Inflammasomes
gene
reagent
sample publication
sample review
APP
amyloid beta precursor protein
total:81
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 to the paper
Chemicon anti-APP was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics. more
Bcl 2
BCL2 apoptosis regulator
total:130
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 to the paper
Santa Cruz anti-Bcl-2 antibody (C-2, sc-7382, 1:500) was used to perform western blot in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors. more
Bcl-xL
BCL2 like 1
total:85
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. 2008 to the paper
Santa Cruz Biotechnology mouse anti-Bcl-XL monoclonal antibody was used to perform western blot in order to study the function of the natural product honokiol. more
caspase-1
caspase 1
total:7
Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI. 2008 to the paper
Santa Cruz Caspase-1 antibody was used in western blot in order to analyze changes in a subproteome of ~800 proteins in the promyelocytic leukemia cell line HL-60 upon treatment with the proteasome inhibitor PSI more
HSP90AB1
heat shock protein 90 alpha family class B member 1
total:8
Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. 2010 to the paper
Millipore anti-H3S28P antibody was used in western blot in order to investigate the mechanism of how the embryonic stem cells chromatin structure change was regulated by condensin complexes during mitotic progression. more
NLRP3
NLR family pyrin domain containing 3
total:1
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. 2006 to the paper
Alexis rabbit polyclonal anti-Nalp3 antibody (which recognizes WT, R260W, and D303N cryopyrins) was used in human cells and in immunocytochemistry to study the role of cryopyrin and pyrin in activating caspase-1.
P2X7
purinergic receptor P2X 7
total:2
Regulation by P2X7: epithelial migration and stromal organization in the cornea. 2008 to the paper
Lifespan Biosciences P2X7 antibody was used in immunohistochemistry in order to study the role of the P2X7 receptor in the repair of in vivo corneal epithelial debridement wounds more
PANX1
pannexin 1
total:1
Regulation by P2X7: epithelial migration and stromal organization in the cornea. 2008 to the paper
Santa Cruz Biotechnology pannexin-1 antibody was used in immunohistochemistry in order to study the role of the P2X7 receptor in the repair of in vivo corneal epithelial debridement wounds
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
SGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
thioredoxin
total:15
TXNL6 is a novel oxidative stress-induced reducing system for methionine sulfoxide reductase a repair of α-crystallin and cytochrome C in the eye lens. 2010 to the paper
Abcam Trx 1 antibody (1:1000) was used to perform western blot and immunocytochemistry in order to clarify a critical role for TXNL6 in MsrA repair of essential lens proteins under oxidative stress conditions and that TXNL6 is important for MsrA defense protection against cataract. more
TXNIP
thioredoxin interacting protein
total:2
Protective effects of a compound herbal extract (Tong Xin Luo) on free fatty acid induced endothelial injury: implications of antioxidant system. 2008 to the paper
Cell Signaling anti-thioredoxin interacting protein (Txnip) antibody was used in western blot to study the protective role of a compound herbal extract (Tong Xin Luo) on free fatty acid induced endothelial injury. more