IRS activation
gene
reagent
sample publication
sample review
DOK1
docking protein 1
total:3
Chemical rescue of a mutant enzyme in living cells. 2006 to the paper
Santa Cruz Biotechnology anti-Dok-1 antibody was used in western blot to study the protein tyrosine kinase Src R388A mutant rescued in live cells with the use of the small molecule imidazole. more
insulin
total:25
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. 2012 to the paper
Alpco insulin ELISA kit was used to perform ELISA in order to investigate the regulatory effect of iron oxide nanoparticles on blood glucose in mice. more
insulin receptor
total:22
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. 2009 to the paper
Santa Cruz Biotechnology rabbit polyclonal anti subunit of insulin receptors (IR) antibody was used in western blot and immunocytochemistry to test the hypothesis that insulin signaling provides a physiological defense mechanism against the synaptotoxicity of Abeta-derived diffusible ligands. more
IRS-1
insulin receptor substrate 1
total:37
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. 2011 to the paper
Invitrogen anti-phospho-IRS (Y612) was used to perform western blot in order to show that Grb10 was indentified as a negative regulator of insulin signaling by phosphoproteomic analysis. more
IRS-2
insulin receptor substrate 2
total:13
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 to the paper
Upstate Irs2 antibody was used in western blot in order to study the role of Gsk-3beta in control of beta-cell mass in insulin-resistant diabetic models more