-anti-Human-C3 was used to perform ELISA in order to show that HIV glycan coat could be recognized by PGT antibody to neutralize HIV. more
total:2
Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cells. 2009 to the paper
Chemicon C4 monoclonal antibody was used in western blot to study the role of TLS DNA polymerases eta and kappa in the regulation of naturally occurring DNA structures in human cancer cells. more
total:1
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. 2005 to the paper
Quidel mouse monoclonal antibody against C5b-9 was used in ELISA to study the association of the extracellular matrix and inflammation
total:2
Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. 2010 to the paper
S.Piddelsden anti C9neo antibody (1:2000) was used to perform immunohistochemistry in order to study the function of the astrocytic antigen aquaporin 4 (AQP-4) in inflammatory demyelinating diseases. more
total:3
Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation. 2005 to the paper
Transduction Laboratories monoclonal anti-CaMKIV antibody was used in western blot and immunocytochemistry to study the presence of CaMKIV in mammalian sperm and its role in the regulation of human sperm motility. more
total:2
The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association. 2008 to the paper
Prosci anti-CARD11 antibody was used in western blot in order to demonstrate that CARD11 can recruit signaling cofactors independently of one another in a signal-inducible manner. more
total:4
The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells. 2009 to the paper
MBL monoclonal anti-caspase-4 antibody (4B9) was used in western blot to study the effect of E693deletemutation in amyloid precursor protein on intracellular accumulation of amyloid beta oligomers and its role in causing endoplasmic reticulum stress-induced apoptosis in cultured cells more
total:7
Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI. 2008 to the paper
Santa Cruz Caspase-1 antibody was used in western blot in order to analyze changes in a subproteome of ~800 proteins in the promyelocytic leukemia cell line HL-60 upon treatment with the proteasome inhibitor PSI more
total:9
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. 2006 to the paper
R & D Systems anti-caspase-10 antibody was used in human THP-1 cells and in western blot to study the roles for the interaction of the B30.2 domain of pyrin, the familial mediterranean fever protein with caspase-1 in IL-1 production. more
total:9
Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI. 2008 to the paper
Santa Cruz Caspase-2 antibody was used in western blot in order to analyze changes in a subproteome of ~800 proteins in the promyelocytic leukemia cell line HL-60 upon treatment with the proteasome inhibitor PSI more
total:73
Detachment of esophageal carcinoma cells from extracellular matrix causes relocalization of death receptor 5 and apoptosis. 2009 to the paper
R&D systems anti-casp8 antibody was used to carry out western blot analysis in order to investigate the mechanism of DR5 relocalization and its effect on cell apoptosis during adhesion to detachment of EC9706 cells. more
total:75
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. 2008 to the paper
Santa Cruz Biotechnology anti-caspase-9 antibody was used to perform immunocytochemistry in order to study the protective autophagy involved in trail resistance of apoptosis-defective tumor cells. more
total:14
Acid sphingomyelinase activity triggers microparticle release from glial cells. 2009 to the paper
Chemicon rabbit polyclonal anti-Cathepsin B Ab (1:200) was used in western blot in order to study the activation of acid sphingomyelinase in microparticle release from glial cells. more
total:8
Anaplasma phagocytophilum increases cathepsin L activity, thereby globally influencing neutrophil function. 2008 to the paper
Calbiochem of EMD Bioscience Inc. anti-cathepsin L antibody was used in western blot to study the effect of the role for Anaplasma phagocytophilum in increasing cathepsin L activity on neutrophil function. more
total:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 to the paper
Santa Cruz Biotechnology anti-CBP antbody was used in western blot in order to demonstrate that an HDAC inhibitor induces apoptosis through the FoxO1 acetylation-Bim pathway more
total:9
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 to the paper
R&D systems anti-CCR2 antibody (1:100) was used to perform immunohistochemistry in order to study the effect of MCP1 and CD40 ligation on VEGF production. more
total:5
CC chemokine receptor 6 expression by B lymphocytes is essential for the development of isolated lymphoid follicles. 2007 to the paper
R&D Systems rat anti-mouse CCR6 antibody was used in flow cytometry to study the role for CCR6 in the development of isolated lymphoid follicles (ILFs). more
total:46
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Beckman-coulter PE-conjugated anti-CD11b was used to perform flow cytometry in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
total:80
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
AbDSerotec PE-Cy5-conjugated anti-CD14 antibody was used to perform flow cytometry in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
total:42
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
AbDSerotec PE-Cy5-conjugated anti-CD16 antibody was used to perform flow cytometry in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
total:23
CBFbeta is critical for AML1-ETO and TEL-AML1 activity. 2009 to the paper
eBioscience allophycocyanin (APC), phycoerythrin (PE), or PerCPcy5.5 conjugated anti Mac-1 (clone M1/70) antibody was used in flow cytometry in order to determine whether CBFbeta is required for AML1-ETO and TEL-AML1 activity more
total:62
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Becton Dickinson anti-CD19 PE was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
total:68
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD3 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
total:25
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. 2012 to the paper
eBioscience anti-human CD28 was used to perform blocking or activating experiments in order to show that cancer cell depended on glycine for rapid proliferation. more
total:9
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 to the paper
Upstate anti-IgG antibody was used to perform RNA immunoprecipitation in order to analyze histone methylation at transcription start sites in human-specific prefrontal neurons of brain. more
total:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD36 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:48
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBioscience anti-CD3 antibody was used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:118
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. 2011 to the paper
Beckman coulter anti-CD4 PC5 was used to perform flow cytometry in order to show that human long-term engrafting HSCs could be isolated with CD49f as a marker. more
total:8
CD147/EMMPRIN acts as a functional entry receptor for measles virus on epithelial cells. 2010 to the paper
Hycult-Biotechnologies anti-CD46 mouse monoclonal antibody was used to perform western blot and flow cytometry in order to study the function of CD147/EMMPRIN as a receptor for measles virus on epithelial cells. more
total:14
The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor alpha expression in the synovium. 2008 to the paper
Serotec monoclonal anti-CD55 antibody (67) was used in immunohistochemistry to determine whether the heterogeneous clinical response to tumour necrosis factor (TNF) alpha blocking therapy in rheumatoid arthritis (RA) can be predicted by TNFalpha expression in the synovium before initiation of treatment. more
total:10
Activity after site-directed mutagenesis of CD59 on complement-mediated cytolysis. 2008 to the paper
Santa Cruz Biotechnology goat anti-human CD59 polyclonal antibody(Catalog #, sc-7077) was used to perform Enzyme-linked immunosorbent assays in order to demonstrate that residue W40 site of CD59 is important to its anti-complement activity. more
total:15
PPAR? controls Dectin-1 expression required for host antifungal defense against Candida albicans. 2010 to the paper
Serotec anti-F4/80 antibody was used in flow cytometry in order to investigate the role of PPARgamma in the regulation dectin-1 expression and host antifungal defense. more
total:24
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Beckman anti-CD80 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 to the paper
Beckman anti-CD86 antibody was used to perform flow cytometry in order to study how gut microbiota regulate immunesystem. more
total:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 to the paper
Santa Cruz anti-human Cdk1 antibody was used to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase. more
total:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 to the paper
Santa Cruz Biotechnology anti-Cdc42 antibody was used in western blot to reveal the effect of slit2 on eosinophil and neutrophil during lung inflammation. more
total:1
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-Adipsin antibody was used to carry out western blot analysis in order to identify the binding sites of PPAR Gramma and RXR in a genome wide manner during adipogenesis.
total:8
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Sigma-Aldrich polyclonal anti-cofilin and anti-phospho-cofilin antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
total:2
Mesenchymal stem cell-mediated functional tooth regeneration in swine. 2006 to the paper
Pharmingen/BD Bioscience R-PE conjugated monoclonal anti-human CD35 antibody was used in human mesenchymal stem cell and in flow cytometry to study the role for mesenchymal stem cell in tooth regeneration in swine. more
total:58
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-CREB1 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:14
Focal adhesion components are essential for mammalian cell cytokinesis. 2008 to the paper
BD Transduction Laboratories CrkI/II antibody was used to perform western blot in order to study the function of focal adhesion components in mammalian cell cytokinesis. more
total:1
Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes. 2005 to the paper
Alpha Diagnostic International rabbit anti-human C-terminal modulator protein (CTMP) antibody was used in western blot to study the effect of the interaction between histone deacetylase inhibitors and protein phosphatase 1 complexes on Akt in human U87MG cells.
total:4
T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. 2009 to the paper
Abcam goat polyclonal anti-cathepsin S was used to block and incubate the blots in order to suggest that T-cell activation can limits collagen maturation in the atherosclerotic plaque. more
total:2
Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification. 2006 to the paper
R&D Systems monoclonal mouse-anti-human CTSV antibody was used in immunohistochemistry to study cystatin M/E as a high affinity inhibitor of cathepsin V and cathepsin L through a reactive site that is distinct from the legumain-binding site more
total:1
Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling. 2008 to the paper
ABGENT anti-RIG-I antibody was used to perform western blot in order to study the cellular signaling elicited by human metapneumovirus in airway epithelial cells.
total:1
Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling. 2008 to the paper
ABGENT anti-RIG-I antibody was used to perform western blot in order to study the cellular signaling elicited by human metapneumovirus in airway epithelial cells.
total:1
Role of Toll-like receptor 4 and human defensin 5 in primary endocervical epithelial cells. 2010 to the paper
ADL rabbit anti-HD5 antibody was used to perform western blot in order to study the immune defence role of TLR4 and HD5 in primary endocervical epithelial cells.
total:2
Nuclear hBD-1 accumulation in malignant salivary gland tumours. 2008 to the paper
Biologo hBD-1 antibody was used in immunohistochemistry in order to characterize proteins involved in cell cycle control more
total:2
Nuclear hBD-1 accumulation in malignant salivary gland tumours. 2008 to the paper
Gentaur hBD-3 antibody was used in immunohistochemistry in order to characterize proteins involved in cell cycle control more
total:12
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Millipore anti-DNA-PKcs antibody was used to perform western blot and immunofluorescence in order to study IRF-3-dependent innate immunity more
total:3
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. 2009 to the paper
Santa Cruz anti-DUSP4 antibody was used for western blot in order to investigate the role of BRAF in the regulation of RAF-MEK signaling pathway. more
total:6
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-MKP3 antibody was used to perform flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:9
Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-EGF antibody was used in immunohistochemistry to study whether the expression of tyrosine kinase growth factor receptors is constant or varies between and within individual colon cancer neoplasms. more
total:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 to the paper
Santacruz Biotechnology anti-EGFR antibody was used to perform western blot in order to study how ING1a induces senescence. more
total:13
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 to the paper
Santa Cruz monoclonal anti-p-ELK1 was used to perform ChIP assay and western blot in order to show that immediate early gene expression is disrupted by MED23 mutation and results in intellectual disability. more
total:18
Activation of Stat3 by heregulin/ErbB-2 through the co-option of progesterone receptor signaling drives breast cancer growth. 2009 to the paper
Neomarkers ErbB-3 mouse monoclonal antibody was used to carry out antibody blocking assays in order to investigate the signal cross talk between ErbB2 and PR receptor and the effect on breast cancer growth. more
total:20
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 2009 to the paper
Santa Cruz Biotechnology anti-ERBB4 antibody was used in immunoprecipitation and western blot in order to characterize the role of ERBB4 mutations in melanoma. more
total:1
Human corneal epithelial cell proliferation by epiregulin and its cross-induction by other EGF family members. 2007 to the paper
R & D Systems anti-epiregulin antibody was used in immunohistochemistry to study human corneal epithelial cell proliferation by epiregulin and its cross-induction by other EGF family members
total:252
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Millipore anti-ERK1/2 polyclonal antibody (1:10,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediated anti-apoptotic effects. more
total:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Santa Cruz Biotechnology anti-ERK1/2 antibody and anti-p-ERK1/2 antibody were used to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:2
Transcriptional regulation of tissue-specific genes by the ERK5 mitogen-activated protein kinase. 2005 to the paper
Biosource anti-phosphoERK5 antibody was used in western blot to study tissue-specific transcriptional regulation by ERK5 more
total:12
Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. 2010 to the paper
AbD Serotec mouse monoclonal anti-human FH was used to perform flow cytometry in order to show that function of factor H is defective in patients with systemic sclerosis and sclerodermatous GVHD. more
total:19
Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis. 2008 to the paper
Cell Signaling Technology anti-FADD antibody was used to perform western blot in order to assess the effect of Rk1 on cell viability and telomerase activity. more
total:101
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 to the paper
Santa Cruz Biotechnology anti-Fak antibody (1:1000) was used to carry out immunofluorescence assays in order to study whether c-Src kinase contributes the progression from atypical lobular hyperplasia, and lobular carcinoma in situ to invasive lobular carcinoma. more
total:8
Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis. 2011 to the paper
eBioscience biotin-anti-Fc epsilon RI alpha antibody was used to perform flow cytometry in order to study the role of eosinophils in metabolic homeostasis. more
total:3
High-affinity IgE receptor-beta chain expression in human mast cells. 2008 to the paper
Upstate Biotechnology rabbit anti-FcepsilonRI-gamma polyclonal antibody was used in western blot in order to clarify beta-chain protein expression in human mast cells more
total:20
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. 2009 to the paper
Chemicon rabbit polyclonal anti-FGF2 antibody was used in western blot to study the role for endothelial-derived FGF2 in the progression of pulmonary hypertension in humans and rodents. more
total:2
HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. 2006 to the paper
R&D Systems goat polyclonal anti-human FGF-1 antibody was used in ELISA to study the HSulf-2 which selectively mobilizes heparin-bound growth factors and chemokines. more
total:2
Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. 2008 to the paper
R&D Systems FGF9 antibody was used in immunohistochemistry at 5 ug/ml in order to study the role of androgen receptor null cells in prostate cancer bone metastases treatment more
total:17
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Biosource International anti-FGFR-1 (pYpY653/654) antibodies were used to perform western blot and ELISA analyses in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
total:9
Endothelial function of von Hippel-Lindau tumor suppressor gene: control of fibroblast growth factor receptor signaling. 2008 to the paper
Santa Cruz rabbit polyclonal anti-FGFR2 was used to perform western blot in order to show that VHL tumor supppressor gene has endothelial function through fibroblast growth factor receptor signaling. more
total:7
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Santa Cruz mouse anti-FGFR3 was used at 1:1000 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:5
Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-FGFR4 antibody was used to carry out western blot analysis in order to investigate whether FGFR4 plays a role in promoting the progression of hepatocellular carcinoma. more
total:20
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 to the paper
Santa Cruz anti-FKHR antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters. more
total:18
CAMKII and calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16.. 2013 to the paper
Cell Signaling rabbit anti-mFOXO3(phospho-S252)/hFOXO3(phospho-S253) antibody was used to perform western blot in order to investigate the regulatory effect of calcineurin and CAMKII on the lifespan of Caenorhabditis elegans. more
total:4
Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits. 2008 to the paper
Chemicon monoclonal mouse anti-O4 antibody (clone:81, Cat:MAB345) was used in immunohistochemistry to study what happens in the cerebellar cortex of peripuberal rabbits by using endogenous and exogenously-administered cell proliferation antigens in association with a cohort of typical markers for neurogenesis. more
total:6
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 to the paper
Santa Cruz rabbit anti-FRS was used at 1:250 to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients. more
total:19
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 to the paper
Santa Cruz Biotechnology rabbit anti-FYN antibody was used for immunoprecipitation in order to study the effect of DC ehrlichiae on cell signaling, transcriptional regulation, and vesicle trafficking. more
total:9
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Upstate Biotechnology polyclonal anti-Gab1 antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
total:6
The Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivo. 2009 to the paper
Upstate anti-Gab2 polyclonal antibody was used in western blot in order to demonstrate that Lyn can inhibit osteoclast formation. more
total:16
Genes associated with the tumour microenvironment are differentially expressed in cured versus primary chemotherapy-refractory diffuse large B-cell lymphoma. 2008 to the paper
Novocastra anti-Galectin-3 antibody was used to perform immunohistochemistry in order to study the diversity of gene expression profiles in tumours. more
total:3
T cell receptor-induced activation of phospholipase C-gamma1 depends on a sequence-independent function of the P-I region of SLP-76. 2005 to the paper
Upstate Cell Signaling Solutions anti-Gads polyclonal antibody was used in western blot to demonstrate T-cell receptor-induced activation of phospholipase C-gamma1 by a sequence-independent function of the P-I region of SLP-76. more
total:36
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal against Ron antibody was used in western blot in order to demostrate the expression of PAX 5 and the regulation for c-Met transcription in small cell lung cancer. more
total:9
Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2. 2008 to the paper
Santa Cruz Biotechnolog GRK2 polyclonal antibody was used to immunodetect myocardial levels in order to study the uncoupling of myocardial beta-Adrenergic receptor signaling during coronary artery bypass grafting: The Role of GRK2 more
total:10
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. 2011 to the paper
Stressgen anti-GRP94 was used in 1/1000 to perform western blot in order to show that regulatory subunit of protein phosphatase 1 could be blocked by small molecule selectively. more
total:23
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Santa Cruz Biotechnology anti-GSK3 alpha antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
total:79
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 to the paper
Santa Cruz Biotechnology anti-GSK3 beta antibody was used to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy. more
total:3
Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules. 2009 to the paper
Santa Cruz goat anti-GW182 antibody (1:100) was used to perform immunofluorescence in order to prove that the association of AKAP350A and CCAR1 with RNA stress granules is microtubule dependent. more
total:26
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
Calbiochem/Merck anti-H-Ras antibody was used to perform western blot in order to study the role of spatial coupling of cells' catabolic and anabolic machinery in facilitating the synthesis of secretory proteins. more
total:6
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
R&D Systems goat anti-HB-EGF polyclonal antibody was used in immunoprecipitation and immunohistochemistry (1:50) in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:11
Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis. 2010 to the paper
Biologo polyclonal rabbit anti-human HBD-2 was used to perform immunohistochemistry in dilution 1:100 and ELISA in dilution 1:1000 in order to show that the levels of human neutrophil peptides 1-3 secretion is inhibited by tumor necrosis factor and norepinephrine in mixed synovial tissue cultures from osteoarthritis and rheumatoid arthritis patients. more
total:9
Regulation of p73 by Hck through kinase-dependent and independent mechanisms. 2007 to the paper
Santa Cruz rabbit polyclonal anti-Hck was used to perform western blot and immunoprecipitation and immunocytochemistry in order to show the mechanisms through which Hck regulates p73 function more
total:69
Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. 2008 to the paper
Zymed Laboratories anti-c-erbB-2 antibody was used in immunohistochemistry to investigate the relationship between amphiregulin expression and liver metastases of colorectal cancer. more
total:1
An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases. 2009 to the paper
Santa Cruz anti-Cyclin E antibody was used to perform immunoprecipitation in order to identify new components of the CRL family of E3 ligases and elaborate new connections between the CRL and CSN complexes.
total:1
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 to the paper
PharMingen anti-HLA-B antibody was used in flow cytometry immunophenotyping to study the function of fibromodulin which serves as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL) to enable the expansion of specific CD8+ autologous T lymphocytes
total:12
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Serotec FITC-conjugated anti-MHC-I was used to perform flow cytometry in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:7
Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection. 2009 to the paper
Invitrogen Purified goat IgG was used as the isotypic controls in order to identify the MHC I molecule (HLA-C) as an attachment factor in facilitating HCoV-HKU1 spike (S) mediated infection. more
total:7
Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection. 2009 to the paper
Invitrogen Purified goat IgG was used as the isotypic controls in order to identify the MHC I molecule (HLA-C) as an attachment factor in facilitating HCoV-HKU1 spike (S) mediated infection. more
total:10
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Abcam anti-HMGB1 antibody was used to perform western blot in order to study the role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
total:68
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 to the paper
Santa Cruz Biotechnology anti-HSP90 was used to perform western blot in order to show that cell abscission mediated by Aurora B was regulated by ESCRT-III. more
total:8
Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. 2010 to the paper
Millipore anti-H3S28P antibody was used in western blot in order to investigate the mechanism of how the embryonic stem cells chromatin structure change was regulated by condensin complexes during mitotic progression. more
total:1
IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells. 2005 to the paper
Santa Cruz Biotechnology anti-IFI16 antibody was used in western blot to study that IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells.
total:2
Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling. 2008 to the paper
IMGENEX anti-MDA-5 antibody was used to perform western blot in order to study the cellular signaling elicited by human metapneumovirus in airway epithelial cells. more
total:2
Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling. 2008 to the paper
IMGENEX anti-MDA-5 antibody was used to perform western blot in order to study the cellular signaling elicited by human metapneumovirus in airway epithelial cells. more
total:11
The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide.. 2010 to the paper
PBL Laboratories anti-IFNalpha antibody was used in flow cytometry in order to investigate the role of VP35 Protein of Ebola Virus in the regulation of dendritic cell maturation induced by virus and lipopolysaccharide. more
total:9
Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria. 2009 to the paper
Biosource ELISA kit for IFN-beta was used to measure IFN-beta level in order to study the effect of gC1qR on RIG-I and MDA5-dependent antiviral response at mitochondria. more
total:117
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 to the paper
Santa Cruz anti-I-kappa B alpha antibody was used to perform western blot in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells. more
total:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-IKKalpha monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:36
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Millipore anti-IKK2 antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
total:21
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 to the paper
Santa Cruz Biotechnology anti-NEMO antibody was used to perform western blot in order to investigate the structural basis for human IKK2 activation. more
total:10
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 to the paper
Santa Cruz mouse anti-IRAK-1 was used to perform western blot in order to show that IRAK-1 blockade is important for tolerance of human DCs induced by TLR2 and TLR4 stimulation. more
total:2
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 to the paper
Biomol rabbit anti-IRAK-4 was used to perform western blot in order to show that IRAK-1 blockade is important for tolerance of human DCs induced by TLR2 and TLR4 stimulation. more
total:22
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Life Technologies anti-IRF-3antibody was used to perform western blot in order to study IRF-3-dependent innate immunity more
total:4
Activation of anti-hepatitis C virus responses via Toll-like receptor 7. 2006 to the paper
Santa Cruz anti-IRF-7 antibody was used to perform western blot in order to study the mechanism of anti-HCV by TLR7 more
total:37
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. 2011 to the paper
Invitrogen anti-phospho-IRS (Y612) was used to perform western blot in order to show that Grb10 was indentified as a negative regulator of insulin signaling by phosphoproteomic analysis. more
total:13
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Upstate Irs2 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models more
total:7
Mycobacterial disease and impaired IFN-? immunity in humans with inherited ISG15 deficiency. 2012 to the paper
Santa Cruz Biotechnology anti-ISG15 was used to perform flow cytometry and immunocytochemistry in order to show that ISG15 deletion in humans impairs IFN-gamma immunity and results in mycobacterial disease susceptibility. more
total:3
Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation. 2009 to the paper
BD Biosciences Itch monoclonal antibody was used to perform western blot and immunoprecipitation in order to demonstrate the key mechanisms that regulate p63 protein stability in vivo. more
total:7
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
BD Biosciences anti-Btk/Itk (pY551/pY511) was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:5
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 to the paper
Calbiochem IP3R1 antibody was used in western blot and immunohistochemistry to study the role of molecular alterations in the cerebellum of the PMCA2-null in Purkinje neurons. more
total:2
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. 2005 to the paper
Santa Cruz Biotechnology goat anti-IP3R2 antibody was used in western blot to study the binding of phospholipid scramblase 1 to the promoter region of the inositol 1, 4, 5-triphosphate receptor type 1 more
total:193
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-JNK1 monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:22
Fibronectin fibrillogenesis regulates three-dimensional neovessel formation. 2008 to the paper
Cell Signaling Technologies anti-phospho-SAPK antibody was used to perform western blot in order to show that neovessel development can be regulated by fibronectin fibrillogenesis. more
total:5
Vascular precursors in developing human retina. 2008 to the paper
Assay Designs anti-SCF antibody was used to perform immunohistochemistry in order to study vascular precursors of human retina. more
total:19
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Abcam anti-Ku70 antibody was used to perform immunoblotting in order to studythe role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
total:22
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Life Technologies anti-Ku80 antibody was used to perform immunoprecipitation and immunofluorescence in order to study IRF-3-dependent innate immunity. more
total:11
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Upstate Biotechnology LAT antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts. more
total:18
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 to the paper
Upstate Biotechnology Lck antibody was used in western blot to study the role of flotillin-1 in chemokine receptor signaling and receptor partitioning with lipid rafts. more
total:4
Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer. 2007 to the paper
Transduction Laboratories anti-LIMK1 antibody was used in western blot and immunohistochemistry to study the role of LIM kinase 1 in reversible G1/S phase arrest, chromosomal instability and prostate cancer. more
total:2
Quantitative proteomic analysis by iTRAQ(R) for the identification of candidate biomarkers in ovarian cancer serum. 2010 to the paper
R&D Systems anti-lipopolysaccharide binding protein-1 antibody was used to perform western blot in order to study the identification of candidate biomarkers by iTRAQ® analysis in ovarian cancer serum. more
total:20
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 to the paper
Santa Cruz anti-Lyn 44 antibody was used to perform western blot in order to study the roles of the lipid raft-dependent Fc secre tRI ubiquitination in the regulation of receptor endocytosis. more
total:4
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 to the paper
Santa Cruz Biotechnology anti-NIK monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation more
total:4
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 to the paper
Abgent rabbit anti-JNK3 antibody was used to perform western blot in order to study the effect of TNF-alpha on gamma-secretase. more
total:10
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 to the paper
Cell Signaling Technologies phospho-specific and total anti-p38antibody was used to perform western blot in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis. more
total:2
Activation of p38 has opposing effects on the proliferation and migration of endothelial cells. 2005 to the paper
Cell Signaling Technology polyclonal anti-p38 delta antibody was used in human umbilical vein endothelial cells (HUVECs) and in western blot to study the effect of enhanced p38 MAPK activity on endothelial cell function. more
total:1
Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria. 2009 to the paper
Cell Signaling Technology rabbit polyclonal anti-VISA antibody was used in western blot to study the effect of gC1qR on RIG-I and MDA5-dependent antiviral response at mitochondria.
total:4
High prevalence of mannose-binding lectin (MBL) deficiency in premature neonates. 2006 to the paper
Sanquin biotinylated mouse-anti-MBL IgG 5E12 (10 ug/ml) was used in ELISA assay as the detection antibody to measure MBL in plasma to study the high prevalence of mannose-binding lectin (MBL) deficiency in premature neonates more
total:38
TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. 2010 to the paper
Calbiochem anti-Hdm2 antibody was used for western blot in order to investigate the role of TGFB1 in the regulation of Mdm2 expression and late-stage breast cancer metastasis. more
total:6
A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation. 2006 to the paper
Santa Cruz monoclonal anti-MEF2 antibody was used in immunoprecipitation to study a mechanism underlying postsynaptic differentiation that may modulate activity-dependent synapse development and plasticity in the brain.. more
total:3
c-MYC independent nuclear reprogramming favors cardiogenic potential of induced pluripotent stem cells. 2010 to the paper
Proteintech rabbit anti-Mef2c antibody (10056-1-AP; dilution 1:50) was used to perform immunocytochemistry in order to determine the relationship between the cardiogenic potential of iPS and the nuclear reprogramming. more
total:57
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 to the paper
Cell Signaling Technology anti-MEK1 antibody was used to perform flow cytometry and immunochemistry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10. more
total:16
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. 2010 to the paper
Cell Signaling Technologies anti-phospho-MEK1/2 antibody was used to perform western blot in order to study the discrimination between the yeast and hyphal forms of C. albicans in epithelial cells via a biphasic MAPK response. more
total:15
Mxi2 promotes stimulus-independent ERK nuclear translocation. 2007 to the paper
Santa Cruz rabbit polyclonal anti-MEK antibody was used in western blot to show that Mxi2 has profound effects on ERK1/2 nucleocytoplasmic distribution, promoting their accumulation in the nucleus. more
total:18
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
Cell Signaling Technology anti-MAPKAPK 2 (pT334) was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:15
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia. 2008 to the paper
Cell Signaling Technology polyclonal rabbit MKK3 with phosphorylated serine 189 antibody was used in western blot in order to demonstrate that ATM undergoes an activating phosphorylation in syncytia elicited by the envelope glycoprotein complex (Env) of human immunodeficiency virus-1 (HIV-1) in vitro more
total:9
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia. 2008 to the paper
Cell Signaling Technology polyclonal rabbit MKK6 with phosphorylated serine 207 antibody was used in western blot in order to demonstrate that ATM undergoes an activating phosphorylation in syncytia elicited by the envelope glycoprotein complex (Env) of human immunodeficiency virus-1 (HIV-1) in vitro more
total:2
Perturbation of the P-body component Mov10 inhibits HIV-1 infectivity. 2010 to the paper
Proteintech Group anti-Mov10 antibody was used to perform western blotting in order to study if overexpression of Mov10 in cells would inhibit HIV-1 infectivity. more
total:19
The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection.. 2009 to the paper
Calbiochem rabbit polyclonal Mre11 antibody was used to perform western blot in order to investigate the relations between E1B-55K/E4orf6 and eIF2. more
total:33
A gene signature-based approach identifies mTOR as a regulator of p73. 2008 to the paper
Santa Cruz polyclonal anti-mTOR (N-19 (alpha-FRAP) was used to perform western blot in order to show that mTOR is identified as a regulator of p73 by a gene signature-based approach. more
total:3
Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. 2008 to the paper
eBioscience rabbit MyD88 antibody was used to perform western blot in order to study TLR2 and TLR4 expression in monocytes from T1DM patients. more
total:3
Overexpression of the mitochondrial T3 receptor p43 induces a shift in skeletal muscle fiber types. 2008 to the paper
Alexis Biochemical monoclonal MyHC type IIa antibody was used in immunohistochemistry in order to examine the role of mitochondrial T3 receptor p43 in vivo muscle development and phenotype more
total:3
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. 2009 to the paper
Sigma anti-NMHC-IIA antibody was used to perform western blot in order to study the assemble of mammalian nonmuscle myosin II in live cells. more
total:1
Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility. 2007 to the paper
Sigma rabbit polyclonal anti-myosin V antibody was used to carry out western blot analysis in order to investigate the role for UNC-45 in the regulation of tumor cell proliferation and metastasis.
total:1
BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity. 2005 to the paper
Genemed anti-myosin IXb antibody made against the C-terminal peptide CSASTESLLEERAVRGAAEE was used in western blot to study the role of BIG1 as a binding partner of myosin IXb to regulate its Rho-GTPase activating protein activity.
total:4
Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. 2007 to the paper
BD Biosciences NFATc1 antibody was used in immunohistochemistry to study the role of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. more
total:5
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Cell signaling rabbit anti-NFAT1 antibody was used to perform immunocytochemistry in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
total:4
Nuclear factor of activated T cells and serum response factor cooperatively regulate the activity of an alpha-actin intronic enhancer. 2005 to the paper
Santa Cruz Biotechnology mouse monoclonal anti-NFATc3 antibody was used in western blot and immunoprecipitation to detect NFATc3 in HEK293 cells treated with ionomycin and PMA. more
total:11
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
New England Biolabs anti-p52/p100 (18D10) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:7
A critical role for CHIP in the aggresome pathway. 2009 to the paper
Santa Cruz NFKBIB antibody was used for Western blotting in order to study the critical role for CHIP in the aggresome pathway. more
total:5
NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. 2010 to the paper
BD Pharmingen monoclonal anti-NKG2D-allophycocyanin antibody was used to perform flow cytometry in order to show multiple CD3 Zeta-dependent receptor functions can be impaired simultaneously by pathological NKG2D ligand expression. more
total:1
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. 2006 to the paper
Alexis rabbit polyclonal anti-Nalp3 antibody (which recognizes WT, R260W, and D303N cryopyrins) was used in human cells and in immunocytochemistry to study the role of cryopyrin and pyrin in activating caspase-1.
total:2
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. 2006 to the paper
Cayman Chemical NOD2-specific rabbit antiserum was used in immunoprecipitation and western blot to measure its expression in primary keratinocytes and transfected HEK293 cells. more
total:4
Selectively oncolytic mutant of HSV-1 lyses HeLa cells mediated by Ras/RTN3. 2007 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-Ras antibody was used in western blot to study mechanism mtHSV was targeted for treating tumors but not other organs. more
total:3
Immortalization and characterization of lineage-restricted neuronal progenitor cells derived from the porcine olfactory bulb. 2008 to the paper
Abcam rabbit anti-neuregulin-1 antibody (1:100) was used in immunocytochemistry in order to study the role of CCR5 in the migration of pulmonary fibrocytes and the promotion of metastasis more
total:10
Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. 2008 to the paper
R&D Systems monoclonal anti-Nur77 was used to perform immunocytochemistry in dilution 1:200 in order to show that acetylshikonin and analogues induce apoptosis through orphan nuclear receptor Nur77-mediated apoptotic pathway in cancer cells. more
total:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Cell Signalling anti-p110alpha was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:178
Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. 2012 to the paper
Abcam mouse anti-p21 antibody was used to perform western blot in order to study the mechanism through which doxorubicin suppressed tumor growth. more
total:118
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. 2012 to the paper
BD Pharmingen anti-p27CDKN1B antibody was used to perform western blot in order to show that p53-dependent cell proliferation and survival could be regulated by atg7. more
total:2
Regulation by P2X7: epithelial migration and stromal organization in the cornea. 2008 to the paper
Lifespan Biosciences P2X7 antibody was used in immunohistochemistry in order to study the role of the P2X7 receptor in the repair of in vivo corneal epithelial debridement wounds more
total:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 to the paper
Santa Cruz anti-p300 was used to perform western blot and ChIP assays in order to show that acetylation of AML1-ETO fusion protein by p300 is critical for leukemogenesis. more
total:189
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 to the paper
Biosource International anti-p38 antibody was used to perform western blot in order to study the effect of NFAT5 on hyperosmolar stressed human limbal epithelial cells. more
total:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 to the paper
Santa Cruz Biotechnology anti-p50 antibody was used to perform ChIP assay in order to show that viral replication was inhibited by the elevated IL-32 levels during influenza virus infections. more
total:146
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 to the paper
Santa Cruz anti-p65 antibody was used to perform immunofluorescence in order to study the role of DNA-dependent protein kinase in the IRF-3-dependent innate immunity. more
total:43
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Upstate anti-p85 pAb was used to perform immunoprecipitation to the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:20
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 to the paper
Santa Cruz anti-RSK-1 antibody (1:1,000) was used to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediates anti-apoptotic effects. more
total:29
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 to the paper
Epitomics rabbit monoclonal anti-Pak1 antibody was used in western blot to identify Pak4 as a novel Gab1-interacting protein downstream from the Met receptor and to study its function. more
total:6
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 to the paper
Santa Cruz Biotechnology anti-PAK-2 antibody was used for western blot in order to investigate the role of PAK-2 in the regulation of anticancer drug-induced cell apoptosis. more
total:1
Regulation by P2X7: epithelial migration and stromal organization in the cornea. 2008 to the paper
Santa Cruz Biotechnology pannexin-1 antibody was used in immunohistochemistry in order to study the role of the P2X7 receptor in the repair of in vivo corneal epithelial debridement wounds
total:2
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. 2006 to the paper
Chemicon PDE1B1 antibody was used in western blot to study Cellular and subcellular localization of PDE10A. more
total:5
Antiangiogenic characteristics of astrocytes from optic nerve heads with primary open-angle glaucoma. 2008 to the paper
Santa Cruz Biotechnology anti-PDGF-A polyclonal antibody was used to perform western blot in order to study the role of astrocytes on angiogenesis. more
total:5
Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. 2008 to the paper
Santa Cruz Biotechnology rabbit anti-PDGF-B antibody was used in immunohistochemistry to study whether the expression of tyrosine kinase growth factor receptors is constant or varies between and within individual colon cancer neoplasms. more
total:14
PDGFRalpha/beta expression correlates with the metastatic behavior of human colorectal cancer: a possible rationale for a molecular targeting strategy. 2008 to the paper
Santa Cruz Biotechnology anti-PDGFRA antibody was used to perform Western Blot and immunohistochemistry in order to prove that the metastatic behavior of human colorectal cancer correlates with PDGFRalpha/beta expression. more
total:27
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy. 2009 to the paper
Abgent anti-p-PDGFR Tyr579 antibody was used in immunohistochemistry in order to investigate the mechanism of how Akt mediates sterol regulatory element-binding protein 1 (SREBP-1) cleavage induced by EGFR. more
total:3
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. 2009 to the paper
Abgent anti-PI3KC3 antibody was used in western blot in order to study the role of Beclin 1 in the regulation of autophagy. more
total:6
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz polyclonal anti-p110beta antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:5
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 to the paper
Santa Cruz anti-p110delta monoclonal antibody was used to perform immunoprecipitation to study the role of phosphoinositide 3-kinase in the regulation of cytokine-dependent cell survival more
total:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Millipore polyclonal anti-human p85 antibody was used to carry out western blot analysis in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:1
Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. 2008 to the paper
Abgent rabbit anti-hVps15 antibody was used in western blot to identify the pathway and mechanism by which AAs signal to hVps34 to stimulate mTOR complex1 signaling.
total:2
Phosphorylation of serine 147 of tis21/BTG2/pc3 by p-Erk1/2 induces Pin-1 binding in cytoplasm and cell death. 2005 to the paper
Santa Cruz Biotechnology anti-Pin-1 antibody was used in immunoprecipitation to study the interaction of tis21 protein with Pin-1 after phosphorylation of its Ser147 residue by p-Erk1/2. more
total:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 to the paper
Santa Cruz Biotechnology rabbit anti-PKCAalpha antibody was used in western blot in order to study the function of TMX3 in eye development. more
total:35
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. 2009 to the paper
Santa Cruz Biotechnology anti-PKCdelta antibody was used in western blot to study the mechanism underlying PKCalpha suppressing tumor in the intestine. more
total:20
GABAA receptor trafficking is regulated by protein kinase C(epsilon) and the N-ethylmaleimide-sensitive factor. 2010 to the paper
Santa Cruz Biotechnology goat anti-PKC epsilon antibody was used to perform western blot and immunocytochemistry in order to show that NSF and PKC epsilon could regulate GABAA receptor trafficking to affect synaptic inhibition. more
total:32
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 to the paper
Santa Cruz Biotechnology polyclonal anti-PLCG1 antibody was used to carry out western blot analysis and immunoprecipitation assays in order to investigate the role of PIP5K1alpha in extracellular calcium induced generation of the second messengers IP3 and keratinocyte differentiation. more
total:1
Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway. 2005 to the paper
Novus Biologicals PLD2 antibody was used in immunoprecipitation to study ABCA1 phosphorylation and degradation
total:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate monoclonal anti-PP2Ac antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 to the paper
Upstate polyclonal anti-PP2A-A antibody was used in western blot in order to study the abnormal hyperphosphorylation of tau and its possible causes in adult DS brains more
total:2
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. 2007 to the paper
Sigma-Aldrich polyclonal antibody to the PP2APR65 subunit was used to perform western blot in order to investigate the functions of salt-inducible kinase-1. more
total:4
Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis. 2009 to the paper
Sigma-Aldrich anti-calcineurin A antibody was used in western blot in order to deduce that calcineurin activity and apoptosis of leukemic lymphocytes can be modulated by GC-mediated upregulation of RCAN1-1. more
total:2
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. 2005 to the paper
Chemicon rabbit anti-calcineurin antibody was used in immunohistochemistry to study the mechanisms that trigger astrocyte activation. more
total:3
Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. 2006 to the paper
Sigma CnB1 antibody was used in western blot to demonstrate direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. more
total:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 to the paper
Santa Cruz Biotechnology polyclonal rabbit anti-PKA catalytic subunit antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells. more
total:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 to the paper
Santa Cruz Biotechnology anti-the catalytic D subunit of PKA antibody C-20 was used in human fibrosarcoma HT1080 cells and in western blot to study the role for tyrosine phosphorylation in full-scale activation of the eIF2alpha RNA-dependent protein kinase. more
total:9
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIalpha was used in immunohistochemistry to detect the PKA subunit RIalpha in human adrenal samples more
total:9
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 to the paper
Santa Cruz Biotechnology anti-PKA RII antibody was used in immunoprecipitation in order to study the role of PP2A in limiting PKA phosphorylation of phospholamban and TnI for myocyte contraction responses under beta1AR stimulation more
total:3
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 to the paper
EMD Biosciences monoclonal antibody specific for RIIbeta was used in immunohistochemistry to detect the PKA subunit RIIbeta in human adrenal samples more
total:12
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. 2007 to the paper
Cell Signaling Technology phospho-Pan-PKC antibody (1:1,000) was used in western blot to study melanoma cell motility by the Wnt5A/protein kinase C pathway through the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition more
total:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 to the paper
Cell Signaling Technology anti-phospho-PKCtheta antibody was used in western blot to demonstrate that CCL2 induces brain endothelial hyperpermeability via Rho/PKCalpha signal pathway interactions. more
total:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Neomarkers PTEN antibody was used to perform immunohistochemistry in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 to the paper
Millipore anti-Rac1 monoclonal antibody (1:1,000) was used to perform immunoblot in order to study the metastasis suppressed by Rho GDP dissociation inhibitor 2 (RhoGDI2) through Rho GTPases. more
total:46
MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. 2010 to the paper
Santa Cruz Biotechnology anti-RAF1 antibody was used to perform western blot in order to study the role of microRNA-7 in tongue squamous cell carcinoma cells. more
total:20
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 to the paper
Oncogene Ras antibody was used to perform western blot in order to clarify that Skp2 involved in the p19Arf-p53 pathway independent cellular senescence. more
total:3
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. 2010 to the paper
Cell Signaling Technology anti-rictor antibody was used to carry out western blot analysis in order to investigate the precise contribution of 4E-BPs to mTORC1 signaling. more
total:9
Repression of NF-kappaB and activation of AP-1 enhance apoptosis in prostate cancer cells. 2009 to the paper
Santa Cruz Biotechnology anti-RIP antibody was used in western blot to study the effect of repression of NF-kB and activation of AP-1 on apoptosis in prostate cancer cells. more
total:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 to the paper
Santa Cruz Biotechnology anti-ubiquitin antibody was used in western blot in order to identify a novel complex of erasin-ubiquilin-p97/VCP and its function in ERAD. more
total:9
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 to the paper
Cell Signaling anti-phosphorylated p90RSK antibody was used to perform western blot in order to study the important role of GRK4 in D3 receptor's signaling in human proximal tubule cells. more
total:9
Mitogen-activated protein kinase-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection. 2009 to the paper
Santa Cruz anti-RSK2 antibody was used to perform western blot in order to study the role of RSK2 in the cellular antiviral response. more
total:3
Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation. 2009 to the paper
Santa Cruz Biotechnology MSK1 antibody was used in western blot in order to study the role of MSK1 in NF-kB activation and inflammatory diseases more
total:2
Hypoxia-induced energy stress inhibits the mTOR pathway by activating an AMPK/REDD1 signaling axis in head and neck squamous cell carcinoma. 2008 to the paper
Cell Signaling Technology rabbit polyclonal anti-phospho-p70 S6 kinase (Thr389) antibody was used for western blot in order to investigate the role of hypoxia-induced energy stress in the regulation of mTOR pathway in head and neck squamous cell carcinoma1. more
total:1
Expression of receptor for advanced glycation end products in sarcoid granulomas. 2007 to the paper
Santa Cruz Biotechnologies S-100 A12 antibody was used in immunohistochemistry (1:4,000) to study the expression of receptor for advanced glycation end products in sarcoid granulomas
total:23
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 to the paper
BD anti-mouse S100B antibody (1:1000) was used in immunocytochemistry in order to investigate the roles of Nkx2.2 and Nkx6.2 in the regulation of myelin sheath formation. more
total:20
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. 2012 to the paper
Cell Signalling anti-ShcA and anti-phospho-ShcA (Tyr239/240) antibodies were used to perform western blot in order to study the effect of the facilitation of AMPA receptor synaptic delivery on cognitive enhancement. more
total:34
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 to the paper
Santa Cruz Biotechnology polyclonal anti-Shp2 antibody was used to perform western blot in order to study Notch signaling auto-amplification in macrophages which was regulated by TLR and RBP-J. more
total:4
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 to the paper
BD Biosciences anti-SLP-76 (BLNK)(pY128) was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry. more
total:11
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 to the paper
Santa Cruz rabbit Sos-1 antibody was used in western blot to study the role of Abi-1 in morphogenesis and synapse formation. more
total:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 to the paper
Calbiochem anti-SRC antibody was used to perform western blot in order to study the estrogen sensitivity and the acquisition of antiestrogen resistance in luminal breast cancer. more
total:15
Regulation of telomerase activity by interferon regulatory factors 4 and 8 in immune cells. 2009 to the paper
Santa Cruz anti-Stat6 antibody was used to perform western blot in order to show that IRF-4 and IRF-8 can increase telomerase activity. more
total:12
Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk.. 2008 to the paper
Santa Cruz Biotech anti-Syk antibody was used to perform western blot in order to study the interaction between NS5A and Syk. more
total:5
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 to the paper
Santa Cruz goat anti-Tab1 antibody was used to perform western blotting in order to determine the role of NRAGE in regulating NF-kappaB activity. more
total:2
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TAB2 monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:10
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 to the paper
Santa Cruz mouse anti-Tak1 antibody was used to perform western blotting in order to determine the role of NRAGE in regulating NF-kappaB activity. more
total:7
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. 2011 to the paper
Epitomics anti-pTBK1pS172 was used to perform western blot in order to show that Salmonella enterica growth was restricted by phosphorylation of autophagy receptor optineurin. more
total:15
TXNL6 is a novel oxidative stress-induced reducing system for methionine sulfoxide reductase a repair of α-crystallin and cytochrome C in the eye lens. 2010 to the paper
Abcam Trx 1 antibody (1:1000) was used to perform western blot and immunocytochemistry in order to clarify a critical role for TXNL6 in MsrA repair of essential lens proteins under oxidative stress conditions and that TXNL6 is important for MsrA defense protection against cataract. more
total:1
Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. 2008 to the paper
eBioscience rabbit Trif antibody was used to perform western blot in order to study TLR2 and TLR4 expression in monocytes from T1DM patients.
total:3
Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis.. 2008 to the paper
Santa Cruz Biotechnology rabbit polyclonal TLR1 antibody (2 ug/ml) was used in western blot in order to study the role of toll-Like receptors in the pathogenesis of lyme neuroborreliosis more
total:22
Inflammatory role of Toll-like receptors in human and murine adipose tissue. 2010 to the paper
Hycult Biotechnologies monoclonal anti-TLR2 was used to perform ELISA in order to show that Toll-like receptors in human and murine adipose tissue participate omental adipose tissue-related inflammation. more
total:9
Expression of Toll-like receptors in verruca and molluscum contagiosum. 2008 to the paper
Santa Cruz Biotechnology goat polyclonal anti-human TLR3 was used in immunohistochemistry to study the expression of toll-like receptors in verruca and molluscum contagiosum in cryostat sections from human skin. more
total:37
Role of Toll-like receptor 4 and human defensin 5 in primary endocervical epithelial cells. 2010 to the paper
R&D mouse monoclonal anti-TLR4 antibody was used to perform western blot in order to study the immune defence role of TLR4 and HD5 in primary endocervical epithelial cells. more
total:4
Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis.. 2008 to the paper
Santa Cruz Biotechnology rabbit polyclonal TLR5 antibody (2 ug/ml) was used in western blot in order to study the role of toll-Like receptors in the pathogenesis of lyme neuroborreliosis more
total:3
Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance. 2010 to the paper
Alexis polyclonal anti-TLR7 was used to perform flow cytometry and immunohistochemistry in order to study whether TLR7 and TLR8 expressed by human lung cancer cells induced cell survival and chemoresistance. more
total:2
Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance. 2010 to the paper
Alexis monoclonal PE-conjugated anti-TLR8 antibodies and anti-TLR8 were used to perform flow cytometry and immunohistochemistry respectively in order to study whether TLR7 and TLR8 expressed by human lung cancer cells induced cell survival and chemoresistance. more
total:6
Expression of Toll-like receptors in verruca and molluscum contagiosum. 2008 to the paper
Santa Cruz Biotechnology goat polyclonal anti-human TLR9 was used in immunohistochemistry to study the expression of toll-like receptors in verruca and molluscum contagiosum in cryostat sections from human skin. more
total:26
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TRAF2 (C-20) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:13
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TRAF3 (C-20) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:17
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 to the paper
Santa Cruz Biotechnology anti-TRAF6 (H-274) monoclonal antibody was used to perform western blot in order to study TNIK plays what role and how it play this role for canonical NF-kB and JNK signaling in B-cells. more
total:2
Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis. 2008 to the paper
EMD Chemicals anti-TRB3 antibody was used to perform western blot in order to study the response of the mTORC1 signaling after the inhibition of protein synthesis. more
total:2
Suppression of Sproutys has a therapeutic effect for a mouse model of ischemia by enhancing angiogenesis. 2009 to the paper
Santa Cruz Biotechnology anti-VEGFR-2 antibody was used for western blot in order to investigate the role of sproutys in the regulation angiogenesis and ischemia in mice. more
total:26
Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression. 2010 to the paper
Epitomics anti-TSC2 antibody was used to perform western blot and immunoprecipitation in order to study the mechanism by which carboxy terminal tail of polycystin-1 repress mTOR signaling via membrane retention of TSC2. more
total:2
Protective effects of a compound herbal extract (Tong Xin Luo) on free fatty acid induced endothelial injury: implications of antioxidant system. 2008 to the paper
Cell Signaling anti-thioredoxin interacting protein (Txnip) antibody was used in western blot to study the protective role of a compound herbal extract (Tong Xin Luo) on free fatty acid induced endothelial injury. more
total:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 to the paper
Enzo Life Sciences anti-Ubiquitin antibody was used to perform western blot in order to study synaptic plasticity. more
total:1
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes. 2007 to the paper
Boston Biochem anti-UbcH5 antibody was used to perform immunoprecipitation in order to study the roles of the DET1 during the regulation of the Cul4A activity.
total:1
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes. 2007 to the paper
Boston Biochem anti-UbcH5 antibody was used to perform immunoprecipitation in order to study the roles of the DET1 during the regulation of the Cul4A activity.
total:1
Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. 2010 to the paper
Abcam anti-UbcH5c antibody was used to perform western blot in order to study the mechanism of A20 action in the inhibition of NF-kappaB signaling.
total:1
Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. 2010 to the paper
Abcam anti-UbcH5c antibody was used to perform western blot in order to study the mechanism of A20 action in the inhibition of NF-kappaB signaling.
total:1
A phosphorylation-acetylation switch regulates STAT1 signaling. 2009 to the paper
Abgent UBCH8antibody was used for western blot in order to investigate the role of phosphorylation-acetylation switch in the regulation of STAT1 signaling.
total:1
A phosphorylation-acetylation switch regulates STAT1 signaling. 2009 to the paper
Abgent UBCH8antibody was used for western blot in order to investigate the role of phosphorylation-acetylation switch in the regulation of STAT1 signaling.
total:3
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 to the paper
Invitrogen anti-Ubc13 was used to perform western blot in order to show that RHINO is important for ATR activation during DNA damage responses. more
total:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 to the paper
Cell Signaling Technology mouse anti-ubiquitin monoclonal antibody was used in western blot in order to demonstrate that BCL6 interacts with HB-EGF-CTF and that this interaction might induce the cyclin D2 expression in human gastric cancer. more
total:2
Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. 2008 to the paper
Upstate Biotechnology anti Vav3 antibody was used in western blot and immunohistochemistry to study the activation of estrogen receptor by Vav3 oncogene and Vav3 overexpression in human breast cancer more
total:4
The effect of RGD peptides on osseointegration of hydroxyapatite biomaterials. 2008 to the paper
Santa Cruz vitronectin antibody was used in western blot in order to study the effect of RGD peptides on osseointegration of hydroxyapatite biomaterials more
total:1
EspF Interacts with nucleation-promoting factors to recruit junctional proteins into pedestals for pedestal maturation and disruption of paracellular permeability. 2008 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti-WASP antibody was used in western blot to study the role for EspF in pedestal maturation and the disruption of paracellular permeability.
total:3
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 to the paper
Chemicon Wave antibody was used in western blot to study the role of Abi-1 in morphogenesis and synapse formation. more
total:2
Increased expression of Wiskott-Aldrich syndrome protein family verprolin-homologous protein 2 correlated with poor prognosis of hepatocellular carcinoma. 2006 to the paper
Santa Cruz Biotechnology goat polyclonal anti-human WAVE2 antibody (c-14) was used in protein and paraffin sections from human tumor, and which were used in western blot and immunohistochemistry, to study the relationship between Wiskott-Aldrich syndrome protein family verprolin-homologous protein 2 and poor prognosis of hepatocellular carcinoma. more
total:2
The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle. 2005 to the paper
Santa Cruz Biotechnology goat polyclonal Cdc42 antibody was used in western blot and immunoprecipitation to study the role of the adapter protein CrkII in the regulation of N-WASp and Cdc42 activation. more
total:6
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 to the paper
Upstate rabbit anti-Yes1 (06.514) polyclonal antibody was used to perform western blot and immunocytochemistry in order to investigate the molecular mechanisms underlying CRMP2 function in CXCL12-induced T lymphocyte migration. more